Objective Through the Neo4j knowledge graph, explore the "medication" pattern of traditional Chinese medicine in treating ulcerative colitis. Method Retrieve clinical research literature on the treatment of ulcerative colitis with traditional Chinese medicine from the China National Knowledge Infrastructure (CNKI) database from January 1, 2020 to December 1, 2024. Collect data on traditional Chinese medicine prescriptions, syndrome types, combined traditional Chinese medicine operations, and combined Western medicine. Perform statistical analysis on the properties, flavors, meridians, and efficacy of traditional Chinese medicine in the prescription data. Perform frequency, frequency, and weighted frequency statistics on all data. Calculate the weight, confidence, and enhancement of the relationship between traditional Chinese medicine oral formulas, traditional Chinese medicine enema formulas, and traditional Chinese medicine prescriptions themselves. Then import the data into the Neo4j graph database. Result A total of 242 valid data were collected, and the oral Chinese medicines with a frequency of≥50% included Atractylodes macrocephala, Coptis chinensis, and Paeonia lactiflora; The enema herbs with a frequency of ≥50% include Bai Ji and Huang Bai; The only type of syndrome with a frequency of ≥10% is damp heat in the large intestine; Other operations with a frequency of ≥10% include moxibustion, acupuncture, ear acupressure, and acupoint embedding; The only Western medicine with a frequency of ≥10% is mesalazine. After importing the knowledge graph, the relationship between traditional Chinese medicine oral formulas that meet the criteria of frequency ≥10%, confidence ≥65%, improvement≥1, and ranked first in descending order of previously placed word frequency is from Paeonia lactiflora to Atractylodes macrocephala; The relationship between traditional Chinese medicine enema formula and traditional Chinese medicine enema formula is Bai Ji → Huang Bai; The top 5 in terms of meridian frequency are spleen, liver, stomach, lungs, and large intestine; The top 5 in terms of frequency of medicinal properties are cold, warm, flat, cool, and hot; The top 5 medicinal flavors are bitter, sweet, spicy, astringent, and sour; The top 5 efficacy frequencies for splitting are detoxification, clearing heat, relieving pain, drying dampness, and stopping bleeding. Conclusion The analysis using the Neo4j knowledge graph reveals the "pairing drug" patterns in TCM for treating UC. The oral herbs Atractylodes, Peony, and Coptis, along with the enema herbs Bletilla and Phellodendron, were frequently used. The Spleen, Liver, Stomach, and Large Intestine meridians were commonly involved in the treatment process. This study provides a theoretical basis for TCM in the treatment of UC and offers clinical reference for drug selection.

Objective To observe the clinical effect of acupuncture cross pulse and floating needle in hemiplegia patients. Methods A total of 80 patients with stroke hemiplegia lower limb muscle spasm were randomly divided into control group (conventional acupuncture treatment, n=40) and study group (acupuncture cross pulse with floating needle, n=40). To compare the treatment effects between the two groups. Results The clinical efficacy of the study group was higher than that of the control group, and the statistical difference was established (P<0.05).After treatment, the lower limb modified Ashworth spasticity scale score of the study group was lower than that of the control group(P<0.05).And compared with the control group, the WGS score was significantly reduced and the FAC score was significantly improved. Conclusion Cross pulse with floating needle can effectively improve stroke gait and walking ability.

Objective To observe the clinical efficacy of ointment combined with fascial release surgery in the treatment of postpartum low back pain. Methods From September 2021 to June 2023, 60 patients with postpartum low back pain admitted to our hospital were selected as the study subjects and randomly divided into a conventional treatment group and a plaster and fascia group, with 30 cases in each group. Patients in the conventional treatment group mainly receive conventional treatment. Including conventional application of electrical stimulation, biofeedback, and Kegel training methods. The ointment massage+fascia group received additional ointment massage treatment and fascia release surgery on the basis of the conventional treatment group. Both groups were treated for 4 weeks. Follow up on pain levels was conducted before treatment and at 1, 3, and 6 months of treatment, and the degree of lower back pain was evaluated using the Visual Analog Scale (VAS). Simultaneously evaluate pelvic floor muscle strength and organ prolapse staging (POP-Q) before and after treatment. Results In terms of pain, the comparison of VAS between the 2 groups before treatment, the difference was not statistically significant (P>0.05); after 1, 3, and 6 months of treatment, the VAS scores of both groups were lower than those before treatment, and the difference was statistically significant (P<0.05); after 1, 3, and 6 months of treatment, the cream mojo+fascia group was better than that of the conventional treatment group (P<0.05). In terms of pelvic floor muscle strength, the difference between the two groups before treatment was not statistically significant (P>0.05); after 4 weeks of treatment, the pelvic floor muscle strength of both groups was higher than that before treatment, and that of the Paste Mo + Fascia group was higher than that of the conventional treatment group (P<0.05). Comparison of POP-Q staging between the two groups before treatment, the difference was not statistically significant (P>0.05); after 4 weeks of treatment, the POP-Q staging of the two groups was better than before treatment, and the cream massage + fascia group was better than the conventional treatment group (P<0.05). Conclusion The combination of ointment and fascia release surgery can improve the pain score of postpartum low back pain patients, reduce the degree of visceral prolapse, and improve pelvic floor muscle strength, which is worthy of further research.

Objective To explore the effect of combined external application of traditional Chinese medicine on the detumescence nursing of ankle joint fracture before operation based on the concept of accelerated rehabilitation surgery. Methods 78 patients with ankle fracture admitted to our hospital from May 2021 to August 2021 were retrospectively selected and divided into control group (39 cases, received routine detumescence care from May 2021 to June 2021) and experimental group (39 cases, received routine detumescence care from May 2021 to June 2021) according to nursing methods. July 2021 to August 2021 in the control group based on accelerated rehabilitation concept combined with external application of traditional Chinese medicine nursing). Both groups continued nursing until surgery. The two groups of indicators were compared. Results At admission, there was no difference in swelling ratio and swelling degree between two groups (P>0.05). At the time of operation, the swelling ratio of affected limb in the two groups was lower than that at admission, and the experimental group was lower than that in the control group, the difference was statistically significant (P<0.05). During operation, the swelling degree of experimental group was better than that of control group, the difference was statistically significant (P<0.05). At admission, there was no significant difference in numeric rating scales (NRS) scores between the two groups (P>0.05). 36 h after admission, the NRS score of the two groups was lower than that at admission, 12 h after admission, 24 h after admission, 24 h after admission, the NRS score of the two groups was lower than that at admission, 12 h after admission, 12 h after admission, and the NRS score of the two groups was lower than that at admission, the difference was statistically significant (P<0.05). 12 h, 24 h and 36 h after admission, the NRS score of test group was lower than that of control group, and the difference was statistically significant (P<0.05). The pain disappearance time of experimental group was shorter than that of control group, and the difference was statistically significant (P<0.05). During hospitalization, the total incidence of adverse reactions in experimental group was lower than that in control group, and the difference was statistically significant (P<0.05). Conclusion The application of accelerated rehabilitation concept combined with external application of traditional Chinese medicine can reduce the body pain, improve the effect of detumescence, and have good safety.

Zhou Chen's "Hou Sheng Xun Zuan" is one of the Ming Dynasty's works on health preservation.The book comprises six volumes and covers nine topics,offering many simple,easy-to-understand health methods tailored to different demographics.Its discussion on pediatric health methods is particularly comprehensive and detailed,showcasing Zhou Chen's forward-thinking in pediatric health.The article thoroughly reviews and discusses the pediatric health content in "Hou Sheng Xun Zuan" from various aspects including preparation for pregnancy in men and women, the ten-month gestation, neonatal care, children's diet, children's daily life, and early education.It distills the essence of pediatric health from the book, providing a reliable reference and inspiration for contemporary pediatric health care.

Objective To explore the effects of humanistic care combined with motivational interview intervention on psychological state and coping style of patients with chronic heart failure (CHF). Methods A total of 124 CHF patients admitted to Zhongda Hospital Affiliated to Southeast University from January 2022 to December 2022 were selected as the study objects, and they were divided into control group (n=62) and observation group (n=62) by random number table method. The control group received routine humanistic care intervention, and the observation group combined motivational interview intervention on the basis of the control group. To explore the differences of mental state [Depression-Anxiety-Stress Scale (DASS-21)], coping style [SCSQ], mental resilience [Conner-Davidson Resilience Scale (CD-RISC)] and well-being [Campbell Well-being Index Scale (IWB)] between the two groups before intervention and 3 months after intervention. Results After 3 months of intervention, the scores of depression, anxiety and stress in 2 groups were lower than before intervention, and the observation group was lower than the control group (P<0.05). After 3 months of intervention, the positive coping scores in both groups were higher than before intervention, and the negative coping scores were lower than before intervention, and the positive coping scores in the observation group were higher than those in the control group and the negative coping scores were lower than those in the control group (P<0.05). After 3 months of intervention, the scores of resilience, self-reliance, optimism, the average score of general emotion index and the score of life satisfaction questionnaire in 2 groups were higher than before intervention, and the observation group was higher than the control group (P<0.05). Conclusion The combination of humanistic care and motivational interview intervention can significantly improve the psychological state and resilience of CHF patients, make them face the stress more actively, and enhance their happiness.

Objective To analyze the diagnostic value of hemoglobin a_1c (HbA_1c), hemorheology index and coagulation index in type 2 diabetes mellitus (T2MD) patients with microangiopathopathy. Methods 200 patients with type 2 diabetes admitted to Rizhao Maternal and Child Health Hospital from April 2023 to April 2024 were divided into control group (n=110) and microangiopathopathy group (n=90) according to whether they had microangiopathopathy. HbA_1c, plasma viscosity(PV), whole blood viscosity, erythrocyte sedimentation rate (ESR), mean platelet volume (MPV) and platelet distribution width (PDW) were compared between the two groups. The risk factors of microangiopathopathy in T2MD patients were analyzed, and the receiver operating characteristic curve (ROC) was plotted, and the area under the curve (AUC) was used to evaluate the diagnostic value. Results HbA_1c, PV, whole blood high tangential viscosity, whole blood low tangential viscosity, ESR, FIB, MPV and PDW in microvascular disease group were higher than those in control group, the difference was statistically significant (P<0.05). Logistic regression analysis showed that HbA_1c, PV, whole blood low tangency viscosity and FIB were all risk factors for the complication of microangionopathy in T2MD patients(P<0.05). The AUC values of HbA_1c, PV, whole blood low tangency viscosity, FIB and the combination of HBA_1c and PV were 0.799, 0.802, 0.841, 0.797, 0.907, respectively (P<0.05), and the AUC values of the combination of HBA_1c and PV were higher(P<0.05). Conclusion HbA_1c, PV, whole blood low tangential viscosity and FIB are the risk factors for T2MD complicated with microangularity, and the combination of the four factors is more helpful for the diagnosis of T2MD complicated with microangularity.

Objective To investigate and analyze the application effectiveness of prevention and disinfection control in infectious disease outbreaks of public health emergencies. Methods The public health data of 400 different public places (1 342 people surveyed) in Rizhao City, Shandong Province from February 2020 to January 2024 were retrospectively analyzed, and were divided into control group and observation group according to different methods of infectious disease prevention,disinfection control and time.The control group (from February 2020 to April 2022, 198 public places involved, 687 surveyed members of the public) adopted basic infectious disease prevention and disinfection control methods, while the observation group (from May 2022 to January 2024, 1 public places involved 202, 655 members of the public surveyed adopted comprehensive infectious disease prevention and disinfection control methods.The knowledge of prevention and disinfection control of infectious diseases,evaluation index of disinfection effect, incidence of infectious diseases, response time of infectious disease outbreak and success rate of tracing infectious source were compared between the two groups of public. Results The scores of knowledge of infectious diseases,disinfection control knowledge, personal protection knowledge,cognition of disinfection control measures in public places, and mastery of infectious disease outbreak knowledge in the observation group were higher than control group, with statistical significance (P<0.05). The average disinfection time of the observation group was longer than control group, and the average disinfection range of the observation group was higher than control group, with statistical significance (P<0.05). The undetected rate of surface microorganisms in the observation group was higher than control group, and the difference was statistically significant (P<0.05).The incidence of infectious diseases in the observation group was lower than control group,the response time of infectious disease outbreak in the observation group was longer than control group,and the success rate of tracing infection source in the observation group was higher control group,the difference was statistically significant(P<0.05). Conclusion The application of comprehensive infectious disease prevention and disinfection control methods can significantly enhance the public's understanding of infectious disease prevention and disinfection control,obtain better disinfection effectiveness evaluation indicators, as well as reduce the incidence rate of infectious diseases,shorten the response time to infectious disease outbreaks, and increase the success rate of infectious source tracking.

Objective To investigate the expression of cytological examination and tumor markers in patients with lung cancer accompanied by pleural effusion, and their clinical significance, to provide a basis for the diagnosis of malignant tumors. Methods A total of 90 patients with lung tumors accompanied by pleural effusion who were treated at Taian Cancer Prevention and Treatment Hospital from June 2018 to June 2023 were selected for this study. All patients underwent cytological examination and tests for carcinoembryonic antigen (CEA), carbohydrate antigen 125 (CA125), carbohydrate antigen 19-9 (CA19-9), and neuron-specific enolase (NSE). According to the gold standard of pathological examination through surgery or biopsy, the 90 patients were divided into a benign lung tumor group(48 cases) and a lung cancer group (42 cases). The cytological detection rates, levels of tumor markers, and positive expression rates were compared between the two groups. The diagnostic efficacy of cytological examination of pleural effusion,tumor markers, and combined detection for malignant pleural effusion was compared using ROC curves. Results In the lung cancer group, the levels of CEA, CA19-9, NSE, and CA125 in pleural effusion were significantly higher than those in the benign lung tumor group,and the difference was statistically significant (P<0.05). All 90 patients with tumor-associated pleural effusion underwent cytological examination; among the lung cancer patients, tumor cells were detected in 32 out of 42 cases (76.19%), with 22 diagnosed upon the first submission and 10 diagnosed after two or more submissions, while the remaining 10 cases did not show tumor cells. No tumor cells were detected in the 48 patients with benign lesions. The combined detection showed the highest diagnostic value (area under the curve [AUC]=0.889), followed by tumor marker detection (AUC=0.767) and cytological detection (AUC=0.881)(P<0.05). Conclusion The combination of cytological examination and tumor markers in pleural effusion is more beneficial for the diagnosis of patients with lung cancer accompanied by pleural effusion.