Table of Content

16 July 2024, Volume 42 Issue 14

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Effects of "Jianhe Fuyuan Formula" Medicinal Liquor on Hair Follicle Growth and Estrogen and Androgen in C57BL/6 mice

LIU Dao-nan, HAN Li, QIU Xing-hua, DAI Xing-ye, CHENG Wang-yuan, ZHU Jian-wen, CHENG Kai

2024, 42(14):  1-4. 

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Objective To observe the related effects of Jianhe Fuyuan prescription wine on hair loss and regeneration, hair and anti-hair loss. Methods The mice were randomly divided into 7 groups: blank group, liquor group, normal saline treatment group, low dose of medicinal liquor group, high dose of medicinal liquor group, minoxidil group, high dose of medicinal liquor and minoxidil group. Except for the blank group and minoxidil group, the skin color, hair follicle structure, serum estradiol (E2) and testosterone (T) of mice were observed after 15 days of continuous administration. Results The low dose of Jianhe Fuyuan prescription wine can enhance the hair growth rate of mice, and can effectively promote the blackening of the skin of mice, so that the hair of mice can enter the growth period from the stationary phase, significantly increase the number of hair follicles, increase the dermal papilla, and penetrate into the internal tissues of the skin. Conclusion Jianhe Fuyuan prescription wine has the basic effect of hair loss regeneration, hair fixation and anti-hair loss.

The Effect of Tongguan Liqiao Acupuncture Therapy on Swallowing Function and Quality of Life in Patients with Dysphagia after Stroke

JIA Li-jun, WANG Li-na, FU Jin-huan, GONG Juan-juan

2024, 42(14):  5-8. 

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Objective To evaluate the effect of Tongguan Liqiao acupuncture in patients with dysphagia after stroke (DAS) and its influence on swallowing function and quality of life. Methods A total of 90 DAS patients admitted to the First People's Hospital of Pingyuan County from April 2021 to August 2022 were selected as the study objects, and were divided into control group (45 cases included and given routine rehabilitation training) and observation group (45 cases included, plus Tongguan Liqiao acupuncture) according to random number table method. Intergroup clinical response rate, WST, SSA, SWAL-QOL, blood oxygen saturation (SaO₂), ALB and Hb were evaluated. Results The clinical effective rate of the observation group was higher than that of the control group(P<0.05); (2) After 2 weeks of treatment, WST and SSA were lower and SWAL-QOL, SaO₂, ALB and Hb were higher in the observation group(P<0.05). Conclusion Tongguan Liqiaoacupuncture can improve the swallowing function, nutritional status, SaO₂ and quality of life in patients with DAS as soon as possible, which is worth promoting.

Clinical Effect of Pseudostellaria Formula Granules+Hydroxymetazoline Hydrochloride Spray in the Treatment of Children's Sinusitis

SHU Xiu-jin, ZHANg Kun, LI Feng-yao, CHENG Yao, XU Qing-ling, JIANG Zhou-wei

2024, 42(14):  8-11. 

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Objective To explore and analysis the clinical effects of Radix Pseudostellariae Formula Granules+Hydroxymetazoline Hydrochloride Spray in the treatment of children's Sinusitis. Methods A total of 80 cases of children with Sinusitis who were treated in n Bijie Traditional Chinese Medicine Hospital from September 2022 to June 2023 were selected as the study subjects. Accorded to the principle of 1:1 random envelope drawing, 80 children were divided into the Pseudostellaria group of 40 cases and the control group of 40 cases. Both groups of children were received endoscopic surgery. The control group were treated with hydroxymethylazoline hydrochloride spray, and the Pseudostellaria group were treated with Pseudostellaria formula granules on the basis of the control group. Both groups were observed for 4 weeks, and were to determine the treatment effects of the two groups of children. Results After 4 weeks of treatment, the total effective rates of the Pseudostellaria group were 97.50%, while the control group were 85.00%. The Pseudostellaria group were significantly higher than the control group (P<0.05). After 4 weeks of treatment, the pain VAS scores of the Pseudostellaria group and the control group were significantly lower than before treatment (P<0.05), and the pain VAS scores of the Pseudostellaria group after 4 weeks of treatment were also lower than the control group (P<0.05). After 4 weeks of treatment, the serum Interleukin 2 and Interleukin 6 levels in the Pseudostellaria group and the control group were significantly lower than those before treatment (P<0.05), and the serum Interleukin 2 and Interleukin 6 levels in the Pseudostellaria group after 4 weeks of treatment were also significantly lower than those in the control group (P<0.05). The incidence of adverse reactions such as epistaxis, nasal dryness, Sleep disorder and dizziness during the 4-week treatment period in the Pseudostellaria group were 5.00%, while that in the control group were 22.50%. The incidence of adverse reactions in the Pseudostellaria group were significantly lower than that in the control group (P<0.05). Conclusion Pseudostellaria formula granule+hydroxymethylazoline hydrochloride spray can alleviate clinical symptoms, improve the overall therapeutic effect of children with Sinusitis, inhibit the expression of serum Interleukin 2 and Interleukin 6, and reduce the incidence of adverse reactions.

Effect of Characteristic Acupuncture and Bilateral Acupoint Selection in Patients with Thoracic Outlet Syndrome

HU Hui-hui, LIU Yan-guan, XU Xiao-lei

2024, 42(14):  15-18. 

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Objective To explore the effect of characteristic acupuncture and bilateral acupoint selection in patients with thoracic outlet syndrome. Methods A total of 80 patients with thoracic exit syndrome admitted to Yulin Hospital of Traditional Chinese Medicine from January 2019 to April 2023 were selected for study, and divided into observation group and control group, with 40 cases in each group. Both groups of patients were treated with acupuncture, while the control group was treated with ordinary acupuncture. The observation group was treated with acupuncture based on the force and reaction forces, as well as the conduction effect of the force. Bilateral acupoint selection and bidirectional adjustment were used to compare the clinical efficacy of the two groups of patients. Changes in DASH Chinese upper limb function score and Pain Assessment Scale (VAS) scores before and after treatment, and comparing the quality of life level before treatment and after the overall course of treatment. Results The total response rate was significantly higher than that of the control group (P<0.05); after treatment, the scores of upper limb function and VAS decreased, while the observation group was lower (P<0.05); after treatment, mental health (MH), emotional intelligence (RE), social function (SF), vitality (VT), general health (CH), physical pain (BP), physical function (RP) and physical function (RE) related quality of life scores increased, and the observation group was higher than the control group (P<0.05). Conclusion Based on the action and reaction of force, as well as the conduction effect of force, acupuncture treatment using bilateral acupoint selection and bidirectional adjustment has a significant effect on the treatment of thoracic outlet syndrome. It can also improve the upper limb mobility function of patients, reduce pain levels, and improve their quality of life.

Effect of Xuansu Zhike Decoction Combined with Inhaled Glucocorticoid in the Treatment of Paediatric Bronchopneumonia and Its Effect on Serum VCAM-1 and Th1/Th2 Cytokines

SUN Wen-yan, ZHANG Su-ya, YANG Xi

2024, 42(14):  22-26. 

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Objective To investigate the therapeutic effect of Xuansu Zhike Decoction combined with inhaled glucocorticoid in the treatment of bronchial pneumonia in children and the influence of serum vascular intercellular adhesion molecule 1 (VCAM-1) and Th1/Th2 cytokines. Methods From May 2021 to May 2023,80 children of bronchopneumonia were selected. The random number table method was divided into two groups, 40 cases each. The control group was treated with glucocorticoids, and the test group was treated with glucocorticoids combined with Xuanwu cough soup. The time to disappearance of clinical symptoms was recorded in both groups of children, the clinical efficacy was evaluated, and the serum intercellular adhesion molecule-1 (VCAM-1), interferon (IFN) - γ, and interleukin (IL-4) levels were detected before and after treatment. Results Compared with the control group, The duration of cough, wheezing and shortness of breath decreased significantly (P<0.05), However, the fever disappearance time of the two groups was not significant difference(P>0.05); The overall response rate of the patients in the test group was 95.00%, The overall response rate of the control patients was 77.50%, The total response rate of patients in the test group was significantly higher than that in the control group (P<0.05); Compared with the control group, the serum IFN- γ, IL-4 and IFN- γ / IL-4 ratios improved significantly better than those of the control group (P<0.05), and the serum VCAM-1 was not significant difference(P>0.05); no significant adverse effects were seen in either group. Conclusion Xuansu cough relieving decoction combined with glucocorticoid in the treatment of pediatric bronchopneumonia can effectively promote the improvement of symptoms, improve clinical efficacy, and regulate the imbalance of Th1/Th2 cells.

The Value of Early Pregnancy Ultrasound Detection of NT Thickness in Screening for High Risk Prognosis of Down Syndrome

ZHANG Qiu-yan

2024, 42(14):  29-32. 

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Objective To explore and analysis the values of ultrasound detection of nuchaltranslucency (NT) thickness in early pregnancy to screen for a high risk prognosis of Down's syndrome (DS). Methods The study period were from August 2019 to February 2023, and 86 cases of high-risk postpartum women who underwent registered delivery n Beiliu People's Hospital were selected as the research subjects. They were divided into the high-risk group (DS screening risk values ≥ 1/270) and the low-risk group (DS screening risk value<1/270) based on the risk value of Down syndrome.All the parturients were given Ultrasonic testing to detect the NT thickness,and the serum pregnancy associated protein-A and Human chorionic gonadotropin levels of all the cases were detected to determine the prognosis. Results There were 20 cases with a risk value of Down syndrome ≥ 1/270 that accounted for 23.26%.The age, gestational week, gestational frequency, parity, systolic blood pressure,diastolic blood pressure,and fasting blood glucose of the high-risk group were not significantly different from those of the low-risk group and were not statistically significant (P>0.05). The serum levels of human chorionic gonadotropin in the high-risk group were significantly higher than those in the low-risk group (P<0.05), while the serum levels of pregnancy associated protein-A were lower than those in the low-risk group (P<0.05). Comparing the thickness of ultrasound NT, it was found that the data in the low-risk group and high-risk group were higher (P<0.05), with the NT thickening rate of 55.00% that were significantly higher than the 9.09% of the low-risk group (P<0.05). Logistic regression analysis showed that serum pregnancy associated protein-A, human chorionic gonadotropin content, and ultrasound NT thickness were important factors leading to a high risk of Down syndrome (95%CI：0.513-0.992、2.174-6.666、1.133-7.184,P<0.001).In the high-risk group of 20 cases, there were 5 cases were diagnosed as fetal chromosomal abnormalities by amniocentesis that accounted for 25.00%, among which 4 cases were NT thickening. ROC analysis showed that the maximum area under the curve of fetal chromosome abnormalities in high-risk prognosis of Down syndrome screened by Ultrasonic testing NT thickness in early pregnancy were 0.826. Conclusion The high risk population of Down's syndrome in the first trimester of pregnancy mostly shows the increase of serum Human chorionic gonadotropin content and the decrease of serum pregnancy related protein-A content, which are also accompanied by the increase of ultrasonic NT thickness. Ultrasonic testing NT thickness in the first trimester of pregnancy can effectively predict the prognosis of high-risk population of Down's syndrome.

A Comparative Study of Surgical Treatment of Early and Middle Stage Micro Thyroid Cancer

XIE Lei

2024, 42(14):  36-39. 

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Objective To compare the effectiveness of different surgical treatments for early to mid stage miniature thyroid cancer. Methods 88 microminiature thyroid cancer patients treated from February 2021 to February 2023 were selected as the research subjects, and all patients were divided into study group and control group according to different surgical methods, with 44 patients in each group.The control group received open thyroid surgery treatment,while the study group received endoscopic assisted thyroid surgery treatment.Recorded the plasma thyroid hormones and perioperative indicators of two groups of patients, as well as the changes in postoperative complications and pain scores. Results At 14 d (P<0.05), the total serum triiodothyronine was higher than 1 d before surgery (P<0.05). At 14 d after surgery, the serum parathyroid hormone and total triiodothyronine content of the study group were significant when compared with the control group (P<0.05). There was not significant (P>0.05).The study group's postoperative tube time, postoperative blood loss and postoperative hospital stay were significantly less than the control group, showing the statistically significant difference (P<0.05). The incidence of hypocalcemia, hoarseness, water cough, incision infection, recurrent laryngeal nerve injury was lower in the control group, with a statistically significant difference (P<0.05). The VAS scores of the study group at 1 d, 7 d and 14 d were lower than that of the control group, which the difference was significant (P<0.05). Conclusion Endoscopic assisted thyroid surgery can reduce postoperative catheterization time, intraoperative bleeding, postoperative hospitalization time, and reduce the incidence of complications in patients with early to mid stage miniature thyroid cancer. It can also reduce serum parathyroid hormone levels, increase serum total triiodothyronine content, and promote pain relief in patients.

Clinical Study on the Treatment of Mixed Hemorrhoids with Improved External Stripping and Internal Ligation Combined with Elastic Wire Ligation

MA Ning, QIN Li-li

2024, 42(14):  42-46. 

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Objective To study the therapeutic effect of modified external stripping and internal ligation combined with elastic wire ligation on patients with mixed hemorrhoids. Methods The 76 mixed hemorrhoids patients treated in Linyi Central Hospital from March 2022 to March 2023 were selected as the study subjects. And they were divided into two groups according to the order of admission. According to the order of patients' admission, they were divided into two groups A and B. Group A underwent traditional external stripping and ligation, while Group B underwent modified external stripping and ligation combined with elastic line ligation. The clinical indicators, main symptom scores, surgical treatment effect and postoperative complications of groups A and B were compared. Results The intraoperative bleeding in group A was greater than that in group B, significant (P<0.05). Operation duration, healing time and hospital stay in Group A were longer than Group B (P<0.05). Surgical wound pain and anal margin edema were more severe in group A than in group B (P<0.05). No significant difference was found between the two groups (P>0.05). Conclusion The improved external stripping and internal ligation combined with elastic wire ligation for mixed hemorrhoids is highly safe and can achieve ideal treatment results.

The Enlightenment of the Transformation of Mindfulness to the Clinical Application of Mind-regulation in Acupuncture

YANG Hua, XIE Kun-nan, HE Fu-cheng, TANG Bo

2024, 42(14):  58-60. 

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Mind-regulation is an important part in acupuncture and moxibustion therapy, however, no clear implementation plan and evaluation criteria have been formed. The successful transformation of mindfulness provides a enlightenment for the clinical application of mind-regulation. This article uses MBSR therapy as a reference, synthesizing existing literature, from the two aspects：the doctor’s and the patient’s behavior in the whole process of treatment, to put forward the implementation way of mind-regulation in clinical practice, to provide the reference for the future research and clinical practice of mind-regulation, and to promote the standardization of clinical operation and the improvement of curative effect of acupuncture and moxibustion.

Integration of Emotion Theory and Literary Therapy Thought in Neijing

JI Rui, LIU Hao-ran, CHEN Qian-feng

2024, 42(14):  61-64. 

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Based on the theoretical framework of literary therapy and the knowledge of treatment thought, etiology and pathogenesis in emotional medicine of traditional Chinese medicine, this paper discusses the integration of emotional theory and literary therapy in Huangdi Neijing, aiming at studying the content of emotional pathogenesis and treatment criteria in Neijing. At the same time, drawing on the concept of emotional competition in Neijing, this paper takes the literary creation subject and literary appreciation subject as the starting point, and through the development of literary and artistic activities, it can help the subject to vent their inner desires and emotions. In this way, people can deeply understand the role of emotion in physical health, and at the same time provide a richer theoretical basis for literary therapy.

A Comparative Study of the Application of the OBE Educational Concept Using the SPOC Combined with CBL Teaching Model and the Single-Use SPOC Teaching Model in the Teaching of Emergency Medicine in Traditional Chinese Medicine

CHEN Jun, CHEN Xing-yue, DENG Shi-kun, TAO Tian, DUAN Yu-chen, ZHANG Kai-chen, GAO Pei-yang

2024, 42(14):  74-77. 

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Objective To explore the comparative effectiveness of using the SPOC combined with CBL teaching model and the single-use SPOC teaching model in the teaching of "Emergency Medicine in Traditional Chinese Medicine" based on the OBE educational concept. Methods A total of 82 students majoring in traditional Chinese medicine at Chengdu University of Traditional Chinese Medicine participated in the study, taking the course "Emergency Medicine in Traditional Chinese Medicine" from September 2021 to February 2022. They were randomly divided into two groups: 41 students in the control group using the SPOC teaching model and 41 students in the observation group using the SPOC combined with CBL teaching model. The teaching effectiveness of the two groups was assessed based on theoretical exam scores, case analysis scores, and teaching satisfaction. Results There was no significant difference between the control group and the observation group in terms of theoretical exam scores (P>0.05). However, the observation group's case analysis scores were significantly higher than those of the control group, with a statistically significant difference (P<0.05). Additionally, the observation group's satisfaction with the teaching was significantly higher than that of the control group, with a statistically significant difference (P<0.05). Conclusion the use of the SPOC combined with CBL teaching model based on the OBE educational concept can significantly enhance students' ability to analyze and solve clinical problems compared to the single-use SPOC teaching model. This approach is also well-received by students and merits widespread application.

The predictive value of SOD, GSH-Px, MDA, MPO in the occurrence of epilepsy after cerebrovascular disease

YAN Li, PAN Lan-lan, GU Shue

2024, 42(14):  89-92. 

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Objective To explore the predictive value of Superoxide dismutase (SOD), Glutathione peroxidase (GSH Px), Malondialdehyde (MDA), Myeloperoxidase (MPO) and epilepsy after cerebrovascular disease. Methods 180 patients with Cerebrovascular disease admitted to Helan County People's Hospital from June 2018 to June 2023 were selected as the study subjects. They were divided into epilepsy group (n=28) and non epilepsy group (n=152) according to whether epilepsy occurred after the occurrence of cerebrovascular disease. In addition, 30 healthy volunteers who came to Helan County People's Hospital for physical examination at the same time were selected as the control group. Compare the expression levels of SOD, GSH-Px, MDA, and MPO among three groups of subjects, and use logistic regression analysis to analyze the predictive value of SOD, GSH-Px, MDA, and MPO for the occurrence of epilepsy after cerebrovascular disease. Subsequently, 28 patients with epilepsy after cerebrovascular disease were divided into two subgroups based on the type of seizure, namely the partial seizure group (n=15) and the systemic tetanic spasm group (n=13). And Spearman correlation analysis was used to analyze the correlation between SOD, GSH-Px, MDA and MPO and seizure severity after cerebrovascular disease. Result The levels of SOD and GSH-Px in the epilepsy group were significantly lower than those in the non epilepsy group and control group, while the levels of MDA and MPO were significantly higher than those in the non epilepsy group and control group (P<0.05); Logistic regression analysis showed that the decrease of SOD, GSH Px and the increase of MDA and MPO were independent factors influencing Seizure after cerebrovascular disease (P<0.05); The levels of SOD and GSH-Px in patients with generalized tonic spasm were lower than those in the partial seizure group, while the levels of MDA and MPO were higher than those in the partial seizure group (P<0.05); The Spearman correlation analysis results showed that SOD, GSH-Px were negatively correlated with the severity of epilepsy after cerebrovascular disease, while MDA, MPO were positively correlated with the severity of epilepsy after cerebrovascular disease (P<0.05). Conclusion The observation of serum SOD, GSH Px, MDA, MPO levels can predict the occurrence of epilepsy after cerebrovascular disease, and the lower the level of SOD, GSH Px and the higher the level of MDA, MPO, the more serious the seizure in patients with such cerebrovascular disease. Therefore, in clinical practice, relevant measures should be taken in time to prevent epilepsy and reduce the severity of seizure after cerebrovascular disease.

The Application Effect of Physique Identification Nursing in Pediatric Mycoplasma Pneumonia Infection

SUI Yi-ping LIU Jing LI Ya-qun LIU Jin-hua

2024, 42(14):  96-99. 

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Objective To explore the application effect of physique identification nursing in children with Mycoplasma pneumonia. Methods A total of 120 children with mycoplasma pneumoniae infection admitted to Weifang Hospital of Traditional Chinese Medicine from April 2021 to May 2022 were selected as the research subjects, and the children were divided into control group and observation group according to the random number table method, with 60 cases in each group.Targeted specialist medical records were established in both groups, and the treatment plan was the same.The observation group is given a traditional Chinese medicine nursing model based on constitution recognition, while the control group is given routine nursing paths and health education. Compare the cough symptom scores of two groups of Mycoplasma pneumonia infection; Calculate the recovery time of body temperature, disappearance time of shortness of breath, and disappearance time of rale in two groups; Further investigate the satisfaction of the family members of the child. Results There was no statistically significant difference in cough symptom scores between the two groups of children before treatment (P>0.05). After 14 days of treatment, there was a statistically significant difference in the scores of the two groups of children compared to before treatment (P<0.05), and the difference between the observation group and the control group after treatment was statistically significant (P<0.05). The time of temperature recovery, breath disappearance and rales disappearance were significantly shorter than the control group, with a statistically significant difference (P<0.05).The nursing satisfaction of the observation group was higher than that of the control group, which the difference was significant (P<0.05). Conclusion Based on traditional Chinese medicine constitution identification, traditional Chinese medicine nursing techniques can improve cough symptoms in children infected with Mycoplasma pneumoniae, accelerate body recovery, and improve intervention effectiveness. It is worth further research.

Effect of Comfort Care in Maternal Care after Cesarean Section

SHEN Jing-lan

2024, 42(14):  103-106. 

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Objective To analyze the effect of comfort care intervention after cesarean section. Methods From May 2022 to May 2023, a total of 60 women admitted to Wuchuan County Hospital of Traditional Chinese Medicine undergoing cesarean section were selected to carry out this clinical practice study, they were grouped by single and even number method, and after surgery, and 30 patients in each group, the observation group and the control group were given comfort nursing and routine nursing intervention, and the depression score, comfort score and nursing satisfaction before and after nursing of the two groups were compared. Results Before nursing, there was no significant difference in maternal depression score and comfort score between the two groups(P>0.05), and after nursing, the maternal depression score in the observation group was lower than that in the control group, the maternal comfort score in the observation group was higher than that in the control group, and the maternal nursing satisfaction in the observation group was higher than that in the control group, and the difference between the two groups was statistically significant(P<0.05). Conclusion The application of comfort nursing intervention after cesarean section can achieve good results, which can not only effectively reduce the negative emotions of women, but also improve their comfort, thereby improving their nursing satisfaction.

The Effect of Acupoint Selection Along Meridians, Vibration and Phlegm Elimination Method Combined with Respiratory Rehabilitation Nursing on Lung Function and Exercise Endurance in COPD Patients

ZHU Xiao-ying

2024, 42(14):  106-109. 

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Objective To explore the effect of vibration phlegm elimination method along meridians combined with respiratory rehabilitation nursing on lung function and exercise endurance in patients with chronic obstructive pulmonary disease (COPD). Methods A total of 80 COPD patients admitted to Heze Traditional Chinese Medicine Hospital from October 2020 to October 2022 were randomly divided into two groups with 40 cases each. The control group received respiratory rehabilitation care, while the observation group received acupoint selection along the meridians and vibration phlegm elimination method combined with respiratory rehabilitation care. Compared two groups of traditional Chinese medicine syndrome scores, lung function [forced vital capacity (FVC), forced expiratory volume in 1 second FEV₁), FEV₁/FVC], exercise endurance [6-minute walking test (6MWT)], sputum output, and quality of life [St. George's Respiratory Questionnaire (SGRQ)]. Results After nursing, the observation group had lower scores of coughing, wheezing, phlegm accumulation, white mucus, and mouth mucus than the control group (P<0.05). After nursing, the FVC, FEV₁, and FEV₁/FVC of the observation group were all higher than those of the control group (P<0.05). After nursing, the observation group had a higher 6MWT and sputum output than the control group (P<0.05). The SGRQ score of the observation group after nursing was lower than that of the control group (P<0.05). Conclusion The combination of acupoint selection, vibration and phlegm elimination along the meridians, and respiratory rehabilitation nursing can significantly reduce clinical symptoms, improve lung function, promote phlegm elimination, and improve exercise endurance and quality of life in COPD patients.

The Application Effect of Traditional Chinese Medicine Scraping Combined with Ear Point Sticking and Pressure Nursing on High Intraocular Pressure Caused by Qi Stagnation and Blood Stasis after Vitrectomy

YU Ming-rui, CUI Ling-ya, XIA Ting-ting, CHEN Qing, WANG Wen-juan

2024, 42(14):  110-113. 

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Objective To explore the application effects of traditional Chinese medicine scraping combined with ear acupoint pressing nursing in the treatment of high intraocular pressure caused by qi stagnation and blood stasis after vitrectomy. Methods A total of 96 patients with intraocular hypertension with qi stagnation and blood stasis after vitrectomy treated in Jiangsu Provincial Hospital of Traditional Chinese Medicine from January 2020 to December 2022 were selected as the study objects, and were divided into observation group (48 cases) and control group (48 cases) according to 1:1 random coin toss principle. The control group was given auricular point sticking care, and the observation group was given traditional Chinese medicine scraping care on the basis of the control group's care. The two groups were observed for 1 month, and the occurrence of IOP, vision, pain and adverse reactions were recorded in the two groups. Results After nursing, the total effective rate of the observation group was significantly higher than the control group (P<0.05). After care, the IOP of both groups was lower than before care, and the optimal naked eye visual acuity was higher than before care (P<0.05), and the IOP of the observation group was lower and the optimal naked eye visual acuity was higher (P<0.05). After nursing, the pain NRS scores in both groups were lower than before nursing (P<0.05), and the decrease in observation group was greater (P<0.05). The incidence of adverse reactions such as insomnia, shoulder, neck and back pain, fatigue and discomfort in the observation group was significantly lower than the control group (P<0.05). Conclusion The application of TCM Gua Sha combined with auricular point sticking nursing in the treatment of high IOP with qi stasis and blood stasis after vitrectomy can promote the reduction of IOP, improve the overall treatment effect, reduce the best naked eye vision, promote pain relief and reduce the incidence of adverse reactions.

Application of Multidisciplinary Intervention Combined with Short-Term Motor Imagery Therapy of Patients with Brain Tumor

CHEN Yuan-yuan, GUAN Dong-dong, ZHU Huai-qin, LIU Wen-bo, ZHANG Yue-hua

2024, 42(14):  113-116. 

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Objective To explore the effect of multidisciplinary intervention combined with short-term motor imagery therapy of patients with brain tumor. Methods A total of 96 patients from January 2020 to October 2023 who were underwent brain tumor surgery the Second People's Hospital of Liaocheng were selected, a randomized double-blind trial was used, and the patients were divided into the intervention group (n=48) and the control group (n=48) by random number table method. The control group was given routine care, and the intervention group was given multidisciplinary intervention combined with short-term motor imagery therapy. The nutritional status, mental state, quality of life (GQOL-74), and complications in both groups were compared. Results One month after surgery, the NUTRIC, MMSE scores in both groups were increased (P<0.05), and in comparision of the control group, the intervention group was higher (P<0.05). One month after surgery, the psychological, physical, and social function scores in both groups were increased (P<0.05), and in comparision of the control group, the intervention group was higher (P<0.05). In comparison of the control group, the incidence of complications in the intervention group was lower (P<0.05). Conclusions hort-term exercise imagination therapy combined with multidisciplinary collaborative intervention can improve nutritional status, mental state, improve quality of life, and reduce the incidence of complications in patients undergoing brain tumor surgery.

Experience in the Treatment of Stagnation

MA Ping, FU You-juan, HE Sheng-cong, LUO Bing, YANG Ting-zhi, HE Wen-qing

2024, 42(14):  163-166. 

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Retention of urine is one of the common diseases of the urinary system in elderly men. According to Chinese medicine, the disease is mainly caused by unclean diet, invasion of external evil, internal stagnation of stagnant toxins, internal injury of emotion and will, and physical weakness and prolonged illness. The location of the disease is mainly in the bladder, and the liver, lungs, kidneys, spleen and Sanjiao are the relevant internal organs. The urine is usually regulated by the Kidney Qi, the Lung Qi, the Liver Qi and the San Jiao, and is also affected by emotions, stasis, phlegm and fear. I have been in clinical practice for many years, and I have concluded in my clinical practice the identification and treatment method of draining heat, promoting the lung and clearing water, strengthening the spleen, tonifying the kidney and resolving dampness, and moving qi and relieving depression to clear the liver, with good results in patients.

The values of fully automated immunocytochemical staining P16/Ki-67 double staining in cervical lesions screening

HU Hong-xia

2024, 42(14):  166-170. 

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Objective To explore and analysis the values of fully automated immunocytochemical staining P16/Ki-67 double staining in cervical lesions screening. Methods From April 2022 to June 2023, 120 cases of patients who underwent cervical lesion screening at Jiagang Hospital were selected as the research subjects. All patients were underwent thinprep cytology test (TCT), pathological examination, and automatic immunocytochemical staining P16/Ki-67 double staining, and were to determine the screening results. Results There were 28 cases were positive for P16/Ki-67 double staining in the 120 cases, with a total positive rate of 23.3%. 67 cases of benign reactive cell changes, 37 cases of atypical squamous epithelial cells with unclear diagnostic significance in the cervix, 12 cases of low-level cervical squamous intraepithelial lesions, 4 cases of high-level cervical squamous intraepithelial lesions. The positive rates of P16/Ki-67 double staining were 16.4%、21.6%、41.6%、100.0%, respectively, with compared were significant differences (P<0.05). Pathological examination determined that 16 cases were normal, 85 cases of cervical intraepithelial neoplasia grade I, 14 cases of cervical intraepithelial neoplasia grade Ⅱ, 4 cases of cervical intraepithelial neoplasia grade Ⅲ, and 1 cases of cervical cancer. The positive rates of P16/Ki-67 double staining were 6.2%、15.3%、71.4%、75.0% and 100.0%, respectively, with compared were significant differences (P<0.05). Using pathological examination results as the gold standard, the sensitivity and specificity of P16/Ki-67 double staining in cervical lesions screening were 73.7%(14/19)and 86.1%(87/101), respectively. Receiver operating characteristic curve analysis showed that the area under the curve of automatic immunocytochemical staining P16/Ki-67 double staining in cervical lesion screening were 0.872, and the Kappa value was 0.824. Conclusion The sensitivity and specificity of P16/Ki-67 double staining in cervical lesions screening and diagnosis are relatively high, and it has good clinical value.

Effect of Rectal Drip of Traditional Chinese Medicine on CoxA16 and EV71 Enterovirus Infection of Hand, Foot and Mouth Disease

MAO Mei, CHEN Bo

2024, 42(14):  170-174. 

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Objective To observe the effect of rectal drip of traditional Chinese medicine on CoxA16 and EV71 enterovirus infection of hand-foot-mouth disease. Methods Selected 85 children with CoxA16, EV71 enterovirus infection in HFMD, Guizhou, General Hospital from August 2019 to August 2022, and divided into observation group (42 cases) and control group (43 cases) according to the method of digital table at any time. The patients in the control group were treated with ribavirin, and the patients in the observation group were treated with rectal drip of traditional Chinese medicine. The scores of oral herpes, fever, rash and other symptoms of the two groups before and after treatment were compared, as well as the inflammatory factors of patients before and after treatment. The level of immune indicators and the incidence of adverse reactions after treatment were compared in both groups and between the two groups. Results There was no statistically significant difference in the scores of oral herpes, fever and rash between the two groups before treatment (P>0.05); IL-6, IL-8, TNF in the two groups before treatment- α The level difference was not statistically significant (P>0.05). After treatment, IL-6, IL-8, TNF in the two groups- α Both of them were decreased, and the above reduction of patients in the observation group was greater than that in the control group after treatment(P<0.05); After treatment, the levels of CD4⁺, CD3⁺ and CD4⁺ / CD8⁺ increased in both groups, and the level of CD8+ decreased, and the change of children in the observation group was greater than that in the control group (P<0.05); The incidence of adverse reactions in the observation group was 4.76%, and that in the control group was 18.60%. The incidence of adverse reactions in the observation group was lower than that in the control group(P<0.05). Conclusion The treatment of rectal drip of traditional Chinese medicine in children with CoxA16 and EV71 enterovirus infection of hand-foot-mouth disease can reduce the clinical symptoms and inflammatory reactions of children, improve the immune function, and have fewer adverse reactions, which is worthy of reference.