Abstract: Objective To explore the optimal plan and effect of clinical pathway management for patients with acute myocardial infarction (AMI). Methods AMI patients discharged from the Third People's Hospital of Datong from January 2021 to March 2022 were collected. AMI cases were randomly selected in stages among patients included in the clinical pathway management according to the different times before and after optimization. The study group selected 204 patients included in the clinical pathway management one year before the implementation of the optimization (January 2021 to June 2021) were selected in the control group. The control group selected 225 patients included in the clinical pathway after implementing the optimization (November 2021 to March 2022). The mean hospitalization days, mean total hospitalization cost and the cost structure, and disease regression of patients in the two groups were compared and evaluated. Results The total hospitalization cost was lower than that of the control group, which was statistically significant (P<0.05). The treatment cost, operation cost and drug cost were lower in the study group than in the control group, and the difference was significant (P<0.05).The improvement rate of the transferred study group was higher than that of the control group, which was significant (P<0.05). Conclusion The optimization of the clinical path based on the quality management of single disease can standardize the diagnosis and treatment behavior, promote rational examination and rational drug use, and reduce medical costs.

Key words: hospital administration, acute myocardial infarction, clinical pathway, quality control