The Clinical Efficiency of Jindan Paishi Decoction in Treating Patients with Damp-Heat Type of Ureteral Calculus

Abstract

Abstract: Objective This study aims to explore the clinical efficiency of Jindan Paishi (JDPS) decoction in treating patients with damp-heat type of ureteral calculus. Methods Total of 62 patients of ureteral calculus with damp -heat syndrome were hospitalized in Peoples' Hospital of Pingyi County from Jan 2021 to Dec 2022. According to randomized digital table method, all patients were randomly divided into treatment group (n=31) orally treated with JDPS decoction and control group (n=31) orally given Shenshitong granules for 30 days continuously. The pain degrees of patients were evaluated according to WHO Pain Grade. The traditional Chinese medicine (TCM) syndromes, micturition frequency and urine volume were recorded. The number of WBC and RBC in urine, the WBC classification and numbers in blood, creatinine and urea nitrogen were determined by biochemical assay. The size and number of ureteral calculus were detected by imaging examination, and at last the total effective rate of the two drugs was evaluated comprehensively. Results After treatment, all the pain degree and pain time, the tongue coating color and pulse conditions, the size and number of ureteral calculus, the urine volume and times of patients were significantly improve than those before treatment respectively; the size and number of ureteral calculus were significantly reduced than those before treatment; the numbers of WBC and RBC in urine were significantly decreased than those before treatment; the creatinine (Cr) and urea nitrogen (BUN) levels in serum were significantly decreased than those before treatment; the numbers of blood WBC was significantly reduced while the neutrophils and lymphocytes increased than those before treatment(P<0.05). The pain degree and time of patients in treatment group were significantly decreased than those in control group(P<0.05); the number of WBC in urine,the number of RBC,the serum levels of Cr and BUN, and the number of WBC in blood in treatment group were significantly lower than those in control group(P<0.05). The total effective rate of patients in treatment group (90.32%) was significantly higher than that in control group (80.64%)(P<0.05). Conclusion sJDPS decoction might improve clinical symptoms and renal function of patients with damp-heat type of ureteral calculus, and enhance the anti-inflammatory effect of blood WBC.

Key words: Jindan Paishi decoction, ureteral calculus, damp-heat syndrome, clinical effect

CLC Number:

R277.5

SUN Tao, CAI Ke, LIU Zi-shan, ZOU Chun-li, SIN Long-jun. The Clinical Efficiency of Jindan Paishi Decoction in Treating Patients with Damp-Heat Type of Ureteral Calculus[J]. ZHONGHUA YANGSHENG BAOJIAN, 2024, 42(9): 12-16.

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