Table of Content

01 March 2025, Volume 43 Issue 5

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Prospective Research on Mechanical Thrombectomy for Blood Pressure Management in Acute Ischemic Stroke: A Scoping Review

CHEN Yu-xiang, WANG Min, WANG Sha-sha, WANG Zong-yu, SONG Nan-nan, YANG Hai-yan

2025, 43(5):  1-4. 

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Objective To review the prospective intervention research on mechanical thrombectomy for blood pressure management in AIS. Methods A total of 10 Chinese and English databases were searched from the establishment of the database to April 1, 2024. Results A total of 13 studies were included, of which 7 were completed studies and 6 were ongoing studies. There were 12 randomized controlled trials and 1 cohort study. The intervention protocols consisted of 7 intensive blood pressure lowering regimens, 4 personalized blood pressure management strategies, and 2 blood pressure raising regimens. Conclusion Relevant researchers should develop personalized blood pressure management strategies based on blood pressure and prognostic factors, and further verify and promote them.

Exploration and Practice of Ideological and Political Education in the Course of "Fundamentals of Traditional Chinese Nursing" for Nursing Undergraduates in Traditional Chinese Medicine Universities

ZHANG Qiong, YANG Xue, WAN He-jia, WANG Yun-lu, QIN Yuan-mei

2025, 43(5):  5-8. 

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Based on the understanding of the educational concept of Ideological and Political Education in Curriculum, explores the teaching methods of ideological and political education in the course of Basic Nursing of Chinese Medicine in Chinese Medicine universities. It analyzes the necessity of implementing ideological and political education in the course; by deeply mining the ideological and political elements of the course, it constructs the ideological and political system of Basic Nursing of Chinese Medicine; it deepens the teaching reform, explores the ideological and political education methods of cultivating people in Basic Nursing of Chinese Medicine; it builds a high-quality ideological and political education team for Basic Nursing of Chinese Medicine, so as to effectively link and integrate classroom teaching and ideological and political education teaching, effectively cultivating students' confidence in Chinese medicine culture, professional emotions in Chinese Medicine nursing, social responsibility, scientific spirit and other qualities, and effectively achieving the fundamental task of "cultivate virtues and morality" in course teaching.

The Effect of the Ideological and Political Teaching of the Department of Rheumatology and Immunology Based on the Concept of OBE Applied to the Trainees

FU Rong, YAN Qi, WANG Jing-ya, WANG Li-li, ZHU Cheng-cheng, KUAI Ying-shu, WANG Ning, LI Chun-xiang, LIU Li-juan, CHU Rui

2025, 43(5):  8-13. 

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Objective To analyze the impact of teaching rheumatology and immunology trainee civics based on the concept of Outcome-Based Education (OBE) on the learning effect of trainees. Methods Thirty rheumatology and immunology trainees from January 2022 to December 2022 were selected as the control group by retrospective analysis, and conventional teaching was implemented, while 31 rheumatology and immunology trainees from January 2023 to December 2023 were set as the experimental group, and Civics teaching based on the concept of OBE was carried out, and the theoretical knowledge, practical skills, and learning effects of OBE on the trainees in the two groups were analyzed. groups' theoretical knowledge, practical skills, and satisfaction, and assessed the trainees' thinking ability using the Critical Thinking Disability Inventory (CTDI-CV). Results The scores of theoretical knowledge and practical operation skills in OBE group were higher than those in traditional group, and the differences were statistically significant (P<0.05). Before teaching, there was no significant difference in CTDI-CV scores between the two groups (P>0.05). After teaching, CTDI-CV scores in both groups were higher than before teaching, and OBE group was higher than traditional group, the difference was statistically significant (P<0.05). The scores of teaching content, teaching method, teaching attitude, teaching effect and ideological education integration in OBE group were higher than traditional group, and the differences were statistically significant (P<0.05). Conclusion The OBE concept of civic teaching can be of high value in improving the theoretical knowledge and practical skills of rheumatology and immunology traineeship, which can not only achieve good critical thinking skills, but also effectively improve the satisfaction of teaching.

A Report on Multi-time and Multi-mode Analgesia Plan in the Perioperative Period for An Elderly Patient with Femoral Neck Fracture

SUN Hai-bin, LIU Yu-yin, LIU Li-na, LIU Ji-chang, LIANG Kai, SUN Yong-gang

2025, 43(5):  13-16. 

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Hip fractures in the elderly are often referred to as “the last fracture of life” and with the aging of the population, the incidence of hip fractures has become a serious social problem. Studies have shown that hip fractures affect 18% of women and 6% of men worldwide, with 30% of cases originating from China. This report presents a case of an elderly femoral neck fracture patient treated in the Department of Sports Medicine at Weifang Traditional Chinese Medicine Hospital in July 2023, highlighting the perioperative multi-timing, multi-modal analgesic anesthesia plan. The patient was an elderly female, 76 years old, who was admitted to the hospital with a fall injury resulting in swelling and pain in the left hip and limitation of activities for 10 days. After a clear diagnosis at a local hospital, she received conservative treatment for 10 days. During this period, she suffered from unbearable pain and severe restrictions on sleep and food intake, and the treatment outcome was unsatisfactory, so she was admitted to Weifang Traditional Chinese Medicine Hospital for further treatment. Through the perioperative multi-timing, multi-modal anesthesia intervention for this patient, we achieved the goal of comfortable perioperative care. The patient recovered and was discharged from the hospital, with a high degree of satisfaction from the patient and his family.

Clinical Effect of Moxibustion at Baihui and Yongquan Acupoints on Patients with Primary Insomnia with Cardio-Renal Incompatibility

ZHANG Lei, ZHANG Zheng, XU Hai-yan, HUANG Guo-min

2025, 43(5):  17-20. 

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Objective To compare with conventional western medicine, to observe the clinical efficacy advantages of moxibustion at Baihui and Yongquan points in the treatment of primary insomnia of heart-kidney disharmony type. Methods A randomized RCT design was adopted, and 60 qualified subjects were included. Divide into two groups using random number table method. Experimental group (n=30): Acupuncture treatment based on moxibustion Baihui and Yongquan, once a day for 2 weeks; Control group (n=30): Oral estazolam tablets, 1 mg/time, once a day , take the medicine half an hour before going to bed for 2 weeks. Observed indicators were Pittsburgh Sleep Quality Index (PSQI), Self-Rating Depression Scale (SDS) ,Traditional Chinese Medicine Syndrome Score,clinical efficacy. Results After 2 consecutive weeks of treatment, the total PSQI score of the test group was significantly lower than the total score of the control group, and the difference was statistically significant (P<0.05). The total SDS score of the experimental group was significantly lower than the total score of the control group, and the difference was statistically significant (P<0.05). The TCM syndrome score of the experimental group was significantly lower than the total score of the control group, and the difference was statistically significant (P<0.05). Comparing the clinical efficacy, the total effective rate of the test group was 93.33%, and the total effective rate of the control group was 86.67%. The difference was statistically significant (P<0.05). Conclusion Moxibustion at Baihui and Yongquan points has significant clinical efficacy in treating primary insomnia of heart-kidney disharmony type.

Clinical Study of Bushen Tongli Decoction Combined with Eswl in the Treatment of Damp-Heat Accumulation Syndrome of Upper Urinary Tract Calculi

CHEN Nian-ben, WU Jing-xing, HU Qing-lin

2025, 43(5):  20-24. 

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Objective To explore the clinical efficacy of Bushen Tongli decoction combined with extracorporeal shock wave lithotripsy (ESWL) in the treatment of damp-heat accumulation syndrome of upper urinary tract calculi. Methods This study included 100 patients with upper urinary tract calculi who were treated with ESWL in Chuzhou Integrated Hospital of Anhui University of traditional Chinese Medicine in 2023. They were randomly divided into treatment group (n=50) and control group (n=50). Both groups received routine postoperative treatment, and the treatment group was treated with Bushen Tongli decoction on the basis of routine treatment until 14 days after operation, and the therapeutic effects of the two groups were compared. Results After treatment, the symptoms scores of urine pain, abnormal urination, low back pain and frequent urination in the treatment group were significantly lower than those in the control group(P<0.05). The observation group was superior to the control group in the overall effective rate(P<0.05). The adverse reactions in the treatment group was significantly lower than that in the control group(P<0.05). The levels of serum creatinine, blood urea nitrogen and C-reactive protein were decreased in both groups, and the above indexes in the treatment group were lower than those in the control group(P<0.05). Conclusion Bushen Tongli decoction combined with ESWL in the treatment of upper urinary tract calculi patients, not only improve the clinical symptoms, and improve the cure rate, showing an excellent treatment effect, is a clinical treatment method worth popularizing.

Clinical Efficacy of Modified Sanbi Decoction Combined with Methotrexate in the Treatment of Liver-Kidney Deficiency Type Rheumatoid Arthritis: A Randomized Controlled Trial

YANG Wan-qing, ZHANG Chun-fang, SHI Jian, QIN Jia-chao, ZHANG Chen-long, WANG Yu-jie, GUO Kai-hang, LI Peng-fei

2025, 43(5):  34-38. 

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Objective To observe the clinical efficacy of modified Sanbi decoction combined with methotrexate in the treatment of rheumatoid arthritis (RA). Methods A total of 63 patients with RA admitted between September 2021 and September 2023 were selected as the study subjects. They were randomly divided into two groups: the control group (n=31) received oral methotrexate tablets, and the treatment group (n=32) received modified Sanbi decoction in addition to oral methotrexate tablets. Both groups were treated for 4 weeks. Compare the levels of morning stiffness, joint pain, swelling, and grip strength before and after treatment between the two groups. Detect the erythrocyte sedimentation rate (ESR), rheumatoid factor (RF), and C-reactive protein (CRP) levels. Additionally, compare the safety indicators such as T lymphocyte helper factor (OKT4), T lymphocyte suppressor factor (OKT8), and OKT4/OKT8 ratios to assess the disease activity before and after treatment in both groups. Results Compared with before treatment, both groups showed a significant reduction in morning stiffness duration, joint pain and swelling scores (P<0.05), and an increase in grip strength (P<0.05) after treatment. ESR, RF, and CRP levels were significantly decreased (P<0.05), while OKT4 levels , OKT8 levels increased, and OKT4/OKT8 ratio decreased significantly (P<0.05). Compared with the control group, the treatment group showed improvements in morning stiffness duration, joint pain, joint swelling, and grip strength levels (P<0.05). The levels of ESR, RF, and CRP were all lower (P<0.05). Additionally, the levels of OKT4 and OKT8 were higher, and the OKT4/OKT8 ratio was lower (P<0.05). Conclusion Modified Sanbi decoction combined with methotrexate is effective in treating RA, improving clinical symptoms, reducing inflammation, inhibiting disease activity, and preventing bone destruction.

Comparison of Clinical Efficacy between Bronchial Artery Chemoembolization and Systemic Intravenous Chemotherapy in the Treatment of Mid to Late Stage Non-Small Cell Lung Cancer

ZHANG Zhi-hui

2025, 43(5):  51-55. 

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Objective To compare the clinical efficacy of bronchial artery chemoembolization (BACE) and systemic intravenous chemotherapy in patients with mid to late stage non-small cell lung cancer (NSCLC). Methods A total of 64 patients with mid to late stage NSCLC from October 2017 to January 2023 who were admitted in Lingcheng District Traditional Chinese Medicine Hospital in Dezhou city were selected. By random number table method, they were divided into the observation group (32 cases, BACE) and the control group (32 cases, systemic intravenous chemotherapy). The clinical efficacy, serum tumor markers, inflammatory factors, quality of life, safety, cost-effectiveness, and one-year survival rate in both groups were compared. Results In the Objective response rate (ORR) and disease control rate (DCR), in comparison of the control group, the observation group were higher (P<0.05). After treatment, the carbohydrate antigen 125 (CA125), carcinoembryonic antigen (CEA), and carbohydrate antigen 19-9 (CA19-9) levels in both groups were decreased (P<0.05), and in comparison of the control group, the observation group was lower (P<0.05). After treatment, the tumor necrosis factors- α (TNF- α), C-reactive protein (CRP) and interleukin-8 (IL-8) levels were decreased in both groups (P<0.05), and in comparison of the control group, the observation group was lower (P<0.05). After treatment, the Karnofsky functional status score (KPS) in both groups were increased (P<0.05), and in comparison of the control group, the observation group was higher (P<0.05). In the incidence of adverse reactions (bone marrow suppression, gastrointestinal reactions, anemia), in comparison of the control group, the observation group was lower (P<0.05). There were no serious complications such as pulmonary embolism in the observation group, and one case experienced bleeding. After internal medicine treatment, the bleeding stopped. In the one-year survival rate, in comparison of the control group 62.50% (20/32), the observation group 88.00% (22/25) was higher (P<0.05). The cost-effectiveness ratio of the observation group was better than that of the control group. Conclusion For patients with mid to late stage NSCLC, compared with systemic intravenous chemotherapy, BACE treatment can improve clinical efficacy, regulate serum tumor markers and inflammatory factor levels, improve quality of life, improve 1-year survival rate, and with high safety, achieve better cost-effectiveness.

Application of High-Resolution CT Combined with Texture Analysis in the Diagnosis of Lung Cancer

XU Yun-long

2025, 43(5):  55-59. 

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Objective To explore the clinical value of high-resolution computed tomography (Computed Tomography, CT) combined with texture analysis in the diagnosis of lung cancer. Methods A prospective study was conducted on 100 suspected lung cancer patients who visited hospitals from Chifeng City Cancer Hospital in January 2021 to December 2023. All patients underwent high-resolution CT combined with texture analysis and histopathological biopsy. The histopathological biopsy results were used as the gold standard to compare the diagnostic value of high-resolution CT alone and in combination with texture analysis for lung cancer. Results 63 out of 100 highly suspected lung cancer patients were confirmed to have lung cancer through histopathological examination, accounting for 63.00% (63/100). Histopathological examination was used as the gold standard, the detection rate of lung cancer using high-resolution CT was 74.60% (47/63), and the detection rate of lung cancer using high-resolution CT combined with texture analysis was 92.06% (58/63). The sensitivity, accuracy, and negative predictive value of high-resolution CT combined with texture segmentation in diagnosing lung cancer were higher than those of high-resolution CT alone, with statistical significant differences (P<0.05). The consistency between the combined examination and the gold standard for diagnosing lung cancer was the highest, with a Kappa value of 0.785. Conclusion The accuracy of high-resolution CT combined with texture analysis for lung cancer is higher than that of high-resolution CT alone, and it has better consistency with the gold standard, making it more valuable for application.

Analysis of the Clinical Diagnostic Value of Breast Molybdenum Target X-ray Photography Combined with CA15-3, CA125, CEA, and CYFRA21-1 in Breast Cancer

WANG Xin

2025, 43(5):  62-66. 

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Objective To analyze the clinical diagnostic value of X-ray combined with glycoantigen 15-3 (CA15-3), sugar antigen 125 (CA125), carcinoembryonic antigen (CEA), and cytokeratin 19 fragment antigen 21-1 (CYFRA21-1) in breast cancer (BC). Methods A total of 78 BC patients admitted to our hospital from May 2023 to January 2024 were selected as the study group, and another 80 patients with benign breast lesions were selected as the control group. Baseline data of both groups were recorded, the levels of tumor markers (CA15-3, CA125, CEA, CYFRA21-1) were determined by chemiluminescence, the working characteristics (ROC) curve was drawn, and the area under the curve (AUC) was used to analyze the diagnostic value of tumor markers and mammo X-ray photography alone and in combination. Results The serum CA15-3, CA125, CEA and CYFRA21-1 in the study group were higher than the control group, statistically different (P<0.05); ROC curve analysis showed that the AUC of tumor marker and mammo X-ray was 0.903, sensitivity of 86.36%, specificity of 84.21%, and higher predictive value than the single index, and the difference was statistically significant (P<0.05). Conclusion The level of CA15-3, CA125, CEA, CYFRA21-1 and mammography X-ray photography all have good predictive value for BC, and the combined prediction efficiency of both is better.

Study on the Molecular Mechanism of Pleurotus Ostreatus-Zedoary Combination in the Treatment of Pancreatic Cancer Based on Network Pharmacology

HUA Wen, YANG Shi-yu, CHEN Mu-wen, WANG Yi-yi, CHEN Jun

2025, 43(5):  92-96. 

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Objective To explore the molecular mechanism of pleurotus ostreatus-zedoary turmeric combination in the treatment of pancreatic cancer by means of network pharmacology. Methods The main active components and action targets of pleurotus ostreatus-zedoary were obtained by TCMSP database, the pancreatic cancer related targets were obtained by OMIM, TTD, GeneCards and other databases, the intersection targets of traditional Chinese medicine and disease were obtained, and the protein interaction network (PPI) was analyzed by String database, and the core targets were screened. Finally, the ClueGO plug-in of Cytoscape3.7.2 software is used to analyze the enrichment of intersection targets by GO and KEGG, and a visual network of active components-target-signal pathway of traditional Chinese medicine is constructed. Results Six active components of pleurotus ostreatus-zedoary in the treatment of pancreatic cancer were obtained and 10 core targets,enrichment analysis mainly involved in biological processes and 4 mainly regulated signaling pathways in cancer. Conclusion The research based on network pharmacology shows that pleurotus ostreatus-zedoary can play a role in the treatment of pancreatic cancer through active components such as β-sitosterol and regulating PI3K-Akt signaling pathway, indicating that traditional Chinese medicine has the characteristics of multi-components, multi-targets and multi-pathways, and has a certain value in clinical application.

Discussing the Treatment of Chronic Heart Failure with Pogejiuxin Decoction Based on Circular Motion Theory

GUO Ning-hua, WANG Zhi-chao

2025, 43(5):  96-99. 

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Circular motion is an important doctrine of Chinese medicine. The Pogejiuxin Decoction is an empirical formula created by Dr.Li Ke. In the rural areas where there is a lack of medicine, Li Ke successfully treated thousands of patients with severe heart failure with this formula, but this formula has not been commonly used in modern society. Therefore, this paper discusses the treatment of chronic heart failure with the Pogejiuxin Decoction by combining the theory of circular motion, and broadens the idea of dialectical application from the drug mechanism and the characteristics of the formula.

Teaching Design of Experimental Chinese Medicine Based on BOPPPS Model

WU Xin, LI Bai-kun, SHENG Hong-mei, JIA Xue-zhao, GAO Fang

2025, 43(5):  103-107. 

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Bridge-in, Objective, pre-assessment, participatory learning, post-assessment, summary(BOPPPS) teaching mode is a new teaching method, which is widely used in the teaching of various subjects. Based on the analysis of the problems existing in the teaching process of Experimental Chinese Medicine, this paper takes the effect of Shengmai SAN on anoxic mice under normal pressure as an example to discuss how to apply BOPPPS model to the teaching design of Experimental Chinese Medicine, and points out the guiding and reference significance of this model to the teaching reform of Experimental Chinese Medicine.

Application of Tutorial System Combined with PBL and CBL Teaching Methods in Standardized Training of Resident Neurology Physicians

LI Jian, WANG Yan-qiang

2025, 43(5):  108-111. 

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Objective To explore the application effect of the tutorial system combined with problem-based teaching method(PBL) and case-based teaching method(CBL) on the standardized training of neurology residents. Methods Physicians studying in the Department of Neurology, Affiliated Hospital of Shandong Second Medical University from September 2022 to August 2023 were selected as study subjects. According to Random number method they were divided into observation group and control group. The observation group adopted the tutorial system+PBL+CBL teaching method, while the control group adopted the PBL+CBL teaching method. Then the theory and practice of the two groups were assessed, and the degree of satisfaction and interest were investigated. Results Compared with the control group, the theoretical test scores, clinical practice test scores, satisfaction and/or interest degree of the observation group were higher than those of the control group, and the differences were statistically significant (P<0.05). Conclusion The tutorial system combined with PBL and CBL teaching can significantly improve students’ assessment results, learning effects and teaching satisfaction,which is conducive to the improvement of clinical teaching quality.

Investigation on the Status of Vaccine Cold Chain Storage and Transportation Equipment in Qingdao's Licang District in 2023

DU Hui-qin, WANG Qiu-fen

2025, 43(5):  115-118. 

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Objective To investigate and analyze the status of vaccine cold chain storage and transportation equipment in Licang District, Qingdao City, in 2023. Methods The study targeted all units with vaccine cold chain storage and transportation equipment in Licang District, Qingdao City, from January 2023 to December 2023, including hospitals, community health service centers vaccination clinics, and district disease control centers. Relevant data were collected to statistically analyze the number of units participating in the survey, the average number of cold chain storage and transportation equipment in different types of units, the average service life of the equipment, and the configuration rate of automatic temperature monitoring devices in the equipment. Results A total of 33 institutions were surveyed: 5 hospital obstetric clinics (15.15%), 27 community health service center vaccination clinics (81.82%), and 1 disease control center (3.03%). Among the 5 hospital obstetric clinics, there are 5 regular refrigerators with an average service life of (7.01±1.58) years; and 5 small refrigerators for vaccination stations with an average service life of (7.58±1.62) years.The 27 community health service center vaccination clinics include 57 regular refrigerators with an average service life of (7.25±1.51) years; 86 smart refrigerators with an average service life of (3.22±1.11) years; 1 low-temperature freezer with a service life of 7 years; 120 cold storage boxes with an average service life of (4.97±2.19) years; and 83 small refrigerators for vaccination stations with an average service life of (4.24±1.67) years. The disease control center includes 2 regular cold storage units with an average service life of 7.5 years; 1 low-temperature freezer with a service life of 10 years; 43 cold storage boxes with an average service life of (5.12±1.02) years; and 1 cold chain transport vehicle with a service life of 13 years. The configuration rate of automatic temperature monitoring devices for regular refrigerators, smart refrigerators, low-temperature freezers, cold storage boxes and cold chain transport vehicles in the region was 100%, with a temperature measurement accuracy of ±0.5 ℃. Conclusion In 2023, the vaccine cold chain storage and transportation equipment in Licang District, Qingdao City, met the requirements for vaccine delivery in the region and showed a relatively fast update rate. For institutions with fewer devices, it is recommended to consider increasing the types and quantities of equipment to meet higher storage and transportation demands. It is also suggested to strengthen equipment maintenance and regular updates to ensure the effectiveness and safety of the vaccine cold chain.

Application of Feeding Detail Management in Eating Safety in Children With Cerebral Palsy

CHEN Guo-wei, TANG Ting-ting, GE Ya-shu, ZHOU Shan-shan

2025, 43(5):  119-122. 

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Objective To investigate the effect of feeding detail management in the eating safety of children with cerebral palsy and dysphagia. Methods A total of 56 Children with cerebral palsy with dysphagia in the Department of Pediatric Rehabilitation, Zhongda Hospital, Southeast University from April 2022—March 2024 were randomly sampled and divided into control group and observation group. There were 28 cases in each group, the control group was given routine feeding care and oral sensorimotor training, and the observation group was given feeding detail management, and the incidence of unsafe eating events, feeding ability and nutritional status were compared between the two groups before the intervention and after 6 months of intervention. Results The incidence of unsafe eating events in the observation group was lower than that in the control group, statistically significant(P<0.05). And the improvement in feeding ability was higher than that in the control group, statistically significant(P<0.05). The difference in body mass index and triceps subcutaneous fat thickness in the observation group was higher than that in the control group, statistically significant(P<0.05). Conclusion Feeding detail management can help improve the eating safety, feeding ability and nutritional status of children with cerebral palsy dysphagia.

The Impact of Comfort Care Guided by the 1+3+X Traditional Chinese Medicine Nursing Model and the Theory of Combined Incentives on the Rehabilitation of Postoperative Patients With Chronic Sinusitis

DUAN Wen-ping, ZHANG Feng-ying

2025, 43(5):  122-126. 

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Objective The present study aims to evaluate and validate the application effects of the "1+3+X" traditional Chinese medicine (TCM) nursing model in the perioperative period of nasal endoscopic surgery for patients with chronic sinusitis and its influence on patient rehabilitation. Methods A total of 80 patients with chronic sinusitis who underwent nasal endoscopic surgery in our hospital from June 2022 to June 2023 were selected as the study sample. Using a random number table method, patients were evenly divided into a control group and an experimental group, with 40 patients in each group. The control group received routine nursing care during the perioperative period,the experimental group implemented a 1+3+X traditional Chinese medicine characteristic nursing model on the basis of routine nursing. The effects were assessed by comparing data between the two groups in terms of nasal pain intensity, comfort level, and nursing satisfaction. Results Before the intervention, the pain scores were different (P>0.05). After the intervention, the pain scores gradually decreased over time, and the test group was lower at 24 h and 48 h than the control group, which was significant (P<0.05). The comfort and nursing satisfaction scores were higher than the control group, significant (P<0.05). Conclusion Through this study,implementing the‘1+3+X’TCM nursing model during the perioperative period of nasal endoscopic surgery for patients with chronic sinusitis can not only effectively reduce the incidence of postoperative complications but also significantly alleviate postoperative pain,improve nasal symptoms,and promote early patient recovery.This nursing model demonstrates high clinical application value and is worthy of promotion and application.

Application Value of Preemptive Nursing in Prevention of Deep Venous Thrombosis of Lower Extremity in Patients with Acute Stroke

WANG Hui, WANG Fang

2025, 43(5):  126-129. 

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Objective To explore the application of preemptive nursing in the prevention of deep venous thrombosis of lower extremity in patients with acute stroke. Methods A total of 60 patients with acute stroke who visited Xuzhou Central Hospital from January 2021 to May 2024 were selected as the study objects and divided into control group (n=30) and observation group (n=30) by random number table method. The control group implemented routine nursing mode, and the observation group implemented pre-plan nursing mode. Lower extremity skin temperature, leg temperature, blood coagulation function and lower extremity venous thrombosis were compared between the two groups. Results After intervention, the lower extremity skin temperature and leg circumference of the two groups were increased, while the observation group was lower than the control group, the difference was statistically significant(P<0.05). After intervention, the levels of prothrombin time (PT) and activated partial prothrombin time (APTT) in 2 groups were decreased, and the observation group was higher than the control group,, the levels of D-dimer (D-D) and fibrinogen (FIB) in both groups were increased, while the observation group was lower than the control group, the difference was statistically significant(P<0.05). The incidence of lower extremity venous thrombosis in observation group was lower than that in control group, and the difference was statistically significant(P<0.05). Conclusion In patients with acute stroke, preemptive nursing can effectively reduce lower extremity temperature, avoid excessive leg swelling, adjust coagulation index, and reduce the risk of complications.

To Evaluate the Effect of Surgical Approach (Transanal and Transabdominal) on the Prognosis and Quality of Life of Patients with Early Rectal Cancer: A Retrospective Cohort Study to Evaluate R0 Resection Rate and Bowel Function Outcome

GUO Hai-long, HAN Yu-tian, QU Wei, BAI Xue-feng, WU Hao, LIU Xiao-ming, WANG Zhong-yan

2025, 43(5):  171-174. 

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Objective To investigate the effect of different surgical approaches on prognosis and quality of life in early stage rectal cancer tumors. Methods A retrospective analysis was performed on 60 patients with rectal cancer admitted to the Third Affiliated Hospital of Qiqihar Medical College from 2021.1 to 2023.6.All patients underwent elective radical resection of rectal cancer. According to different surgical approaches, they were divided into control group (abdominal approach, n=30) and observation group (anal approach, n=30). The complete (R0) resection rate, intestinal function outcome and quality of life were compared between the two groups. Results The R0 resection rate in the observation group was significantly higher than that in the control group (93.33% vs 73.33%) (P<0.05); there was no statistically significant difference in the Gastrointestinal Symptom Rating Scale (GSRS) scores between the two groups before surgery (P>0.05), and one week after surgery, the GSRS scores of the observation group were significantly lower than those of the control group (P<0.05); there was no statistically significant difference in the Spitzer Quality of Life Index (SQLI) scores between the two groups before surgery (P>0.05), and two years after surgery, the SQLI scores of the observation group were significantly higher than those of the control group (P<0.05). Conclusion The rectal cancer resection through the anal approach is better than the abdominal approach, and the R0 resection rate is 93.33%. The postoperative intestinal function of the patients recovered well, which can effectively improve the survival rate and quality of life of the patients.intestinal function