Table of Content

01 May 2024, Volume 42 Issue 9

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Investigation and Analysis of Perception and Need of Pelvic Floor Rehabilitation in Women of Childbearing Age

XUE Meng-ting, LI Xue-ming, YANG Xiao-qing, LI Jing, CHEN Qian-qian, LUO Jia

2024, 42(9):  1-4. 

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Objective To investigate and analyze the perception and demand of postpartum pelvic floor rehabilitation in women of childbearing age, and to explore the influencing factors, so as to provide the basis for clinical pelvic floor rehabilitation. Methods A self-designed survey on women of childbearing age was conducted to investigate their understanding of pelvic floor dysfunction and rehabilitation knowledge, demand and factors affecting their selection of rehabilitation treatment. Results Among women of childbearing age, 14.16% had pelvic floor dysfunction, 27.43% had no pelvic floor dysfunction and 58.41% had no examination and did not know. Most have heard of postpartum pelvic floor rehabilitation, but have not performed postpartum pelvic floor rehabilitation. About pelvic floor rehabilitation knowledge, the demand for life precautions was 87.61%. 42.48% of people are unclear about what pelvic floor rehabilitation treatment is among the factors affecting rehabilitation exercise. Conclusion Women of childbearing age have less knowledge about pelvic floor rehabilitation and “not knowing what pelvic floor rehabilitation is” is a major barrier to treatment.

Analysis of the Therapeutic Effect of Platelet Rich Plasma Combined with Isokinetic Muscle Strength Training on Knee Osteoarthritis and Cartilage

LYU Xi-yan, REN Chao-zhan, XU Jian-cheng, JI Jing

2024, 42(9):  4-7. 

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Objective To observe the therapeutic effect of platelet-rich plasma combined with isokinetic muscle strength training on knee osteoarthritis and the changes in cartilage thickness. Methods Sixty eligible knee osteoarthritis patients admitted to the Gansu Provincial Hospital of Traditional Chinese Medicine from October 2021 to September 2023 were randomly divided into a control group of 32 cases and a observation group of 28 cases. The control group was treated with sodium hyaluronate injection combined with conventional muscle strength training, while the observation group was treated with autologous platelet-rich plasma injection combined with isokinetic muscle strength training. Western Ontarioand McMaster University Osteoarthritis Index (WOMAC) evaluation was performed on patients before treatment and 4 weeks and 6 months after treatment. The peak torque (PT) of the 60°/s and 90°/s extensor muscles on the affected knee joint was evaluated using an isokinetic muscle strength testing system, and the average thickness of the patient's articular cartilage was evaluated using an ultrasound diagnostic instrument. Results After 4 weeks and 6 months of treatment, the WOMAC score and isokinetic measurements of knee extensor muscles at 60°/s and 90°/s in both groups were better than before treatment (P<0.05). Compared between the two groups, the observation group showed better results than the control group (P<0.05). After 6 months of treatment, the average knee cartilage thickness in the observation group was better than before treatment and the control group (P<0.05). Conclusion The combination of platelet-rich plasma and isokinetic muscle strength training can effectively improve knee joint function, extensor muscle strength, and protect joint cartilage in patients with knee osteoarthritis.

Observation on Clinical Effect of Xiaoqinglong Decoction combined with Western Medicine in Treating Phlegm-Dampness Lung Syndrome in Acute Exacerbation of COPD

NI Xun-qing, ZHANG Xin-wei, CHEN Xiang-jun, SONG Wen-cai, SHEN Qi-ming

2024, 42(9):  7-12. 

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Objective To observe the clinical effect of Xiaoqinglong Decoction combined with Western medicine in the treatment of phlegm-dampness lung syndrome of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods A total of 80 patients with AECOPD syndrome of phlegm-dampness and lung retention admitted to the Linyi Hospital of Traditional Chinese Medicine from January 2022 to December 2022 were selected and divided into two groups according to random number table method, 40 cases in each group. Both groups were treated with conventional treatment, and the observation group was treated with supplemented Xiaoqinglong decoction on the basis of conventional western medicine treatment. Calculate the clinical efficacy of two groups,the cough relief time, asthma disappearance time and wheezing noise disappearance time of the two groups were observed. Levels of serum tumor necrosis factor-α (TNF-α), peripheral blood interleukin-6 (IL-6), hypersensitive C-reactive protein (hs-CRP), forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), and percentage of forced expiratory volume in the first second to forced vital capacity (FEV₁/FVC) before and after treatment. Results The cough relief time, asthma disappearance time and wheezing sound disappearance time in observation group were shorter than those in control group (P<0.05). After treatment, the serum levels of TNF-α, IL-6 and hs-CRP in the two groups were lower than before treatment, and the observation group was lower than the control group (P<0.05). After treatment, the levels of FVC, FEV₁ and FEV₁/FVC in the two groups were improved compared with those before treatment, and the observation group was higher than the control group (P<0.05). The total effective rate of the observation group was significantly better than that of the control group (P<0.05). Conclusion Xiaoqinglong Decoction can inhibit the expression of inflammatory factors, reduce airway resistance, promote airway unobstruction, improve clinical symptoms and lung function, and improve clinical efficacy in treating AECOPD syndrome of phlegm dampness and lung accumulation.

The Clinical Efficiency of Jindan Paishi Decoction in Treating Patients with Damp-Heat Type of Ureteral Calculus

SUN Tao, CAI Ke, LIU Zi-shan, ZOU Chun-li, SIN Long-jun

2024, 42(9):  12-16. 

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Objective This study aims to explore the clinical efficiency of Jindan Paishi (JDPS) decoction in treating patients with damp-heat type of ureteral calculus. Methods Total of 62 patients of ureteral calculus with damp -heat syndrome were hospitalized in Peoples' Hospital of Pingyi County from Jan 2021 to Dec 2022. According to randomized digital table method, all patients were randomly divided into treatment group (n=31) orally treated with JDPS decoction and control group (n=31) orally given Shenshitong granules for 30 days continuously. The pain degrees of patients were evaluated according to WHO Pain Grade. The traditional Chinese medicine (TCM) syndromes, micturition frequency and urine volume were recorded. The number of WBC and RBC in urine, the WBC classification and numbers in blood, creatinine and urea nitrogen were determined by biochemical assay. The size and number of ureteral calculus were detected by imaging examination, and at last the total effective rate of the two drugs was evaluated comprehensively. Results After treatment, all the pain degree and pain time, the tongue coating color and pulse conditions, the size and number of ureteral calculus, the urine volume and times of patients were significantly improve than those before treatment respectively; the size and number of ureteral calculus were significantly reduced than those before treatment; the numbers of WBC and RBC in urine were significantly decreased than those before treatment; the creatinine (Cr) and urea nitrogen (BUN) levels in serum were significantly decreased than those before treatment; the numbers of blood WBC was significantly reduced while the neutrophils and lymphocytes increased than those before treatment(P<0.05). The pain degree and time of patients in treatment group were significantly decreased than those in control group(P<0.05); the number of WBC in urine,the number of RBC,the serum levels of Cr and BUN, and the number of WBC in blood in treatment group were significantly lower than those in control group(P<0.05). The total effective rate of patients in treatment group (90.32%) was significantly higher than that in control group (80.64%)(P<0.05). Conclusion sJDPS decoction might improve clinical symptoms and renal function of patients with damp-heat type of ureteral calculus, and enhance the anti-inflammatory effect of blood WBC.

Correlation and Prognostic Prediction of PECAM-1, Ventricular Remodeling, and Severe Heart Failure after Coronary Intervention in Acute Myocardial Infarction

CHEN Rong-hong

2024, 42(9):  17-20. 

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Objective To investigate the correlation between platelet endothelial cell adhesion molecule-1 (PECAM-1), ventricular remodeling and severe heart failure after coronary intervention in patients with acute myocardial infarction, and the prognostic value. Methods A total of 80 patients with heart failure after coronary intervention in acute myocardial infarction admitted to our hospital from May 2020 to May 2023 were selected as the research subjects. The severity of heart failure in patients was evaluated using Killip grading and grouped into a Grade Ⅰ group of 16 cases, a Grade Ⅱ group of 23 cases, a Grade Ⅲ group of 20 cases, and a Grade Ⅳ group of 21 cases. In addition, 30 healthy volunteers who came to our hospital for physical examination during the same period were selected as the control group. Compare the levels of PECAM-1 and ventricular remodeling indicators in five groups of patients, and use Spearman correlation analysis to analyze the correlation between PECAM-1, ventricular remodeling, and severe heart failure after coronary intervention in acute myocardial infarction. Subsequently, 80 patients with heart failure after coronary intervention in acute myocardial infarction were divided into a death group (n=20) and the remaining patients into a survival group (n=60). The clinical general situation of the two groups of patients was compared, and the predictive value of PECAM-1 and ventricular remodeling on the prognosis of heart failure after coronary intervention in acute myocardial infarction was analyzed. Results The PECAM-1 and LVMI levels in grade IV patients were significantly higher than those in grade III, II, I, and control groups, while LVRI levels were lower than those in grade III, II, I, and control groups (P<0.05); Spearman correlation analysis showed that PECAM-1 and LVMI were positively correlated with severe heart failure after coronary intervention in acute myocardial infarction, while LVRI was negatively correlated with severe heart failure after coronary intervention in acute myocardial infarction (P<0.05); There were significant differences in Killip grade, comorbidities with old myocardial infarction, PECAM-1, LVRI, and LVMI levels between the survival group and the death group (P<0.05); The results of logistic regression analysis showed that PECAM-1 (OR=2.458, 95%CI:1.359~3.257), LVRI (OR=2.546, 95%CI:1.364~3.475), LVMI (OR=2.774, 95%CI:1.876~4.010) were independent predictive indicators of heart failure after acute myocardial infarction intervention (P<0.05). Conclusion PECAM-1, ventricular remodeling, and severe heart failure after coronary intervention in acute myocardial infarction are significantly correlated, and can predict the prognosis of severe heart failure after coronary intervention in acute myocardial infarction through PECAM-1 and ventricular remodeling.

Effect of Qishao Hunaorongjin Capsule Combined with Acupuncture on Acute Cerebral Infarction and Its Influence on Long-Term Nerve Function

WANG Xiu-ping

2024, 42(9):  24-27. 

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Objective To explore the therapeutic effect of Qishao Hunaorongjin Capsule combined with acupuncture on acute cerebral infarction and its influence on long-term nerve function. Methods A total of 92 patients with acute cerebral infarction admitted to our hospital from October 2020 to October 2022 were selected as the research subjects. They were divided into an observation group and a control group using a random number table method, with 46 patients in each group. The control group underwent conventional thrombolytic therapy, and the observation group added Qipabao rongjin capsule combined with acupuncture, compared the clinical efficacy of the two groups, the long-term neurological function before and after treatment, and the quality of life. Results The total response rate in the observation group was higher than that in the control group (P<0.05). Analysis of NIHSS and MMSE scores before, 3 months and 6 months after treatment in both groups, Different treatment measures have reciprocal effects with temporal factors, All were statistically significant (P<0.05), at 3 months after the treatment, The NIHSS score of the observation group was lower than that of the control group, and the MMSE score was higher than that of the control group. After 6 months of treatment, the NIHSS score of the observation group was lower than that of the control group, and the MMSE score was higher than that of the control group(P<0.05). There was no significant difference of the two groups (P>0.05), post-treatment, The QoL scores were elevated in both groups, And the correlation score of the observation group was higher than that of the control group (P<0.05). Conclusion On the basis of conventional treatment, Qishao Hunaorengjin capsule combined with acupuncture and moxibustion has a significant therapeutic effect on acute cerebral infarction, reducing neurological damage, and improving the quality of life of patients after treatment.

The Application Effect of Xuezhikang Capsule Combined with Pravastatin Sodium Tablets on Elderly Patients with Chronic Heart Failure after Acute Myocardial Infarction and Its Impact on Neuroendocrine Factors

LIU Yan, HOU Cong

2024, 42(9):  28-31. 

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Objective To explore the application effect of Xuezhikang Capsule combined with pravastatin sodium tablets on elderly patients with chronic heart failure after acute myocardial infarction and its impact on neuroendocrine factors. Methods Eighty patients with chronic heart failure after acute myocardial infarction admitted to Chuiyangliu Hospital in Beijing from June 2022 to April 2023 were selected for study. They were divided into three groups by lot drawing, namely, control group (n=30), observation group A (n=25) and observation group B (n=25). After giving conventional treatment to the control group, observe the patients in group A to add pravastatin sodium tablets on the basis of the control group, and increase the oral administration of Xuezhikang Capsule on the basis of observation group A. The clinical efficacy of the three groups of patients was compared, and the levels of B-type natriuretic peptide (BNP), plasma renin (PRA), Aldosterone (ALD), and angiotensin Ⅱ (Ang Ⅱ) related endocrine factors were compared with the changes of left ventricular Ejection fraction (LVEF), left ventricular end systolic volume (LVESV), and left ventricular end diastolic volume (LVEDV) related cardiac function indexes. Results The total effective rate of Group B was significantly higher than that of the control group and Group A, and Group A was higher than the control group (P<0.05); After treatment, the levels of BNP, PRA, ALD, and Ang II in the three groups of patients decreased, and the observation group B was lower than the control group and observation group A, while the observation group A was lower than the control group (P<0.05); After treatment, the LVEF of the three groups of patients increased, and Group B was observed to be higher than the control group and Group A. Group A was observed to be higher than the control group, while LVESV and LVEDV decreased. Group B was observed to be lower than the control group and Group A, and Group A was observed to be lower than the control group (P<0.05). Conclusion The combination of Xuezhikang Capsule and Pravastatin Sodium Tablets has a significant therapeutic effect on elderly patients with chronic heart failure after acute myocardial infarction, and can reduce the levels of neuroendocrine factors and improve heart function, which is worthy of clinical application.

Analysis of the Effectiveness of Anatomical Steel Plate Internal Fixation System and Reconstruction Steel Plate Fixation in the Treatment of Middle Clavicle Fractures

HUANG Ning, DONG Rong

2024, 42(9):  40-43. 

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Objective To explore and analysis the effectiveness of anatomical steel plate internal fixation system and reconstruction steel plate fixation in the treatment of mid clavicular fractures. Methods From January 2019 to October 2022, 88 cases of patients with mid clavicle fractures who were admitted to a certain hospital and underwent surgical treatment were selected as the research subjects. Accorded to the 1:1 random dice rolling principle, 88 patients were divided into the anatomical group of 44 cases and the reconstruction group of 44 cases. The reconstruction group were treated with reconstruction steel plate fixation, while the anatomical group were treated with anatomical steel plate internal fixation system. The treatment effects of both groups were recorded and observed. Results There were no significant difference in intraoperative bleeding, surgical time, and incision length compared between the two groups (P>0.05). The postoperative hospital stay, incision healing time, and fracture wound healing time in the anatomical group were significantly reduced compared to the reconstruction group (P<0.05). The incidence rates of subacromial impingement sign, implant loosening, shoulder arthritis, incision infection, venous thrombosis and other complications 3 months after surgery in the anatomical group were 4.55%, and 20.45% in the reconstruction group. Compared with the reconstruction group, the incidence of complications in the anatomical group were significantly lower (P<0.05). The excellent and good rate of fracture reduction quality in the anatomical group at 3 months after surgery were 97.73%, significantly higher than 84.09% in the reconstruction group (P<0.05). The overall effective rate of the anatomical group at 3 months after surgery were 95.45%, which were significantly improved by 81.82% compared to the reconstruction group (P<0.05). The Constant and Murley shoulder joint scores at 3 months after surgery in both groups were significantly higher than those on the 1st day before surgery (P<0.05), and the Constant and Murley shoulder joint scores at 3 months after surgery in the anatomical group were also significantly higher than those in the reconstruction group (P<0.05). Conclusion Compared to the reconstruction steel plate internal fixation system, The anatomical steel plate internal fixation system can promote the recovery and fracture healing of patients with mid clavicular fractures, reduce the incidence of complications, improve the quality of fracture reduction, and improve the overall efficacy and shoulder joint function of patients.

Correlation between Cerebrospinal Fluid Lysophosphatidic Acid Level and Neurological Deficit in Patients with Cerebral Infarction

JI Jing, LI Jing-chun

2024, 42(9):  44-48. 

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Objective To explore and analysis the correlation between cerebrospinal fluid lysophosphatidic acid (LPA) level and neurological deficit in patients with cerebral infarction (CI). Methods From March 2020 to November 2022,67 patients with cerebral infarction treated in Changping District Hospital of Integrated Traditional Chinese and Western Medicine in Beijing were selected as the study objects. All patients were scored with the National Institute of Health stroke scale (NIHSS) at admission, and the level of lysophosphatidic acid in cerebrospinal fluid was detected and analyzed. Results In the 67 patients, the average NIHSS score for neurological deficits were (18.32±2.15) points, with 17 cases (severe group) scoring above 21 points. There were no significant difference in gender, body mass index, education level, and comorbidities compared between the severe group and the non severe group (P>0.05). There were significant difference in age, onset to hospital admission time between the two groups (P<0.05). There were no significant difference in blood glucose, homocysteine, total cholesterol, and triglyceride levels between the two groups (P>0.05), while the low-density lipoprotein cholesterol levels in the severe group were higher than those in the non severe group (P<0.05). The level of lysophosphatidic acid in cerebrospinal fluid of severe group were significantly higher than that of non severe group (P<0.05). Pearson analysis showed that NIHSS score were positively correlated with age, time from onset to admission, and cerebrospinal fluid lysophosphatidic acid level (P<0.05). Logistic regression analysis showed that age, the time from onset to admission, and the level of lysophosphatidic acid in cerebrospinal fluid were the important factors influencing NIHSS scores in patients with cerebral infarction (P<0.05). Conclusion The neurological deficit status of patients with cerebral infarction is relatively serious. The worse the neurological deficit status of patients with cerebral infarction, the higher the level of lysophosphatidic acid in cerebrospinal fluid. The level of lysophosphatidic acid in cerebrospinal fluid of patients with cerebral infarction is related to the neurological deficit status.

Diagnostic Efficacy of Brain Natriuretic Peptide combined with Cardiac Troponin in Unstable Angina Pectoris with Chronic Heart Failure in Coronary Heart Disease and Predictive Value of Adverse Cardiovascular Events after Interventional Surgery

WANG Yuan

2024, 42(9):  48-52. 

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Objective To explore the diagnostic efficacy of brain natriuretic peptide (BNP) combined with troponin (cTnT) in unstable angina pectoris with chronic heart failure in coronary heart disease and the predictive value of adverse cardiovascular events after interventional surgery. Methods Select Tianshui first people's hospital from May 2020 to May 2023 admitted patients: 85 cases of coronary heart disease unstable angina with chronic heart failure as chronic heart failure group, 85 cases of pure coronary heart disease unstable angina without complicated chronic heart failure group as a chronic heart failure, 85 cases of healthy volunteers as a control group. Compare the expression levels of BNP and cTnT in three groups of patients, and establish a receiver characteristic (ROC) working curve to analyze the diagnostic efficacy of BNP combined with cTnT in unstable angina pectoris with chronic heart failure. Subsequently, 85 patients with unstable angina pectoris complicated by chronic heart failure who underwent PCI were divided into two groups: non MACE group (n=64) and MACE group (n=21). The clinical characteristics of the two groups of patients were compared, and the predictive value of BNP and cTnT for adverse cardiovascular events after percutaneous coronary intervention in unstable angina pectoris complicated by chronic heart failure was analyzed. Results There was a significant difference in the levels of BNP and cTnT among the three groups of subjects. The levels of BNP and cTnT in the chronic heart failure group were significantly higher than those in the non chronic heart failure group and the control group (P<0.05); The combination of BNP and cTnT is superior to a single test in the diagnosis of unstable angina pectoris with chronic heart failure in coronary heart disease (P<0.05); There was no significant difference in gender, BMI, comorbidities, drinking history, and smoking history between the non MACE group and the MACE group (P>0.05). There was a significant difference in age, cardiac function grading, left ventricular ejection fraction, TIMI score, BNP, and cTnT expression levels between the two groups (P<0.05); The results of logistic regression analysis showed that BNP and cTnT were independent risk factors for adverse cardiovascular events after intervention in unstable angina pectoris with chronic heart failure (P<0.05). Conclusion BNP combined with cTnT can improve the diagnostic efficacy of unstable angina pectoris with chronic heart failure, and BNP and cTnT are independent risk factors for the main cardiac blood events after interventional surgery for unstable angina pectoris with chronic heart failure. It is suggested that in clinical practice, patients with unstable angina pectoris and chronic heart failure complicated by elevated BNP and cTnT should take timely measures to prevent cardiovascular adverse events.

Correlation Analysis of Prostate Specific Antigen, Prostate Health Index and Clinical Pathological Characteristics of Prostate Cancer

LIU Cong, ZHOU Wen-jie, WEI Fan-jie, MAO Wei

2024, 42(9):  52-55. 

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Objective To investigate the correlation between prostate specific antigen (PSA),prostate health index (PHI) and clinicopathological features of prostate cancer. Methods A total of 80 patients with prostate cancer diagnosed by biopsy pathology in People's Hospital of Shizhong District, Leshan City from August 2020 to August 2023 were selected as the research object and divided into malignant group, and another 80 patients diagnosed with benign prostatic hyperplasia through biopsy pathology in our hospital during the same period were selected as the benign group. The tumor tissues of the two groups were detected by immunohistochemistry, the expression of prostate specific antigen (PSA) was detected, and the positive rate was compared. The prostate health index (PHI) was calculated, and the phi level was compared. Then the positive rate of PSA and phi level in patients with prostate cancer with different clinicopathological characteristics were analyzed, and the relationship between PSA, phi and clinicopathological characteristics of prostate cancer was analyzed by logistic regression analysis. Results there were significant differences in the expression levels of PSA and phi among the two groups. The positive rate of PSA and the expression level of pHi in the malignant group were significantly higher than those in the benign group (P<0.05); In 80 patients with prostate cancer, there was no significant difference in pHi level between different ages and T stages, and there was no significant difference in PSA positive rate between different ages (P>0.05). There was significant difference in pHi level between patients with different lymph node metastasis, distant metastasis, Gleason score and risk classification, and there was no significant difference in PSA positive rate between patients with different T stages, lymph node metastasis, distant metastasis, Gleason score and risk classification (P<0.05); Multivariate logistic analysis showed that T stage, lymph node metastasis, distant metastasis and Gleason score were risk factors for PSA positive expression （95%CI：1.259~2.457、1.364~3.475、1.176~4.010、1.036~2.745;P=0.030、0.023、0.016、0.005）, as shown in Table 3. Lymph node metastasis, distant metastasis, Gleason score and risk classification were the risk factors for the increase of phi level （95%CI：1.362~3.783、0.826~2.926、1.221~3.525、0.315~1.425;P=0.042、0.031、0.026、0.011）. Conclusion The PSA positive rate and PHI expression level of prostate cancer patients are significantly increased, and T stage, lymph node metastasis, distant metastasis, and Gleason score are risk factors for PSA positive expression. Lymph node metastasis, distant metastasis, Gleason score, and risk grade are risk factors for increased PHI level.

Effect of Exercise Intervention Based on Peabody Motor Development Scale on Motor Function Rehabilitation in Children with Cerebral Palsy

XUE Cai-lin, LIU Yan-fang

2024, 42(9):  65-68. 

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Objective To explore the rehabilitation effect of exercise intervention based on the Peabody motor development scale on motor function in children with cerebral palsy. Methods A total of 80 children with cerebral palsy admitted to the Yulin Gaoxin Hospital from June 2020 to November 2022 were selected as the research subjects. They were randomly divided into an observation group and a control group using a random number table, with 40 cases in each group. The control group received routine rehabilitation treatment, while the observation group received exercise intervention based on the Peabody Motor Development Scale. The total effective rate of rehabilitation treatment was compared between the two groups. The Fugl Meyer Motor Function Assessment Scale (FMA) and Gross Motor Function Test Scale (GMFM) were used to evaluate the rehabilitation level of motor function before and after treatment, and the Quality of Life Assessment Scale (PedsQIA.0) was used to evaluate the quality of life of the children, Evaluate the intelligence level of children using the Intellectual Development Index (MDI). Results The total effective rate of rehabilitation in the observation group was significantly higher than the control group (P<0.05); There was no significant difference in PDMS-2 and GMFM scores in the two groups (P>0.05), and PDMS-2 and GMFM scores in the two groups, and the observation group was higher than that in the control group (P<0.05); Before treatment, there was no significant difference in PedsQIA.0 and MDI scores between the two groups of children (P>0.05). After treatment, the PedsQIA.0 and MDI scores of the two groups of children increased, and the observation group was higher than the control group (P<0.05). Conclusion The exercise intervention based on the Peabody Motor Development Scale has a significant rehabilitation effect on children with cerebral palsy, which can improve their motor function, promote their intellectual development, and improve their quality of life.

Review of Research Progress of the Combination of Traditional Chinese and Western Medicine in Secondary Sarcopenia

DONG Xu, FENG Tao

2024, 42(9):  77-79. 

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Secondary muscular atrophy(SMA) is a common neuromuscular disease, commonly seen in middle-aged and elderly patients. The incidence of this disease is relatively high, with a decrease in muscle mass and muscle strength as the main manifestations. The etiology is complex and the clinical manifestations are diverse. At the same time, clinical doctors do not pay enough attention to this disease and fail to provide early intervention and treatment, which can ultimately seriously affect the long-term survival of patients. Although the etiology and pathological mechanism of SMA are not fully understood, significant progress has been made in the study of integrated traditional Chinese and Western medicine. This review will comprehensively introduce the research progress of the combination of traditional Chinese and Western medicine in SMA, in order to provide some reference for the diagnosis and treatment of this disease.

Current Situation and Reflection on the Inheritance of Menghe Medical School in Traditional Chinese Medicine Hall of Primary Medical and Health Institutions

XU Rui, GAO Hua, HE Jun

2024, 42(9):  80-83. 

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Menghe School of Medicine is a local school of traditional Chinese medicine with the clearest inheritance vein, the most complete discipline, the largest number of inheritors and the most widely spread in China. It has profound academic heritage and rich experience in diagnosis and treatment. However, with the development of the Times, the inheritance of traditional Chinese medicine schools such as Menghe School of Medicine is facing no small challenge. This paper investigates the current situation of the traditional Chinese medicine center of the primary medical and health institutions in Changzhou city, the birthplace of the Menghe medical School, as well as the awareness of the staff and residents of the primary medical and health institutions to the culture of the Menghe medical school, analyzes the shortcomings of the primary medical and health institutions in the construction of the culture of the Menghe medical school, and puts forward reasonable suggestions. In order to promote the high-quality inheritance and development of Menghe medical school, improve the service level of traditional Chinese medicine, and provide strong support for the construction of healthy China.

Effect of Personalized Diet Prescription and Teach Back Health Education on Disease Recurrence in Patients with Urinary Calculi in Qingyuan Area

LI Hui, ZHOU Qiu-yan, YANG Xiu-ying, TANG Yu-hong, HU Rong-sheng, CHEN Ying-yi, PAN Chu-zao

2024, 42(9):  87-90. 

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Objective To study the effect of personalized diet prescription and Teach back health education on disease recurrence in patients with urinary calculi in Qingyuan area. Methods A total of 200 patients with urinary calculi after surgery admitted to Qingyuan People's Hospital from February 2022 to February 2023 were selected as the study objects. Random number table method was used to divide them into observation group and control group, with 100 cases in each group. The control group was given routine nursing measures, and the observation group was given personalized diet and Teach back health education measures. Evaluate the effect of two nursing methods. Results After nursing, the incidence of urgent urination, frequency of urination, urinary pain and stone recurrence rate in observation group were lower than those in control group(P<0.05); The scores of drinking habits, eating habits, carbohydrate intake, calcium intake and exercise habits of the observation group were higher than those of the control group(P<0.05); The nursing satisfaction of the observation group was higher than that of the control group(P<0.05). Conclusion In patients with postoperative urinary calculi in Qingyuan area, personalized diet and Teach back health education nursing program can reduce the recurrence rate of the disease, improve the living habits of patients, improve nursing satisfaction, and have good application effects.

Application of Dynamic Emergency Nursing Based on HFMEA Concept in Patients with Sudden Cerebral Hemorrhage

JIN Jia-le

2024, 42(9):  93-96. 

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Objective To explore the clinical value of implementing dynamic emergency nursing based on the concept of healthcare failure mode and effect analysis (HFMEA) in patients with sudden cerebral hemorrhage. Methods 108 patients with sudden cerebral hemorrhage admitted to Inner Mongolia Autonomous Region People's Hospital from October 2020 to October 2022 were selected as the research subjects, and were divided into two groups according to different intervention methods. The control group (n=54) received routine emergency care, while the observation group (n=54) received dynamic emergency care based on the HFMEA concept. The time required for emergency care, cerebral hemorrhage volume, degree of neurological impairment, prognosis, and incidence of complications were analyzed for the two groups. Results Compared with the control group, the observation group had shorter onset to hospital time, initial treatment time in the emergency department, delivery time to relevant departments, and emergency treatment time (P<0.05). The observation group had less cerebral hemorrhage compared to the control group (P<0.05). After nursing, the National Institutes of Health Stroke Scale (NIHSS) scores decreased in both groups, while the Glasgow Outcome Scale (GCS) scores increased in both groups. The observed group had a more significant change compared to the control group (P<0.05). The incidence of complications in the observation group was lower than that in the control group (P<0.05). Conclusion In patients with sudden cerebral hemorrhage, the application of dynamic emergency care based on HFMEA concept can shorten the time required for emergency treatment, reduce the amount of cerebral hemorrhage, alleviate the degree of neurological impairment, reduce the risk of complications, and improve prognosis, which is worthy of clinical promotion.

Professor Fang Chaohui's Experience in Treating Menstrual Migraine

LV Dan-dan, WANG Si-hai, FANG Zhao-hui

2024, 42(9):  163-166. 

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Menstrual migraine belongs to the category of "headwind" and "internal injury headache" in traditional Chinese medicine. According to the principle of "treating the symptoms as soon as possible, and treating the root causes as soon as possible", it can be divided into attack period and intermittent period. "Women are based on liver and use blood". Professor Fang Chaohui believes that although there are many causes of migraine caused by menstruation, its acute attack period is most closely related to hyperactivity of liver yang and disturbance of the liver meridian, so the clinical syndrome is mainly to calm the liver and clear away heat, calm the wind and dredge the collaterals;The intermission and remission period are closely related to the menstrual qi deficiency and blood stasis, and the deficiency of liver and kidney leads to the loss of nutrition in clearing the orifices. Therefore, the clinical syndrome is mainly to soothe the liver and promote blood circulation, and regulate and replenish the liver and kidney. At the same time, with the method of ear acupoint burying beans, the meridians are harmonious and the qi and blood are smooth. Different prescriptions are given at different stages of treating migraine patients with different syndromes and migraine patients with the same meridian. With this dialectical treatment, a better clinical effect has been achieved.

Discussion on the Academic Experience of Sichuan School Famous Chinese Medicine in Treating IgA Nephropathy Based on the Theory of "Adapting to Local Conditions"

HE Jin-shi, ZHU Jia-heng, HE Yu-hua

2024, 42(9):  166-169. 

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IgA nephropathy is a clinically common primary glomerular disease, the incidence of which varies greatly between different geographic regions, different races, and ethnic groups. To date, there is no disease-specific treatment for IgA nephropathy, and the main treatment is to optimize supportive therapy. There is no name of IgA nephropathy in traditional Chinese medicine, which mostly belongs to the categories of "blood in urine" and "turbidness in urine". It is a disease characterized by deficiency and deficiency. According to its epidemiological characteristics in different races and regions, based on the theory of "adapting to local conditions" in Huangdi Neijing, combined with the unique geographical and cultural characteristics of Sichuan, the academic experience of Sichuan's famous TCM in the treatment of IgA nephropathy is summarized. Inheriting and innovating, promoting the sharing of clinical experience and the theoretical research of academic thought of famous TCM practitioners of Sichuan school.

The Risk Assessment Value of Multi-parameter Echocardiography Score for Prognosis of Heart Failure Patients

LI Na

2024, 42(9):  169-173. 

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Objective To explore and analysis the risk assessment value of multi parameter echocardiography scoring in the prognosis of heart failure patients. Methods 72 cases patients with heart failure who were hospitalized at Yanliang District Hospital of Traditional Chinese Medicine from February 2019 to May 2021 were selected as the research subjects. All patients were subjected to echocardiography examination and their multiparameter echocardiography scores were recorded. The major adverse cardiovascular events (MACE) in all patients were recorded, and correlation analysis was conducted. Results In the 72 patients, there were 22 cases(MACE group) had major cardiovascular adverse events during a 2-year follow-up, accounted for 30.6%. There were no significant differences in heart rate, gender, age, body mass index, systolic and diastolic blood pressure compared between the MACE group and the non MACE group (P>0.05). The left atrial diameter, left ventricular end diastolic diameter, and Tei index of the MACE group were significantly higher than those of the non MACE group (P<0.05), and the E/A value were significantly lower compared to the non MACE group (P<0.05). The left ventricular end diastolic volume index and left ventricular end systolic volume index in the MACE group were significantly higher than those in the non MACE group (P<0.05). There were no significant difference in the apical ejection fraction, middle ejection fraction, and basal ejection fraction between the two groups (P>0.05). In the 72 patients with heart failure, Spearman analysis showed that the incidence of MACE was related with left ventricular end diastolic volume index, left ventricular end systolic volume index, left atrial diameter, left ventricular end diastolic diameter, Tei index, E/A value after follow-up (P<0.05). Conclusion The incidence of MACE in the prognosis of heart failure patients is relatively high, and the multi-parameter score of echocardiography has great value in assessing the risk of prognosis in heart failure patients.

The Application Value of Pulmonary Ultrasound Score Combined with Serological Index Detection in Newborns with Severe Pneumonia

LIANG Yuan-bing, LIANG Zheng-xu

2024, 42(9):  173-176. 

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Objective To explore and analysis the application values of lung ultrasound scoring (LUS) combined with serological indicators detection in newborns with severe pneumonia. Methods From February 2019 to January 2023, 84 cases of neonates with severe pneumonia diagnosed and treated in Neonatal Intensive Care Unit (NICU) of a certain hospital were selected as the study subjects. All the neonates were given lung ultrasound evaluation and serum interleukin-17(IL-17) detection, and the occurrence of respiratory failure was recorded and the predictive value analysis of indices above was carried out. Results There were 24 cases diagnosed as respiratory failure(named after Respiratory failure group) in the 84 cases that accounted for 28.6%, with the others named after non Respiratory failure group. There were no significant differences in birth weight, age, length, gestational age, gender, delivery mode compared between Respiratory failure group and non Respiratory failure group (P>0.05). The lung ultrasonic scores of Respiratory failure group were significantly higher than that of non Respiratory failure group (P<0.05), and the serum IL-17 content of Respiratory failure group was significantly higher than that of non Respiratory failure group (P<0.05). In 84 children, the sensitivity of lung ultrasound score detection to predict respiratory failure of severe pneumonia newborns 78.4%, specificity of 5.4%, serum IL-17 content detection predicted the sensitivity of respiratory failure of severe pneumonia newborns 81.4%, specificity of 82.6%, combined index detection predicted the sensitivity of severe pneumonia newborns 85.7%, specificity of 82.6%. Receiver operating characteristic curve(ROC) curve analysis showed that the maximum area under the curve of pulmonary ultrasound score, serum IL-17 content and combined indices detected to predict respiratory failure in neonates with severe pneumonia were 0.782, 0.814 and 0.887, which suggested certain predictive accuracy. Conclusion The incidence of respiratory failure in neonates with severe pneumonia was relatively high, which could lead to the increase of pulmonary ultrasound score and the increase of serum IL-17 release. The application of pulmonary ultrasound score combined with serological indices in neonates with severe pneumonia could effectively predict the occurrence of respiratory failure.

Diagnostic values of transesophageal echocardiography and dual source coronary artery CT angiography in right to left shunt of patent foramen ovale

Ding Bing-qian

2024, 42(9):  177-179. 

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Objective To explore and analysis the diagnostic values of transesophageal echocardiography and dual source coronary CT angiography in right to left shunt (RLS) of patent foramen ovale (PFO). Methods From April 2020 to May 2023, 210 cases of cardiovascular disease patients diagnosed and treated at a certain hospital were selected as the research subjects. All patients were underwent transesophageal echocardiography and dual source coronary artery CT angiography, and imaging features were recorded. And all patients were undergone pathological examination and diagnostic value were calculated. Results In the 210 patients, there were 42 cases were diagnosed with right to left shunt of patent foramen ovale (PFO group), accounting for 20.0%. The left atrial diameter and pulmonary artery pressure in the PFO group were significantly higher than those in the non PFO group (P<0.05), and the left ventricular ejection fraction were significantly reduced compared to the non PFO group (P<0.05). In the 210 patients, there were 46 cases diagnosed with right to left shunt of patent foramen ovale by transesophageal echocardiography, including 28 cases of grade Ⅰ, 10 cases of grade Ⅰ, and 8 cases of grade Ⅲ. The sensitivity and specificity of transesophageal echocardiography in diagnosing right to left shunt of patent foramen ovale were 97.62% (41/42) and 97.02% (163/168), respectively. And there were 43 cases of right to left shunt of patent foramen ovale were diagnosed by dual source coronary artery CT angiography. The sensitivity and specificity of dual source coronary artery CT angiography in diagnosing right to left shunt of patent foramen ovale were 100.00% (42/42) and 99.40% (167/168), respectively. The ROC curve shows the maximum area under the curve of transesophageal CT angiography with double source coronary CT angiography of 0.875 and 0.882, and it has a certain degree of accuracy. Conclusion Compared to transesophageal echocardiography, dual source coronary artery CT angiography has a better diagnostic effect on right to left shunt of patent foramen ovale.

Early Diagnostic Value of Peripheral Blood Leukocyte Classification and Levels of PCT, CRP, and Mycoplasma Pneumoniae Antibodies in Children with Mycoplasma pneumoniae Complicated with Bacterial Infection Pneumonia

ZHAO Bi-he

2024, 42(9):  183-187. 

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Objective To explore the early diagnostic value of the classification of peripheral blood leukocytes and the levels of Calcitonin (PCT), C-reaction protein (CRP), and Mycoplasma pneumoniae antibody in children with Mycoplasma pneumoniae complicated with bacterial infectious pneumonia. Methods 500 children with Mycoplasma pneumoniae complicated with bacterial pneumonia who received treatment at the Changping District Integrated Traditional Chinese and Western Medicine Hospital in Beijing from July 2020 to March 2023 were selected as the research group, and 100 children with viral pneumonia who received treatment at the same time at the Changping District Integrated Traditional Chinese and Western Medicine Hospital in Beijing were selected as the case control group. 100 healthy children who underwent physical examination at the same time were selected as the control group, and their blood samples were tested for PCT, CRP, and The levels of Mycoplasma pneumoniae antibody IgM and peripheral blood leukocyte classification indicators (white blood cell count, neutrophil percentage, lymphocyte percentage, monocyte percentage) were compared between the two groups of children. The diagnostic value of the above indicators for Mycoplasma pneumoniae combined with bacterial infection pneumonia was calculated by drawing receiver operating characteristics (ROC) of the subjects, And calculate the area under curve (AUC). Results The blood PCR, CRP, and IgM levels of Mycoplasma pneumoniae antibodies in the study group were significantly higher than those in the case control group and control group children (P<0.05).The peripheral blood white blood cell count, neutrophil percentage, and monocyte percentage of children in the study group were significantly higher than those in the case control group and control group, while the lymphocyte percentage was significantly lower than those in the control group (P<0.05). By plotting ROC curves and calculating, it was found that the diagnostic AUCs for PCT, CRP, and IgM antibodies against Mycoplasma pneumoniae combined with bacterial pneumonia were 0.934 (95%CI=0.900-0.968, P<0.001), 0.928 (95%CI=0.880-0.975, P<0.001), and 0.780 (95%CI=0.712-0.848, P<0.001). The diagnostic AUCs of white blood cell count, neutrophil percentage, lymphocyte percentage, and monocyte percentage in peripheral blood white blood cell classification for Mycoplasma pneumoniae complicated with bacterial infection pneumonia were 0.957 (95%CI=0.925-0.988, P<0.001), 0.768 (95%CI=0.700-0.836, P<0.001), 0.670 (95% CI=0.595-0.746, P<0.001), and 0.765 (95%CI=0.698-0.832, P<0.001). Conclusion The blood PCT, CRP, and IgM of Mycoplasma pneumoniae antibodies in children with Mycoplasma pneumoniae combined with bacterial infection pneumonia significantly increased compared to healthy children, and the level of white blood cell classification also showed significant changes. The above indicators have good application value in the early diagnosis of Mycoplasma pneumoniae combined with bacterial infection pneumonia in children.