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Table of Content

    16 May 2024, Volume 42 Issue 10
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    Clinical and Imaging Features of Chlamydia Psittaci Pneumonia in Elderly Patients: an Analysis of 28 Cases
    ZHANG Sen-sen, WANG Hong-lei, ZHANG Na-xin
    2024, 42(10):  1-5. 
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    Objective To study the clinical characteristics, laboratory tests, imaging findings, and treatment strategies for Chlamydia psittaci pneumonia in elderly patients. Methods A retrospective analysis was performed for the treatment of 28 case of Chlamydia psittaci pneumonia diagnosed via metagenomic next-generation sequencing technology (mNGS) from August 2020 to August 2023 in our hospital. The data of all patients on medical history, clinical manifestations, laboratory tests, chest computer tomography (CT) performance, treatment and prognosis of patients were collected. Results Among the 28 patients, there were 16 males and 12 females, with a mean age of (72.1±8.8) years. There were three patients who raised pigeon and four patients who raised parrot. The onset to admission interval was (5.6±3.0) days, and hospital stay was (14.3±4.3) days. The clinical manifestations included fever, cough, sputum, palpitations and diarrhea. The laboratory tests: white blood cell count was (6.8±2.2) ×109/L, the proportion of neutrophils was (81.1±8.7）×109/L, C-reactive protein level was 155（126.5）mg/L. Chest CT showed a variety of manifestations: consolidation, consolidation with ground-glass opacity, ground-glass opacity, bronchial inflatable sign, anti-halo sign, pleural effusion, etc. The CURB-65 score was (1.43±0.84), and the PSI score was (109.75±32.97). In terms of treatment, 16 patients were treated with moxifloxacin alone, 5 patients with levofloxacin alone, 4 patients with piperacillin tazobactam and minocycline, 2 patients with carbapenem plus minocycline, and 1 patients with carbapenem plus moxifloxacin. There were 5 patients received high-flow oxygen inhalation. All patients recovered. The relationship between hospitalization time and CURB -65 score, PSI score, gender, C-reactive protein, and chest CT findings: there was statistically significant correlation between PSI score and hospitalization time; C-reactive protein has statistical significance with hospitalization time; bilateral lobar involvement and hospitalization time were statistically significant; the rest were not statistically significant. Conclusion As the CRP and PSI score increase and bilateral lung lobes are affected, the patient’s hospitalization time prolongs, and quinolone antibiotics are effective against Chlamydia psittaci pneumonia. Elderly patients have multiple underlying diseases, and community-acquired pneumonia is prone to multiple organ dysfunction and progression to severe illness. Early identification of pathogens is necessary to shorten the course of the disease and improve prognosis.
    Exploring the Diagnostic Value of Intelligent Pelvic Floor Ultrasound Combined with Transluminal OmniView 3 D Ultrasound in Female Pelvic Floor Dysfunction Diseases
    NIU Hongxia, CHE Xinyu, SEINIYA Manafu
    2024, 42(10):  6-9. 
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    Objective To investigate the diagnostic value of intelligent pelvic floor ultrasound combined with transOmniView 3D ultrasound in female pelvic floor dysfunction diseases. Methods A total of 2000 female patients with pelvic floor dysfunction treated from January 2021 to July 2023 were selected as the case group, and 2000 healthy women with no pelvic floor dysfunction in the hospital were selected as the control group. All populations were given intelligent pelvic floor ultrasound combined with transluminal OmniView 3D ultrasound to record ultrasound features and determine the diagnostic value. Results There was no significant difference in the comparison of intelligent pelvic floor ultrasound-bladder neck position and the bladder posterior angle (P>0.05), and the degree of bladder neck movement in the case group was significantly higher than that in the control group (P<0.05). The relevant indicators of intraluminal Omni View-anterior and posterior diameter, periferential diameter of levator fissure, left and right diameter of levator fissure, and fissure area of levator fissure were significantly lower than that of the control group (P<0.05). Intelligent pelvic floor ultrasound combined with the cavity OmniView 3 d ultrasound for pelvic floor dysfunction disease detection rate is significantly higher than simple intelligent pelvic floor ultrasound (P<0.05). The ROC curve analysis showed that the area under the curve of intelligent pelvic floor ultrasound combined with transluminal Omni View three-dimensional ultrasound for female pelvic floor dysfunction diseases was 0.931. Conclusion Intelligent pelvic floor ultrasound combined with OmniView 3 D ultrasound in female pelvic floor dysfunction diseases can effectively reflect individual pelvic structure and physiological function, with a high detection rate and high diagnostic value.
    Therapeutic Effect of Qinlian Yuyang Decoction Combined with NSAIDs on Duodenal Ulcer
    LI Yan-su
    2024, 42(10):  9-13. 
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    Objective To investigate the therapeutic effect of Qinlian Yuyang decoction combined with non steroidal anti-inflammatory drugs (NSAIDs) on duodenal ulcer and its effect on pepsin Ⅰ (PG Ⅰ) and human β2 defensin 2 (HBD-2). Methods Selected 80 duodenal ulcer patients admitted to Gansu Baiyin Central Hospital from August 2020 to May 2023, and randomly divided into observation group and control group, 40 cases in each group. The control group was treated with conventional quadruple therapy and ibuprofen for analgesia, while the observation group was treated with Qinlian Yuyang Decoction on the basis of the control group. The clinical efficacy of the two groups were compared, the changes of TCM syndrome score before and after treatment were compared, and the expression levels of PG Ⅰ and HBD-2 were compared. Results The total effective rate of the observation group was significantly higher than that of the control group (P<0.05). Before treatment, there was no significant difference in the TCM syndrome scores related to wrist abdominal pain or fullness, nausea, stupidity, short yellow urine, dry mouth, and bitter mouth between the two groups (P>0.05). After treatment, the TCM syndrome scores related to wrist abdominal pain or fullness, nausea, stupidity, short yellow urine, dry mouth, and bitter mouth in the two groups decreased, and the observation group was lower than the control group (P<0.05). There was no significant difference in the levels of PG Ⅰ and HBD-2 between the two groups before treatment (P>0.05). After treatment, PGI and HBD-2 levels were reduced in both groups, and the observation group was lower than the control group (P<0.05). Conclusion Qinlian Yuyang decoction combined with NSAIDs has a significant therapeutic effect on duodenal ulcer, which can reduce the clinical symptoms, reduce inflammatory reaction and improve gastrointestinal function.
    Analysis of the Correlation Between Outdoor Activities at Home and Respiratory Tract Infections in Children Aged 3~6 Years Old
    YANG Fan
    2024, 42(10):  13-15. 
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    Objective To explore the correlation between outdoor activities at home and the incidence of respiratory infections in children aged 3~6 years old. Methods A total of 6592 children with respiratory tract infections admitted to our hospital from May 2022 to May 2023 were selected as the study subjects, and 1000 healthy children who came to our hospital for physical examination during the same period were selected as the control group. Investigate the outdoor activity time and living environment of all children, and conduct comparative analysis. Investigate the outdoor activity situation of two groups of children in different weather conditions, and use logistic regression analysis to analyze the relationship between outdoor activity time at home, living environment, different weather activities, and the occurrence of respiratory tract infections. Results There was no significant difference between the two groups of children in terms of noise levels within 100m of their homes (P>0.05). There were significant differences between the two groups of children in terms of outdoor activity time at home, odorous water ditches within 100 m of their homes, garbage stations within 100 m of their homes, and the distance between their homes and the main transportation line (P<0.05). There was a significant difference in the comparison of outdoor activities in hot weather, rainy weather, and other extreme weather between the two groups of children (P<0.05). The results of logistic regression analysis indicate that outdoor activities at home, as well as the distance between home and the main transportation line, outdoor activities in hot weather, and other extreme weather outdoor activities, are independent influencing factors for the occurrence of respiratory infections (P<0.05). Conclusion There is a significant relationship between the duration of outdoor activities at home and the incidence of respiratory infections in children aged 3~6 years old. Moreover, if the distance from home to odorous ditches and main transportation lines is too close, or if outdoor activities increase in hot weather or other extreme weather conditions, the incidence of respiratory infections will also increase.
    Effect of Fendong Combined with Kuntai Capsule on Perimenopausal Syndrome and its Influence on 5-HT, NE and DA Levels
    MENG Yu-mei
    2024, 42(10):  20-23. 
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    Objective To investigate the efficacy of Fendong combined with Kuntai capsule in the treatment of perimenopausal syndrome and its influence on the levels of 5-hydroxytryptamine (5-HT), norepinephrine (NE) and dopamine (DA). Methods From March 2020 to May 2022, 80 patients with perimenopausal syndrome were divided into two groups with 40 cases in each group by random number table method.The control group was treated with fenmorton, and the experimental group was treated with Fenmorton combined with Kuntai capsule. The clinical efficacy and safety were evaluated. The levels of sex hormones [Estradiol (E2), follicle-stimulating hormone (FSH), luteinizing hormone (LH)] and neurotransmitters [5-HT, NE, DA] were detected before and after treatment. Results The total response rate in the test group (97.50%) was significantly higher than that in the control group (80.00%) (P<0.05). The E2 level in the post-treatment group was significantly lower than that in the control group (P<0.05), and the FSH and LH levels in the two groups (P>0.05). NE and DA levels in the posttreatment test group were significantly higher than those in the control group (P<0.05), and there was no difference in 5-HT levels between the two groups (P>0.05). Conclusion The treatment of perimenopausal syndrome has good curative effect, safe and reliable, and can effectively improve E2 level and neurotransmitter level.
    The Effect of Bilateral Nasal Covering Method on Short-term and Long-term Stereovision in Children with Esotropia and Anisometropia
    JIN Li-hong, LU Yong-jun
    2024, 42(10):  36-39. 
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    Objective To investigate the effects of bilateral nasal covering on short-term and long-term stereovision in children with esotropia and anisometropia. Methods From May 2019 to May 2022, 60 cases of children (120 eyes) with esotropia and anisometropia who were diagnosed and treated at Hancheng People's Hospital were selected. Accorded to the principle of random envelope drawing, the children were divided into two groups with 30 cases in each group. The study group was treated with bilateral nasal covering therapy, while the control group was treated with alternating covering therapy. Two groups were observed for 3 months for covering therapy. Record the recent and long-term changes in stereoscopic vision, total effective rate, and strabismus of the two groups of children, and follow up the recurrence rate of the patients. Results The treatment effect of the study group was significantly better than that of the control group after 3 months of treatment (P<0.05). After 3 months of treatment, the strabismus of the study group and the control group were lower than before treatment (P<0.05), while the study group was lower than the control group (P<0.05). After 3 months of treatment, compared to the proportion of central foveal stereopsis in the control group, that in the study group were higher (P<0.05), while compared to the proportion of peripheral stereopsis in the control group, that in the study group was lower (P<0.05). After 3 months of treatment, the recurrence rates of the study group were lower than the control group (P<0.05). Conclusion The application of double nasal side covering method in children with esotropia and anisometropia can improve short-term and long-term stereoscopic vision, promote the reduction of strabismus, improve treatment effectiveness, and also reduce the recurrence rate of strabismus in children.
    Effect of Vitamin C Combined with Cimetidine on Prognosis Related Indicators and Allergen and Kidney Damage in Children with Henoch Schonlein Purpura
    LIU Fang, ZHANG Min, WU Hong-bo, YAN Ting-ting
    2024, 42(10):  39-43. 
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    Objective To investigate the effect of vitamin C combined with cimetidine on the prognosis of children with Henoch Schonlein purpura and the impact on allergens and kidney damage. Methods A total of 80 cases of children with Henoch Schonlein purpura in Shuyang hospital from January 2020 to December 2022 were selected and analyzed. They were divided into observation group and control group by lottery, with 40 cases in each group. The control group received conventional symptomatic treatment. The observation group was treated with vitamin C combined with cimetidine on the basis of the control group. The levels of interleukin-18 (IL-18), D-Dimer (D-D) and fibrinogen (FIB) related prognostic indicators in the two groups were compared, and the positive rates of allergen specific IgE antibodies in the two groups were detected before and after treatment, and the expression levels of urine routine related renal damage indicators in the two groups were compared before and after treatment. Results There was no significant difference in the levels of IL-18, D-D and FIB related prognostic indicators between the two groups before treatment (P>0.05). After treatment, the levels of IL-18, D-D and Fib in the two groups decreased, and the observation group was lower than the control group (P<0.05); There was no significant difference in the positive rate of IgE antibody between the two groups(P>0.05). After treatment, the positive rate of allergen specific IgE antibody in the observation group was lower than that in the control group(P<0.05); There was no significant difference in the levels of urinary white blood cells, urinary red blood cells and positive rate of urinary protein between the two groups before treatment (P>0.05). After treatment, the levels of urinary white blood cells, urinary red blood cells and positive rate of urinary protein in the two groups were reduced, and the observation group was lower than the control group (P<0.05). Conclusion Vitamin C combined with cimetidine can significantly improve the prognosis of children with Henoch Schonlein purpura, reduce the positive rate of allergen specific IgE antibody detection, and reduce the degree of renal damage.
    Aspirin Combined with Low Molecular Heparin Calcium on the Application Effect of Limited Fetus and the Impact on the Ending of Pregnant Women
    SHI Fang-fang, PAN Lei-lei
    2024, 42(10):  43-46. 
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    Objective To analyze the efficacy of aspirin combined with low molecular weight heparin calcium in the treatment of fetal growth restriction and its impact on umbilical artery blood flow parameters and delivery outcomes, in order to improve fetal intrauterine restriction and maternal and fetal delivery outcomes. Methods 70 pregnant women with fetal growth restriction admitted to Youyang Hospital of Chongqing Youyang County People's Hospital (starting from May 2020 to May 2021) were selected for this clinical practice study. The patients were divided into groups using a single and double number method, with 35 cases per group.The treatment drug in the study group was aspirin combined with low molecular weight heparin calcium, while the control group was low molecular weight heparin calcium. The comparison was made before and after treatment The levels of umbilical artery blood flow parameters including pulsatile index (PI), resistance index (RI), peak systolic/diastolic(S/D), developmental indicators such as head circumference, femoral length, body weight, biparietal diameter, total effective rate of treatment, and incidence of adverse maternal and fetal delivery outcomes) in the last two groups of fetuses. Results After treatment, the levels of fetal umbilical artery blood flow parameters (including PI, RI, S/D) in the study group were significantly lower than those in the control group. The levels of developmental indicators such as fetal head circumference, abdominal circumference, femoral length, and femoral length in the study group were significantly higher than those in the control group. The total effective rate of treatment in the study group was significantly higher than that in the control group, and the incidence of adverse delivery outcomes in the study group was significantly lower than that in the control group. The comparison between the two groups was statistically significant (P<0.05). Conclusion The use of aspirin combined with low molecular weight heparin calcium in the treatment of fetal growth restriction can achieve good therapeutic effects. It can not only effectively improve fetal umbilical artery blood flow parameters and promote good fetal growth and development, but also reduce the incidence of adverse delivery outcomes for mothers and infants, there by improving the prognosis of mothers and infants. It is worth clinical application and promotion.
    Clinical Study of Lateral Decubitus DAA Direct Anterior Approach and Posterolateral Hip Approach Total Hip Arthroplasty in the Treatment of Femoral Neck Fracture
    XU Jiang-lin
    2024, 42(10):  46-49. 
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    Objective To compare the effect of using lateral decubitus DAA direct anterior approach and posterolateral hip approach during total hip replacement, and find a suitable surgical approach for patients with femoral neck fracture. Methods A total hip arthroplasty was used to divide 70 patients with femoral neck fracture admitted to our hospital from June 2022 to June 2023 as the research subjects, and the patients were divided into two groups by random number table method (named by observation group and control group, respectively).All patients underwent total hip replacement. Results The intraoperative blood loss volume (217.56±20.94) mL and postoperative incision pain score (2.06±0.34) in the observation group were lower than that in the control group (298.29±24.85) mL and (5.92±1.08) points, the postoperative drainage (420.29±30.42) mL in the observation group was higher than that in the control group (310.35±24.76) mL, and the hospitalization time of the observation group (5.14±1.03) was shorter than that in the control group (8.25±1.48)d, the incidence of postoperative complications (2.86%) in the observation group was lower than that in the control group (11.43%), and the difference between the two groups was significant and statistically significant (P<0.05). Conclusion Compared with the posterolateral hip approach, the direct anterior approach of lateral DAA in total hip replacement in patients with femoral neck fracture is more effective, which causes less damage to the patient's body, causes less postoperative pain, and ensures adequate drainage and faster postoperative recovery.
    The Concept of "Preventive treatment of disease" through the Application and Thinking of Health Management in the Whole Life Cycle
    WU Yong-rong, LAN Hong-qin, SUN Gui-xiang, YE Xin-ping, ZHANG Zhi, WANG Wei, LI Ling, YANG Ji-chang
    2024, 42(10):  65-69. 
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    The proposal of the whole life cycle health management is based on the current situation of the transformation of the disease spectrum of the Chinese population to non-communicable chronic diseases. The concept of "prevention before disease" is the primary link of the idea of treating disease without disease, with the important connotation of "health without disease, prevention before disease" and the main purpose of blocking the source of disease, which is in line with the implementation of the strategy of "healthy China". It is of great significance for disease prevention to apply the concept of "prevention before disease" in the whole life cycle management. Therefore, the idea of treating diseases should be applied in the whole life cycle health management actions of people in different periods of "the fetal yuan period when the two sperm are compatible, the infantile period when the young Yin and Yang are young, the adolescence when the muscles and bones are full, the prime period when the old age is exhausted, and the dying period when the qi and blood essence are weak", and standardized, reasonable and feasible health management means should be formulated according to the people in different periods. It will help prevent and reduce the occurrence of diseases in different populations in different periods, improve the health and happiness of the people, and have a positive guiding significance for the realization of the healthy China strategy. This paper will take the "health intervention strategy of the whole life cycle" as the key point, sort out the physiological characteristics of healthy people in different periods, and propose targeted health management elements according to different periods of people, in order to build a systematic awareness of traditional Chinese medicine health management and help promote the strategy of "Healthy China Action".
    On the Dual Cultural Value of Traditional Medicinal Plants from the Perspective of Same Origin of Medicinal Dyeing
    ZHENG Hong-mei, LIU Qing, KANG Qi
    2024, 42(10):  69-71. 
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    With the revival of traditional culture and the development of green and environmentally friendly economy in recent years, plant printing and dyeing techniques have once again returned to the public's view. As a branch of plant dyeing, traditional medicinal plant dyeing can not only give clothing and fabrics a simple and soft beauty, but also have the health function of cultivating the body and mind, with dual cultural values of dyeing and medicine.
    Overview of the Development and Research of Training Models for Robot Surgery Medical Personnel in China
    CHENG Xue, CHEN Xue-li, WANG Fei
    2024, 42(10):  72-74. 
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    Robotic surgery can provide surgeons with more precise and minimally invasive options, so its treatment results are more precise. In recent years, the technology of robot-assisted endoscopy is becoming more and more mature, and the surgical methods are becoming more complicated and personalized. The education and training effect and current situation of robot-operated medical personnel are also worthy of discussion and research. At present, many hospitals or universities have set up robot surgery training courses to improve the practical and practical of relevant medical personnel, and attach importance to the assessment and safety supervision of relevant personnel skills, so as to further promote the development of robot technology. Based on this, this study summarized and analyzed the development and application status of the training mode of medical personnel in robotic surgery in China.
    Research on the Cognitive Status and Influencing Factors of Osteoporosis in the Elderly in the Community of Fuyang City
    YIN Jun, RUAN Fei-fei, ZHU Zi-yuan, LU Ai-min, WU Fei
    2024, 42(10):  86-89. 
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    Objective To investigate the current status of knowledge about osteoporosis in the elderly in Fuyang City, and to explore its influencing factors. Methods A questionnaire was conducted on 220 elderly people in the community using general information questionnaire and osteoporosis related knowledge questionnaire. Results The knowledge about osteoporosis in the elderly in the community was relatively lacking. The results of multiple linear regression analysis showed that age, body mass index, family history of osteoporosis, and diseases affecting bone metabolism were important influencing factors of osteoporosis in the elderly in the community (P<0.05). Conclusion Interventions should be actively taken according to the actual situation of the elderly to achieve early prevention, early detection and early treatment, so as to prevent and delay the occurrence of osteoporosis.
    The Application Effect of A New Health Education Model in High-quality Nursing of Thoracic Surgery
    YI Hai-ling
    2024, 42(10):  96-99. 
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    Objective To analyze the application effect of a new health education model in high-quality nursing of thoracic surgery. Methods Sixty patients undergoing thoracic surgery admitted to our hospital from May 2022 to April 2023 were selected and divided into a study group and a control group using a lottery method, with 30 patients in each group. The control group provided high-quality care, while the research group combined Teachback health education and internet platform models. Compare the self-care ability, quality of life, psychological status, and treatment compliance of two groups of patients after nursing care. Results The self-care ability and quality of life of the study group were significantly higher than those of the control group (P<0.05); The self-evaluation scores of depression and anxiety in the study group were significantly lower than those in the control group (P<0.05); The treatment adherence of the study group was significantly higher than that of the control group (P<0.05). Conclusion The new health education model in high-quality nursing of thoracic surgery is beneficial for improving patients' self-care ability and quality of life, alleviating psychological pressure, and improving treatment compliance, which is worthy of clinical application.
    Comparative Study on the Clinical Effect of Percutaneous Transforaminal TESSYS Technique and Posterior Fenestration of the Laminae Nucleus Pulposus
    GONG Wei-xing, REN Xiao-xuan, Yan Hu
    2024, 42(10):  159-162. 
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    Objective To explore and analyze the comparative study of surgical efficacy and imaging changes between percutaneous transforaminal endoscopic TESSYS technology and posterior laminectomy for nucleus pulposus. Methods According to different surgical procedures, 90 patients receiving lumbar discectomy admitted to Tai 'an Hospital of Traditional Chinese Medicine from May 2020 to June 2022 were divided into 45 patients in each group. The observation group was given percutaneous transforaminal TESSYS technology, while the control group was given posterior fenestrated laminae nucleus pulposus extraction. The therapeutic effects of the two groups were compared. Results Compared with the control group, the observation group had less intraoperative blood loss, shorter incision length, lower postoperative VAS score, lower nerve root injury rate, lower recurrence rate at 1 year follow-up, and lower incidence of lumbar instability and adjacent segment degeneration after 1 year follow-up, with statistical significance (P<0.05). There was no significant difference in the excellent and good rate of improved Macnab between the two groups (P>0.05). Conclusion The clinical effect of percutaneous lumbar discectomy using TESSYS technology under intervertebral foramen is significant for the treatment of lumbar disc herniation. The incision is small, the damage to surrounding tissues is small, the pain is mild, and the short-term follow-up imaging performance is good, which can promote prognosis.
    The Efficacy and Safety of Anlotinib Following Second-Line Chemotherapy for Extensive Stage Small-Cell Lung Cancer
    ZHENG Jian-ping, CUI Tong-jian
    2024, 42(10):  163-166. 
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    Objective This study aims to evaluate the efficacy and safety of anlotinib hydrochloride capsules in broad-stage small cell lung cancer(SCLC) patients that have received conventional secondary chemotherapy but still received no effective control, to study the efficacy and safety of this drug in broad-stage SCLC with conventional secondary chemotherapy but still no effective control. The primary outcome measures were time to no disease progression (PFS) and overall survival (OS). Methods A total of 13 extensive stage SCLC patients were selected who were reated at Fujian provincial hospital medical oncology from May 2018 to October 2018. Among these patients,progression or advers reactions after chemotherapy happened, with PS 0-2 points. the standard dose anlotinib treatment were given to them,and if patients suffered from intolerance advers reactions ,the dose of anlotinib can be reduced.The observation and analysis of anlotinib for second-line treatment of extensive SCLC were done for evaluation of drug efficacy and safety. The primary study endpoints were PFS and OS, and the secondary study endpoints were NSE level and safety of anlotinib,so as to provide the corresponding clinical basis for the promotion and application of anlotinib. Results After two to six cycles of treatment, we found that the mPFS of anlotinib was 5.2 months (95%CI 5.0~5.4); mOS 7.0 months. NSE decreased with anlotinib. Although the overall proportion of side effects reached 75%, only the proportion of grade 3/4 side effects was 5%. Conclusion Anlotinib is a treatment for SCLC that controls the development of the disease and has some efficacy; Third-line treatment of SCLC with anlotinib can significantly improve PFS and OS and has strong safety and good tolerability.
    Study on the Effect of Pharmacist Online Guidance in the Prevention and Relapse of External Hemorrhoids
    CAI Wei-hua
    2024, 42(10):  170-173. 
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    Objective Observing the recurrence of external hemorrhoids in patients under the intervention of pharmacists, in order to explore the application value of online guidance of pharmacists in the prevention and treatment of external hemorrhoids. Methods A total of 108 patients diagnosed with external hemorrhoids who visited Qinzhou Second People's Hospital from January 2018 to June 2022 wree selected as research subjects.According to coin toss, the patients were randomly divided into two groups: control group (54 cases) and observation group (54 cases).The control group was treated with routine local medication in the anorectal department, while the observation group received daily guidance from clinical pharmacists online through the internet on the basis of routine treatment in the control group, including dietary guidance, medication preparation guidance, and lifestyle guidance.The recurrence rate, the average days of illness, the recovery time after treatment and the drug expenses were compared between the two groups. Results After intervention by clinical pharmacists, the recurrence rate of hemorrhoids in the observation group (33.33%) was significantly lower than that in the control group (68.52%) within 2 years, with a statistically significant difference (P<0.05).In the observation group, the number of days of illness, the recovery time and the cost of treatment drugs were significantly lower than those in the control group.Moreover, the incidence days, rehabilitation time, and treatment drug costs of patients who experience recurrence of the disease in the observation group were significantly lower than before the intervention, with statistically significant differences (P<0.05). Conclusion In the prevention and treatment of external hemorrhoids recurrence, clinical pharmacists provide online guidance to improve patients' awareness of the disease and compliance with prevention and treatment, which can effectively prevent hemorrhoids recurrence and significantly reduce the recurrence rate of patients.
    Efficacy of Ultrasonic Atomization Combined with rhEGF Eye Drops and Its Effects on Inflammatory Factors
    WANG Hong-yan
    2024, 42(10):  186-189. 
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    Objective Explore the intervention value of ultrasound nebulization combined with recombinant human epidermal growth factor (rhEGF) eye drops in patients diagnosed with dry eye syndrome, and explore the effectiveness of combined therapy in reducing tear inflammatory factor levels in patients. Methods 80 patients with dry eye who received treatment at General Western Airlines Hospital from August 2020 to January 2023 were selected as the study subjects. They were randomly divided into the study group (n=40, receiving ultrasound nebulization combined with rhEGF treatment) and the control group (n=40, receiving rhEGF treatment alone) using a random number table method. The treatment effects of the two groups were compared, including tear film break-up time (BUT), tear secretion length, and corneal fluorescence staining (FL) scores, immunological indicators of interleukin-6 (IL-6) and tumor necrosis factor- α (TNF- α) , and subjective symptom scores between the two groups of patients before and after treatment. Results The total effective rate of intervention in the study group was 97.50%, which was higher than 85.00% in the control group (P<0.05); After treatment, the BUT level of the study group patients was higher than that of the control group, and the tear secretion length and corneal FL score were lower than those of the control group (P<0.05); IL-6 and TNF- α levels of patients in study group was significantly lower than that of the control group after treatment (P<0.05); The self-conscious symptom score of the study group patients after treatment was lower than that of the control group (P<0.05). Conclusion Ultrasound atomization combined with rhEGF has a good therapeutic effect on dry eye syndrome, which can promote tear film stability, reduce tear secretion and corneal damage, and also help improve the patient's inflammatory state and improve their self symptom score. It has certain promotion and application value.