Significance of Placental Pathology and Blood Flow Detection in Fetal Growth Restriction
WANG Hui, WEN Yu-jun
2023, 41(24):
170-174.
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Objective To explore the significance of placental pathology and blood flow in the detection of fetal growth restriction (FGR). Methods From May 2022 to March 2023, 90 pregnant women who were diagnosed with FGR in the First Hospital of Peking University Ningxia Women's and Children's Hospital and Yinchuan Maternal and Child Health Hospital were selected as the study group, and 90 healthy pregnant women who were treated at the same time in the above-mentioned medical institutions were selected as the control group. Placental blood flow dynamic monitoring was performed on the two groups of pregnant women at 32 weeks of gestation, and the pulsation index (PI) of placental blood flow at the above time points was recorded The blood flow resistance index (RI) and the ratio of systolic peak to end diastolic flow velocity (S/D) of umbilical artery were compared between groups. Then, according to the pathological results of placental blood perfusion of pregnant women in the study group, they were divided into group A (placental blood perfusion was poor, n=21) and group B (placental blood perfusion was normal, n=69). The differences of PI, RI, S/D values of pregnant women in the two subgroups were compared. Pearson correlation analysis was used to explore the PI, RI The correlation of S/D value, and the diagnostic efficacy of PI, RI, S/D value on FGR was calculated by drawing the subject curve. Results The PI, RI, S/D values of pregnant women in the study group were significantly higher than those in the control group (P<0.05). The PI, RI and S/D values of pregnant women in group A were significantly higher than those in group B (P<0.05). Pearson correlation analysis showed that the PI value of FGR pregnant women was significantly positively correlated with their RI value and S/D value (r=0.435, P<0.05; r=0.432, P<0.05), and the RI value of FGR pregnant women was also significantly positively correlated with their S/D value (r=0.781, P<0.05). The diagnostic efficacy of PI, RI and S/D values on FGR was calculated by drawing ROC curves. The AUC was 0.674 (95% CI=0.589~0.759, P<0.05), 0.901 (95% CI=0.854~0.949, P<0.05) and 0.727 (95% CI=0.648~0.806, P<0.05), respectively. Conclusion The placental blood flow of FGR pregnant women will change significantly compared with that of healthy pregnant women. It is better to apply PI, RI and S/D values to the diagnosis and differentiation of FGR pregnant women. The placental pathology of FGR pregnant women will change significantly, and the PI, RI and S/D values will also change.
