Effect Analysis of Wandai Decoction Combined with Focused Ultrasound in the Treatment of Cervical Intraepithelial Neoplasia of Spleen Dampness

Abstract

Abstract: Objective To investigate and observe the therapeuticeffect of Wandai decoction combined with focused trasound in patients with cervical intraepithelial neoplasia and influence for body immune. Methods A total of 60 patients diagnosed with cervical intraepithelial neoplasia by cervical biopsy in Linyi Central Hospital from June 2021 to May 2022 were selected and randomly divided into control group (30 cases) and trial group (30 cases). The control group was treated with Haifu high-intensity focused ultrasound alone, and the trial group was treated with Wandai decoction combined with Haifu high-intensity focused ultrasound. After treatment, the curative effect, the negative conversion rates of human papillomavirus(HPV),TCM syndrome score, CD4⁺T, CD8⁺T, CD4⁺T/CD8⁺T were analyzed.the main symptoms scoreof TCM syndrome , the secondary symptoms scoreof TCM syndrome , and the blood immunological indexes (CD4⁺T, CD4⁺T, CD4⁺T/CD8⁺T) were analyzed. Results The curative effect in the experimental group was higher than that in the control group (P>0.05). After treatment, the D-value of Reid’s Colposcopy index in the trial group was higher than that in the control group (P<0.05), and the negative conversion rate of HPV in the trial group was higher than that in the control group at 3 months (P>0.05), After treatment, the scores of TCM syndromes in both groups were lower than those before treatment (P<0.05). and the scores of secondary symptoms in the experimental group were lower than those in the control group (P>0.05). After treatment, the lymphocyte ratio of CD4⁺T and CD4⁺T/CD8⁺T in both groups were significantly improved, and the experimental group was superior to the control group (P<0.05). Conclusion Wandai decoction combined with high intensity focused ultrasound has a better therapeutic effect on CIN patients, which can improve the TCM syndromes and balance the immune status of the patients, it is worthy of clinical application.

Key words: Wandai decoction, haifu high-intensity focused ultrasound, cervical intraepithelial neoplasia

CLC Number:

R287

YANG Sheng-nan, CAI Ying-xing, LI Yu-juan, LU Xiu-hua, DU Rui-chao, YAN Hua. Effect Analysis of Wandai Decoction Combined with Focused Ultrasound in the Treatment of Cervical Intraepithelial Neoplasia of Spleen Dampness[J]. ZHONGHUA YANGSHENG BAOJIAN, 2024, 42(15): 5-8.

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