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Table of Content

    16 May 2023, Volume 41 Issue 10
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    Evaluation of Treatment by Reverse Iontophoresis in a Rabbit Hyphema Model Introduction
    SUN Shou-bin, YANG Jie
    2023, 41(10):  1-4. 
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    Objective The purpose of this study was to treat hyphema by using reverse ion introductio to extract iron from anterior chamber of the rabbit cornea. Methods 24 rabbits were randomly divided into three groups, with 8 rabbits in each group. The 8 rabbits in group I were not modeled as the blank control group; The anterior chamber blood model was fabricated in the right eyes of 16 rabbits, and after modeling, they were randomly divided into two groups Ⅱ and Ⅲ with 8 eyes in each group. The group Ⅱ was called model control group, which was given 0 ma current intensity reverse iontophoresis treatment to observe the natural changes of anterior chamber blood volume; The group Ⅲ was treated by transcorneal reverse iontophoresis technique at a current intensity of 0.4 Ma once daily for 15 min for seven days. The absorption velocity of the anterior chamber blood was observed by slit lamp microscopy, the concentration of iron ions in the aqueous humor of each group was measured by inductively coupled plasma optical emission spectrometer, and the pathological changes of the cornea were observed by histological examination. Results The iron concentration in aqueous humor was greatly increased in the modeling group compared with control group, but it was greatly reduced by reverse iontophoresis treatment. Histological examination indicated that inflammatory cell infiltration and iron deposition in the RI treatment group were significantly less than the modeling group. Conclusions Reverse iontophoresis in cornea is a non-invasive and promising approach to extract iron from the anterior chamber to treat hyphema.
    Application Exploration of PBL Teaching Method Based on MDT Diagnosis and Treatment Model in Clinical Teaching of Endocrinology Department of Chinese Medicine
    FANG Zhao-hui, WANG Si-hai, ZHAO Jin-dong, BAO Tao-tao, NI Ying-qun, NIU Yun-fei, LIU Jian, WU Ji-ping, SHI Guo-bin, LU Ruimin
    2023, 41(10):  4-7. 
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    With the continuous progress of medical education reform, PBL teaching method and MDT diagnosis and treatment model are increasingly favored by clinical teachers and medical students. They each have corresponding advantages.PBL teaching method based on MDT diagnosis and treatment model (MDT-PBL teaching method) is a perfect combination of the two. It can effectively avoid their own disadvantages, highlight the huge advantages and prospects, and it not only can improve the clinical thinking ability of integrated traditional Chinese and Western medicine of intern students, resident doctor standardized training students,graduate students, visiting students, but also can cultivate their ability to solve clinical practical problems, which is conducive to the training of independent clinical outstanding physicians of integrated traditional Chinese and Western medicine. It provides practical reference for medical students to improve their comprehensive knowledge and diagnosis and treatment level.
    Design and Implementation of Internet+ Rehabilitation Nursing Platform for Stroke Patients with Dysphagia Based on Multiple Disciplinary Team(MDT)
    MA Ling, ZHANG Qi, YE Jiao, WANG Jun-ling, SI Wei-jia
    2023, 41(10):  8-11. 
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    Objective To design and construct an “Internet+MDT” rehabilitation care platform for stroke dysphagia, and to explore the application effect of the platform. Methods According to the nursing needs of stroke patients with dysphagia at home and the current situation of “Internet+nursing services”, a multidisciplinary collaborative home nursing platform for stroke patients with dysphagia was designed based on the J2EE layered idea; From July 2020 to June 2021, 80 stroke patients with dysphagia were randomly selected from China Resources WISCO general hospital and applied the platform. Results After using this platform to receive home rehabilitation care, the Wada drinking water test rating and the stroke specific quality of life score of patients in the intervention group were better than those in the control group (P<0.05). Conclusion The home care platform of stroke swallowing disorder based on “Internet+ MDT” can give full play to the advantages of Internet technology, significantly improve the swallowing rehabilitation effect of patients, and improve their quality of life after stroke.
    Clinical Significance of Detection of Lymphocyte Subsets in Patients with Pulmonary Infection after Kidney Transplantation
    ZHOU Ming-zhen, SUN Xu-yong
    2023, 41(10):  12-15. 
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    Objective To explore and analysis the clinical significance of detection of lymphocyte subsets in patients with pulmonary infection after kidney transplantation. Methods From January 2020 to May 2022, 50 cases of postoperative patients who completed kidney transplantation in the Transplantation Center of the Second Affiliated Hospital of Guangxi Medical University were selected as the research subjects, and the content of lymphocyte subsets was detected. All patients were given immunosuppressive therapy after operation, and the incidence of pulmonary infection was followed up and correlation analysis was performed. Results Among the 50 patients, 12 cases (infection group) developed infection 6 months after surgery, accounting for 24.0%; Four pathogens infected were found(Klebsiella pneumoniae in 4 cases, Pseudomonas aeruginosa in 4 cases, Acinetobacter baumannii in 2 cases, Escherichia coli in 1 case and Candida albus in 1 case). The relative contents and absolute content of CD3+ and CD4+ lymphocyte subsets in the infection group were significantly lower than those in the non-infection group(P<0.05), and the relative contents and absolute content of CD8+ lymphocyte subsets were significantly higher than those in the non-infection group(P<0.05). Pearson analysis showed that the relative contents of CD3+, CD4+, CD8+ lymphocyte subsets and absolute content were correlated with the occurrence of pulmonary infection(P<0.05). Binary logistic regression analysis showed that the relative content and absolute content of CD3+, CD4+, CD8+ lymphocyte subsets were the important factors that affected the occurrence of pulmonary infection(P<0.05). Conclusion Pulmonary infection is common after kidney transplantation. The relative content of CD3+, CD4+, and CD8+ lymphocyte subsets are correlated with the occurrence of pulmonary infection. The detection of lymphocyte subsets can effectively predict the occurrence of pulmonary infection in patients.
    The Application Values of Multiple Acoustic Signs of Musculoskeletal Ultrasound in the Diagnosis of Primary Frozen Shoulder
    WANG Wei
    2023, 41(10):  15-19. 
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    Objective To explore the application values of multiple acoustic signs of musculoskeletal ultrasound in the diagnosis of primary frozen shoulder, to provide a reference for promoting the application of musculoskeletal ultrasound. Methods From February 2019 to July 2022, 110 patients with primary frozen shoulder who were diagnosed and treated in Qingyang Traditional Chinese Medicine Hospital of Gansu Province were selected as the frozen shoulder group, and 110 healthy people who participated in physical examination From February 2019 to July 2022 in Qingyang Traditional Chinese Medicine Hospital of Gansu Province were selected during the same period. as a healthy control group. All patients were underwent musculoskeletal ultrasonography, and acoustic signs were recorded. At the same time, patients were given arthroscopy, and were to determine the diagnostic value. Results The acoustic signs such as hydrocele, hypoechoic rotator cuff space, and joint capsule thickening in the frozen shoulder group which were significantly higher than those in the healthy control group (P<0.05). The thickness of supraspinatus tendon, infraspinatus tendon and myofascia in frozen shoulder group were significantly higher than those in healthy control group (P<0.05). The musculoskeletal ultrasound semi-quantitative score in the frozen shoulder group was significantly higher than that in the healthy control group (P<0.05). Among the 220 patients in the frozen shoulder group and the healthy control group, 114 cases were diagnosed as frozen shoulder by musculoskeletal ultrasound, and the sensitivity and specificity of multiple acoustic signs of musculoskeletal ultrasound in the diagnosis of primary frozen shoulder were 99.09% (109/110) and 95.45% (105/110), the Kappa value is 0.945. Conclusion Primary frozen shoulder is often accompanied by musculoskeletal ultrasound tendon hydrocele, hypoechoic rotator cuff space, joint capsule thickening and other acoustic signs, as well as abnormal synovial blood flow characteristics. Musculoskeletal ultrasonography has high sensitivity and specificity for the diagnosis of primary frozen shoulder.
    Effect of Acupoint Scraping Combined with Traditional Chinese Medicine Hot Package on Defecation Function of Patients with Gastrointestinal Dysfunction after General Surgery
    LI Chuan-jiang
    2023, 41(10):  19-22. 
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    Objective To investigate the application effect of acupoint gua sha combined with traditional Chinese medicine hot bao in patients with gastrointestinal dysfunction after laparoscopic surgery in general surgery. Methods A retrospective analysis was performed on the medical records of 84 patients with gastrointestinal dysfunction after laparoscopic general surgery admitted to Pingyi County Hospital of Traditional Chinese Medicine from March 2020 to March 2022, and divided into two groups according to different treatment methods. Among them, 40 patients who underwent conventional Western medicine treatment were included in the control group, while 44 patients who underwent acupoint gua sha combined with traditional Chinese medicine hot bambao were included in the observation group, all of whom were treated for 2 weeks and observed 1 month after treatment. The clinical efficacy, symptom improvement, recovery and quality of life of the two groups were compared. Results The total effective rate of treatment in the observation group was higher than that in the control group, and the recovery time of bowel sounds, exhaust time, defecation time and activity time were shorter than those in the control group, with statistically significant differences (P<0.05). Before treatment, there were no significant differences (P>0.05) between the two groups compared with the scores of each dimension in the health survey brief table (SF-36); After treatment, the scores of constipation, poor appetite, nausea and vomiting and abdominal distension in the observation group were lower than those in the control group, and the scores of all dimensions in SF-36 were higher than those in the control group,with a statistically significant difference (P<0.05). Conclusion Acupoint gua sha+traditional Chinese medicine hot bag in the treatment of patients with gastrointestinal dysfunction after laparoscopic general surgery has obvious effects,which can significantly alleviate its clinical manifestations, accelerate the improvement of bowel function,and then effectively improve the quality of life, which is worthy of vigorous clinical promotion.
    Effect of Danqitongluo Capsule Combined with Dipyridamole on Angina Pectoris of Coronary Heart Disease
    HE Miao-miao, WANG Chang
    2023, 41(10):  22-25. 
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    Objective To investigate the effect of Danqitongluo capsule combined with dipyridamole on angina pectoris of coronary heart disease. Methods A total of 110 patients with coronary heart disease and angina pectoris admitted to Neijiang Hospital of Traditional Chinese Medicine from January 2021 to September 2022 were selected, and was divided into two groups according to the randomized number table method. The control group was treated with dipyridamole, and the observation group was treated with Danqitongluo capsule and dipyridamole. The levels of serum lipoprotein associated phospholipase A2 (Lp-PLA2), soluble intercellular adhesion molecule-1 (sICAM-1), hypersensitive C-reactive protein (hs-CRP) and monocyte chemoattractant protein-1 (MCP-1) were measured in the two groups, and the whole blood viscosity (WBV), platelet adhesion rate (PAR), fibrinogen (FIB), plasma viscosity (PV) and TCM symptoms were compared between the two groups. Results The response rate in the observed group was 96.36%, which was significantly higher than the 74.54% in the control group (P<0.05). After 1 month of treatment, the serum Lp-PLA2, sICAM-1, hs-CRP and MCP-1 levels in the two groups were significantly reduced (P<0.05), and the serum Lp-PLA2, sICAM-1, hs-CRP and MCP-1 levels in the observation group were significantly lower than those in the control group (P<0.05). After 1 month of treatment, WBV, PV, FIB and PAR in the two groups were significantly reduced (P<0.05), and WBV, PV, FIB and PAR in the observation group were significantly lower than those in the control group (P<0.05). After 1 month of treatment, the scores of fatigue, chest pain, shortness of breath, palpitation and chest distress in the two groups were significantly reduced (P<0.05), and the scores of fatigue, chest pain, shortness of breath, palpitation and chest distress in the observation group were significantly lower than those in the control group (P<0.05). Conclusion Dipyridamole combined with Danqitongluo capsule can significantly improve the hemorheology of patients with coronary heart disease and angina pectoris, reduce inflammatory reaction and TCM symptoms, and improve the efficacy.
    Clinical Analysis of Routine Treatment Combined with Oral Chinese Herbal Decoction in the Treatment of Coronary Heart Disease with Angina Pectoris
    WANG Yu
    2023, 41(10):  29-31. 
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    Objective To observe the clinical effect of routine treatment combined with oral Chinese herbal decoction in the treatment of coronary heart disease with angina pectoris. Methods From January 2020 to January 2021, 100 patients with coronary heart disease and angina pectoris were selected and treated in Luzhong Hospital of Peking University Medical College. They were randomly divided into control group and observation group with 50 patients in each group. The control group was treated with oral aspirin and atorvastatin, while the observation group was treated with Xuefu Zhuyu Decoction on the basis of the control group. The treatment period was 15 days. The clinical treatment efficiency, angina relief time, attack times, hospital stay, and treatment satisfaction between the two groups were observed and compared. Results The treatment response rate of patients in the observation group was significantly better than that of the control group, the difference between the two groups was significant differenc (P<0.05). Patients in the observation group had a shorter angina relief time and hospital stay than those in the control group, and all data were significantly different (P<0.05). The treatment satisfaction of patients in the observation group was significantly higher than that of the control group (P<0.05). Conclusion For patients with coronary heart disease and angina pectoris, the treatment of oral aspirin and atorvastatin combined with Xuefu Zhuyu Decoction has obvious effects, it can effectively relieve the clinical symptoms of patients, shorten the duration of angina pectoris, reduce the number of attacks, shorten the length of hospital stay, promote the harmonious coexistence of nurses and patients, and improve the efficiency of treatment.
    Dose Dependence of Valsartan Dose on Ventricular Vascular Coupling Index in Patients with Heart Failure
    GUO Xue-feng
    2023, 41(10):  51-54. 
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    Objective To investigate the effect of different doses of valsartan on ventricular vascular coupling index in patients with heart failure. Methods 400 patients with heart failure who were treated in our hospital from January 2020 to August 2022 were selected as the research objects. They were divided into the observation group (n=200, receiving 40 mg/d valsartan) and the control group (n=200, receiving 80 mg/d valsartan) according to the random number table method. The difference of the treatment effect between the two groups was compared, and the difference of the cardiac function index, myocardial injury index and adverse reaction rate index between the two groups before and after treatment was compared. Results The number of patients in the observation group was 80, and the number of patients in the observation group was 104. The total effective rate of the observation group slightly lower than that of the control group, but the difference was not significant(P>0.05); After treatment, LVEF and LVEDD of the two groups were significantly higher and lower than before treatment(P<0.05), but there was no significant difference between the two groups after treatment(P>0.05); After treatment, the levels of H-FABP and NT proBNP in the two groups were significantly lower than those before treatment(P<0.05). After treatment, the levels of NT proBNP in the control group were lower than those in the observation group(P<0.05); The total incidence of adverse reactions in the observation group was significantly lower than in the control group (P<0.05). Conclusion Valsartan is effective in improving the clinical symptoms of patients with heart failure. It can improve the heart function and alleviate the inflammatory state of patients. It is suggested that the dosage should be set at 40 mg/d. Increasing the dosage will not significantly improve the therapeutic effect, but will significantly increase the adverse reactions rate.
    Research Progress of the Tibetan Medicine “Zuotai”
    DENG Cheng-qi, Luobu Luosong, YIN Yi-qing, ZHENG Xiang-qian
    2023, 41(10):  64-67. 
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    Tibetan medicine is an important traditional medicine in China. "Zuotai" is the most representative concoction in Tibetan medicine, which is one of the main raw materials used to formulate many kinds of precious Tibetan medicine preparations and plays a significant role in the Tibetan medicine system. Because of its complex composition and the presence of many heavy metals, the application and promotion of "Zuotai" in modern medical clinics are somewhat restricted. In this paper, we review the chemical composition, mechanism of action, safety and application of "Zuotai" in recent years, with the aim of providing reference for further research on “Zuotai”.
    Current Status of Symptom Group and Symptom Management Strategy in Esophageal Cancer Patients
    REN Xiu-qin
    2023, 41(10):  82-84. 
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    Esophageal cancer is characterized by high malignancy degree, complicated disease, many accompanying symptoms and high recurrence rate, so it is especially important for patients to self-evaluate, timely detection and self-management of their own symptoms. In order to explore the symptom cluster and symptom management strategies of esophageal cancer patients during treatment, increase the depth and breadth of the understanding of self-management status, this article will review the qualitative and quantitative research to provide the basis for the designation of later management strategies.