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Table of Content

    22 July 2024, Volume 42 Issue 15
    Previous Issue    Next Issue
    Clinical Observation on the Adjunctive Treatment of Colonic Cancer Ascites (Spleen Kidney Yang Deficiency Syndrome) with Huolong Cupping Tongyin Sanyang Moxibustion
    NIE Cheng-mei, MIN Jing-jing, FENG Yuan-yuan
    2024, 42(15):  1-4. 
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    Objective To explore the effect of Huolong Can Tongyin Sanyang Moxibustion on the treatment of spleen kidney yang deficiency syndrome in colon cancer ascites, and provide reference for auxiliary treatment of colon cancer ascites. Methods Collect clinical data of 66 patients with colon cancer ascites and spleen kidney yang deficiency syndrome who received inpatient treatment in the Suizhou Traditional Chinese Medicine Hospital Affiliated with Hubei University of Chinese Medicine from April 2023 to October 2023. According to different treatment methods, 33 cases in the control group received moxibustion treatment, while 33 cases in the observation group received Huolong cupping therapy for clearing yin and three yang. Compare the changes in 24-hour urine volume, body weight, abdominal circumference, ascites regression grade, and traditional Chinese medicine syndrome scores between the two groups after 2 weeks of treatment. Results After treatment, the observation group showed an increase in 24-hour urine output, weight loss, decreased abdominal circumference, decreased grading of ascites regression, and decreased traditional Chinese medicine syndrome scores, with statistically significant differences (P<0.05). Conclusion The auxiliary treatment of colon cancer ascites with spleen and kidney yang deficiency syndrome using Huolong cupping and three yang moxibustion method has the characteristics of safety, significant efficacy, and fewer adverse reactions, which is worth applying in clinical practice.
    Effect Analysis of Wandai Decoction Combined with Focused Ultrasound in the Treatment of Cervical Intraepithelial Neoplasia of Spleen Dampness
    YANG Sheng-nan, CAI Ying-xing, LI Yu-juan, LU Xiu-hua, DU Rui-chao, YAN Hua
    2024, 42(15):  5-8. 
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    Objective To investigate and observe the therapeuticeffect of Wandai decoction combined with focused trasound in patients with cervical intraepithelial neoplasia and influence for body immune. Methods A total of 60 patients diagnosed with cervical intraepithelial neoplasia by cervical biopsy in Linyi Central Hospital from June 2021 to May 2022 were selected and randomly divided into control group (30 cases) and trial group (30 cases). The control group was treated with Haifu high-intensity focused ultrasound alone, and the trial group was treated with Wandai decoction combined with Haifu high-intensity focused ultrasound. After treatment, the curative effect, the negative conversion rates of human papillomavirus(HPV),TCM syndrome score, CD4+T, CD8+T, CD4+T/CD8+T were analyzed.the main symptoms scoreof TCM syndrome , the secondary symptoms scoreof TCM syndrome , and the blood immunological indexes (CD4+T, CD4+T, CD4+T/CD8+T) were analyzed. Results The curative effect in the experimental group was higher than that in the control group (P>0.05). After treatment, the D-value of Reid’s Colposcopy index in the trial group was higher than that in the control group (P<0.05), and the negative conversion rate of HPV in the trial group was higher than that in the control group at 3 months (P>0.05), After treatment, the scores of TCM syndromes in both groups were lower than those before treatment (P<0.05). and the scores of secondary symptoms in the experimental group were lower than those in the control group (P>0.05). After treatment, the lymphocyte ratio of CD4+T and CD4+T/CD8+T in both groups were significantly improved, and the experimental group was superior to the control group (P<0.05). Conclusion Wandai decoction combined with high intensity focused ultrasound has a better therapeutic effect on CIN patients, which can improve the TCM syndromes and balance the immune status of the patients, it is worthy of clinical application.
    Efficacy of Hand Function Assessment and Training System Combined with Transcranial Direct Current Stimulation on Upper Limb and Hand Dysfunction in Stroke Patients
    SHI Fang, HUANG Fu-biao
    2024, 42(15):  8-12. 
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    Objective To observe the efficacy of hand function assessment and training system combined with transcranial direct current stimulation (tDCS) on upper limb and hand dysfunction in stroke patients. Methods A total of 110 elderly stroke patients with upper limb and hand dysfunction in China Rehabilitation Research Center were included from October 2021 to October 2023. According to the random number table method, they were divided into control group (tDCS treatment) and observation group (hand function assessment and training system combined with tDCS treatment), with 55 cases in each group. Both groups underwent routine stroke rehabilitation training. The recovery status of upper limb and hand function [hand Brunnstrom grading, Action Research Arm Test (ARAT)], upper limb motor ability [Fugl-Meyer Assessment of Upper Extremity (FMA-UE), Wolf Motor Function Test (WMFT)], surface electromyography signal and quality of life [Activity of Daily Living Scale (ADL), National Institutes of Health Stroke Scale (NIHSS)] were compared before and after treatment. Results After treatment, the Brunnstrom and ARAT were significantly increased in both groups (P<0.05), and the two indicators in observation group were significantly higher than those in control group (P<0.05). The FMA-UE score and WMFT score in both groups were significantly enhanced after treatment (P<0.05), and the observation group had significantly higher scores (P<0.05). After treatment, the RMS values of Flexor carpi radialis flexor wrist and Extensor carpi radialis extensor wrist in the two groups were significantly improved (P<0.05), and the RMS values were significantly higher in observation group than those in control group (P<0.05). After treatment, the ADL score in the two groups was significantly risen (P<0.05) while the NIHSS score was significantly reduced (P<0.05). The ADL score in observation group was significantly higher (P<0.05) while the NIHSS score was significantly lower compared to control group (P<0.05). Conclusion Hand function assessment and training system combined with tDCS can effectively improve the upper limb and hand function of stroke patients, strengthen the electromyography signal and enhance the quality of life.
    Clinical Study on the Efficacy of Xiaozhui Mixture on Postoperative Defecation Function after Rectal Cancer Surgery
    WANG Zhen-bo, FENG Wei, ZHAO Ri-zhi, ZHANG Peng-fei
    2024, 42(15):  12-15. 
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    Objective To investigate the effect of Xiaozhui mixture on improving postoperative defecation function of rectal cancer. Methods A total of 60 patients who received laparoscopic radical resection of rectal cancer in the Gastrointestinal Surgery Department of Rizhao Hospital of Traditional Chinese Medicine from February 2020 to June 2022 and met the inclusion criteria were selected and divided into two groups by random number table method, with 30 cases in each group. The control group was instructed to perform bowel function exercise. The observation group performed defecation function exercise, and was given the traditional Chinese medicine Xiaozhui mixture orally, 50m1 each time, twice a day, orally after meals, for 15 consecutive days as a course of treatment, half a month of rest for the next course of treatment, 3 courses of continuous application. The defecation function scores and the levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were compared between the two groups before treatment, 1 month after treatment, 3 months after treatment and 5 months after treatment; Results There were no significant differences in baseline characteristics (gender, age, height and pathological stage) between the two groups (P>0.05). There was no significant difference in AST and ALT between the two groups before and after treatment (1, 3, 5 months)(P>0.05);The defecation score of the observation group was significantly different from that of the control group 1 month and 3 months after treatment , there was statistical significance (P<0.05), but there was no statistically significant difference between the two groups 5 months after treatment (P>0.05). Conclusion The traditional Chinese medicine Xiaozhui mixture can obviously improve the postoperative defecation dysfunction, and the safety is good, worthy of clinical application.
    Efficacy and Effect of Banxia Houpu Decoction Combined with Oxygen Therapy on Senile Pulmonary Heart Disease and Myocardial Function
    WANG Wen-yan, CAO Xue-min
    2024, 42(15):  19-22. 
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    Objective To investigate the effect of Banxia Houpu Decoction combined with oxygen therapy on senile pulmonary heart disease and the effect on myocardial function. Methods A total of 80 elderly patients with pulmonary heart disease in stable stage from July 2021 to March 2023 were selected as research objects.Randomized number table method was used to divide 40 cases into two groups, the control group was given oxygen therapy, the study group was given Banxia Houpu decoction combined with oxygen therapy. Chinese medicine symptom score was evaluated before and after treatment, arterial blood gas analysis, lung function, echocardiography and serum brain natriuretic peptide (BNP) level were detected, and the number of acute exacerbations within 3 months were recorded. Results After treatment, only mPAP in the two groups showed a significant decrease in echocardiography (P<0.05), while other indicators showed no significant changes (P>0.05). The mPAP in the study group was significantly lower than that in the control group (P<0.05); The serum BNP levels in both groups decreased significantly (P<0.05), and the study group was significantly lower than the control group (P<0.05); Both groups showed varying degrees of improvement in lung function, with FEV1 and FEV1/FVC significantly higher in the study group than in the control group (P<0.05); Both groups showed significant improvement in arterial blood gas indicators (P<0.05). The levels of PaO2 in the study group were significantly higher than those in the control group, while PaCO2 was significantly lower than those in the control group (P<0.05); The number of acute exacerbations in the study group was significantly lower than that in the control group (P<0.05). Conclusion Banxia Houpu Decoction combined with oxygen therapy can effectively improve arterial blood gas analysis, reduce pulmonary hypertension, decrease serum BNP level, improve lung function to a certain extent, and help reduce the risk of acute exacerbation in elderly patients with pulmonary heart disease in remission.
    Application Effect of Modified Ginseng Schisandra Decoction Combined with Infantile Massage Method of Regulating Lung and Activating Spleen on Children's Cough with Lung and Spleen Qi Deficiency Syndrome
    SHU Xiu-jin, XU Qing-ling, JIANG Zhou-wei, JI Ting, WA Yang, XU Ting, ZHAO Wei, CHENG Yao, LI Feng-yao
    2024, 42(15):  26-29. 
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    Objective To explore the application effect of Ginseng Schisandra Chinensis Decoction plus lung and spleen regulating infantile massage on children with cough, lung and spleen deficiency syndrome. Methods A total of 80 cases of patients with lung temper deficiency and cough admitted from June 2021 to June 2023 were selected as research subjects, and all children were divided into observation group and control group by lottery method, with 40 cases in each group. Control group to take conventional western medicine treatment, observation group of children on the basis of conventional western medicine treatment increase of ginseng joint lung spleen massage treatment, compare two groups of children with clinical curative effect, before and after treatment of TCM syndrome integral and inflammation factor level change, and compare the two groups of children in the process of treatment of adverse reactions. Results The total response rate of the observation group was significantly higher than that of the control group (P<0.05); There was no significant difference in the comparison of the two groups before treatment (P>0.05), After treatment, the score level of TCM syndrome in both groups was decreased, And the observation group was lower than the control group (P <0.05); TNF-α, CRP and IL-6 between the two groups before treatment (P>0.05), After treatment, TNF-α, CRP-and IL-6, And the observation group was lower than the control group (P<0.05); Neither group had significant adverse effects, There was no significant difference in the comparison of adverse effects(P>0.05). Conclusion The addition and subtraction of Ginseng Schisandra Chinensis Decoction combined with lung and spleen regulating infantile massage can improve the clinical efficacy of children with cough of lung spleen deficiency syndrome, alleviate clinical symptoms, reduce the level of inflammatory reaction of the body, and has high safety.
    The Application Effect of Warm Acupuncture at Trigger Points Combined with Buyang Huanwu Decoction on Hemiplegia after Stroke and Its Effect on Neurological Function
    LIU Shao-juan
    2024, 42(15):  33-36. 
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    Objective To explore the effect of warm acupuncture and moxibustion on stroke and its effect on hemiplegia after stroke. Methods A total of 78 patients with post-stroke hemiplegia admitted to Hanbin District Traditional Chinese Medicine Hospital from April 2021 to April 2023 were selected and divided into an observation group and a control group using a lottery method, with 39 patients in each group. The control group was treated with Buyang Huanwu Decoction. On the basis of the control group, the observation group was treated with warm acupuncture and moxibustion at the pain trigger point. The two groups of patients were compared with each other in terms of clinical treatment effects, levels of inflammatory factors, neurological function, daily living ability and motor function before and after treatment. Results Compared with the matched group, the total effective rate of the observation group was higher (P<0.05); compared with the pre-treatment, the levels of IL-6, IL-2 and TNF-α were lower in the two groups after treatment, and the observation group was lower than the matched group (P<0.05); compared with the pre-treatment, the patients in the two groups had lower NIHSS scores, and the MMSE scores were elevated, and the NIHSS scores of the observation group were lower after treatment and the MMSE scores were higher (P<0.05); compared with before treatment, FMA and MBI scores were elevated in both groups after treatment, and higher in the observation group than in the matched group after treatment (P<0.05). Conclusion The application effect of warm acupuncture and moxibustion on hemiplegia after stroke is significant, which can reduce the level of inflammatory factors in the body, promote the recovery of nerve function, and improve the motor function and daily living ability.
    Pathogen Detection and Epidemiological Analysis of Community-acquired Viral Pneumonia in Children in Midong District, Urumqi
    MAO Jing-fang
    2024, 42(15):  47-51. 
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    Objective To explore and analysisg the pathogen screening and epidemiological situation of children with community-acquired viral pneumonia in Midong District of Urumqi, to provide reference for preventing the occurrence of community-acquired viral pneumonia. Methods From March 2023 to May 2023,90 cases of community-acquired viral pneumonia treated in Midong District People's Hospital were selected as the subjects of this research. Nasopharyngeal swab of all children were collected, and the pathogen status were detected by the multi pathogen Nucleic acid test technology. The general data of children were investigated and compared. Results There were 6 cases were positive for influenza virus type A, 22 cases were influenza virus type B, 2 cases were parainfluenza virus type 1, 1 case was parainfluenza virus type 2, 25 cases were Rhinovirus, 15 cases were respiratory syncytial virus, 10 cases were adenovirus, 3 cases were Human metapneumovirus, and 6 cases were Bocaparvovirus. There were 9 cases of mixed infection were detected, accounted for 10.0%, included 7 cases of mixed infection with two viruses and 2 cases of mixed infection with three viruses. There was no significant difference in the distribution of multi pathogenic Nucleic acid test detection compared between different sexes (P>0.05). The detection rate of Rhinovirus and influenza virus type B in the 1-year-old population were significantly higher than that in other age groups (P<0.05); The detection rate of influenza virus type B in winter were significantly higher than other seasons, and there were no significant difference in the distribution of other viruses compared among in different seasons and age groups (P>0.05). Conclusion The pathogens of children with community-acquired Viral pneumonia in a certain area are mainly Rhinovirus, influenza virus type B, respiratory syncytial virus and adenovirus in Midong District, Urumqi, which can be manifested as mixed infection. Age and season are closely related to the occurrence of Rhinovirus and influenza virus type B.
    Correlation Between Serum Thyroid Hormones Level and eGFR in Patients with Chronic Renal Failure
    XIE Mou-jin
    2024, 42(15):  54-57. 
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    Objective To explore and analysis the correlation between serum Thyroid hormones level and glomerular filtration rate (eGFR) in patients with chronic renal failure. Methods From February 2020 to July 2022, 50 cases of chronic renal failure patients who were diagnosed and treated in the Department of Nephrology and Rheumatology of Guizhou Aerospace Hospital were selected as the chronic renal failure group. And 42 cases of normal people who went to Guizhou Aerospace Hospital for physical examination in the same period were selected as the control group. The serum total thyroxine （TT4）, serum total triiodothyronine （TT3）, and serum free triiodothyronine （FT3） levels were detected in the two groups of patients, and the renal function indexes such as glomerular filtration rate were also determined for comparison. Pearson correlation analysis and multifactor logistic regression analysis were also performed. Results The levels of serum TT4、TT3、FT3 in the Chronic renal failure group were significantly lower than those in the control group (P<0.05). The glomerular filtration rate in the Chronic renal failure group were significantly lower than that in the control group (P<0.05), and the content of serum Blood urea nitrogen and serum creatinine were also significantly higher than that in the control group (P<0.05). In the Chronic renal failure group, Pearson correlation analysis showed that glomerular filtration rate were correlated with serum TT4、TT3、FT3 (P<0.05). Multivariate logistic regression analysis showed that serum TT4、TT3、FT3 were important risk factors affecting glomerular filtration rate (P<0.05). Conclusion The patients with chronic renal failure are mostly accompanied by the decrease of serum TT4、TT3、FT3 and the glomerular filtration rate. The serum Thyroid hormones level is correlated with the glomerular filtration rate.
    Application of Traditional Chinese Medicine Therapies in Cancer Recovery
    JI Rui, LIU Hao-ran, XIAO Wei, CHEN Qian-feng
    2024, 42(15):  69-72. 
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    The basic theory of traditional Chinese medicine in the treatment of tumors plays an important role in the prevention and treatment of tumors, and it is widely used. Traditional Chinese medicine characteristic therapy has achieved remarkable results in tumor rehabilitation, and there are a large number of clinical cases to support it. The combination of traditional Chinese and western medicine in the treatment of tumors has also attracted much attention, and the complementarity and integration of traditional Chinese medicine and modern medicine have been recognized. Related research and clinical trials have a positive evaluation of traditional Chinese medicine in tumor rehabilitation, and believe that traditional Chinese medicine has important value and potential in tumor rehabilitation. Although modern medicine has made progress in tumor treatment, the characteristic therapy of traditional Chinese medicine still plays an irreplaceable role in tumor rehabilitation.
    Research Progress on Homogeneous Nursing in the Management of Chronic Wound Patients
    PENG Xian-qi, XIE Lin-jun, LI Yang, XU Li-li, ZHONG Li
    2024, 42(15):  73-76. 
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    Chronic wound management has been a challenging topic in today's healthcare landscape. The complexity of chronic wounds and the ongoing need for treatment make their effective management an urgent issue. By analyzing the current situation of chronic wound management and the application of homogeneous nursing in chronic wound management, the impact of homogeneous nursing on chronic wound patients was discussed, so as to provide a theoretical basis for further improving the treatment effect and quality of life of chronic wound patients.
    Based on the Practice of Clinical Teaching in Intensive Care Unit, the Shortcomings and Improvement Strategies of "Teaching" and "Learning" are Discussed
    CHENG Ling, GAO Zhi-ling, NIE Wei-qun, LIN Yan-lin, LI Wei, CHEN Yun
    2024, 42(15):  77-79. 
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    Clinical teaching in intensive care unit is an important part of clinical practice for Chinese medical students, and it is also a necessary stage for the training of emergency and critical care medical reserve talents. The author sorted out the shortcomings of "teaching" and "learning" in the clinical teaching practice of the intensive care unit in the hospital, and put forward some improvement strategies. In order to improve the clinical teaching and teaching level of critical care medicine specialty in the hospital, and train high-quality emergency and critical care medicine reserve talents.
    Application of Surgical Room Insulation Mursing Combined With Mindfulness Decompression in Patients Undergoing Laparoscopic Total Hysterectomy
    GUAN Dong-dong, CHEN Yuan-yuan, ZHANG Yan, ZHANG Xing-yue
    2024, 42(15):  88-92. 
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    Objective To explore the effect of surgical room insulation nursing combined with mindfulness decompression intervention on patients undergoing laparoscopic total hysterectomy. Methods A total of 102 patients undergoing laparoscopic total hysterectomy from June 2020 to June 2023 who were admitted in the Second People's Hospital of Liaocheng City were selected, and divided into the intervention group (n=51) and the control group (n=51) by random number table method. The control group was given routine nursing intervention, and the intervention group was given operating room insulation nursing combined with mindfulness decompression intervention. The temperature, anesthesia recovery indicators, mindfulness level, and adverse reactions in both groups were compared. Results There was no statistically significant difference in postoperative body temperature in the control group compared to the preoperative (P>0.05). The body temperature at 30 minutes and 1 hour during surgery was decreased compared to the preoperative (P<0.05). There was no statistically significant difference in intraoperative, 1 hour, and postoperative body temperature between the intervention group compared to the preoperative (P>0.05). In comparision of the control group, the body temperature at 30 minutes and 1 hour of the intervention group was higher (P<0.05). In comparision of the control group, the time for spontaneous breathing recovery, anesthesia resuscitation, and complete awakening of the intervention group was shorter (P<0.05). After intervention, the MAAS scores in both groups were increased (P<0.05), and in comparision of the control group, the intervention group was higher (P<0.05). The incidence of adverse reactions of the intervention group was lower than the control group (P<0.05). Conclusion The combination of surgical room insulation care and mindfulness decompression intervention has a relatively small impact on body temperature in patients undergoing laparoscopic total hysterectomy. It can effectively promote patient recovery, improve their mindfulness level, and reduce adverse reactions.
    Experience in the Treatment of Insomnia Using the "Transcranial Repetitive Stimulation" Method
    YANG-Wan-qing, ZHANG Chun-fang, SHI Jian, ZHANG Yu-mei
    2024, 42(15):  158-161. 
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    "Transcranial repetitive stimulation" acupuncture is a head acupuncture technique performed under the premise of selecting acupoints on the head acupuncture points combined with brain nerve positioning in traditional Chinese medicine, emphasizing the selection of parts and the effectiveness of the manipulation. This article summarizes the experience of using "transcranial repetitive stimulation" acupuncture in the treatment of insomnia, and believes that this pathogenesis is "heart disturbance, yin and yang disorder". With the basic rule of "calming the mind and balancing yin and yang", the yin and yang are adjusted according to the syndrome attributes, so that the body returns to the "yin and yang secret". Emphasizing the use of "transcranial repetitive stimulation" method to puncture the emotional area of the head (frontal area), the left and right Shencong, and the Baihui to replenish the brain and calm the nerves, and cooperate with the Shenmen, Neiguan to nourish the heart and calm the mind, Zhaohai, Shen pulse and adjust yin and yang, the upper, middle and lower three parts of the overall treatment, and at the same time dialectically combined with other body acupuncture points, the clinical effect is remarkable.
    Analysis of Curative Effect of Pre Assembled Hydrophobic Acrylic Intraocular Lens and Coaxial Micro Incision on Age-related Cataract
    LU Yong-jun, JIN Li-hong
    2024, 42(15):  165-168. 
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    Objective To explore and analysis the effects of pre assembled hydrophobic acrylic intraocular lenses and coaxial micro incisions on age-related cataracts. Methods 80 age-related cataract patients diagnosed in Lantian Huayang Eye Hospital from August 2020 to May 2023 were selected as the study subjects and divided into control group and study group according to the random number table method, with 40 cases in each group. All operations were performed by the same physician, and pre assembled hydrophobic acrylic intraocular lenses were implanted. The study group underwent 2.2mm coaxial clear corneal tunnel microincision, and the control group underwent 3.0 mm clear corneal tunnel incision. Recorded the optimal correction, complications, corneal astigmatism, and changes in anterior chamber depth between the study group and the control group. Results The optimal corrected visual acuity of the study group at 1 week and 1 month after surgery were higher than that of the control group (P<0.05), and the highest corrected visual acuity of the study group and the control group at 1 month after surgery showed a statistically significant increase compared to 1 week after surgery (P<0.05). The incidence of complications such as corneal edema, endophthalmitis, lens opacity, and capsule damage in the study group were 7.50% one month after surgery, compared to 25.00% in the control group. The incidence of complications in the study group one month after surgery were significantly lower than that in the control group (P<0.05). The corneal astigmatism of the study group were lower than that of the control group at 1 week and 1 month after surgery (P<0.05), and there were a statistically significant decrease in corneal astigmatism at 1 month after surgery compared to the control group (P<0.05). The anterior chamber depth of the study group were higher than that of the control group at 1 week and 1 month after surgery (P<0.05), and there were no statistically significant difference between the study group and the control group at 1 month and 1 week after surgery (P>0.05). Conclusion The application of pre assembled hydrophobic acrylic intraocular lens combined with coaxial micro-incision in patients with age-related cataract will not affect the depth of the patient's anterior chamber, and can reduce the corneal astigmatism, improve the postoperative vision of the patient, and reduce the incidence of complications.
    Clinical Application Value of CEA, CA125 and CA153 in Diagnosis of Lung Cancer
    ZHOU Meng-jiao
    2024, 42(15):  172-175. 
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    Objective To study the clinical value of serum carcinoembryonic antigen (CEA), carbohydrate antigen 125(CA125) and carbohydrate antigen 153(CA153) in the diagnosis of lung cancer. Methods From March 2018 to March 2023, 96 patients with highly suspected lung cancer in Jiangyin Fifth People's Hospital were taken as the research object. Serum CEA, CA125 and CA153 levels of all patients were measured at the time of admission,and the consistency between the diagnosis results of CEA, CA125 and CA153 for lung cancer and the gold standard was analyzed with pathological results as the gold standard. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of CEA, CA125 and CA153 in the diagnosis of lung cancer were calculated, and the diagnostic efficacy of CEA,CA125 and CA153 in the diagnosis of lung cancer was analyzed by using the receiver's working curve (ROC). Results Among 98 highly suspected lung adenocarcinoma patients, 80 were positive and 18 were negative. The consistency between the combined detection of lung adenocarcinoma and the gold standard is higher than that of CEA, CA125, and CA153 alone. The sensitivity,accuracy and negative predictive value of combined detection in the diagnosis of lung cancer were significantly higher than those of CEA, CA125 and CA153 alone (P<0.05), while the specificity and positive predictive value were not significantly different from those of CEA, CA125 and CA153 alone (P>0.05). ROC curve shows that the combined detection has higher accuracy for lung cancer than CEA, CA125 and CA153 alone. Conclusion CEA, CA125 and CA153 have good diagnostic value for lung cancer, and their combined use can effectively improve the diagnostic efficiency and have high application value.
    Construction and Application of An Intelligent Reproductive Health Management Model for Women of Childbearing Age in Yulin Area
    ZHONG Lei, DU Yun-xia
    2024, 42(15):  175-178. 
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    Objective To explore and analysis the construction and application effect of an intelligent reproductive health management model for women of childbearing age in Yulin area. Methods Used stratified, phased, and probability sampling methods,350 cases of women of childbearing age who underwent reproductive health management at Yulin Maternal and Child Health Hospital in Yulin region were selected as the control group from September 2019 to April 2021, and the other 350 cases of women of childbearing age who underwent reproductive health management at Yulin Maternal and Child Health Hospital were selected as the intelligent group from May 2021 to January 2023.The control group were received routine reproductive health management,while the intelligent group were received intelligent reproductive health management.The follow-up time for reproductive health management in both groups was 6 months. Results The followed-up compliance of the intelligent group during the 6-month management period were 98.57%, while the control group were 88.89%. The intelligent group showed a statistically significant increase compared to the control group (P<0.05).The execution rates of healthy behaviors such as maintaining menstrual hygiene, daily external genital cleaning, and daily underwear replacement during the 6-month period managed by the intelligent group were 98.57%, 97.14%, and 94.57%, which showed there were significant improvement compared to the 87.14%, 88.29%, and 82.00% of the control group (P<0.05). There was a significant increase in the knowledge score of the individual items of reproductive health management knowledge in the smart group after 6 months of management compared to the control group (P<0.05). After 6 months of management, the satisfaction rate with reproductive health management in the intelligent group were 99.14%, compared to 92.86% in the control group that there were statistically significant increase in the intelligent group compared to the control group (P<0.05). Conclusion The construction and application of an intelligent reproductive health management model for women of childbearing age in Yulin region can improve follow-up compliance, as well as improve the implementation rate and knowledge awareness rate of health behaviors, thereby improving the satisfaction of reproductive health management.
    Effect of Plasma Homocysteine on Blood Pressure and Cardiovascular Events in Patients with Acute ST-segment Elevation Myocardial Infarction
    XIN Lin-ze, ZHANG Yi-ming, GAO Zong-peng, HUANG Jian-ying, XU Yao
    2024, 42(15):  179-183. 
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    Objective To investigate the effect of plasma homocysteine (Hcy) on Central arterial pressure (CAP) and major adverse cardiovascular events (MACE) in patients with acute ST-segment elevation myocardial infarction (STEMI). Methods A total of 122 patients with STEMI who received emergency percutaneous coronary intervention (PCI) were divided into normal Hcy group (Hcy<15 μmol/L, n=80) and high Hcy group (Hcy≥15 μmol/L, n=42) according to plasma Hcy level, and the clinical data of the two groups were compared. The Kaplan-Meier method was used to plot the survival curve of patients and compare the effects of different factors on MACE in STEMI patients. Cox regression analysis was used to explore the risk factors for MACE in STEMI patients. Results The proportion of hypertension, central arterial systolic blood pressure (CASP) and brachial artery systolic blood pressure (SBP) were higher in the high Hcy group than in the normal Hcy group (P<0.05). Pearson correlation analysis showed that plasma Hcy was positively correlated with CASP, SBP and brachial artery diastolic blood pressure (DBP) (P<0.05). Kaplan-Meier survival curve analysis showed that patients with CAPP≥51.5 mm Hg, PP≥52 mm Hg, smoking and degree of lesions had an increased risk of MACE (P<0.05). Multivariate Cox regression analysis showed that smoking and PP were independent risk factors for MACE in patients with STEMI (P<0.05). Conclusion Plasma Hcy is closely related to blood pressure levels, smoking and PP are independent risk factors for MACE in STEMI patients.
    The Significance of PCT, CRP and Blood Lipid in the Examination of Hemolytic Jaundice in Neonates
    SHI Jun-hong
    2024, 42(15):  183-186. 
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    Objective To analyze the significance of procalcitonin (PCT), C-reactive protein (CRP) and blood lipid indexes in neonatal hemolytic jaundice. Methods Selection of shaanxi province transportation hospital in July 2021-May 2023,73 cases of newborns hemolytic jaundice as the study object, as the observation group, extract the same period in shaanxi province transportation hospital examination of healthy newborn 73 cases for the control group, all detection PCT,CRP and lipid index, analysis of the application of above indicators in newborns with hemolytic jaundice and neonatal infection rate. Results Platelets of newborns in the experimental group, red blood cells lower than the control group, both showed significant differences, the contrast difference was statistically significant (P<0.05). The levels of PCT and CRP in the experimental group were higher than those in the control group, with significant differences, the contrast difference was statistically significant (P<0.05). The total bilirubin, cholesterol, and triglycerides in the experimental group were significantly higher than those in the control group, with significant differences, the contrast difference was statistically significant (P<0.05). The infection rate in the observation group was higher than the control group, and the difference was significant (P<0.05). Conclusion The detection level of CRP and PCT in newborns hemolytic jaundice is significantly increased, which can help clinicians understand the progress of the newborns, guide timely and effective clinical treatment and nursing measures, and is of great significance to promote the early rehabilitation of newborns.
    The Effect of Corneal Contact Lens Application on Visual Quality after Pterygium Resection Surgery
    XIE Xiao-fang
    2024, 42(15):  193-196. 
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    Objective To explore and analysis the impact of corneal contact lenses on visual quality after pterygium resection surgery. Methods From September 2019 to December 2022, 88 cases of patients with pterygium who underwent diagnosis and treatment at Qishan County Hospital of Traditional Chinese Medicine were selected as the research subjects. Accorded to a 1:1 random number table method, the 88 patients were divided into the corneal contact lens group of 44 cases and the control group of 44 cases. Both groups were treated with pterygium excision surgery, the control group were received routine postoperative treatment, and the contact lens group were treated with wearing contact lenses to observe and record the changes in visual quality of the patients. Results At 4 weeks after surgery, the optimal naked eye vision of the two groups were significantly higher than that of the first day before surgery (P<0.05), and the optimal naked eye vision of the contact lens group at 4 weeks after surgery were also significantly higher than that of the control group (P<0.05). The incidence rates of complications such as corneal edema, subconjunctival bleeding, delayed bleeding, and high intraocular pressure at 4 weeks after surgery in the contact lens group were 4.55%, compared to 20.45% in the control group. Compared to the incidence rates of complications in the control group, that in the ontact lens group were significantly lower (P<0.05). At 4 weeks after surgery, the corneal astigmatism values of the two groups were lower than those on the 1st day before surgery (P<0.05), and compared to the corneal astigmatism values of the control group, those of the contact lens group were also significantly lower (P<0.05). At 4 weeks after surgery, the eye symptom scores of the two groups were significantly lower than those on the 1st day before surgery (P<0.05), and compared to the eye symptom scores of the control group, those of the contact lens group were also significantly lower (P<0.05). Conclusion The application of corneal contact lenses after pterygium resection surgery can improve the best naked eye vision of patients, reduce the incidence of complications,decrease the corneal astigmatism value of patients, and continuously improve their eye symptoms.