Table of Content

01 November 2022, Volume 40 Issue 21

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Effect Evaluation of Clinical Pathway Optimization for Acute Myocardial Infarction Based on Single Disease Quality Control

LI Ling, YANG You-dong, LI Jian-tao, WANG Ya-li, GAO Xue-juan, ZHAO Xia, QU Fei, MENG Ze-jun, LI Juan

2022, 40(21):  1-3. 

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Objective To explore the optimal plan and effect of clinical pathway management for patients with acute myocardial infarction (AMI). Methods AMI patients discharged from the Third People's Hospital of Datong from January 2021 to March 2022 were collected. AMI cases were randomly selected in stages among patients included in the clinical pathway management according to the different times before and after optimization. The study group selected 204 patients included in the clinical pathway management one year before the implementation of the optimization (January 2021 to June 2021) were selected in the control group. The control group selected 225 patients included in the clinical pathway after implementing the optimization (November 2021 to March 2022). The mean hospitalization days, mean total hospitalization cost and the cost structure, and disease regression of patients in the two groups were compared and evaluated. Results The total hospitalization cost was lower than that of the control group, which was statistically significant (P<0.05). The treatment cost, operation cost and drug cost were lower in the study group than in the control group, and the difference was significant (P<0.05).The improvement rate of the transferred study group was higher than that of the control group, which was significant (P<0.05). Conclusion The optimization of the clinical path based on the quality management of single disease can standardize the diagnosis and treatment behavior, promote rational examination and rational drug use, and reduce medical costs.

Basic Skills and Model Application of Clinical Pharmacy Service Communication

LU Pan-pan, LI Hai-xin, ZENG Rui-feng, DENG Zhi-ling, LIANG Xu-jian, LU Yi-ting, XU Zhi-jie

2022, 40(21):  4-8. 

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Objective To explore the basic communication skills and the application of Medication-related consultation framework in clinical pharmacy services. Method By browsing existing books and literature retrieval to understand the basic skills of pharmacist-patient communication and the existing communication models that can be applied to clinical pharmacy services. Results Most studies on pharmacist-patient communication only involve the description of communication skills and value, and only a few scholars used models to explain effective communication for clinical pharmacy services. The article expounds on how to establish good relationship with patients, and listen carefully to the patients and express empathy, meanwhile in the communication using basic skills of clinical pharmacy services such as the verbal language, body language and written language. It also Introduced the application of Medication-related consultation framework in clinical pharmacy services. Conclusion Medication-related consultation framework can provide references for the improvement of communication skills of clinical pharmacists to help ensure medication safety and patient adherence, and improve the quality of clinical pharmacy services in hospitals.

Effects of Comprehensive Cognitive Impairment Training Combined with Omega-3 Fish Oil Fat Milk on Post-stroke Cognitive Impairment and Plasma Polyunsaturated Fatty Acid Levels

LI Xin, MO Fei

2022, 40(21):  9-12. 

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Objective To observe the combined supplement of comprehensive cognitive impairment training ω- 3. The clinical efficacy of fish oil fat emulsion in the treatment of post stroke cognitive impairment (PSCI) and its effect on the level of plasma polyunsaturated fatty acids. Methods 60 patients with PSCI who were hospitalized in the rehabilitation department of Jiangsu provincial government hospital from January 2019 to March 2022 were randomly divided into treatment group and control group according to the random number table method. There were 30 patients in both groups. The control group was given comprehensive cognitive impairment training, basic rehabilitation and drug treatment with donepezil tablets. The treatment group was increased on the basis of the control group ω- 3 fish oil fat emulsion injection was injected intravenously with 100 mL/d, once a day, seven times a week, for 3 weeks. Comparison of Mini-mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), modified Barthel index (MBI), omega-3 polyunsaturated fatty acids before and after treatment (omega-3polyunsaturated fatty acid, omega-3PUFA) levels. Results After treatment, MMSE score and MoCA score in the treatment group were higher than those in the control group,the difference was statistically significant (P<0.05); After treatment, the MBI score of the treatment group was higher than that of the control group,the difference was statistically significant (P<0.05); Patients in the treatment group after treatment the level of ω-3 PUFA was significantly higher than that of the control group, the difference was statistically significant (P<0.05). Conclusion comprehensive cognitive impairment training combined with Supplement ω-3 fish oil fat emulsion can improve cognitive function and ADL of PSCI patients faster, which is worthy of further clinical recommendation.

Efficacy of Dahuang Mudan Decoction in the Treatment of Advanced Metastatic Colorectal Cancer

WANG Qing-ying

2022, 40(21):  13-16. 

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Objective To investigate the curative effect of Dahuang Mudan Decoction in the treatment of advanced metastatic colorectal cancer and its influence on the level of serum tumor markers. Methods A total of 60 patients with advanced metastatic colorectal cancer who were admitted to Yangzhou Hospital of Traditional Chinese Medicine from January 2018 to December 2020 were selected as the subjects. All the cases were divided into the experimental group and the control group with 30 cases each groups accorded to the 1:1 random envelope drawing principle, the control group group were given conventional chemotherapy, and the experimental group were given Dahuang Mudan Decoction on the basis of the conventional chemotherapy group's treatment. The curative effects of the two groups were observed, the toxic and side effects of the patients were observed during the treatment, the serum carcinoembryonic antigen (CEA) and carbohydrate antigen (CA) 242 contents were detected before and after treatment, and the patients were evaluated for Karnofsky score before and after treatment (karnofsky performance status, KPS), followed up for 1 year after treatment, and recorded the survival of patients. Results After treatment, the total effective rate of the experimental group were higher than the control group (P<0.05). During treatment, the incidence of nausea and vomiting, anemia,leukopenia, and neutropenia in the texperiental group were lower than those in the control group (P<0.05). The KPS scores of the experimental group and the control group after treatment were higher than those before treatment, and the experimental group was higher than the control group (P<0.05). Serum CEA and CA242 levels after treatment in the two groups were lower than before treatment (P<0.05), and the experimental group were lower than the control group (P<0.05). All patients were followed up for 1 year, and the median survival time and median progression-free survival of the experimental group were longer than those of the control group (P<0.05). Conclusion Dahuang Mudan Decoction in the treatment of advanced metastatic colorectal cancer can improve the therapeutic effect, reduce the occurrence of toxic and side effects, inhibit the release of serum CEA and CA242, improve the quality of life of patients, and prolong the survival time of patients.

The Application Effect of Yigong Granule combined with Oxytocin in Patients with Uterine Involution After Cesarean Section

XIN Xing

2022, 40(21):  17-19. 

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Objective To analyze the application of Yigong granule combined with oxytocin in the treatment of patients with uterine involution after cesarean section and its effect on lactation. Methods The clinical data of 100 patients with uterine involution after cesarean section who were admitted to the First People's Hospital of Pingyuan County from January 2018 to December 2020 were selected for retrospective analysis, and divided into observation group (using Yigong Granule combined with oxytocin treatment, a total of 50 cases) and the control group (with oxytocin treatment, a total of 50 cases). The clinical efficacy, incidence of adverse reactions, daily milk production, average lochia volume, and disappearance time of low back and abdominal pain were compared between the two groups after one week of treatment. Finally, the changes in hormone levels before and after treatment were compared between the two groups. Results The clinical efficacy of the observation group was significantly higher than that of the control group (P<0.05); the daily lactation amount of the observation group was significantly higher than that of the control group after 1 week of medication (P<0.05), and the average amount of lochia, waist and abdominal pain disappeared time and other indicators were lower than those in the control group (P<0.05); there was no statistical significant difference in the adverse drug reaction incidence rate between the two groups (P>0.05); the differences in follicle-stimulating hormone, luteinizing hormone, estradiol, and progesterone between the two groups before treatment No significance (P>0.05), follicle-stimulating hormone, luteinizing hormone and estradiol in the observation group were higher than those in the control group (P<0.05), and progesterone was lower than that in the control group (P<0.05). Conclusion Yigong granule combined with oxytocin has a high curative effect, which helps to accelerate the involution of the uterus, relieve the symptoms of lochia and low back and abdominal pain, and at the same time helps to increase the milk production of the puerpera without increasing the adverse drug reactions. It is worthy of popularization and application.

Observation on the Curative Effect of Posterior Spinal Muscle Gap Approach Screw Rod System Fixation in the Treatment of Lumbar Fracture

ZHANG Xiao-jun

2022, 40(21):  20-23. 

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Objective To investigate the actual effect of lumbar spine fractures treated with screw-rod system fixation through the posterior intermuscular space approach. Methods A retrospective study of 80 patients with lumbar fractures who received surgical treatment in the Fourth People's Hospital of Tianshui City, Gansu Province from May 2017 to May 2022 were selected, and then standardized grouping was performed, according to different surgical plans, they were divided into control group and observation group, with 40 cases in each group. Control group used anterior pedicle screw fixation treatment, observation group used spinal muscle space approach screw rod system fixation treatment. The effects of the two surgical options on surgical indicators, imaging indicators and functional scores were compared. Results Before treatment, there was no significant difference in the imaging indicators, pain degree and low back function score between the two groups (P>0.05). After the treatment measures, the intraoperative blood loss in the observation group was lower, the difference was statistically significant (P<0.05); the differences in operation time and hospitalization time between the two groups were small (P>0.05). After the treatment measures, the loss of vertebral body anterior height index, the posterior vertebral body height loss index and the Cobb angle index of the two groups of patients were all decreased, and the cross-sectional area of the spinal canal were all increased (P<0.05); however, there was no significant difference in the imaging indicators between the two groups after treatment (P>0.05). After treatment, the pain degree and low back function scores of the two groups were reduced, while the observation group were lower than control group, and the difference was statistically significant (P<0.05). Conclusion In the treatment of patients with lumbar spine fractures, the use of posterior spinal intermuscular approach screw-rod system fixation has a significant effect, can effectively relieve the pain of patients, and promote the recovery of patients.

Effects of Moxibustion Combined with Pediatric Massage on Enlarged Mesenteric Lymph Nodes in Children with Acute Mesenteric Lymphadenitis

FANG Ru-yan

2022, 40(21):  29-32. 

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Objective To explore the effect of moxibustion combined with pediatric massage on enlarged mesenteric lymph nodes in children with acute mesenteric lymphadenitis. Methods A total of 96 children with acute mesenteric lymphadenitis who were treated in Yumen Traditional Chinese Medicine Hospital from March 2020 to March 2022 were prospectively selected as the research subjects. According to the random number table method, the children were divided into a traditional Chinese medicine group and a control group with 48 cases in each group. The control group were given routine required treatment, and the traditional Chinese medicine group were given moxibustion combined with pediatric massage on the basis of the treatment of the control group. Treatment and observation for 10 days, record the changes of enlarged mesenteric lymph nodes. Results After treatment, the total effective rates of the traditional Chinese medicine group were higher than that of the control group (P<0.05). The longitudinal and transverse diameters of mesenteric enlarged lymph nodes in the two groups after treatment were significantly smaller than those before treatment (P<0.05), and the TCM group was smaller than that in the control group (P<0.05). The disappearance time of fever, abdominal pain, vomiting, loss of appetite and other symptoms in the traditional Chinese medicine group was significantly shorter than that in the control group (P<0.05). The proportions of CD3⁺T lymphocytes and CD4⁺T lymphocytes in the two groups after treatment were significantly higher than those before treatment (P<0.05), and the TCM group was also significantly higher than that in the control group (P<0.05). The serum IgG and IgA contents in the two groups after treatment were significantly higher than those before treatment (P<0.05), and the TCM group was significantly higher than that in the control group (P<0.05). Conclusion Moxibustion combined with pediatric massage in the treatment of children with acute mesenteric lymphadenitis can improve the children's humoral immune function and cellular immune function, reduce the swelling of mesenteric swollen lymph nodes, and improve the overall clinical treatment effect.

Manipulative Bone Setting Combined with Regular Meridian Massage in the Treatment of Cervical Spondylosis

YE Min-fei, GE Dan-qin

2022, 40(21):  33-36. 

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Objective To explore the effect of manipulative bone setting combined with regular massage of meridians in the treatment of cervical spondylosis. Methods A total of 100 patients with cervical spondylosis of vertebral artery type who were admitted to Jianou Hospital of Integrated Traditional Chinese and Western Medicine from January 2020 to January 2022 were selected as the research objects, and they were divided into the observation group and the control group according to the random number table method, with 50 patients in each grop, patients in the control group received manual bone-setting therapy, and patients in the observation group received manual bone-setting combined with regular meridian massage therapy. The clinical efficacy, TCM syndrome scores, blood flow velocity, vertebral artery caliber, and quality of life were compared between the two groups. Results The total effective rate of treatment in the observation group was significantly higher than that in the control group (P<0.05); the scores of TCM syndromes such as limb numbness, limited activity, mental fatigue, dizziness and pain in the observation group were lower than those in the control group (P<0.05); comparison of blood flow velocity and vertebral artery caliber between the two groups before treatment,the difference was not statistically significant (P>0.05), the blood flow velocity and vertebral artery caliber were both increased in both groups after treatment, and the observation group was better than The control group (P<0.05); the QLQC30 scores of the two groups before treatment were compared,the difference was not statistically significant (P>0.05), the QLQC30 scores of the two groups were improved after treatment, and the observation group was higher than the control group (P<0.05). Conclusion Manipulative bone setting combined with regular meridian massage in the treatment of cervical spondylosis can significantly improve clinical efficacy, relieve clinical symptoms, increase blood flow, expand vertebral artery caliber, and improve the quality of life of patients, which is worthy of clinical promotion.

Effect of Wanfu Qutong decoction combined with rabeprazole on serum G-17, CA724 and PG levels in patients with chronic atrophic gastritis

GENG Liu-zhe

2022, 40(21):  37-39. 

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Objective To study the effect of Wanfu Qutong decoction combined with rabeprazole on the levels of serum gastrin-17 (G-17), carbohydrate antigen 724 (CA724) and pepsinogen (PG) in patients with chronic atrophic gastritis. Methods 70 cases of patients with chronic atrophic gastritis who were treated in Huangling County People's Hospital from January 2019 to December 2021were selected, and divided into two groups(the control group and observation group) according to the random number table method, with 35 cases in each group. The control group was treated with rabeprazole, and the observation group was treated with Wanfu Qutong Decoction on the basis of rabeprazole. The clinical efficacy in the two groups was compared. The levels of serum G-17, CA724 and PG in the two groups were detected, and the scores of TCM symptoms such as epigastric pain, tendency of warmness and pressing, fullness, generalized vomiting of clear water, four limbs burnout and anorexia were evaluated. Results The effective rate of the observation group was significantly higher than control group (P<0.05). Before treatment, there was no significant difference in the levels of serum G-17, CA724 and PG between the two groups (P>0.05). After treatment, the levels of serum CA724, PGⅠ and G-17 increased significantly (P<0.05), and the level of PGⅡ decreased significantly (P<0.05). The levels of serum CA724, PGⅠ and G-17 in the observation group were significantly higher than those in the control group (P<0.05), and the level of PGⅡ was significantly lower than that in the control group (P<0.05). Before treatment, there was no significant difference between the two groups in the scores of epigastric pain, tendency of warmness and pressing, fullness, generalized vomiting of clear water, four limbs burnout and anorexia (P>0.05). After treatment, the scores of the TCM symptoms above in the two groups decreased (P<0.05), and the observation group were significantly lower than those in the control group (P<0.05). Conclusion Wanfu Qutong decoction combined with rabeprazole has a significant effect on patients with chronic atrophic gastritis. It can effectively regulate the levels of serum G-17, CA724 and PG and reduce the degree of gastric mucosal injury.

Expression and clinical significance of CK19 and galectin-3 in thyroid papillary carcinoma complicated with Hashimoto's thyroiditis

GAO Dan, WU Ying, FU Xue-lian, LI Shu-lian, LI Hua-min, DONG Xiang-mei, FU Yao

2022, 40(21):  40-43. 

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Objective To investigate the expression and clinical significance of CK19 and galectin-3 in thyroid papillary carcinoma complicated with Hashimoto's thyroiditis (PCT-HT). Methods 100 patients with pct-ht treated in Hongqi Hospital Affiliated to Mudanjiang Medical College from August 2017 to August 2021 were selected as the research object and divided into the observation group. Another 100 patients with simple thyroid papillary carcinoma treated in our hospital in the same period were selected as the control group. The clinical characteristics and the expression levels of CK19 and Galectin-3 were compared between the two groups, and the correlation between CK19 and Galectin-3 and PCT-HT was analyzed, the clinical significance of CK19 and Galectin-3 in PCT-HT was analyzed by receiver operating characteristic curve (ROC curve). Results There was no significant difference in gender, age, tumor diameter and lymph node metastasis between the two groups (P>0.05). There were significant differences in tumor invasiveness, clinical stage and the expression of CK19 and Galectin-3 between the two groups (P<0.05). The proportion of patients with no tumor invasiveness in the observation group was significantly lower than that in the control group, the proportion of patients with clinical stage I-II was significantly lower than that in the control group, and the proportion of patients with positive CK19 and Galectin-3 was significantly higher than that in the control group; Spearman correlation analysis showed that CK19 and Galectin-3 were positively correlated with pct-ht (r=0.423, 0.539, P<0.05); The area under the diagnostic PCT-HT value curve of CK19 was 89.63, the best diagnostic coloring limit value was 75.73%, the area under the curve of Galectin-3 was 78.89, and the best color limit value was 82.53%. Logistic regression analysis showed that CK19 and Galectin-3 had independent predictive value for PCT-HT (P<0.05). Conclusion Patients with PCT-HT have higher tumor invasiveness and clinical stage, higher number of positive expression of CK19 and Galectin-3, and CK19 immunohistochemical staining area >75.73% and Galectin-3 >82.53% are related risk factors of PCT-HT. Therefore, in clinical practice, pathological examination of thyroid papillary carcinoma can be taken in time for patients with Hashimoto's thyroiditis with positive expression of CK19 and Galectin-3, so as to diagnose thyroid cancer early, and take targeted treatment measures.

Efficacy and Mechanism of Dengzhan Shengmai Capsule combined with Lovastatin in Elderly Patients with Coronary Heart Disease

WANG Guang-dong

2022, 40(21):  47-50. 

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Objective To investigate the efficacy and mechanism of Dengzhan Shengmai capsule combined with lovastatin in elderly patients with coronary heart disease. Methods 80 elderly patients with coronary heart disease admitted to Tianshui First People's Hospital from March 2020 to December 2021 were selected and divided into two groups according to the random number table method. The control group was treated with lovastatin, and the observation group was treated with Dengzhan Shengmai Capsules and lovastatin. The effective rate of treatment in the two groups was observed, the cardiac function indexes, homocysteine (Hcy), high-sensitivity C-reactive protein (hs-CRP) and uric acid (UA) levels in the two groups were detected, and the hemorheological indexes of the two groups were detected. Results The effective rate of the observation group was significantly higher than control group (P<0.05). Before treatment, there was no statistical significant difference in LVESV, LVEDD, LVEF and LVESD between the two groups (P>0.05). After treatment, LVESV, LVEDD, LVEF and LVESD in the two groups were significantly improved (P<0.05). The index was significantly better than the control group (P<0.05). Before treatment, there was no statistical significant difference in the levels of UA, hs-CRP and Hcy between the two groups (P>0.05). After treatment, the levels of UA, hs-CRP and Hcy in the two groups were significantly decreased (P<0.05). The levels of UA, hs-CRP and Hcy were significantly lower than those in the control group (P<0.05). Before treatment, there was no statistical significant difference in the erythrocyte aggregation index, plasma viscosity, maximum platelet aggregation rate and fibrinogen between the two groups (P>0.05). After treatment, the erythrocyte aggregation index, plasma viscosity, maximum platelet aggregation rate and fibrinogen between the two groups The erythrocyte aggregation index, plasma viscosity, maximum platelet aggregation rate and fibrinogen in the observation group were significantly lower than those in the control group (P<0.05). Conclusion Dengzhan Shengmai capsule combined with lovastatin has better curative effect on elderly patients with coronary heart disease, and the mechanism may be related to reducing the levels of UA, hs-CRP and Hcy, and regulating the levels of inflammatory factors.

Analysis of Curative Effect and Influencing Factors of Root Canal Retreatment after Removal of Bad Restorations

Rebiyamu· Haerder, XU Xu-dong, YANG Xiao-yan

2022, 40(21):  51-53. 

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Objective To investigate the efficacy and influencing factors of root canal therapy after removal of bad prosthesis. Methods A total of 80 patients with bad prostheses admitted to the Red Star Hospital of the 13th Division of Xinjiang Production and Construction Corps from May 2019 to May 2022 were selected. According to the different treatment methods, the patients were divided into study group and control group by random number table, with 40 patients in each group. The patients in the control group were given routine treatment, and the patients in the study group were treated with root canal therapy. The treatment effects, incidence of adverse reactions, VAS scores, tooth activity scores and periodortal index before and after treatment were compared between the two groups. Results The treatment effective rate of the study group was higher than that of the control group (P<0.05). There was no significant difference in VAS and tooth activity scores between the two groups before treatment (P>0.05). The VAS and tooth mobility scores in both groups were decreased, and the change in the study group was greater than that in the control group (P<0.05). The main adverse reactions in the two groups included pain, redness, hemorrhage, infection, pustules, occlusal disturbance, and soreness in the study group. The incidence of adverse reactions in the study group was lower than that in the control group, and the difference was not statistically significant (P>0.05). After treatment, the periodontal pocket probing depth (PPD), clinical attachment level loss (CAL), bleeding on probing (BOP), and sulcus bleeding index (SBI) in the study group were lower than those in the control group (P<0.05). Conclusion The effect of root canal therapy after removing the bad prosthesis can significantly reduce the occurrence of adverse reactions, reduce pain and improve the mobility of tooth, which has a certain reference value in clinical practice.

Effects of Stent Thrombectomy on the Levels of Vascular Endothelial Growth Factor and D-dimer in Patients with Acute Ischemic Stroke

FENG Yu, ZHOU Yan-long, XIN Ning

2022, 40(21):  57-60. 

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Objective To investigate the effects of stent thrombectomy on the levels of vascular endothelial growth factor and D-dimer in patients with acute ischemic stroke. Methods From January 2019 to February 2022, 84 cases of patients with anterior circalation infarction diagnosed and treated in Affiliated Hospital of Xuzhou Medical University were selected as the research subjects. According to the treatment method, the patients were divided into a thrombolysis group and a stent thrombectomy group, with 42 cases in each group. The stent thrombectomy group was given interventional therapy with stent thrombectomy, and the thrombolysis group was given intravenous thrombolysis. The changes in the expression levels of vascular endothelial growth factor and D-dimer in the two groups were detected. Results After treatment, the total effective rates of stent thrombectomy group were significantly higher than thrombolysis group (P<0.05). The peak systolic velocity (PSV) and end-diastolic velocity (EDV) of the middle cerebral artery in the two groups at treatment were significantly higher than those before treatment (P<0.05), and the stent thrombectomy group were significantly higher than the thrombolysis group (P<0.05). The levels of serum vascular endothelial growth factor and D-dimer in the two groups after treatment were significantly lower than those before treatment (P<0.05). The stent thrombectomy group were also significantly lower than the thrombolysis group (P<0.05). The incidence rates of cerebral transitional perfusion, venous thrombosis, infection and other complications in the stent thrombectomy group during the observation period were significantly lower than that in the thrombolysis group (P<0.05). Conclusion The application of stent thrombectomy in patients with cerebral infarction can inhibit the expression of serum vascular endothelial growth factor and D-dimer, it can also improve the blood flow velocity of the middle cerebral artery, thereby improving the overall treatment effect and reducing the incidence of complications.

Research Progress of Drugs for Acute Migraine Targeting CGRP and 5-HT_1F Receptors

CHEN Ya-ru, ZAI Feng-lei

2022, 40(21):  64-67. 

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Present,the acute treatment of migraine includes non-specific pain relief and triptan drugs.The limitations of these drugs include: lack of efficacy in many patients, many side effects, contraindications of triptan drugs in patients with cardiovascular disease, and so on, which indicate that the demand for new treatments for migraine has not been met. The pharmacological study of 5-hydroxytryptamine (5-HT) has promoted the development of triptan drugs (5-HT_1B/1D receptor agonists), some of which act on 5-HT_1F receptors. The exploration of the role of calcitonin gene-related peptide (CGRP) has led to the development of CGRP receptor antagonists. This article reviews the main progress in the acute treatment of migraine with CGRP and 5-HT_1F receptors in recent years.

A Meta-analysis of the Efficacy of Integrated Traditional Chinese and Western Medicine in the Treatment of Cerebral Infarction

HE Ming-long

2022, 40(21):  68-72. 

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Objective To systematically evaluate the clinical effect of integrated traditional Chinese and western medicine in the treatment of cerebral infarction by meta-analysis. Methods Using “cerebral infarction”, “ischemic stroke”, “integration of traditional Chinese and Western medicine”, “randomized controlled trials (RCTs)” as key words, data were collected in the Chinese Science and Technology Periodical Database (VIP) and Wanfang Database (WFD), China National Knowledge Infrastructure (CNKI), and China Biomedical Literature Database (CBM). The retrieval period ranged from January 2017 to January 2022, and relevant and valid original data in the literature were obtained, and the quality of the literature was evaluated by RveMan5.3 software. At the same time, RveMan5.3 was used for data analysis, which was evaluated by sensitivity analysis. The stability of the literature results, and the use of funnel plots to assess the possible publication bias of the literature. Results A total of 1447 Chinese literatures were retrieved in this study. According to the inclusion and exclusion criteria, a total of 9 literatures were included in this Meta-analysis. The heterogeneity test indicated that there was moderate heterogeneity among the studies, and a random effect model was used to determine the effect size. There was no heterogeneity between studies after Xiong Haitao 2017 was removed by sensitivity analysis, and the fixed effect model was used to merge the total effect value, and the combined RR (95%CI) was 1.22 (1.14, 1.30). The clinical effect of cerebral infarction was better than that of simple western medicine treatment (Z=5.91, P<0.001). In addition, the funnel plot showed that the left and right sides were basically symmetrical, suggesting that the publication bias may be small. Conclusion In clinical treatment, the clinical effect of the integrated traditional Chinese and western medicine treatment plan is better than the simple western medicine treatment plan.

Study on the Application Effect of Qi and Collateral Manipulative Nursing on Non-Specific Low Back Pain

FAN Chao, YANG Qiang

2022, 40(21):  82-85. 

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Objective Study on the application effect of qi and collaterals manipulative nursing on non-specific low back pain. Methods A total of 126 patients with non-specific low back pain who were diagnosed and treated in the Department of Traditional Chinese Medicine Rehabilitation of the Fourth Hospital of Baotou City, Inner Mongolia from January 2019 to January 2022 were retrospectively selected as the research subjects. According to the nursing methods, they were divided into a Qi and collateral manipulative group and a traditional group with 63 cases each. The traditional group were given routine functional exercise nursing, and the Qi and collateral manipulative group were given the Qi and collateral manipulative nursing on the basis of the treatment of the traditional group. Both groups were given nursing observation for 2 months. The overall curative effect of the two groups was observed, and the overall pain of myofascial trigger points, the activity of the waist joints, and the surface electromyography were evaluated before and after nursing. Results Before nursing, the visual analogue scale (VAS) of myofascial trigger point pain, the oswestry disability index (ODI) score of lumbar joint activity, the surface electromyography(sEMG) of flexion and dorsi-extension states, the difference was not statistically significant(P>0.05). After nursing, the VAS of myofascial trigger points, lumbar joint activity ODI scores and flexion state sEMG value of the two groups of patients were significantly lower than those before nursing, and the Qi and collaterals manipulation group was also significantly lower than the traditional group, the difference was statistically significant(P<0.05). The total effective rate of the Qi and collateral manipulative group after nursing which were significantly higher than the traditional group, the difference was statistically significant(P<0.05). Conclusion The application of Qi and collateral manipulative nursing in non-specific low back pain can relieve the pain of myofascial trigger points, improve lumbar function and surface EMG level, thereby improving the overall curative effects.