Table of Content

01 February 2024, Volume 42 Issue 3

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The Clinical Feature and Treatment Prognosis of Amiodarone-Induced Pulmonary Toxicity

ZHANG Sen-sen, ZHANG Na-xin

2024, 42(3):  1-4. 

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Objective Amiodarone is the most commonly used antiarrhythmic drug, and interstitial pneumonia is its serious adverse reaction. This study aims to explore the clinical feature and treatment prognosis of amiodarone-induced diffuse interstitial pneumonia. Methods A case of amiodarone-induced diffuse interstitial pneumonia was retrospectively analyzed in terms of clinical manifestations, imaging feature, treatment and outcome. Results The elderly male patient appeared to have symptoms of cough, dyspnea after use of amiodarone for 1.5 months. The course of disease develops rapidly, followed by type Ⅰ respiratory failure. After symptomatic treatment, withdrawal of amiodarone, non-invasive ventilator assisted breathing, administration of hormones, the clinical symptoms disappeared. Conclusion The diagnosis of amiodarone-induced diffuse interstitial pneumonia should be based on medication history, combined with clinical and imaging findings. The key to successful treatment is to discontinue amiodarone, give corticosteroid and ventilator therapy in severe patients.

Clinical Observation of Fengxuan Decoction Combined with Western Medicine in the Treatment of Hyperactivity of Liver Yang in Patients with Essential Hypertension

WANG Rui, NIE Qian, XIE Wen

2024, 42(3):  4-7. 

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Objective Exploring the clinical efficacy evaluation of self-made Fengxuan Formula cooperate with Western medicine in the treatment of primary hypertension with liver yang hyperactivity type. Methods From October 2020 to September 2022, 100 patients with primary hypertension who met the criteria Chengdu University of TCM Cardiovascular Department 2 Outpatient were assigned into research group and control group on the basis of the table of random number, 50 cases were fit into each group. The control group was given Western medicine, and another was grant Fengxuan Decoction combined with conventional Western medicine. After 12 weeks, Compare total effective rate,Side effects and 24-hour mean blood pressure level of the two groups. Results Before treatment,there was no statistically significant difference in 24-hour average systolic and diastolic blood pressure between the study group and the control group (P>0.05). After treatment, the total effective rate of the study group was significantly higher than that of the control group, and the result was statistically significant (P<0.05). The 24-hour ambulatory blood pressure systolic and diastolic blood pressure of the study group were lower than those of the control group.Relatively statistically significant (P<0.05). There was no significant difference in adverse reactions incidence rate between the two groups (P>0.05). Conclusion on the foundatin of Western medicine, adding self-made Fengxuan Decoction in the treatment of primary hypertension with hyperactivity of liver yang can notable improve the effective rate and amplitude of blood pressure reduction, which can be applied to clinical practice.

Clinical Observation of Liver Nourishing Serum Heart Decoction in the Treatment of Liver Blood Deficiency Type Insomnia

XU Meng-yuan, SUN Ping, YANG Yan-fu

2024, 42(3):  8-11. 

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Objective To observe the clinical effect of Bugan Yangxue Qingxin decoction on insomnia. Methods A total of 60 patients with insomnia with hepatic blood deficiency admitted to Lu'an Hospital of Traditional Chinese Medicine from December 2021 to December 2022 were selected as the research objects, and they were divided into observation group and control group, with 30 cases in each group. The control group used dexzopiclon, the observation group added a decoction of Yangxue Qingxin bugan based on the control group, 1 dose/dan, take two doses one day. Treatment cycle 8 weeks, compare the difference before and after the results of the TCM syndrome score, PSQI and PSG, assessment of the effect of clinical treatment. Results Analysis of reference indexes after 8 weeks of systemic treatment: the overall effectiveness of the observation groups was 93.33%, this exceeded the total effectiveness ratio of 76.67% in the control group;Also to find,TCM syndrome score, PSQI score and PSG index of both groups were statistically analyzed and concluded that,the difference is statistically significant (P<0.05). That is, the symptoms improve.Comparison between groups, the improvement of observation group was the greater one, the difference is statistically significant (P<0.05). Conclusion Bugan Yangxue Qingxin decoction could ease sleep disorders. It is more effective when used in combination with Western medicine.

Application and Effect Evaluation of Discharge Guidance Scheme Based on IMB Model in Patients Undergoing Radical Resection of Lung Cancer

WU Ruo-jia, YANG Jiao, ZHAO Yan-qiu, YANG Jing, DONG Kai-wen, SHEN Nan, YANG Xiu-mei

2024, 42(3):  11-15. 

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Objective To investigate the application effect of discharge guidance scheme based on IMB model on perioperative patients with lung cancer. Methods A total of 106 patients who were admitted to the Department of Thoracic Surgery of Yunnan Cancer Hospital from April to October 2021 were selected. According to the order of admission, they were divided into control group and intervention group, with 53 cases in each group. The control group was given routine discharge guidance, and the intervention group was given discharge guidance intervention based on IMB model. The general data, the length of hospital stay, discharge readiness and discharge guidance quality of the two groups were compared. Results The comparison of the average length of hospital stay and discharge readiness scores between the two groups of patients showed that the observation group was better than the control group, and the difference was statistically significant (P<0.05). The score of discharge guidance quality of the two groups was superior to that of the control group in all sub-dimensions and total score except the dimension of need information (P<0.05). Conclusion The discharge guidance scheme based on IMB model can shorten the hospital stay of patients, improve the quality of discharge preparation and guidance, and provide reference for improving the quality of clinical nursing and continuing nursing action.

The Significance and Correlation of Serum TNFAIP8, HE4, and FSH in Ovarian Cancer

HUANG Lei, ZHANG Gui-hua

2024, 42(3):  15-18. 

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Objection To explore the expression significance of serum tumor necrosis factor-α inducing protein 8 (TNFAIP8), human epididymal protein-4 (HE4), and follicle stimulating hormone (FSH) in ovarian cancer, and the correlation between the above indicators and their significance in the diagnosis of ovarian cancer. Methods 88 patients diagnosed with ovarian cancer in our hospital from August 2019 to October 2022 were selected as the study group, and 50 patients diagnosed with benign ovarian lesions in our hospital during the same period were selected as the case control group. The differences in serum TNFAIP 8, HE4, and FSH between the two groups were compared. According to the pathological examination results, the study group patients were classified into FIGO stages, and the differences in serum TNFAIP 8, HE4, and FSH levels among ovarian cancer patients at different stages were compared, Using Pearson correlation analysis to explore the correlation between serum TNFAIP8, HE4, and FSH in ovarian cancer patients, and calculating the diagnostic efficacy of serum TNFAIP8, HE4, and FSH in ovarian cancer by plotting ROC curves. Results The serum levels of TNFAIP8, HE4, and FSH in the study group were significantly higher than those in the control group (P<0.05). According to the pathological examination results, the study group patients were divided into Ⅰ+Ⅱ subgroup and Ⅲ+Ⅳ subgroup. The comparison showed that the serum levels of TNFAIP 8, HE4, and FSH in the Ⅲ+Ⅳ subgroup patients were significantly higher than those in the Ⅰ+Ⅱ subgroup patients (P<0.05). Pearson correlation analysis showed that serum TNFAIP8 levels in ovarian cancer patients were positively correlated with their HE4 and FSH levels (r=0.221, P<0.05;r=0.594, P<0.05), while HE4 levels were positively correlated with their FSH levels (r=0.163, P<0.05). Draw serum TNFAIP8, HE4, and FSH levels to differentiate ovarian cancer ROC curves, and calculate their AUC as 0.924 (95%CI=0.969~0.979, P<0.05), 0.909 (95% CI=0.850~0.967, P<0.05), and 0.757 (95%CI=0.659~0.856,P<0.05), respectively. Conclusion The serum TNFAIP8, HE4 and FSH levels will show abnormal elevated manifestations, and they may be related to the pathological stage of patients, so the above factors can be considered in the differential diagnosis of ovarian cancer.

Observation on the Effect of Acupoint Application of Tongbian Paste on Prospective Prevention of Constipation in Young and Middle-Aged Patients with Myocardial Infarction

HONG Li-jun, XIANG Hui-fang, MA Yue, WU Xie

2024, 42(3):  22-25. 

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Objective To observe the curative effect of point application of Tongbei ointment on prospective prevention of constipation in young and middle-aged myocardial infarction patients. Methods A total of 90 young and middle-aged patients with myocardial infarction under 60 years admitted to Suzhou Hospital of Traditional Chinese Medicine from January 2021 to December 2022 were enrolled were randomly divided into experimental group and control group, 45 cases in each group. The control group was treated with routine nursing, and the experimental group was treated with acupoint application of the self-made laxative paste. The two groups were evaluated by the constipation Patient Symptom Self-Rating Scale (PAC-SYM), constipation TCM Syndrome Score and Emotion Scale (SAS, SDS) during hospitalization. Results After intervention, the PAC-SYM score, constipation TCM syndrome score and the abnormal number of mood scale in the experimental group decreased significantly than the control group (P <0.05), and the incidence of constipation was significantly lower than that in the control group (P<0.05). Conclusion The prospective prevention of constipation in young and middle-aged patients with myocardial infarction can significantly improve the self-evaluation of defecation symptoms, TCM syndrome evaluation and negative emotion regulation, which is worth of application.

Effect Analysis of Shengdi Point Balancing Acupuncture Combined with Manipulation Massage and Bioelectric Stimulation of Postpartum Pelvic Floor Dysfunction

YU Li-ping

2024, 42(3):  25-28. 

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Objective To explore the effect of balance acupuncture combined with manipulation massage and bioelectric stimulation of postpartum pelvic floor dysfunction. Methods A total of 126 patients with postpartum pelvic floor dysfunction admitted to Rongcheng Maternal and Child Health Hospital of Shandong Province from August 2021 to January 2023 were selected as the study objects, and were divided into experimental group and control group according to computer random number table method, with 63 cases in each group. The two groups were treated with routine education, the control group was treated with bioelectric stimulation, and the experimental group was treated with balanced acupuncture and manipulative massage on the basis of the control group. The therapeutic effect, the change of pelvic floor muscle strength, the electromyography value of class I to II muscle fibers and the quantitative staging score of pelvic organ prolapsis (POP-Q) were compared between the two groups. Results There was no difference in Class Ⅰ, Class Ⅱ electromyography and muscle fiber fatigue between the two groups before treatment (P>0.05). After treatment, class Ⅰ and class Ⅱ electromyography values were higher than before treatment, while muscle fiber fatigue was lower in the two groups, while class Ⅰ and class Ⅱ electromyography values in the experimental group were higher than that in the control group, while muscle fiber fatigue was lower than that in the control group (P<0.05). After treatment, 0 degree was higher in both groups than before treatment, Ⅰ degree was lower than before treatment, and the number of 0 degree cases in experimental group was more than that in control group, but the number of Ⅰ degree cases was less than that in control group (P<0.05). The total effective rate of experimental group was higher than that of control group (P<0.05). There was no difference in physical discomfort symptoms between the two groups after treatment (P>0.05). Conclusion Balanced acupuncture combined with manipulation massage and bioelectric stimulation in the treatment of PFD can improve the electro myoelectric value of pelvic floor and promote the recovery of muscle strength, with good effect and high safety.

Evaluation of Prognostic Value of Hemodynamic Parameters of Renal Parenchymal Arterioles in Elderly Patients with Hypertension

WANG Hui, JIANG Xue-zhong, LIU Xiao-jing, HE Ping, HE Rui

2024, 42(3):  38-41. 

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Objective To explore and analysis the prognostic values of hemodynamic parameters of renal parenchymal arterioles by color Doppler ultrasound in elderly patients with hypertension. Methods From August 2022 to March 2023, 88 cases of elderly patients with essential hypertension who were diagnosed and treated in a certain hospital were selected as the study subjects, all the cases to determine the occurrence of renal injury in the patients. The color Doppler ultrasound were used to examine the hemodynamic parameters of renal parenchymal arterioles in all patients, and correlation analysis were performed. Results In the 88 patients, there were 18 cases (20.45%) had renal injury. There were no significant differences in gender, age, systolic blood pressure, diastolic blood pressure, body mass index, and heart rate compared between the renal injury group and the non renal injury group (P>0.05). The levels of urinary microalbumin, serum creatinine, and blood urea nitrogen in the renal injury group were significantly higher than those in the non renal injury group (P<0.05). The renal length, renal cortical thickness, and renal width in the renal injury group were significantly increased compared with those in the non renal injury group (P<0.05). The end diastolic blood flow velocity and the maximum systolic flow velocity of the renal parenchymal arterioles in the renal injury group were lower than those in the non renal injury group (P<0.05), and the pulsation index and resistance index were significantly higher than those in the non renal injury group (P<0.05). In the 88 patients, Spearman correlation analysis showed that the occurrence of renal injury were correlated with end-diastolic blood flow velocity, maximum systolic flow velocity, pulsation index, and resistance index of renal parenchymal arterioles (P<0.05). Conclusion The probability of renal injury in elderly patients with essential hypertension is relatively high, which can cause changes in the renal structure and hemodynamic parameters of renal parenchymal arterioles. The hemodynamic parameters of renal parenchymal arterioles can evaluate the prognosis of patients with renal injury.

Application of Serum HCY and Lp-PLA2 Levels in the Efficacy of Oxygenation and Blood Transfusion after Ischemic Stroke

FENG Lin

2024, 42(3):  42-45. 

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Objective To analyze the clinical effect of serum homocysteine (HCY) and lipoprotein-associated phospholipase A2 (Lp-PLA2) levels in the efficacy of oxygenation and blood transfusion after ischemic stroke. Methods A total of 80 patients with ischemic stroke admitted to Lingcheng District People's Hospital from December 2019 to December 2022 were selected as the study subjects, and served as the experimental group. At the same time, 80 healthy people were admitted at the same time were selected as the control group. The experimental group was divided into three subgroups according to National Institute of Health stroke scale (NIHSS), that is, mild subgroup (NIHSS<5 points), moderate subgroup (NIHSS 5~15 points) and severe subgroup (NIHSS≥15 points). The research was done retrospectively. The levels of serum HCY, Lp-PLA2 and LPA were compared between the two groups. At the same time, patients with ischemic stroke were treated with oxygenation and blood transfusion, and the levels of HCY, Lp-PLA2 and LPA before and after treatment were compared. Results The levels of HCY, Lp-PLA2 and LPA in the experimental group were significantly higher than those of the corresponding indices (P<0.05). The levels of HCY, Lp-PLA2 and LPA in severe nsubgroup were significantly higher than those of mild and moderate subgroups, and the levels of indicators above moderate subgroup were higher than those of mild subgroup (P<0.05). The levels of HCY, Lp-PLA2 and LPA in the experimental group after treatment were lower than those before treatment, and the difference was statistically significant before and after treatment (P<0.05). The plasma viscosity, whole blood high shear viscosity, whole blood low shear viscosity, hematocrit and platelet adhesion rate of the experimental group after treatment were decreased significantlycompared with those before treatment (P<0.05). Conclusion The levels of serum HCY and Lp-PLA2 are higher in patients with ischemic stroke, and monitoring the levels of serum HCY and Lp-PLA2 during oxygenation and blood transfusion in patients with ischemic stroke can be used as an effective indicator for disease monitoring and prognosis evaluation.

The Therapeutic Effect of Ultrasound-Guided Microwave Ablation on Hydatid disease of the Liver and Analysis of Risk Factors on Postoperative Infection

Genggarenqing

2024, 42(3):  45-49. 

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Objective To explore the therapeutic effect of ultrasound guided microwave ablation on liver hydatid disease and the risk factors of postoperative infection. Method The clinical data of 90 patients with hepatic echinococcosis admitted to Yushu People's Hospital from August 2020 to April 2022 were retrospectively analyzed. The patients were grouped according to different treatment methods. 32 patients treated with conventional open surgery were divided into control group, and 48 patients treated with ultrasound-guided microwave ablation were divided into observation group. All patients were followed up for 1 year to compare the incidence of complications. Subsequently, the patients with postoperative infection were divided into two subgroups, namely infected group (n=21) and non-infected group (n=59). The risk factors affecting postoperative infection of hepatic hydatidosis were analyzed, and logistic regression analysis was applied to analyze the independent influencing factors of postoperative infection of hepatic hydatidosis. Result The total response rate of the observation group was 89.58%, the total response rate of the control group was 87.50%. There was no statistical difference between the two groups (P>0.05). The incidence of postoperative complications such as infection, ascites, bile leakage, and liver insufficiency in the observation group was higher than that in the control group (P<0.05). There were no significant differences in gender, lesion site, combined hypertension, hyperlipidemia, other related underlying diseases, hydatid types, postoperative subphrenic effusion or residual cavity between the non-infected group and the infected group (P>0.05). There was no statistical significance in age, proportion of patients diagnosed with diabetes, surgical method, drainage indentation time and hepatic hydatid history between the non-infected group and the infected group (P<0.05). Age, proportion of patients diagnosed with diabetes, operation method, drainage indentation time and hepatic hydatid history were independent risk factors for postoperative infection of hepatic hydatid (OR=2.774, 95% CI=1.876~4.010, P=0.016; OR=0.371, 95% CI=1.876~4.010, P=0.021; OR=0.544, 95% CI=1.876~4.010, P=0.009; OR=0.747, 95% CI=1.876~4.010, P=0.024; OR=0.526, 95% CI=1.876~4.010, P=0.013). Conclusion Both ultrasound-guided microwave ablation and conventional open surgery have significant therapeutic effects on liver hydatid disease, but adopting ultrasound-guided microwave ablation can reduce the incidence of postoperative complications in patients. In addition, for older patients with diabetes and a history of liver echinococcosis, microwave ablation should be used as far as possible to reduce the drainage tube retention time to prevent postoperative infection.

Effect of Double Incision and Double Plate Internal Fixation on Fracture Union and Joint Stability of Schatzker V-type Tibial Plateau Fracture

YANG Jin-hu, YANG Da-lei

2024, 42(3):  49-53. 

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Objective To investigate the effect of double incision and double plate internal fixation on fracture union and joint stability of Schatzker V-type tibial plateau fracture. Methods Clinical data of 60 patients with Schatzker V-type tibial plateau fracture admitted to Rizhao People's Hospital from January 2020 to December 2022 were retrospectively analyzed. According to different surgical methods, 30 patients treated with double incision and double plate internal fixation were set as the observation group, and 30 patients treated with unilateral locking plate fixation were set as the control group. The operation related indexes, knee function, joint stability, daily living ability, balance ability, quality of life and complications were compared between the two groups. Results There was no significant difference in operation time, incision length and postoperative hospital stay between the two groups (P>0.05). The intraoperative blood loss and postoperative drainage volume in the observation group were higher than those in the control group, and the fracture healing time was shorter than that in the control group (P<0.05). The daily life, pain, joint deformities and total score of WOMAC in the observation group were lower than those in the control group 3 months after surgery, and the difference was statistically significant (P<0.05). The TPA and PA of the observation group were lower than those of the control group 3 months after operation (P<0.05); The BI scores and BBS scores of the observation group were higher than those of the control group 3 months after operation (P< 0.05). The WHOQOL-BREF scores in the observation group were higher than those in the control group at 3 months after operation(P<0.05). There was no significant difference in complications between the two groups (P>0.05). Conclusion Double incision and double plate internal fixation for the treatment of Schatzker V-type tibial plateau fracture is more effective, which can improve joint stability, shorten fracture healing time, enhance daily activity ability, and is safe and reliable.

The Teasibility of TEAS Combined with Core Machine Training for Postpartum Rectus Abdominis Muscle Separation and Low Back Pain

XUN Guan-biao, LI Jin-xia, XIE Jing-jun, GUO Xiao-qing, WANG Ya-ling, PAN Zhong-qiang, FU Rui-yang

2024, 42(3):  62-66. 

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Objective To analyze the correlation between rectus abdominis separation and low back pain after delivery and the feasibility of Transcutaneous Electrical Acupoint Stimulation (TEAS) combined with core training intervention. Methods Selecting 90 postpartum low back pain patients from Huzhou Traditional Chinese Medicine Hospital affiliated with Zhejiang University of Chinese Medicine as the research subjects, Pearson correlation analysis was conducted between the degree of rectus abdominis separation and the score of low back pain. They were randomly divided into 3 groups: control group, treatment group 1 and treatment group 2 (30 cases in each group). Control group: conventional postpartum natural recovery method. Treatment group 1: on the basis of the control group, core muscle training, once a day, 5 times a week, 4 weeks as a course of treatment, consecutive 1 course of treatment. Treatment group 2: On the basis of treatment group 1, TEAS was used, once a day, 5 times a week, 4 weeks as a course of treatment, one course of treatment. The degree of rectus abdominis muscle separation (IRD), low back pain symptoms (SF-MPQ) and Body Mass Index (BMI) were evaluated before and after treatment, and the changes of these indexes were observed before and after treatment. Results After treatment, the degree of rectus abdominis muscle separation (IRD), low back pain symptoms (SF-MPQ) and Body Mass Index (BMI) were significantly decreased in each group (P<0.05), and the decrease was most significant in the two groups (P<0.05). There was a positive correlation between the degree of rectus abdominis diastasis and low back pain score （r=0.320, P<0.05）. Conclusion Rectus abdominis diastasis is associated with low back pain. TEAS combined with core muscle training can effectively improve postpartum rectus abdominis muscle separation, reduce low back pain, and reduce the Body Mass Index. It indicated that the therapy could be feasible for clinical.

Clinical Efficacy and Cardiac Function Impact of Exercise Rehabilitation Therapy for Patients with Coronary Heart Disease and Chronic Heart Failure

LI Jian-fei, ZHU Wang-liang, WANG Zhi-yong, REN Xi-jun

2024, 42(3):  66-70. 

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Objective To compare the clinical effect and effect of motion rehabilitation treatment for patients with chronic heart failure in coronary heart disease. Methods 76 patients with chronic heart failure in Inner Mongolia Autonomous Region People's Hospital from November 2019 to March 2021 were diagnosed as research objects and randomly grouped. During the treatment, the control group (n=39) received conventional health guidance, and the test group (n=37) received sports rehabilitation treatment. The NYHA's heart functional grading, ultrasonic heart dynamics, exercise tolerance indicators, heart indexes, heart blood emissions, heart beats, and clinical prognosis differences of two groups were compared. Results After 6 months of treatment, the NYHA's heart functional grading of the test group was better than that of the control group (P<0.05), the indicators were better than the control group (P<0.05), the clinical prognosis of the test group was lower than the control group and the survival rate was higher than the control group (P<0.05), the volume and heart fighting volume was higher than the control group (P<0.05). Conclusion Sports rehabilitation treatment can actively improve the heart function and body movement tolerance of patients with chronic heart failure in coronary heart disease, reduce the risk of cardiovascular adverse events, increase the prognosis survival rate, and have significant effects.

A Probe Into the Treatment of Dementia by Abdominal Acupuncture Based on the Multi-Layer Regulation Theory of "Heaven, Earth and Man"

JIANG Shuai, ZHENG Min, WANG Zi-dong, ZHANG Yu-rong, LI Yong

2024, 42(3):  77-81. 

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As a chronic neurodegenerative disease, dementia is characterized by cognitive memory impairment. The pathogenesis of dementia is complicated, and there are no specific clinical drugs. The basic pathogenesis of dementia is the deficiency of marrow sea and the failure of magic machine. Deficiency of yin essence, qi and blood is based on deficiency; qi, fire, phlegm and blood stasis block brain collaterals inside, so the treatment of dementia needs to regulate viscera from the inside and dredge channels and collaterals from the outside. Abdominal acupuncture therapy has its unique efficacy in the treatment of dementia. It is based on meridians and viscera, with the overall concept and syndrome differentiation of viscera as the core. Abdominal acupoints are longitudinally divided into three layers: heaven, human and earth according to the depth of acupuncture, and each level. According to the location of pathological changes, meridians and related viscera projected on the abdomen, acupoints can play a role in regulating and controlling different systems according to syndrome differentiation. It can regulate the relevant parts of the lesions, meridians and viscera respectively, so as to achieve the purpose of treating both the symptoms and the root causes of dementia. Based on the close relationship between abdomen and brain, this paper organically combines the characteristics of abdominal acupuncture regulating different systems according to levels and parts with the pathogenesis of dementia, and probes into a new idea of clinical application of abdominal acupuncture in the treatment of dementia and other encephalopathy.

The Value of Combining Liquid-Based Cytological Detection of Pleural and Ascitic Fluid with Agar Paraffin Double Embedding Section Method in Pathological Detection

TIAN Li, WU Yang-chun

2024, 42(3):  81-84. 

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Objective To explore and analysis the values of liquid based cytology combined with agar paraffin double embedding section method for pathological detection of pleural and ascitic fluid sediment. Methods From March 2019 to September 2022, 92 cases of patients with pleural and ascitic fluid who were diagnosed and treated at a certain hospital were selected as the research subjects. All patients were underwent liquid based cytology testing of pleural and ascitic fluid combined with agar paraffin double embedding section method for pleural and ascitic fluid sediment. Pathological biopsy were also performed to determine the diagnostic value. Results There were 54 cases were diagnosed as malignant tumors and 38 cases were diagnosed as benign tumors by pleural and ascitic fluid based cytology in the 92 cases. The sensitivity and specificity of pleural and ascitic fluid based cytology in diagnosing malignant tumors were 85.48% and 96.67%, respectively. The sensitivity and specificity of agarose paraffin double embedding sections in the diagnosis of malignant tumors were 88.71% and 100.00%, respectively, and 56 cases of malignant tumors and 36 cases of benign tumors were detected by the method. The sensitivity and specificity of agarose paraffin double embedding section detection of pleural and ascitic fluid sediment in diagnosing malignant tumors were 98.39% and 100.00%, respectively, and 61 cases of malignant tumors and 31 cases of benign tumors were detected by the method. The positive rates of human epidermal growth factor receptor 2, synaptophysin, and chromaffin A expression in malignant tumor patients were 40.32%, 41.94%, and 43.55%, respectively, which were significantly higher than those in benign tumor patients （10.00%, 13.33%, 10.00%, P<0.05）. The sensitivity of the combination of liquid based cytology detection of pleural and ascitic fluid and agar paraffin double embedding section method for the diagnosis of benign and malignant tumors is higher than that of single detection （P<0.05）, and there is no significant difference in the diagnostic specificity of different detection methods （P>0.05）. The ROC curve analysis showed that the diagnostic curve for benign and malignant tumors using liquid based cytology combined with agar paraffin double embedding section method for pleural and ascitic fluid sediment were 0.883. Conclusion The application of liquid based cytology combined with agar paraffin double embedding section method in pathological detection of pleural and ascitic fluid can improve diagnostic sensitivity, it can also maintain very high diagnostic specificity, and have great value in determining the benign and malignant nature of primary tumors in patients.

Bibliometrics Analysis of Retinitis Pigmentosa Based on Citespace

XIONG Meng, YU Chang, REN Bao-ping, ZHONG Mei-qi, ZENG Mei-yan, YUAN Cheng-zhi, SUN Qi-fang, LU Jing, PENG Qing-hua, SONG Hou-pan

2024, 42(3):  85-89. 

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Objective Based on Bibliometrics, this paper explores the research status and hot frontiers of Retinitis pigmentosa (RP) at home and abroad in recent 20 years. Methods Retrieve literature related to RP experimental and clinical studies from the CNKI database and the Web of Science Core Collection (WoSCC) database, and use Citespace for visual analysis. Results A total of 2277 articles were selected, with 354 in CNKI and 1923 in WoSCC, respectively. The overall annual publication volume is on the rise. The First Affiliated Hospital of Hunan University of Chinese Medicine and the University of London are the institutions with the largest publication volume among CNKI and WoSCC, respectively. Peng Qinghua and Peng Jun are the authors who published the most literature in CNKI, and Tsang Stephen H is the author who published the most literature in WoSCC. Keyword analysis shows that the research focus of literature in WoSCC is genetics and Genomics, while the research focus of literature in CNKI is TCM treatment. Conclusion This study uses Citespace software to analyze the current status of RP research, clarify the current research hotspots and frontiers, and provide new ideas and theoretical references for researchers who are interested in this field.

Study on the Effect of Internet + Continuous Nursing Services with Spinal Health Management in Community Health Care for Puerperium Women

ZENG Rui-fen, ZHAN Tian-yu, YU He-gao, LI Xiao-ling, CAO Xiang-zhu, ZHANG Fu-ying

2024, 42(3):  99-102. 

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Objective To Explore the application effect of spinal health management guided by Internet continuous nursing services on the recovery of puerperal women during community postpartum visits. Methods 200 healthy primiparous women who delivered at full term and were assigned by the Shenzhen Maternal and Child Health Information Platform to 22 social health centers under our hospital from October 2021 to February 2023 were selected as the study subjects. The study subjects were randomly divided into an intervention group and a control group in a 1∶1 ratio. Among them, the control group conducted postpartum visits according to routine requirements, and the intervention group conducted postpartum visits to the puerpera based on the control group combined with the spinal health management service method under the guidance of Internet+ continuous nursing services. The two groups of puerpera were followed up by telephone on the 30th and 90th day after delivery, respectively, to evaluate the spinal comfort, pure breastfeeding rate and Edinburgh Postpartum Depression Scale scores of the two groups of puerpera. Results After the intervention, the spinal comfort and pure breastfeeding rate of the intervention group were significantly higher than the control group, and the Edinburgh Postpartum Depression Scale score was lower than the control group. The differences between the groups were statistically significant （P<0.05）. Conclusion Under the guidance of Internet + continuous nursing services, the application of spinal management in community postpartum visits can effectively improve the spinal comfort of puerperal women and the rate of pure breastfeeding, and improve the ability of postpartum self-care of puerperal women, which is worth promoting.

Exploration of Hierarchical Progressive Teaching Model in the Cultivation of Nutrition Specialist Nurses

DING Qing-qing, WU Zhuo-wei, XU Guang-li, WANG Ai-hua, DING Zi-yu, LI Jia-jia, SHAO Shang-wen, LIU Hui-fan

2024, 42(3):  106-109. 

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Currently, nutrition therapy has become an important part of disease treatment, and its effective implementation requires professional nursing. Cultivating qualified nutrition specialist nurses is a key factor in improving the quality of clinical nutrition therapy. However, there are still some problems in China's current nutrition specialist nurses training programs, such as significant differences in trainee' starting points, low enthusiasm for teaching activities, and insufficient clinical teaching resources. The hierarchical progressive training model is guided by differences and sets progressive and upward phased training objectives based on the trainees' different education levels, professional titles, work departments, and work experience. Its core purpose is to improve nutrition specialist nurses' clinical professional ability, leadership and management ability, professional and humanistic qualities, guidance and collaboration ability and professional development ability. This article focuses on the characteristics of nutrition specialist nurse training and explores a series of programs and measures for hierarchical progressive training, aiming to provide references for improving the training effectiveness of nutrition specialist nurses.

Research on the Application of the O2O Teaching and Assessment Mode based on the Feynman Learning Method in CPR Training for Young Nurses

YAO Kai-feng, ZHU Xiao-xiao

2024, 42(3):  113-117. 

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Objective To explore the application effect of the O2O teaching and assessment mode based on the Feynman learning method in the CPR training for young nurses. Methods 80 nurses from the Nantong First People's Hospital between March 2019 and March 2022 were randomly selected as the subjects of this study. The nurses were divided into two groups using the random number table method. The control group implemented the routine teaching of CPR, while the experimental group implemented the O2O teaching and assessment model based on the Feynman learning method. After the teaching, the theoretical scores and operational scores of nurses in the two groups were compared by examination, and the differences in clinical competence, professional identity and learning satisfaction of nurses in the two groups were compared by questionnaire. Results After implementing the O2O teaching model based on the Feynman learning method, the theoretical scores of the nurses in the experimental group were significantly higher than those of the nurses in the control group, and the operational scores of the nurses in the experimental group were significantly higher than those of the nurses in the control group, with statistically significant differences (P<0.05). After the implementation of this teaching model, the clinical competence of the nurses in the experimental group was significantly higher than that of the nurses in the control group in the areas of critical thinking, clinical care, leadership, interpersonal relationship, legal ethical practice, professional development and educational consultation, with a statistically significant difference (P<0.05). After the implementation of this teaching model, the nurses in the experimental group had a significantly higher sense of professional identity than the control group in terms of sense of consistency, sense of control, sense of patient influence, sense of self-determination, sense of self-efficacy, sense of meaningfulness and sense of organisational influence, with a statistically significant difference (P<0.05). After implementing this teaching model, the nurses in the experimental group were significantly more satisfied with their learning than the control group, with a statistically significant difference (P<0.05). Conclusion The application of the Feynman Learning Method-based O2O teaching model assessment model in cardiopulmonary resuscitation training for young nurses to improve nurses' ability to master relevant knowledge and skills, enhance learning interest and professional identity, and increase nurses' satisfaction with the training.

Effect of Two-Dimensional Code Video-Assisted Functional Exercise on Improving the Participation, Compliance and Joint Function of Patients with Distal Radius Fracture Splint External Fixation

YU Aorui, ZHANG Yun, LI Wei, QIN Guo-zhong, HUO Qing-yun, ZENG Fan-yu

2024, 42(3):  170-173. 

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Objective To investigate the effect of two-dimensional code video-assisted functional exercise in improving the application effect of splint external fixation in patients with distal radius fracture (DRF). Methods A total of 100 patients with DRF who received splint external fixation in the hospital from March 2019 to March 2022 were selected and divided into control group (n=50) and study group (n=50) by random number table method. The patients in the control group were given functional exercise therapy, and the patients in the research group were given two-dimensional code video-assisted therapy on the basis of the control group. The wrist performance, wrist mobility, participation, compliance and quality of life were compared between the two groups. Results The overall compliance rate of patients in the study group was higher than that in the control group (P<0.05). After 3 months of treatment, the Gartland-Werley wrist joint score, palmar inclination angle, ulnar declination angle, grip strength and 36-item short form survey (SF-36) scores in the two groups were all higher than those before treatment (P<0.05). The objective, subjective and total scores of Gartland-Werley wrist joint score, wrist palm inclination angle, ulnar declination angle, grip strength and SF-36 score in the study group were higher than those in the control group (P<0.05). Conclusion Two-dimensional code video-assisted functional exercise can effectively improve the participation and compliance of patients with DRF splint external fixation, improve wrist function, and improve the quality of life of patients.

Clinical Application of Hollow Base in Denture Repair of Severe Alveolar Ridge Atrophy

LIU Guo cun, LU Shi gang

2024, 42(3):  173-177. 

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Objective To solve the problem of reduction of retention stability caused by excessive weight of prosthesis due to too thick base in the repair of severe alveolar ridge atrophy denture, and to improve the repair effect. Methods From November 2018 to April 2022, 20 patients with severe alveolar ridge atrophy and dentition loss were selected as the study subjects according to the inclusion and exclusion criteria from the Shan County Central Hospital affiliated to Jining Medical College. The experiment was conducted as a self control study. Each patient was treated with a hollow base to make a prosthesis and a traditional method to make a prosthesis, respectively. Among them, the group using a hollow base to make a prosthesis was treated as the experimental group, The prosthetic group was made using traditional methods. The masticatory efficiency and satisfaction were tested on the 7th and 31st days after the patient wore the prosthesis, and the data were recorded and analyzed statistically. Results On the 7th day, the masticatory efficiency of the experimental group was higher than that of the control group (P<0.05), and the satisfaction with comfort, retention, and mastication was higher than that of the control group (P<0.05). There was no difference in the satisfaction with appearance, language, and firmness between the experimental group and the control group (P>0.05); On the 31st day, the masticatory efficiency was higher than that of the control group (P<0.05), and the satisfaction with mastication, retention, comfort, appearance, and language was higher than that of the control group (P<0.05). There was no difference in the satisfaction with firmness between the control group and the control group (P>0.05). Conclusion Hollow base can solve the problem of reduction of retention stability caused by excessive weight of denture due to too thick base in the repair of severe alveolar ridge atrophy denture, and improve the masticatory efficiency and satisfaction of patients.