Table of Content

01 November 2024, Volume 42 Issue 21

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The Effect of Cryotherapy and Drug Injection under Electronic Bronchoscopy in the Treatment of Pulmonary Tuberculosis Complicated with Bronchial Tuberculosis

HUANG Zi-qiang, ZHANG She, WU Jun-jie, ZHU Jing

2024, 42(21):  1-4. 

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Objective To evaluate the effect of electronic bronchoscopic freezing and drug injection in patients with pulmonary tuberculosis (PTB) complicated by bronchial tuberculosis (BT). Methods A total of 80 patients with PTB complicated with BT from May 2021 to August 2023 were included and grouped according to random number table method, namely: The control group (40 cases included and given conventional anti-tuberculosis treatment) and the observation group (40 cases included and given freezing and drug injection under electronic bronchoscopy) were evaluated for clinical response rate, immune function, inflammatory factors and time related to recovery. Results Compared with the control group, the clinical effective rate of the observation group was higher and the time related to rehabilitation was shorter, the difference was statistically significant (P<0.05). Before treatment, there were no significant differences in immune function (CD8⁺, CD4⁺, CD3⁺) and inflammatory factors [procalcitonin (PCT), C-reactive protein (CRP), interleukin-6 (IL-6)] between groups (P>0.05). After 4 weeks of treatment, CD8⁺, PCT, CRP and IL-6 were lower in the observation group, and CD4⁺ and CD3⁺ were higher, with statistical significance (P<0.05). Conclusion Freezing and drug injection under electronic bronchoscope for patients with PTB complicated with BT can improve clinical efficiency, enhance immune function, relieve inflammation, shorten the course of disease, and have clinical reference significance.

Assessment of College Students' Physical and Mental Health and Decision Support for Health Decisions through the Big Health Data Platform

CUI Li-na

2024, 42(21):  4-5. 

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Objective This study focuses on the application of big data platform in optimizing the health decision support system for school students, and analyzes in depth its multi-dimensional impact on students' physical and mental health, aiming to provide scientific basis for improving the health level of college students, and accordingly proposing precise and effective improvement strategies and intervention measures. Methods The study adopted a diversified data collection method, combining health checkups, AI robot technology, UPI personality questionnaire and SCL-90 psychological scale to comprehensively assess students' physical and mental health. All collected data were centrally managed, stored and intelligently analyzed through a big data platform to ensure the accuracy of the data and the comprehensiveness of the analysis. Results The study found that the BMI index was unevenly distributed among the student population; in terms of mental health, the proportion of psychological problems was higher among female students. Obsessive-compulsive symptoms, interpersonal sensitivity and paranoia were common psychological disturbances, especially the high prevalence of obsessive-compulsive symptoms, which highlights the urgency of psychological intervention. Conclusion The study reveals the dual challenges and gender differences in physical and mental health of freshmen in vocational colleges. It is recommended that schools make use of the big data platform to establish a comprehensive monitoring system, implement personalized health plans, and take into account both physical and mental health to promote students' all-round development.

A Survey and Study on the Psychological and Sleep Status of Medical Staff in Nanning

JIANG Chun-lei, LU Chang-mou, YAN Li-fu, ZHOU Ji-li

2024, 42(21):  8-12. 

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Objective To investigate the mental health status and sleep characteristics of medical staff in Nanning City, in order to develop intervention measures to help them recover a good psychological state. Methods A questionnaire survey was conducted on 175 medical staff using a general information questionnaire, the Symptom Checklist-90 (SCL-90), and the Athens Insomnia Scale (AIS) to analyze their psychological symptoms and sleep status characteristics. Results The scores of SCL-90 somatization, interpersonal sensitivity, hostility, and paranoia among medical staff were higher than the national norm, and the difference was statistically significant (P<0.05); AIS results showed that 45.14% of 175 people had no sleep disorders, 21.72% had suspected insomnia, and 33.14% had insomnia; The differential analysis of SCL90, AIS factor scores, and general demographic data among medical staff suggests that female medical staff have higher scores in interpersonal sensitivity factors than males, and unmarried and non solitary individuals have higher rates of insomnia than married and solitary individuals, and the difference was statistically significant (P<0.05). Conclusion There are positive symptoms in the mental health and sleep conditions of medical staff in Nanning City, and differentiated psychological interventions should be carried out according to the gender, marriage, and living conditions of medical staff.

A Study of The Effect of Betahistine Combined with Epley Maneuver on Vertigo Disorders and Vestibular Symptoms in Patients with Benign Paroxysmal Positional Vertigo

WANG Huan, YANG Xiao-jing

2024, 42(21):  12-16. 

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Objective This study aimed to investigate the effect of combining betahistine with Epley maneuver on vertigo disability and vestibular symptoms in patients with otolithiasis. Methods The information of 90 patients with otolithiasis was collated, all of which were indirectly diagnosed by the Eighth Medical Center of the PLA General Hospital from January 2021 to May 2024. All patients presented with vertigo disability and vestibular symptoms and were confirmed through nystagmus test and complex vestibular reflex test. The patients were randomly divided into a control group (treated with betahistine) and an observation group (treated with betahistine combined with Epley maneuver) based on the principle of random number table. The vertigo disability and balance ability scores before and after treatment, vestibular symptom scores after treatment, and clinical efficacy were collected and compared between the two groups. Results Before treatment, the vertigo disorder and balance ability scores of the two groups were comparable at baseline, and after treatment,the dizziness handicap scores in both groups decreased, and the balance ability scores increased simultaneously, but after treatment, the dizziness handicap scores in the observation group were lower than those in the control group, and the balance ability scores were higher than those in the control group(P<0.05). After treatment, the scores of six vestibular symptoms of dizziness, nausea, headache, vertigo, balance and visual sensitivity in the observation group were observably lower than the scores of six vestibular symptoms in the control group (P<0.05). The clinical efficacy rate in the observation group (95.56%) was higher than that in the control group(P<0.05). Conclusion For vertigo disorder and vestibular symptoms in patients with otolithiasis, betahistine combined with Epley maneuver reduction can improve vertigo disorder, alleviate vestibular symptoms, improve balance ability, and achieve better efficacy.

Clinical Study on the Treatment of Phlegm Stasis Blocking Collateral Type Cerebral Infarction in the Recovery Period with Huazhuo Xingxue Decoction

NING Hong

2024, 42(21):  19-23. 

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Objective To explore and analysis the clinical effect of Huazhuo Xingxue Tang on the recovery stage of cerebral infarction of phlegm stasis obstruction type. Methods A total of 98 patients with phlegm stasis obstruction type cerebral infarction during the recovery period diagnosed and treated at Hedong District Traditional Chinese Medicine Hospital in Tianjin from August 2020 to February 2023 were selected as the research subjects. Accorded to a 1:1 random number table method, the 98 patients were divided into the traditional Chinese medicine group of 49 cases and the control group of 49 cases. The control group were treated with conventional Western medicine, while the traditional Chinese medicine group were treated with Huazhuo Xingxue Tang on the basis of the control group. Both groups were treated and observed for 2 months, and the scores of nerve function deficit, mental state and cognitive function, changes in middle cerebral artery blood flow velocity and quality of life were compared between the two groups before and after treatment. Results After 2 months of treatment, the neurological deficit scores of both groups of patients decreased compared to before treatment, and the degree of downregulation in the traditional Chinese medicine group was greater. Compared with the control group, the difference was statistically significant (P<0.05); After 2 months of treatment, the mental state and cognitive function scores of the two groups of patients increased compared to before treatment, and the degree of increase was greater in the traditional Chinese medicine group. Compared with the control group, the difference was statistically significant (P<0.05); The end diastolic blood flow velocity and peak systolic blood flow velocity of the middle cerebral artery in the two groups of patients treated increased compared to before treatment, and the degree of increase in the traditional Chinese medicine group was greater. Compared with the control group, the difference was statistically significant (P<0.05); The quality of life scores of the traditional Chinese medicine group after two months of treatment showed a significant increase compared to the control group, and the difference was statistically significant (P<0.05). Conclusion Huazhuo Xingxue Tang can improve patients' neurological deficits, improve their mental state and cognitive function scores, improve the blood flow velocity of the middle cerebral artery, and thus improve their quality of life in the recovery period of phlegm stasis obstruction type cerebral infarction.

Effects of Tongbi Qushi Huoxue Decoction on Symptom Scores and Serum Factors of Patients with Blood-Vacuity Wind-Dryness Psoriasis

LIU Wei

2024, 42(21):  23-27. 

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Objective To investigate the effects of Tongbi Qushi Huoxue Decoction and Zidan-Yinzhuo capsule on symptom scores and serum factors of patients with blood-deficiency wind-dryness psoriasis. Methods Ninety-four patients with blood deficiency and wind psoriasis admitted to our hospital from January 2021 to June 2023 were divided into two groups with 47 patients in each group. Both groups received conventional western medicine treatment, the control group was treated with purple Dan psoriasis capsule, the observation group was treated on the basis of the control group, both groups were treated for 12 weeks. Compare symptom integration, disease improvement, serum factors, and clinical efficacy between the groups. Results After 12 weeks of treatment, the total score of the main and secondary symptoms in the observation group was lower than that in the control group (P<0.05). After 12 weeks of treatment, the water content of the stratum corneum in the observation group was higher than that in the control group, while the PASI score and the number of joint pain/swelling were lower than those in the control group (P<0.05). After 12 weeks of treatment, the levels of IL-6, CRP, and OPN in the observation group were lower than those in the control group (P<0.05). After 12 weeks of treatment, the total effective rate of the observation group was higher than that of the control group (P<0.05). Conclusion On the basis of conventional western medicine, Tongbi Qushi Huoxui Decoction is used to treat blood deficiency wind-dryness psoriasis, which can promote the recovery of skin lesions, joint pain and other symptoms, reduce inflammatory substances, and improve clinical effect.

Evaluation Value of Biochemical Indexes of Renal Function in Prognosis of Patients with Acute Pulmonary Embolism

WANG Xiao-yu

2024, 42(21):  43-47. 

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Objective To investigate the prognostic value of biochemical indexes of renal function in patients with acute pulmonary embolism. Methods The data of 231 patients with acute pulmonary embolism treated in the People's Hospital of Inner Mongolia Autonomous Region from January 2020 to December 2023 were retrospectively analyzed. The outcomes of the patients were divided into good outcomes and poor outcomes. Describe the outcomes of all patients (grouping). Univariate analysis of prognosis in patients with acute pulmonary embolism and multivariate analysis of prognosis in patients with acute pulmonary embolism. Predictive model and efficacy of prognosis in patients with acute pulmonary embolism. Results Of the 231 patients included in the study, 85 (36.80%) were judged to have a poor prognosis and 146 (63.20%) were judged to have a good prognosis. The results of univariate analysis showed that there were statistically significant differences in creatinine clearance, urea nitrogen, uric acid, cystatin C, sodium ion and calcium ion levels among patients with different prognosis (P<0.05). logistic multivariate analysis obtained the model equation as follows: ln (P/1-P) =23.853-0.106×creatinine clearance +0.372×urea nitrogen+0.008×uric acid +2.926×cystatin C-9.909×Ca²⁺. The nomogram risk model was constructed based on the variables screened by multi-factor analysis, and the C-index was 0.792. The average absolute error of calibration curve is 0.022. The ROC curve was used to predict the prognosis of patients with acute pulmonary embolism using independent influencing factors and P-value prediction probability, and the areas under the curve were 0.930, 0.698, 0.714, 0.656, 0.733, 0.966, respectively. Conclusion Creatinine clearance, urea nitrogen, uric acid, cystatin C and calcium levels are closely related to poor short-term prognosis in patients with acute pulmonary embolism. Monitoring renal function biochemical indexes in the diagnosis and treatment of patients with acute pulmonary embolism may help reduce adverse prognostic events.

The Therapeutic Effect of Different Proton Pump Inhibitors on Hp Infected Gastric Ulcers and Their Impact on Interleukin-33 and miR-26a Levels

GUO Lan-xin, LIU Yi-fang

2024, 42(21):  53-56. 

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Objective To explore the therapeutic effect of different proton pump inhibitors on Helicobacter pylori (Hp) infected gastric ulcers and their impact on interleukin-33 and miR-26a levels. Methods A study was conducted on 86 patients with Hp infected gastric ulcers admitted to the People's Hospital of Lintong District, Xi'an City from June 2022 to June 2023. Divide into two groups using the random number table method, with 43 cases in each group. The control group was given a proton pump inhibitor (omeprazole enteric coated tablets)+colloidal pectin bismuth capsules+clarithromycin tablets+metronidazole tablets quadruple treatment plan, while the observation group was given a proton pump inhibitor (esomeprazole magnesium)+colloidal pectin bismuth capsules+clarithromycin tablets+metronidazole tablets quadruple treatment plan. Compare the total effective rate, Hp eradication rate, the levels of interleukin-33, miR-26a, CD4⁺, CD8⁺, CD4⁺/CD8⁺ between two groups. Results The total therapeutic effect of the observation group was higher than that of the control group, with statistical significance (P<0.05); The Hp eradication rate in the observation group was higher than that of the control group, with statistical significance (P<0.05). After treatment, the levels of IL-33 in both groups were significantly reduced, while the levels of miR-26a were significantly increased. The level of IL-33 s in the observation group was lower than that in the control group, while the level of miR-26a was higher than that in the control group (P<0.05). After treatment, the levels of CD4⁺ and CD8⁺ in both groups showed significant improvement, with the former showing an increase and the latter showing a decrease. The level of CD4⁺ and the ratio of CD4⁺/CD8⁺ in the observation group were higher than those in the control group, while the level of CD8⁺ was lower than those in the control group (P<0.05). Conclusion Compared to omeprazole enteric coated tablets, esomeprazole magnesium can improve clinical treatment efficacy and Hp eradication rate in patients, reduce the level of interleukin-33, increase the level of miR-26a, and improve immune function.

Exploration of the Application of SCL Integrated Teaching Method in the Teaching of Nephrology to Undergraduate Students-an Example of Chronic Renal Failure

WANG Bao-dong, HE Juan, ZHANG Yuan-lin, YAN Pan, CHENG yao, LI Mei

2024, 42(21):  78-81. 

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Objective To analyse the application effect of SCL (Seminar-case learning) integrated teaching method in theory teaching in nephrology teaching. Methods Two classes of students were randomly selected from the clinical five-year undergraduate class A of the class of 2022 and the control class B of the class of 2021 of Shanxi Medical University as the observation group and the control group as the research subjects. SCL teaching method was used for 36 students in the observation group; 32 students in the control group were taught by traditional teaching. The teaching effect of SCL integrated teaching method was assessed by comparing the scores of follow-up exams, comprehensive application ability, independent learning ability and teaching satisfaction after teaching in the two groups. Results Comparative analysis showed that observation group students' mean post-test scores were higher than control group students' mean post-test scores, and this difference is statistically significant (P<0.05). The scores of students' comprehensive ability and independent learning ability in the observation group were higher than those in the control group, and the difference was statistically significant (P<0.05). All of the students' teaching satisfaction scores in the observation group, including teaching style, classroom motivation, classroom atmosphere, learning efficiency, and classroom goal achievement, were higher than those in the control group, and the difference was statistically significant (P<0.05). Conclusion SCL integrated teaching method used in the theory teaching of nephrology can promote the combination of students' independent learning and interactive learning, stimulate students' interest and attention to learning, improve students' theoretical performance and comprehensive literacy.

The effect of Integrated Traditional Chinese and Western Medicine Nursing on Preventing Venous Thromboembolism after Elderly Femoral Head Replacement Surgery

YANG Li, LI Jiong

2024, 42(21):  92-95. 

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Objective To study the preventive effect of integrated traditional Chinese and Western medicine nursing on postoperative venous thromboembolism (VTE) in elderly patients undergoing femoral head replacement surgery. Methods From May 2021 to November 2023, 88 elderly patients who underwent femoral head replacement surgery at the Taizhou Integrated Traditional Chinese and Western Medicine Hospital were selected as the study subjects. The patients were divided into groups using odd and even numbers. The control group (n=44) received only routine care, while the study group (n=44) received a combined traditional Chinese medicine nursing plan on the basis of the control group, targeting postoperative coagulation function indicators in both groups Compare and observe the occurrence of limb swelling, quality of life, and nursing satisfaction. Results After nursing, compared with the control group, the levels of plasma fibrinogen (FIB), fibrinolytic products (FDP), and D-dimer (D-D) in the study group were all lower than those in the control group, with statistical significance (P<0.05); The incidence of limb swelling in the study group was lower than the control group, and the difference was statistically significant (P<0.05); Comparing the scores of physiological, psychological, and physical functions between the two groups, the study group had higher scores than the control group, and the difference was statistically significant (P<0.05); Comparing the satisfaction levels of the two groups, the study group showed higher scores in VTE assessment, VTE prevention, service attitude, and professional skills compared to the control group, with statistically significant differences (P<0.05). Conclusion For elderly patients undergoing femoral head replacement surgery, integrated traditional Chinese and Western medicine nursing can effectively promote the recovery of coagulation function, reduce the risk of VTE, and improve their postoperative quality of life, which has received high satisfaction from patients and has good clinical application value.

Effect of Symptom Rehabilitation Strategy in Breast Cancer Patients

WANG Li-zhen, SONG Jun-feng, DONG Zhe, XUE Wei-zhen

2024, 42(21):  95-99. 

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Objective To explore the impact of symptom rehabilitation strategies on the recovery of postoperative breast cancer patients. Methods From June to August 2023, 140 postoperative breast cancer patients at Meizhou People's Hospital in Guangdong Province were randomly assigned to an observation group or a control group, with 70 patients each. The control group received routine care, while the observation group received additional symptom rehabilitation strategies. The Disabilities of the Arm, Shoulder, and Hand (DASH) score, Constant-Murley Shoulder Score Questionnaire, and a complication registration form were used to assess and compare upper limb mobility, shoulder joint dysfunction, and complication incidence before and after care in both groups. Results The observation group had significantly lower DASH scores and higher shoulder function scores for pain, range of motion, muscle strength, daily living ability, and local morphology compared to the control group (P<0.05). The incidence of complications such as lymphedema, subcutaneous effusion, axillary web syndrome, and poor wound healing was significantly lower in the observation group (P<0.05). Conclusion Symptom rehabilitation strategies effectively improve upper limb mobility and shoulder joint function while reducing complication rates in breast cancer surgery patients, making them valuable for clinical practice.

The Impact of an Internet-based Multidisciplinary Team Nursing Model on the Self-management Ability and Quality of Life of Hemophilia Patients

ZHAO Shan-shan

2024, 42(21):  147-150. 

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Objective To analyze the impact of an internet-based multidisciplinary team nursing model on the self-management ability and quality of life of hemophilia patients. Methods From June 2021 to June 2023, 80 hemophilia patients in Heze Traditional Chinese Medicine Hospital were selected as the research subjects. They were randomly divided into two groups using a random number table method. The control group (n=40) received routine nursing care, while the observation group (n=40) received multidisciplinary team nursing based on the Internet. Compared the self-management ability (ESCA), quality of life (QOL), and incidence of complications between two groups. Results There was no statistically significant difference (P>0.05) in MOCA score, ESCA scale scores, and QOL scores between the two groups before nursing. However, compared with the control group after nursing, the observation group showed significantly higher MOCA score, ESCA scale scores, and QOL scores after nursing, and the difference was statistically significant (P<0.05). The incidence of complications in the observation group was significantly lower than that in the control group, and the difference was statistically significant (P<0.05). Conclusion Relying on the Internet to provide multidisciplinary team nursing for hemophilia patients can not only alleviate their negative emotions, but also enhance their self-management ability, effectively reduce the risk of complications, and improve their quality of life.

Director Li Hui's Experience in Diagnosis and Treatment of Chronic Atrophic Gastritis

YANG Shu-hao, XU Xiang-xiang, LI Hui

2024, 42(21):  166-168. 

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Chronic atrophic gastritis (CAG) is a common gastric precancerous disease closely related to gastric cancer. Modern medicine lacks effective treatment methods, and traditional Chinese medicine has outstanding advantages. Director Li Hui, based on years of experience, believes that the pathogenesis of this disease is based on qi deficiency and dampness and stasis. The basic treatment should focus on strengthening the spleen and stomach, dispelling dampness and unblocking collaterals. Clinical use of modified Shidan granules and a combination of traditional Chinese and Western medicine has yielded satisfactory results. This article summarizes Director Li Hui's experience in combining traditional Chinese and Western medicine to treat CAG, for reference by colleagues.

The Impact of Abnormal Glucose Metabolism on Ischemic Stroke and Its Prevention and Treatment Strategies

LIU Zhi-juan

2024, 42(21):  169-172. 

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Abnormal glucose metabolism can lead to oxidative stress, chronic inflammation and endothelial dysfunction through multiple pathways, which may impair vascular remodeling and growth, and eventually lead to cerebrovascular disease and its triggers. Based on the study of the correlation between abnormal glucose metabolism and stroke, this paper discusses the influence of abnormal glucose metabolism on ischemic stroke, in order to guide the prevention and treatment of ischemic stroke caused by abnormal glucose metabolism.

Professor Tang Yixin's Experience in Treating Henoch Schonlein Purpura Nephritis with Deficiency of Qi and Yin from Spleen

LIU Bin, XU Xiao-mei, CHENG Liang-ying

2024, 42(21):  172-175. 

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Western medicine clinically mainly uses immune regulation, urinary protein reduction, anti-inflammatory, anti-platelet and blood purification as the main treatment methods, but Western medicine alone has a poor therapeutic effect, and long-term use of drugs has relatively large side effects. In traditional Chinese medicine, wind-heat toxins are the cause of pathogenic factors. The body has heat, viscera deficiency, damp-heat content, spleen and kidney deficiency, blood stasis blocking the collaterals; mainly heat, deficiency, blood stasis, wind, dampness, and poison. For pathogenesis, traditional Chinese medicine focuses on promoting blood circulation to remove blood stasis, dispersing wind and heat, cooling blood and removing toxins, and replenishing kidney and cooling blood. Professor Tang Yixin treats from the spleen and treats patients with allergic purpura nephritis with hematuria and edema as the main manifestations of Qi and Yin deficiency. The treatment is based on the method of sweetening the spleen, nourishing yin and distilling water, and adding and reducing the spleen soup. The treatment has also achieved good clinical results.

A Case of Advanced Gastric Cancer Treated with Sintilimab injection

JIN Yong-jie, LI Yan, YU Xiao-wei, FANG Mei-hua, XU Zheng-guo, HU zheng-jun, SHEN Huan, TONG Xin

2024, 42(21):  175-180. 

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Advanced gastric cancer patients urgently need to improve their clinical efficacy due to factors such as poor tolerance to chemotherapy drugs, targeted drugs, and fewer advantageous populations. In recent years, immunotherapy has emerged rapidly, and the latest research shows that the combination of Sintilimab injection and chemotherapy provides a new first-line standard treatment for advanced gastric cancer patients. A case of advanced gastric cancer is reported. Through advanced treatment with traditional Chinese medicine combined with Sintilimab injection, the tumor was significantly reduced, metastatic lesions were eliminated, tumor staging was reduced, and surgical conditions were created; After surgery, secondary abdominal wall metastasis occurred, and traditional Chinese medicine combined with Sintilimab injection combined with chemotherapy and radiotherapy was used to complete eradication treatment, ultimately achieving successful transformation and cure. At present, the patient's condition has been evaluated by CR and continuous follow-up. The diagnosis of OS has lasted for a total of 52 months until the last evaluation, and the patient is still healthy and has survived for over 60 months. The clinical effect is significant, and this report is for reference by colleagues.

The Value of Five Tests for Penta-test for Vaginitis Combined with Microscopic Microscopy in the Diagnosis of Vaginitis in Infertile Women

HE Wei

2024, 42(21):  181-184. 

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Objective To investigate the value of the penta-test(penta-test) for vaginitis combined with microscopic microscopy(microscopy) in the diagnosis of vaginitis in infertile women. Methods A total of 226 infertile female patients with suspected vaginitis attending Jiuquan People's Hospital from January 2020 to December 2023 were selected for the study, and all of them underwent microscopic microscopic examination of vaginal secretions (for bacterial, trichomonas, candida, and leukocyte counts) with the vaginitis penta-test (a penta-test kit was used to test the specimens for six indices: pH value, level of leukocyte esterase, hydrogen peroxide, and proline aminopeptidase, sialidase, and acetylaminoglucosidase), and compare the positive detection rates of microscopy, penta-test and the combined test for vaginitis. To compare the diagnostic efficacy of the three different tests for vaginitis and the detection rates of different pathogens of vaginitis. Results 226 seventy-two cases of vaginitis were diagnosed in infertile female patients with suspected vaginitis, with a detection rate of 31.86%. 49 cases were detected positively by the microscopic method, 60 cases were detected positively by the penta-test method, and 68 cases were detected positively by the combined test, and the sensitivity, specificity and accuracy of the combined test were significantly higher than that of the microscopic method and the penta-test method (P<0.05). The difference in the detection rate of bacteria and trichomonas was not statistically significant when comparing the detection rates of the combined test and the pentameric method (P>0.05). Conclusion Vaginitis 5 combined with microscopic examination can increase the positive detection rate of vaginitis and the detection rate of different pathogens of vaginitis, and the diagnostic efficacy is higher.