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Table of Content

    01 September 2024, Volume 42 Issue 17
    Screening of Energy Metabolism Genes Related to the Prognosis of Hepatocellular Carcinoma and Construction of Prognosis Prediction Model
    WU Yi-jiang, PENG Liang, XIE Bin-hui
    2024, 42(17):  1-4. 
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    Objective To construct a prognostic prediction model for hepatocellular carcinoma (HCC) based on energy metabolism-related genes and evaluate its predictive ability for HCC patient outcomes. Methods We obtained expression data and clinical information for HCC and normal liver tissues from the TCGA database. Prognosis-related differentially expressed genes were identified using the R limma package and univariate analysis. These data were used as the training set to construct a LASSO Cox regression prognostic model, and the ICGC database was used for model validation. GO and KEGG methods were applied to analyze differentially expressed genes in the high- and low-risk groups. We assessed the predictive ability of the model using Receiver Operating Characteristic (ROC) curves, survival analysis, and multivariate Cox regression. The ssGSEA method was used to perform risk analysis on differential genes between the two groups. Results Analysis of the TCGA database identified five risk genes (IVD, CYB5R3, LDHA, NQO1, and UGDH) for constructing the prognostic model. The risk rating formula was: -0.021IVD + 0.005CYB5R3 + 0.005LDHA + 0.001NQO1 + 0.002*UGDH. ROC curves for 1-, 2-, and 3-year survival rates in both TCGA and ICGC databases had areas under the curve (AUC) exceeding 0.65. Survival analysis indicated that the low-risk group had significantly better outcomes than the high-risk group. Risk scores were confirmed as independent prognostic indicators in both univariate and multivariate Cox analyses. Differential genes between high- and low-risk groups were mainly involved in retinal metabolism and cytochrome P450 pathways. Additionally, there is a statistically significant difference in immune function between the two groups(P<0.05). Conclusion The HCC prognostic model based on energy metabolism genes demonstrates good predictive performance. These energy metabolism genes provide new targets for HCC targeted therapy.
    A Qualitative Study on the Influencing Factors of Vision Health Literacy in Families among Pupils with Simple High Myopia
    GAO Shu-ping, WANG Shuang-yue, YIN Hui, YANG Jin-fang
    2024, 42(17):  5-8. 
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    Objective Investigate the current status of visual health literacy in families of primary school students with simple high myopia, explore the underlying family-related factors behind the progression of myopia, and improve the level of visual health literacy in their families. Methods From June 2022 to November 2022, 11 cases of primary school students with simple high myopia and their parents who visited the First People's Hospital of Xiangyang City were selected as the research objects. Semi-structured in-depth interviews and questionnaires were conducted. Results The content of the interviews yielded three aspects: ①Student and parental factors, including disease perception, parent-child communication barriers, lack of knowledge, and misconceptions; ②Economy-related factors related to vision; ③Social security factors related to vision. In addition, the questionnaire results showed that learning-related factors might be the main cause of most students' vision problems, and the highest item of parental concern about video usage was students' incorrect eye behaviors. Conclusion The family visual health literacy of primary school students with simple high myopia is related to various factors. Improvement efforts should focus on psychological counseling, popular science education, medical security, market supervision, etc., to enhance the awareness of visual protection for primary school students and parents and establish a good family visual environment.
    Clinical Study on the Treatment of Malignant Pleural Effusion by Time-Selected External Application of Jinlong Nituhuang Powder Combined with Pleural Perfusion under the Guidance of Nazi Method
    SHAN Lan, SONG Fang-lei, CHEN Yuan-yuan
    2024, 42(17):  9-12. 
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    Objective The aim of this study was to evaluate the efficacy and safety of time-selected external application of Jinlong Nituhuang Powder combined with thoracic perfusion under the guidance of Nazi method. Methods This study was a prospective, randomized, controlled trial. The efficacy was evaluated according to evaluation criteria for the treatment of pleural effusion, the improvement of TCM symptoms and the EORTC QLQ-C30. Results The study included 90 eligible patients. They were randomly divided into treatment group (n=45) and control group (n=45). The difference of total effective rate between the two groups was statistically significant (P<0.05). The scores of TCM symptoms in both groups were lower after treatment than before treatment, and the difference was statistically significant compared with that in this group (P<0.05), and the reduction of treatment group was better than control group (P<0.05). The physical function status, general health status, fatigue and shortness of breath were significantly improved in the treatment group. No patients had skin allergy, chest tightness and other adverse reactions. Conclusion Under the guidance of Nazi method, Jinlong Nituhuang Powder combined with pleural perfusion has significant therapeutic effect on MPE, can significantly improve patients’ quality of life and with high safety.
    The Application of Traditional Chinese Fitness Gong in Improving Mild Cognitive Dysfunction
    CHENG Peng-fei, QIAN Chun-sheng
    2024, 42(17):  13-16. 
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    Mild cognitive impairment (MCI) is considered to be a pathological condition that predates Alzheimer's disease and is characterized by impairment of cognitive function without impaired ability of daily living. In recent years, exercise therapy has been cost-effective and effective in improving mild cognitive dysfunction with few side effects, but current studies have mostly focused on the field of modern aerobic exercise. From the perspective of different traditional Chinese fitness exercises, such as Taijiquan and Baduanjin, this paper explores the intervention effects on patients with mild cognitive dysfunction and sorts out relevant research progress and limitations, with a view to providing theoretical basis for subsequent studies.
    Application Effect of Drug Canister Therapy in Lung Cancer Patients with Qi-Yin Deficiency
    XU Yi, GAO Xia, DI Kan-xiang, ZHU Qing-qing, SHI Zhi-xue
    2024, 42(17):  20-23. 
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    Objective To investigate the effect of drug canning therapy on lung cancer patients with Qi-yin deficiency. Methods A total of 80 patients with Qi-yin deficiency lung cancer admitted to our hospital from October 2022 to June 2023 were selected as research objects, and were divided into observation group and control group by random number table method, with 40 cases in each group. The control group received routine care, and the observation group added medicine pot therapy on the basis of control group. The changes of TCM syndrome score, pain numerical scale (NRS) score, hemorheology, cancer fatigue degree and quality of life were compared between the two groups. Results There was no significant difference in TCM syndrome scores related to primary and secondary diseases between the two groups before intervention (P>0.05). After intervention, TCM syndrome scores related to primary and secondary diseases were decreased between the two groups, and the observation group was lower than the control group (P<0.05). There was no significant difference in NRS scores between the two groups before intervention (P>0.05), and the scores of the two groups were decreased after intervention, and the observation group was lower than the control group (P<0.05). There was no significant difference in hemorheological indexes between the two groups before intervention (P>0.05). After nursing, the specific viscosity of plasma, the specific viscosity of high cut whole blood and the specific viscosity of low cut whole blood were decreased between the two groups, and the observation group was lower than the control group (P<0.05). There was no significant difference in PFS-R and WHOQOL-BREF scores between the two groups before intervention(P>0.05). After intervention, PFS-R scores of the two groups were decreased, and the observation group was lower than the control group, and the WHOQOL-BREF score was increased, and the observation group was higher than the control group (P<0.05). Conclusion Drug pot therapy can improve the TCM symptoms of patients with Qi-yin deficiency lung cancer, reduce the degree of cancer-induced pain, improve the level of hemorheology, reduce the degree of cancer-induced fatigue, and enhance the quality of life of patients.
    Efficacy and Safety of Four Hole Laparoscopy Surgery for Colorectal Cancer
    TANG Bo-hua, PANG Xiao-xi, YAO Qiu-yan
    2024, 42(17):  40-42. 
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    Objective To explore and analyze the efficacy and safety of four hole laparoscopy for colorectal cancer. Methods A total of 86 cases of patients with colorectal cancer who underwent Elective surgery in People's Hospital of Dali Bai Autonomous Prefecture from January 2020 to January 2023 were selected as the study subjects. Accorded to random number table, 86 patients were divided into the four hole group (43 cases) and the traditional group (43 cases). The traditional group were treated with traditional open surgery, and the four hole group were treated with four hole Laparoscopy. The effectiveness and safety of the two groups were recorded. Results The surgical time, intraoperative bleeding, postoperative first exhaust time, postoperative first defecation time, postoperative first meal time, and postoperative hospitalization time of the four hole group were significantly shorter than those of the traditional group (P<0.05). The visual analog pain scale (VAS) scores of the four hole group on postoperative day 1, 7, and 14 were lower than those of the traditional group, and the difference was statistically significant (P<0.05). The incidence of intestinal obstruction, incision infection, anastomotic leakage, urinary retention, pulmonary infection and other complications 14 days after operation in the four hole group was lower than that in the traditional group, with a statistically significant difference (P<0.05). The serum levels of superoxide dismutase and malondialdehyde in the two groups were higher on the 14th day after surgery than on the 1st day before surgery, and lower on the 1st day before surgery. The serum levels of superoxide dismutase and malondialdehyde in the four well group were statistically significant compared to the traditional group on the 14th day after surgery (P<0.05). The general health status, mental health, physical pain, vitality index, emotional function, and other quality of life scores of the four hole group were higher than those of the traditional group 14 days after surgery, and the difference was statistically significant (P<0.05). Conclusion Four hole laparoscopy for colorectal cancer has good safety and effectiveness, which can alleviate patients' pain, promote patients' rehabilitation, reduce the incidence of complications, improve oxidative stress response, and improve patients' quality of life.
    Early Diagnostic Value of CT Combined with Magnetic Resonance Imaging in Bone and Vascular Changes in Diabetic Foot Patients
    WANG Shu-qiao
    2024, 42(17):  47-49. 
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    Objective To explore the early diagnostic value of CT combined with magnetic resonance imaging (MRI) in diabetic foot bone and vascular changes. Methods A total of 80 patients with diabetic foot admitted to Eastern Theater Air Force Hospital, People's Liberation Army from January, 2021 to December, 2022 were selected as the research objects, and all of them were examined by CT and MRI. The CT and MRI of diabetic foot were observed, and the diagnostic results of single and combined detection for diabetic foot bone and vascular changes were compared. With digital angiography (DSA) as the gold standard, the diagnostic efficacy of single and combined detection for lower extremity arterial diseases was analyzed. Results ①The detection rate of CT combined with MRI was higher than that of CT examination for soft tissue swelling, higher than that of MRI examination for bone end bone destruction, and higher than that of CT and MRI examination for osteoporosis and neuropathic osteoarthropathy, and the difference was statistically significant (P<0.05). ②The results of CT combined with MRI in detecting arterial stenosis of lower limbs are in good agreement with those of DSA (kappa=0.935). ③The sensitivity, accuracy and negative predictive value of 3) CT combined with MRI in the diagnosis of diabetic lower extremity vascular stenosis were higher than those of single detection, and the difference was statistically significant (P<0.05). Conclusion CT combined with MRI can detect the changes of diabetic foot bone and blood vessels more comprehensively and accurately. Compared with single detection, CT combined with MRI has higher sensitivity, accuracy and negative predictive value in the diagnosis of lower extremity arterial stenosis.
    Application of Drug Coated Balloon Combined with Rivaroxaban in the Treatment of Coronary Bifurcation Lesions
    LIU Guo-xing
    2024, 42(17):  53-56. 
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    Objective To analyze the clinical effect of drug coated balloon combined with Rivaroxaban in the treatment of coronary bifurcation lesions. Methods A total of 68 patients with coronary bifurcation lesions in Ningde City Hospital affiliated to Ningde Normal University from October 2020 and October 2022 were selected for the study, they were randomly divided into a control group and an observation group using a random number table method, and 34 cases in each group. During the interventional therapy of both groups, the control group applied Rivaroxaban treatment, and the observation group used drug-coated balloon combined with Rivaroxaban treatment to compare the clinical treatment effect of the two groups. Results The incidence of adverse cardiovascular events in the observation group was lower than that in the control group, with significant differences between the two groups (P<0.05). The side branch stenosis rate and side branch occlusion rate of the observation group patients were lower than those of the control group, and the difference was statistically significant (P<0.05). The vWF, Ang II, hsCRP, and HbAlc levels in the observation group were lower than those in the control group, with statistically significant differences (P<0.05). The physical and mental health scores of the observation group patients were higher than the control group, and the difference was statistically significant (P<0.05). Conclusion drug coated balloon combined with Rivaroxaban in the treatment of coronary bifurcation lesions has good effect, it can effectively reduce the incidence of adverse cardiovascular events, improve the clinical efficacy, reduce the rate of postoperative stenosis and edge occlusion, improve the quality of life of patients, play a positive application value.
    Research Progress on Transcranial Direct Current Stimulation to Regulate Mind Wandering
    HUANG Jia-hao, YE An-qi, CHEN Jun-jie, HUANG Hao-yuan, XU Biao-ping, LU Jun-yue, WEN You-liang
    2024, 42(17):  67-70. 
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    mind-wandering, can indirectly or directly affect the brain's attention to the task of performing the task in the moment. How to control distraction, reduce negative emotions by reducing distraction tendencies, and alleviate persistent anxiety, so as to alleviate or solve mental illness is a hot issue today. Transcranial direct current stimulation (tDCS) is a non-invasive and reversible non-invasive brain stimulation technique that can be used to modulate the excitability of the human central nervous system. In this paper, the mechanism, application scheme, limitations, and future prospects of tDCS are reviewed.
    Progress of Clinical Research on Red Yeast Rice(RYR)
    YU Feng-Chun, Bi Qi
    2024, 42(17):  71-75. 
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    Red yeast rice(RYR) is a traditional Chinese medicine. Modern studies have found that Monaclin K contains RYR, which has the effect of lowering blood lipids. Therefore, statins developed and developed have played an obvious role in reducing blood lipids, reversing and delaying atherosclerotic plaques, and preventing and treating cardiovascular diseases, and have been recommended by various domestic and foreign guidelines. It is because of the effective use of statins that attention and research have been paid to RYR containing Monaclin K. In this paper, clinical research literatures related to RYR preparations, including drugs and health care foods, were collected, and the effectiveness, safety and precautions of clinical trials were reviewed, so as to provide reference for the use of red yeast rice preparations.
    Exploration of Teaching Reform in the Course of Introduction to Traditional Chinese Medicine
    ZENG Mei-yan, REN Bao-ping, YU Chang, ZHOU Shun-hua, ZHONG Mei-qi, XIONG Meng, GAO Qing, WANG Xiao-juan, SONG Hou-pan
    2024, 42(17):  76-79. 
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    Introduction to Traditional Chinese Medicine is a compulsory basic course in traditional Chinese medicine for non undergraduate students majoring in traditional Chinese medicine in higher education institutions. It is an important carrier course for cultivating talents in traditional Chinese medicine. With the development of society and the continuous progress of the medical field, the education of Introduction to Traditional Chinese Medicine needs to be constantly updated and improved to meet the needs of modern medical education. This article studies and analyzes the challenges faced by the traditional teaching model of Introduction to Traditional Chinese Medicine, and proposes corresponding reform suggestions, such as updating textbook content, utilizing modern educational technology, conducting experimental training teaching, emphasizing student feedback and teaching evaluation, strengthening the cultivation of teacher professional quality, and strengthening policy support. The aim is to improve the quality of education in Introduction to Traditional Chinese Medicine and cultivate more composite TCM talents.
    The Impact of 4R Crisis Management on the Implementation of Prevention and Control Measures for Multidrug-Resistant Bacterial Infections and the Incidence of Infection
    XIE Xiu-zhang
    2024, 42(17):  89-91. 
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    Objective To explore the impact of 4R crisis management on the implementation of prevention and control measures for multidrug-resistant bacterial infections and the incidence of infections. Methods A total of 370 medical workers from Wujin Hospital affiliated to Jiangsu University from April 2020 to April 2023 were selected as the study subjects and divided into two groups according to different management plans. 180 control group received routine training on multidrug-resistant bacteria, and 190 study group received 4R crisis management on the basis of the control group. Before and after the intervention, the knowledge and implementation of the prevention and control measures of multi-drug-resistant bacteria, hand hygiene and multi-drug-resistant bacteria infection in different samples were compared between the two groups. Results There was no significant difference in the knowledge of prevention and control of multidrug-resistant bacteria in the two groups before intervention (P>0.05). After intervention, the knowledge of medical staff in the study group was higher than that in the control group (P<0.05). The hand hygiene compliance of medical staff in different positions in the study group was higher than that in the control group (P<0.05). There was no difference in the incidence of multidrug-resistant bacteria infection between the two groups before intervention (P>0.05). After intervention, the incidence of multidrug-resistant bacteria infection in the study group (3.60%) was lower than that in the control group (8.40%) (P<0.05). Conclusion The 4R crisis management model has positive value in improving the implementation of prevention and control measures for multidrug-resistant bacterial infections among medical workers. It can reduce the detection rate of multidrug-resistant bacteria in patient fluids. It has good promotion and application value.
    The Application Effect of Hierarchical Chain Based Medical Care Collaborative Nursing in Pediatric Rotavirus Enteritis
    WEI Xiao-cui, LIU Yi-jin
    2024, 42(17):  92-95. 
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    Objective To explore the application effect of hierarchical chain based medical care collaborative nursing in the treatment of pediatric rotavirus (RV) enteritis. Methods A total of 86 children with RV enteritis admitted to Laiyang Central Hospital in Yantai City from July 2022 to July 2023 were randomly divided into two groups with 43 cases each. The control group received routine care, while the research group received hierarchical chain medical and nursing collaborative care. Compare the nursing effectiveness, compliance, clinical indicators, and nursing satisfaction between the two groups. Results The total effective rate of nursing in the research group was higher than that in the control group (P<0.05). The compliance of children in the research group was higher than that in the control group (P<0.05). The research group showed lower fever reduction, disappearance of diarrhea, cessation of vomiting, and hospital stay compared to the control group (P<0.05). The satisfaction scores of nursing skills, health education, psychological care, service attitude, and treatment effectiveness among the family members of the research group were higher than those of the control group (P<0.05). Conclusion The hierarchical chain of medical and nursing collaborative care has a significant nursing effect in pediatric RV enteritis. It can not only improve the patient's nursing compliance, promote the disappearance of symptoms, reduce hospitalization time, but also improve the satisfaction of the patient's family and promote early recovery of the patient.
    Observation on the Effectiveness of Hospital Led Home Cardiac Rehabilitation Nursing in Patients with Heart Failure
    ZHU Wei-ning, ZHANG Yun-yun
    2024, 42(17):  96-98. 
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    Objective To explore and observe the effectiveness of hospital led home cardiac rehabilitation nursing in patients with heart failure. Methods From February 2021 to February 2023, 70 patients with heart failure diagnosed and treated in the First People's Hospital of Tianshui City, Gansu Province, were selected as the study objects.Accorded to the 1:1 random number table method, 70 patients were divided into the observation group of 35 cases and the control group of 35 cases. The control group was given routine nursing, and the observation group was given hospital-led home cardiac rehabilitation nursing on the basis of the control group. The nursing observation time of the two groups was 2 months. The cardiac function, lipid level, physical function and self-care ability of the two groups were compared. Results After 2 months of nursing care, the left ventricular end diastolic volume and left ventricular end systolic volume of both groups were significantly lower than before nursing care (P<0.05). After 2 months of nursing care, the left ventricular end diastolic volume and left ventricular end systolic volume of the observation group were also significantly reduced compared to the control group (P<0.05). After 2 months of care, the triglycerides and total cholesterol levels in both groups were significantly lower than before care (P<0.05). After 2 months of care, the triglycerides and total cholesterol levels in the observation group were also significantly lower than those in the control group (P<0.05). The 6-minute walking distance and 30 second arm flexion test results of the two groups after 2 months of nursing care were also significantly higher than those before nursing care (P<0.05), and the results of the 10 sit stereoscopic tests were also significantly lower than those before nursing care (P<0.05). The above physical function indicators of the observation group after 2 months of nursing care were also significantly different from those of the control group (P<0.05). The self-care ability scores of both groups after 2 months of nursing care were significantly higher than those before nursing care (P<0.05), and the self-care ability scores of the observation group were also significantly higher than those of the control group after 2 months of nursing care (P<0.05). Conclusion The application of hospital led home cardiac rehabilitation nursing in patients with heart failure can improve heart function, reduce blood lipid levels, improve physical function, and enhance patients' self-care ability.
    The Impact of Detailed Intervention Combined with High-Quality Nursing on the Quality of Life and Negative Emotions of Patients with Sequelae of Cerebrovascular Accidents
    XU Yun
    2024, 42(17):  106-108. 
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    Objective To explore the effectiveness of detailed intervention combined with high-quality care for patients with sequelae of cerebrovascular accidents. Methods From May 2021 to May 2023, 80 patients with sequelae of cerebrovascular accidents admitted to Wuxi Rehabilitation Hospital were selected as the research subjects of this article. They were randomly divided into an intervention group and a control group based on their hospitalization number, with 40 patients in each group. The control group received routine nursing interventions, while the intervention group received detailed and high-quality nursing interventions, The psychological status of patients was evaluated using the Self-rating Anxiety Scale (SAS) and the Self-rating Depression Scale (SDS). The quality of life of patients after treatment was evaluated using the SF-36 scale, and nursing satisfaction was compared between the two groups of patients. Results There was no statistically difference in SAS and SDS scores between the two groups of patients before nursing (P>0.05). After nursing intervention, the SAS and SDS scores of both groups of patients decreased, and after nursing intervention, the SAS and SDS scores of the intervention group were lower than those of the control group (P<0.05); There was no statistically difference in physiological function, physiological function, physical pain, and vitality scores between the two groups of patients before nursing intervention (P>0.05). After nursing intervention, the physiological function, physical pain, and vitality scores of the two groups of patients decreased, and after nursing intervention, the scores of the intervention group in the above dimensions were higher than those of the control group (P<0.05); The nursing satisfaction of patients in the intervention group was 95.00%, while the nursing satisfaction of patients in the control group was 75.00%. The nursing satisfaction of patients in the intervention group was higher than that of the control group (P<0.05). Conclusion The combination of detailed intervention and high-quality care during the treatment of sequelae of cerebrovascular dependence can significantly improve the treatment effect, help patients reduce negative emotions, improve their living standards, and have significant application value.
    Effect of Two-way Quality Feedback Management on Liver Cirrhosis Complicated with UGB and Its Influence on SRSS Score of Patients
    LYU Jin-hong
    2024, 42(17):  109-112. 
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    Objective To explore the effect of two-way quality feedback management on liver cirrhosis complicated with upper gastrointestinal bleeding (UGB) and its influence on sleep self-rating scale (SRSS) score. Methods A total of 100 patients with cirrhosis and UGB admitted to Tai 'an Hospital of Traditional Chinese Medicine from October 2020 to November 2023 were selected as the research objects. According to the random number table method, they were divided into the control group (50 cases) and the observation group (50 cases). The control group received routine nursing intervention methods, and the observation group received routine nursing +two-way quality feedback management method. The intervention effect, improvement of self-management ability, psychological state and sleep quality were compared between the two groups. Results Compared with the control group, the observation group had significant reductions in hemostasis time, length of hospital stay, hospitalization cost, Incidence of rebleeding during hospitalization, self-rating anxiety scale (SAS) score, self-rating depression scale (SDS) score, and SRSS score (P<0.05),while the liver cirrhosis self-management behavior scale score increased significantly (P<0.05). Conclusion Two-way quality feedback management has a significant intervention effect on liver cirrhosis patients with UGB, which can effectively improve the self-management ability of patients,improve their mental state and sleep quality, and shorten the rehabilitation process.
    Application of Green Mode and Early Plantar Stress Stimulation in Patients with Calcaneal Fractures
    ZHU Chun-hua, FENG Hui, YANG Tian-yu
    2024, 42(17):  147-150. 
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    Objective To explore the effect of applying Green's mode and early plantar stress stimulation in patients with calcaneal fractures. Methods A total of 86 patients with calcaneal fractures from July 2020 to June 2023 who were admitted in Liaocheng People's Hospital were selected, and randomly divided into the intervention group (n=43, combination of Green mode and early plantar stress stimulation intervention ) and the control group (n=43, routine care). The exercise compliance, pain level, affected foot function, and daily living ability in both groups were compared. Results In the exercise compliance, in comparision of the control group, the intervention group was higher (P<0.05). After intervention, VAS scores in both groups were decreased (P<0.05), and in comparision of the control group, the intervention group was lower (P<0.05). After intervention, AOFAS scores in both groups were increased (P<0.05), and in comparision of the control group, the intervention group was higher (P<0.05). After intervention, BI scores in both groups were increased (P<0.05), and in comparision of the control group, the intervention group was higher (P<0.05). Conclusion :The combination of Green's mode and early plantar stress stimulation can improve exercise compliance, alleviate pain, and promote improvement of foot function and daily living ability in patients with calcaneal fractures.
    Treatment of pediatric chalazion by Prof. Wang Yinglin with Qingzhi Synthesis
    LI Qi, WU Jian-jun, DING Dan-dan, CHENG Qiu
    2024, 42(17):  160-162. 
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    Pediatric chalazion is one of the common eye diseases in clinical practice. It not only affects children's normal vision but also has a cosmetic impact, significantly affecting the daily lives of affected children. Western medical treatment for this condition often involves the use of corticosteroids or surgical excision, which can be resistant and carries some risk due to its invasive nature, making it less acceptable to the families of affected children. Some children with chalazion may experience recurrent episodes, causing ongoing distress to both the children and their families. Traditional Chinese medicine (TCM) can serve as a treatment method to help alleviate symptoms and improve immune system function. TCM approaches for treating pediatric chalazion typically include Chinese herbal medicine, acupuncture, tuina massage, and dietary therapy. The author has had the privilege of studying under the renowned TCM practitioner Wang Yinglin for several years and has achieved significant success in treating chalazion using his family's proprietary "Qing Zi He Formula."
    Application Effect of Cefuroxime Sodium and Ceftizoxime Sodium in the Treatment of Children with Acute Bronchial Pneumonia and VCAM-1, IFN- γ Horizontal Impact
    XU Cui-ping, CHEN Chong
    2024, 42(17):  169-171. 
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    Objective Objective to investigate the application effect of cefuroxime sodium and ceftizoxime sodium in the treatment of children with acute bronchial pneumonia and the animal vascular cell adhesion molecule-1 (VCAM-1) and its clinical significance γ Interferon (IFN-γ) Horizontal impact. Methods All 82 children with bronchopneumonia admitted to Hancheng Maternal and Child Health Hospital from August 2021 to July 2023 were selected for retrospective analysis, and randomly divided into cefuroxime sodium group and ceftizoxime sodium group, 41 cases in each group. All children were treated with routine maintenance of water electrolyte, acid-base balance, sputum suction, heat clearing, asthma relieving, cough relieving and other symptomatic treatment, and were treated with budesonide atomization inhalation and azithromycin oral treatment. The children in Cefuroxime Sodium group were given cefuroxime sodium intravenous drip on the basis of conventional treatment, while the children in ceftizoxime sodium group were given ceftizoxime sodium intravenous drip on the basis of conventional treatment. The disappearance time of pulmonary rales/wheezes, cough, total days of fever, imaging recovery time, VCAM-1 and IFN before and after treatment were compared between the two groups-γ, The expression levels of PCT and CRP were compared between the two groups. Results The disappearance time of pulmonary rales/wheezes, cough, total days of fever and imaging recovery time in Cefuroxime Sodium group were significantly lower than those in ceftizoxime sodium group (P<0.05); VCAM-1 and IFN of the two groups before treatment-γ. There was no significant difference in the expression levels of PCT and CRP between the two groups (P>0.05). After treatment, the levels of VCAM-1, PCT and CRP in the two groups were decreased, and the level of IFN in the cefuroxime sodium group was lower than that in the ceftizoxime sodium group-γ The serum level in Cefuroxime Sodium group was higher than that in ceftizoxime sodium group (P<0.05); No severe adverse reactions such as renal function injury and blood system injury occurred in the two groups, and there was no significant difference in adverse reactions such as nausea and vomiting, dizziness, skin allergy and diarrhea between the two groups (P>0.05). Conclusion Cefuroxime sodium is better than ceftizoxime sodium in the application of children with acute bronchial pneumonia, which can shorten the duration of symptoms, relieve the accumulation of inflammatory cytokines, reduce the body's inflammatory reaction, and has high safety.
    The Value of Urinary Metaphase Factor as A Non-Invasive Diagnostic Index of Bladder Cancer
    SUN Qi-yao, LIU Xu-dong, XIAO Yong-qi, MENG Fan-ke
    2024, 42(17):  172-175. 
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    Objective To analyze the application value of urinary medium factor in the diagnosis of bladder cancer. Methods From July 2019 to June 2023, 82 patients with bladder cancer in Xuecheng District People's Hospital and Zaozhuang Municipal Hospital were selected as group A, 82 patients with benign urinary system diseases in the same period of time were selected as group B, and 82 healthy subjects in the same period of time were selected as group C. Urine midterm factor test was performed in all three groups, and the differences in test results among the three groups were compared. The diagnostic value of urinary intermediate factor was evaluated by histopathological examination. Finally, the correlation between the clinical data of patients with bladder cancer and urine metaphase factors was observed, and the correlation analysis between clinical characteristics and urinary intermediate factor levels in patients with bladder cancer was analyzed by univariate analysis. Results Urine metaphase factor in group A was significantly higher than that in groups B and C, the difference was significant (P<0.05), urine metaphase factor in group B was higher than that in group C, the difference was significant (P<0.05). The diagnostic results of urinary mid-stage factor were 82 cases of bladder cancer, 16 cases missed diagnosis, and 6 cases misdiagnosed. The sensitivity of urinary mid-stage factor was 80.5%, the specificity was 90.2%, the accuracy was 87.0%, the positive predictive value was 80.5%, and the negative predictive value was 90.2%. There were significant differences in urinary medium factor levels among different tumor numbers, muscle invasiveness and lymph node metastasis in patients with bladder cancer (P<0.05). Conclusion Urinary medium term factor has high sensitivity and specificity in the diagnosis of bladder cancer, and can be used as an evaluation index for non-invasive diagnosis.
    Summary of Chief Physician Jing Ming’s Experience in Treating lumbar and Hip Myofascial Pain Syndromes with Tuina Techniques
    SU Feng, SHI Yun-Shan, LIU Yi, JING Ming
    2024, 42(17):  182-184. 
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    Lumbar gluteal myofascial pain syndrome is a common cause of low back pain, and Tui Na has unique advantages in treating this condition. The article summarises the special Tui Na techniques used by Dr Jing Ming in the treatment of lumbar gluteal myofascial pain syndrome. It describes in detail the operation steps, precautions and therapeutic features. This featured massage technique is an inheritance and innovation of the traditional massage technique, which can be used as a reference.
    The Effect of High-Intensity Focused Ultrasound on Residual Fibroids and Oxidative Stress in Patients with Uterine Fibroids
    WANG Yun, ZHAO Wen-yu
    2024, 42(17):  191-194. 
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    Objective To explore the effect of ultrasound-guided high-intensity focused ultrasound (HIFU) on the treatment of uterine fibroids and its impact on residual fibroids and oxidative stress. Methods 84 patients with uterine fibroids, admitted to Yantai Laiyang central hospital from August 2020 to August 2023, were randomly divided into two groups. The control group underwent laparoscopic myomectomy, while the study group received HIFU treatment. Surgical outcomes, complication rates, residual fibroid rates, and oxidative stress markers [malondialdehyde (MDA), advanced oxidative protein products (AOPP), reactive oxygen species (ROS)] were evaluated, and immune function markers [Tlymphocytes (CD3+, CD4+, CD4+/CD8+)] were also assessed into two groups. Results Compared with the control group, the study group had shorter surgical time, postoperative exhaust time, hospital stay, and less intraoperative bleeding, with statistically significant differences (P<0.05). Compared with the control group, the incidence of postoperative complications and residual fibroids in the study group were lower, and the difference was statistically significant (P<0.05). There was no statistically significant difference (P>0.05) in MDA, AOPP, and ROS levels between the two groups before surgery. However, compared to before surgery, the MDA, AOPP, and ROS levels in the two groups increased on the first day after surgery, and the difference was statistically significant (P<0.05). However, compared to the control group, the MDA, AOPP, and ROS levels in the study group were lower, and the difference was statistically significant (P<0.05). There was no statistically significant difference (P>0.05) in the comparison of CD3+, CD4+, and CD4+/CD8+between the two groups before surgery. Compared with before surgery, the levels of CD3+, CD4+, and CD4+/CD8+in the two groups decreased 1 day after surgery. However, compared with the control group, the levels of CD3+, CD4+, and CD4+/CD8+in the study group were higher, and the difference was statistically significant (P<0.05). Conclusion :Ultrasound-guided HIFU treatment of uterine fibroids has a low residual rate of fibroids and a low incidence of fibroids, which has little effect on oxidative stress and immune function, and is safe and effective.