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Table of Content

    16 July 2023, Volume 41 Issue 14
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    Effect of Speech and Hearing Feedback Nursing on Post-stroke Cognitive Impairment
    ZHANG Feng-xia
    2023, 41(14):  1-4. 
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    Objective To analyze the effect of speech and hearing feedback nursing on post-stroke cognitive impairment (PSCI). Methods A total of 82 elderly patients with PSCI admitted to Juancheng County People's Hospital from August 2020 to July 22 were selected as the study subjects, and were divided into control group and study group according to the random number table, with 41 cases in each group. The control group was given routine rehabilitation nursing, and the research group was given verbal and auditory feedback nursing on the basis of the control group. The scores of the Montreal Cognitive Assessment Scale (MoCA), the Simple Mental State Examination (MMSE), the markers of nerve injury [matrix metalloproteinase-9 (MMP-9), neuron-specific enolase (NSE)], the modified Barthel Index Scale (MBI) and nursing satisfaction were compared between the two groups. Results After 10 weeks of intervention, the scores of MoCA and MMSE in the study group were higher than those in the control group (P<0.05). After 10 weeks of intervention, the indexes of MMP-9 and NSE in the study group were lower than those in the control group (P<0.05). After 10 weeks of intervention, the score of MBI scale in the study group was higher than that in the control group (P<0.05). The total satisfaction rate of nursing service in the study group was higher than that in the control group (P<0.05). Conclusion Speech and hearing feedback nursing can effectively improve the cognitive function of elderly patients with PSCI, inhibit nerve injury, improve activities of daily living and nursing satisfaction, and is suitable for clinical promotion.
    Prediction of Preeclampsia in High-risk Pregnant Women by Aquaporin-1 and Interleukin-37 in the Second Trimester
    ZHANG Yi WANG Guo-hua
    2023, 41(14):  4-8. 
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    Objective To investigate the predictive value of aquaporin 1 (AQP1) and interleukin 37 (IL-37) in the second trimester of pregnancy on the occurrence of preeclampsia in high-risk pregnant women. Methods The 70 middle-pregnancy patients with high risk of predicting preeclampsia in early pregnancy admitted to Lianyungang First People's Hospital from January 2020 to December 2020 were selected as the study subjects. Among them, 22 pregnant women with preeclampsia were divided into the pre eclampsia group. Among them, 48 pregnant women without preeclampsia and with normal blood pressure were divided into the non preeclampsia group. In addition, 30 healthy non high risk pregnant women who came to our hospital for physical examination at the same time were selected as the control group to compare the AQP1 The expression level of IL-37 and the predictive value of AQP1 and IL-37 on the occurrence of preeclampsia in high-risk pregnant women were analyzed by using the ROC curve. All parturients were followed up and recorded postpartum neonatal status in 70 pregnant women with high risk of preeclampsia. Twenty newborns with Apgar score less than 7, amniotic fluid pollution degree of Ⅲ, and fetal heart rate of more than 180 beats/min were divided into the group with poor pregnancy outcome. The remaining 50 pregnant women were divided into the group with good pregnancy outcome. The general clinical characteristics of the two groups of parturients and the related clinical indicators in the second trimester of pregnancy were compared, and AQP1 The predictive value of IL-37 on adverse pregnancy outcome in preeclampsia. Results The expression levels of AQP1 and IL-37 in the third trimester of pregnancy were significantly different among the three groups. The expression levels of AQP1 and IL-37 in the pre-eclampsia group were significantly higher than those in the non-pre-eclampsia group and the control group (P<0.05); the predictive sensitivity and specificity of combination of AQP1 and IL-37 for preeclampsia were significantly higher than that of single prediction of AQP1 and IL-37, the predicted average threshold was calculated by predicting the highest and lowest thresholds, which were 14.58 μg/L for AQP1 and 234.62 pg/mL for IL-37; there was no significant difference in the age, body mass index, pregnancy times, birth times, family history of hypertension and history of hypertension before pregnancy between the poor pregnancy outcome group and the good pregnancy outcome group (P>0.05), but there were significant difference in the levels of DBP, SBP, urinary protein, AQP1 and IL-37 in the second trimester of pregnancy (P<0.05); the results of logistic regression analysis showed that urinary protein, AQP1 and IL-37 were independent influencing factors of adverse pregnancy outcome in high-risk pregnant women with preeclampsia (P<0.05). Conclusion The levels of AQP1 and IL-37 in the second trimester of pregnancy have important predictive value for pre eclampsia in high-risk pregnant women, and their predictive threshold values are respectively 14.58 μg/L, 234.62 pg/mL, and the combination of the two has higher prediction efficiency. At the same time, AQP1 and IL-37 in the second trimester can also predict the occurrence of adverse pregnancy outcomes in high-risk pre eclampsia pregnant women. Therefore, clinical intervention should be carried out for pregnant women with elevated levels of AQP1 and IL-37 in the second trimester to prevent adverse pregnancy outcomes.
    Effects of Breathing Rehabilitation Training on Middle-aged and Elderly Patients with Simple Obstructive Sleep Apnea: a Meta-analysis of Randomized Controlled Trials
    CAO Wei-hao, ZHANG Hui, LI Ting-ting, WANG Hong-ying, YUAN Zhi-qiong
    2023, 41(14):  8-13. 
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    Objective To evaluate the efficacy of respiratory rehabilitation training in the treatment of middle-aged and elderly patients with simple obstructive sleep apnea syndrome (OSAS). Methods The study has been registered on platform PROSPERO (No. CRD42022331424). Search PubMed, Embase, Web of science and Cochrane Library, China knowledge Network full-text Database, China Biomedical Literature Database, WANFANG, VIP to obtain randomized controlled trials of respiratory-related training in the treatment of OSAS. The search time limit is from the establishment of the database to April 2022. The quality is evaluated through the Cochrane system evaluation manual, the bias risk assessment chart is made by Revman5.4, and the data analysis software is based on Stata15.1 software. Results 7 literatures were obtained, with a total of 141 subjects. Meta analysis showed that after respiratory rehabilitation training, there was no significant difference in the score of sleep disturbance index(AHI) (MD=-0.13, 95% CI-0.52-0.26, P>0.05) between the test group and the control group, but the scores of Epworth sleepiness scale(MD=-0.79, 95% CI-1.22- -0.36,P<0.05) and PSQI sleep quality index (MD=-1.23, 95% CI -1.66- -0.79, P<0.05) in the test group were significantly better than those in the control group. Conclusion Breathing rehabilitation training can improve the clinical symptoms of OSAS, reduce daytime drowsiness and improve sleep quality.
    The Thickness of the Breast Capsular as an Indicator of the Severity of Capsular Contraction and its Correlation with Baker Grade
    PENG Hong-xia
    2023, 41(14):  13-16. 
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    Objective To explore the feasibility of breast ultrasound capsule thickness as an index to evaluate the severity of capsule contraction, and to analyze its correlation with Baker's grading of patients. Methods The 85 patients (170 breasts) eligible for the inclusion of Songyuan Central Hospital from July 2019 to January 2022 were included, the capsule thickness was measured by ultrasound and histological examination, analyzed the distribution of Baker grades Baker Ⅰ, Ⅱ, Ⅲ and Ⅳ, and the analysis of the correlation coefficient within 95% confidence interval. Results Among the 85 left breast implants, 43 were Baker Ⅰ, 11 Baker Ⅱ, 16 Baker Ⅲ, 15 Baker Ⅳ, 41 Baker Ⅰ, 13 Baker Ⅱ, 14 Baker Ⅲ, and 17 Baker Ⅳ According to the statistics, it included capsular spasm, prosthesis rupture, dislocation, implant-related anaplastic changes of breast implants, discomfort, foreign body sensation, size changes, but the capsular spasm accounted for the highest proportion, reaching 40.00%. The ultrasonic examination showed that the capsule thickness of Baker Ⅱ, Baker Ⅲ and Baker Ⅳ patients was (0.58 ± 0.11) mm, (1.07 ± 0.16) mm and (1.89 ± 0.55) mm, respectively, while the histological examination showed that the capsule thickness of Baker Ⅰ, Baker Ⅱ, Baker Ⅲ and Baker Ⅳ patients was (0.28 ± 0.07) mm, (0.58 ± 0.08) mm, (1.06 ± 0.14) mm and (2.13 ± 1.14) mm, respectively, The results showed that there was no significant difference in capsule thickness between the two detection methods and different Baker grades (P>0.05). Conclusion It is feasible to use breast ultrasound capsule thickness as an assessment of the severity of capsule contraction. There is a significant correlation between it and Baker grading, and there is no significant difference between it and histological capsule thickness detection. Therefore, this method can be considered for clinical application.
    Clinical Effect of Donepezil Hydrochloride Combined with Repetitive Transcranial Magnetic Stimulation on Patients with Alzheimer Disease
    GENG Jing
    2023, 41(14):  17-20. 
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    Objective To explore the clinical effect of donepezil hydrochloride combined with repetitive transcranial magnetic stimulation on patients with Alzheimer disease. Methods 96 patients with Alzheimer disease who were treated in Linyi Mental Health Center from January 2021 to October 2022 were selected as the subjects of this study. They were randomly divided into two groups with 48 patients each. The control group was treated with oral donepezil hydrochloride, and the experimental group was treated with repeated transcranial magnetic stimulation on the basis of the control group. The cognitive function, activities of daily living (ADL) and sleep quality of the two groups were observed before and after treatment. Results Mini-mental State Examination (MMSE) of the two groups before intervention was compared (P>0.05); after the intervention, the MMSE score of patients in the two groups was higher than that before the intervention, and the MMSE score in the experimental group was higher than that in the control group (P<0.05). ADL score and Pittsburgh Sleep Quality Index (PSQI) score between the two groups were compared before intervention, with no significant difference (P>0.05); after the intervention, the ADL score and PSQI score of the two groups were lower than those before the intervention, and the ADL score and PSQI score of the experimental group were lower than those of the control group (P<0.05). Conclusion The application of donepezil hydrochloride combined with repetitive transcranial magnetic stimulation in patients with Alzheimer disease can effectively improve the mental state, daily living ability and sleep quality of patients, which is worthy of clinical application.
    Effects of Video-assisted Thoracoscopic Anatomic Segmental Resection on Postoperative Lung Function and Inflammatory Response in Patients with Early Non-small Cell Lung Cancer
    LIU Xiang
    2023, 41(14):  20-24. 
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    Objective To investigate the effects of video-assisted thoracoscopic anatomic segmental resection on postoperative lung function and inflammatory response in patients with early non-small cell lung cancer (NSCLC). Methods A total of 92 patients with early stage NSCLC admitted to the Department of General Surgery of Lanling County People's Hospital from April 2020 to May 2022 were divided into two groups according to different surgical programs, with 46 patients in each group. The control group was treated with video-assisted thoracoscopic lobectomy, while the observation group was treated with video-assisted thoracoscopic anatomic segmental resection. Operation related indexes (operation time,number of lymph dissection, intraoperative blood loss, postoperative drainage time, postoperative drainage volume and postoperative hospital stay) were recorded in the two groups. The changes of lung function (forced vital capacity (FVC), maximum volume of air volume (MVV), forced expiratory volume in one second (FEV1)) and inflammatory response indicators [tumor necrosis factor-α (TNF-α), C-reactive protein (CRP) and interleukin-6 (IL-6)] before and after operation were compared between the two groups. The complication rate and recurrence rate of the two groups were investigated after 6 months of follow-up. Results Compared with the control group, the operation time of the observation group was extended, but the intraoperative blood loss, postoperative drainage volume, postoperative drainage time and hospital stay were reduced, the difference was statistically significant (P<0.05). There was no significant difference in the number of lymph dissection between the two groups (P>0.05). 30 days after surgery, the values of FVC, MVV and FEV1 in 2 groups were decreased compared with those before surgery, but the observation group was higher than the control group, the difference was statistically significant (P<0.05). At 3 days after operation, serum TNF-α, CRP and IL-6 in 2 groups were higher than those before operation, but the observation group was lower than the control group, the difference was statistically significant (P<0.05). After surgery, there was no significant difference in the total complication rate and recurrence rate within 6 months between the two groups (P>0.05). Conclusion Video-assisted thoracoscopic anatomic segmental resection in the treatment of early NSCLC has significant minimally invasive advantages, which can avoid serious damage to patients' lung function, improve inflammatory response, reduce the possibility of disease recurrence in the near term,facilitate rapid postoperative recovery of the body, and have high surgical safety, which can be applied in clinical application.
    Observation on the Therapeutic Effect of External Application of Jinhuang Powder in Treating Ankle Fracture
    JIANG Yong, JIANG Bo, DING Hui-Yong
    2023, 41(14):  24-27. 
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    Objective To observe the curative effect of external application of Jinhuang Powder on ankle fracture in the waiting period. Methods A total of 100 patients with ankle fracture to be treated in Gongshu District People's Hospital of Integrated Traditional Chinese and Western Medicine from August 2021 to December 2022 were selected. According to different treatment methods, 50 patients were included in the control group and 50 patients in the observation group. The control group was treated with routine treatment, and the observation group was treated with routine treatment and external application of Jinhuang powder. For the local skin temperature, the circumference of the affected ankle joint, the degree of swelling, the score of the degree of pain, the index of pain medium (substance P, 5-hydroxytryptamine, norepinephrine) Pain relief effect and inflammatory factor level (hypersensitive C-reactive protein, interleukin-6, tumor necrosis factor-α). Results The local skin temperature of the observation group on the 1st, 3rd, 5th and 7th day of treatment was lower than that of the control group (P<0.05); The circumference of the affected ankle in the observation group on the 1st, 3rd, 5th and 7th day of treatment was smaller than that in the control group (P<0.05); after treatment, the constituent ratio of mild swelling in the observation group was higher than that in the control group (P<0.05), and the constituent ratio of severe swelling was lower than that in the control group (P<0.05). There was no difference between the two groups in moderate swelling (P>0.05); the VAS score of the observation group after treatment was lower than that of the control group (P<0.05); the levels of substance P, 5-hydroxytryptamine and norepinephrine in the observation group after treatment were lower than those in the control group (P<0.05); the total effective rate of pain relief in the observation group was higher than that in the control group (P<0.05); the level of hypersensitivity C-reactive protein, interleukin-6, tumor necrosis factor in the observation group after treatment-α was lower than that of the control group (P<0.05). Conclusion The external application of Jinhuangsan has a significant effect on the treatment of ankle fracture to be operated. It can stabilize the skin temperature of the affected area, reduce the circumference of the affected ankle joint, reduce the degree of swelling and pain, and improve the indicators of pain mediators and reduce the level of inflammatory factors to a certain extent. The pain relief effect is good, which can be popularized and applied.
    Effect of Xiao'er Feire Kechuan Granules Combined with Budesonide on Children with Bronchial Pneumonia
    YANG Xian-hua, LU Cai-xia
    2023, 41(14):  28-31. 
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    Objective To investigate the effect of Xiao'er Feire Kechuan Granules Combined with Budesonide on Children with Bronchial Pneumonia. Methods 86 cases of patients with bronchial pneumonia admitted to Xinjiang Changji Prefecture Hospital of TCM from January 2021 to December 2022 were selected, and were divided into two groups randomly. The control group was treated with budesonide alone, and the observation group was pediatric pulmonary hot cough and asthma particles combined with budesonide. Indices related to clinial manifestation, blood gas indices [SpO2, PaO2, FiO2, PaCO2], lung function indices [VPTEF/VE, RR, TPTEF/TE and VT] and serum indexes [pulmonary surfactant protein D (SP-D), soluble interleukin-2 receptor (sIL-2R), interferon- γ (INF- γ), insulin like growth factor (IGF-Ⅱ)] were detected and compared. Results The effective rate of the observation group was significantly higher than that of the control group (P<0.05). The disappearance time of cough, fever, wheezing and lung rale in the observation group were shorter (P<0.05). After treatment, the SpO2, PaO2, OI and PaCO2 in the two groups were significantly improved (P<0.05), and the observation group were significantly better than those in the control group (P<0.05). After treatment, VPTEF/VE, RR, TPTEF/TE and VT in the two groups were significantly improved (P<0.05), and the observation group were significantly better than those in the control group (P<0.05). After treatment, serum SP-D, sIL-2R, INF-γAnd IGF-Ⅱ levels were significantly improved (P<0.05), and the control group were significantly higher than those in the control group (P<0.05). Conclusion Xiao'er Feire Kechuan Granules combined with budesonide has a significant effect on children with bronchopneumonia, which is worth promoting.
    Clinical Study of Balanced Needle Knife Therapy in the Treatment of Cervicogenic Headache
    ZHANG Yong
    2023, 41(14):  31-34. 
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    Objective To observe the clinical efficacy of balance acupotomology and acupuncture combined with electroacupuncture in the treatment of cervical headache. Methods A total of 60 patients admitted to the Department of Rehabilitation Medicine in Zhangqiu District Hospital of Traditional Chinese Medicine of Jinan City from June 2020 to June 2022 were selected as research objects and divided into observation group and control group according to random drawing method, with 30 patients in each group. Thirty patients in the observation group were given balance acupotomy therapy, and 30 patients in the control group were given acupuncture and electroacupuncture therapy. The clinical efficacy before and after treatment was compared, and the therapeutic effect was evaluated. Results The visual analogue scale (VAS) score of patients with various types of pain in the observation group was significantly lower than that of patients with various types of pain in the control group treated with acupuncture and moxibustion and electroacupuncture (P<0.05). The total effective rate of balanced acupotomy in the observation group was higher than that of acupuncture and moxibustion plus electroacupuncture in the control group (P<0.05). Conclusion Acupuncture and moxibustion plus electroacupuncture and balanced acupotomy can effectively alleviate cervicogenic headache. acupuncture and moxibustion plus electroacupuncture is simple and convenient, Balanced needle knife therapy is economical, efficient and not easy to repeat for patients with cervicogenic headache.The balanced acupotomy improved the headache symptoms of patients with cervicogenic headache more significantly, with a high effective rate.
    Advantages of a Modified Four-lumen Urinary Catheter in Bladder Irrigation: a Prospective Randomized Controlled Study
    XING Jun-lian, LI Yang, LIU Jia, LIU Ling, WANG Rui, XU Ping, LIU Fang, RONG Xiao-yan, CHENG Xiao-yu, HUANG Ling, TANG Liang-you, CHEN Yong-bo
    2023, 41(14):  38-41. 
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    Objective To explore the clinical value of modified catheter in bladder irrigation. Methods From February 2021 to January 2022, 64 patients with bladder tamponade and bladder irrigation who were hospitalized in the department of urology in a tertiary hospital in Deyang City were randomly divided into control group（33 cases） and experimental group（31 cases）. The control group was placed with a common three-chamber catheter, and the test group was placed with a modified catheter. The differences between the two groups were compared in terms of length of hospital stay, manual washing time, bladder washing time, indwelling catheter time, the number of bladder spasms, the number of urinary tract infections, comfort, and the satisfaction of patients and nurses. Results Compared with the control group, the number of hospitalization, manual washing time (points), bladder washing time (days), and time (days) were significantly lower than the control group (P <0.05). The number of bladder spasm during indwelling catheter was significantly lower (P<0.05). The prevalence of urinary tract infection and urine bacteria after irrigation and urine culture was significantly better than the control group (P<0.05). The overall comfort, patient satisfaction and satisfaction with nurses were significantly increased (P<0.05). Conclusion Compared with the common three-chamber catheter, the modified catheter can shorten the total hospitalization time of patients, reduce the manual washing time of nurses, reduce the bladder washing time, shorten the days of indwelling catheter, reduce the frequency of bladder spasm, reduce urinary tract infection, increase the comfort of patients, and improve the satisfaction of patients and nurses. It has important clinical significance and is worth promoting.
    Clinical Study of Coaxial Microincision Phacoemulsification Combined with Trabeculectomy in Patients with Primary Angle-Closure Glaucoma Complicated with Cataract
    SUN Ai-guo
    2023, 41(14):  55-58. 
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    Objective To analyze the effect of coaxial microincision (1.8 mm) phacoemulsification combined with trabeculectomy in patients with primary angle-closure glaucoma (PACG) and cataracts. Methods The medical records of 80 patients with PACG and cataract admitted to our hospital from April 2020 to April 2021 were retrospectively analyzed, and they were divided into two groups by different treatment measures. Among them, 40 patients who underwent phacoemulsification simple trabeculectomy were included in the control group, and 40 patients who underwent coaxial microincision (1.8 mm) phacoemulsification combined with trabeculectomy were included in the observation group until 3 months after surgery. The two groups were compared with intraocular pressure, central anterior chamber depth, visual acuity improvement, quality of life, and complications. Results Before surgery, there were no significant differences between intraocular pressure, central anterior chamber depth, BCVA and the scores of each dimension in GQOLI-74 (P>0.05); after surgery, the observation group's depth of central anterior chamber, BCVA and the scores of each dimension in GQOLI-74 were higher than control group's (P<0.05); but the comparison of two groups in intraocular pressure was no significant difference(P>0.05); the observation group's complication rate was lower than control group's (P<0.05). Conclusion Coaxial microincision phacoemulsification + trabeculectomy has obvious effect in the treatment of patients with PACG combined with cataracts, which can significantly control eye pressure, regulate vision, improve quality of life, and have fewer complications, high clinical application value, and worthy of vigorous application.
    Analysis of Anesthesia Effect of TAP and INB on Patients Undergoing Laparoscopic Hernia Repair
    LIU Yi-jun
    2023, 41(14):  61-65. 
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    Objective To investigate the effect of general anesthesia combined with transversus abdominis plane block (TAP) and Inferior iliac and inguinal nerve block (INB) on patients undergoing laparoscopic hernia repair. Methods From June 2021 to May 2022, 80 patients with laparoscopic hernia repair who were treated in Jingjiang Hospital of Traditional Chinese Medicine were prospectively selected as the research objects, and they were divided into the study group (n=40) and the control group by random number table method (n=40). The control group was given TAP, and the study group was given INB anesthesia. To compare the efficacy of the two groups, the physical signs [blood pressure (MAP), heart rate (HR), blood oxygen saturation (SpO2)], adverse reactions and anesthesia indicators (wake time, pain score after anesthesia, amount of fentanyl, time of directional force recovery). Results The anesthesia rate of anesthesia in the study group was higher than that in the control group (P<0.05). There was no difference in MAP, HR, and SpO2 sign indicators between the two groups (P>0.05), MAP and HR decreased 2 min after nerve block in the two groups, and the study group were lower than the control group (P<0.05), and no significant difference between SpO2 indicators (P>0.05). After comparison, the incidence of adverse reactions in the study group was significantly lower than that in the control group group (P<0.05). The recovery time, post-anesthesia analgesia score, fentanyl dosage, and directional force recovery time were all shorter or less than that of the control group (P<0.05). Conclusion Ilioinguinal nerve block can be used in laparoscopic hernia repair. The anesthesia effect is stable, the patient's physique index is stable, and the incidence of side effects is small, which is worthy of application.
    The Application Effect of Qingfei Kuanxiong Liqi Decoction Combined with Budesonide in Patients with Chronic Obstructive Pulmonary Disease Complicated with Respiratory Failure
    LI Shu-gang, HU Jun-bo, LIU Yuan-yuan, YU Tao, TIAN Xiao-dong
    2023, 41(14):  71-75. 
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    Objective To investigate the effect of Qingfei Kuanxiong Liqi Decoction combined with budesonide on chronic obstructive pulmonary disease (COPD) patients with respiratory failure and its influence on pulmonary function. Methods A total of 96 patients with COPD failure admitted to Dunhuang City Hospital from May 2020 to July 2022 were divided into two groups. The control group was treated with budesonide nebulization inhalation in addition to conventional treatment,the experimental group was treated with Qingfei Kuanxiong Liqi Decoction in addition to the control group,and the two groups were observed for 14 d. Record the blood gas analysis indicators, improvement of lung function, and clinical efficacy before and after treatment in both groups. Results After treatment, FEV1, FEV1 / FVC and PEF of the two groups were significantly higher, and the difference was statistically significant (P<0.05),while the improvement in the experimental group was significantly higher than that of the control group, and the difference was statistically significant (P<0.05). After treatment, the levels of PaO2, SpO2, pH, PaO2 / FiO2 were significantly increased, and the PaCO2 level was reduced, and the difference was statistically significant (P<0.05), while in the experimental group, PaO2, SpO2, pH, PaO2/FiO2 levels were significantly higher than the control group, and the PaCO2 level was lower than the control group, the difference was statistically significant (P<0.05). There was no statistically significant difference in the total effective rate between the two groups of patients (P>0.05). The number of acute exacerbations in the experimental group was significantly less than that in the control group (P<0.05). Conclusion Compared with budesonide alone, Qingfei Kuanxiong Liqi Decoction is helpful to improve lung function and blood gas analysis, and reduce the risk of acute attack.
    Study on the Relationship Between the Incidence of Cerebral Infarction and Meteorological Factors in Tianjin Based on Meteorological Data
    XIE Ping-an, LIU Pei-lin, JIAO Yang, WANG Lin, LI Xin
    2023, 41(14):  78-81. 
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    Objective To explore the relationship between cerebral infarction and meteorological factors in Tianjin. Methods A total of 15 401 hospitalized cases diagnosed with cerebral infarction in the First Affiliated Hospital of Tianjin University of Chinese Medicine from January 2019 to Decmber 2020 were retrospectively collected, and collected with concurrent meteorological data in Tianjin. At the nodes of the 24 solar terms, patients were grouped according to the admission time, the distribution of cerebral infarction in the 24 solar terms was analyzed, and the correlation between the high incidence period of cerebral infarction in the 24 solar terms and meteorological factors was analyzed. To explore the relationship between meteorological changes and cerebral infarction admission. Results Spring admission peak period (Rain Water-Lesser Fullness of Grain), admission stable period (Grain in Ear-the Autumn Equinox), autumn-admission peak period (Cold Dew-the Beginning of Winter), decreasing period of admissions (Lesser Snow-the Beginning of Spring). The results of the univariate analysis showed that the poor daily average air temperature and the daily air temperature had an influence on the admission of cerebral infarction, due to the correlation among the various meteorological factors. Conclusion Rain Water-Lesser Fullness of Grain, Cold Dew-the Beginning of Winter is the peak of cerebral infarction admission, Lesser Snow-the Beginning of Spring is the trough of cerebral infarction admission, and the number of admissions in Grain in Ear-the Autumn Equinox is relatively balanced. Temperature Poor temperature and daily average temperature are the main meteorological factors of cerebral infarction admission, and the male population is more sensitive.
    Correlation between Cardiac Troponin, Brain Natriuretic Peptide and Severity of Acute Myocardial Infarction Complicated with Heart Failure and Prognosis Prediction
    WU Yao-qing WU Mu-fu FENG Yan-feng
    2023, 41(14):  177-181. 
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    Objective To investigate the correlation between cardiac troponin （cTnT）, brain natriuretic peptide （BNP） and the severity of acute myocardial infarction （AMI） complicated with heart failure, and to predict the prognosis. Methods A total of 100 patients with acute myocardial infarction complicated with heart failure admitted to our hospital from January 2022 to December 2022 were selected as the study objects. All patients were divided into 16 patients of grade I, 23 patients of grade II, 34 patients of grade III, and 27 patients of grade IV. 50 healthy volunteers who came to our hospital for physical examination at the same time were selected as the control group. The expression levels of cTnT and BNP in five groups of patients were compared, and cTnT, BNP were analyzed The correlation between BNP and the severity of acute myocardial infarction complicated with heart failure. Then 100 patients with acute myocardial infarction complicated by heart failure were divided into death group （n=32） and survival group （n=68）. The general clinical conditions of the two groups were compared, and the prognostic value of cTnT and BNP for the prognosis of acute myocardial infarction complicated by heart failure was analyzed. Results The levels of cTnT and BNP in the five groups were significantly higher than those in the three groups （P<0.05）; Spearman correlation analysis showed that cTnT and BNP were positively correlated with the severity of acute myocardial infarction complicated with heart failure （P<0.05）; There was no significant difference in sex, age, BMI, diabetes, hypertension, hyperlipidemia, left ventricular ejection fraction, number of stents, and length of stents between the survival group and the death group （P>0.05）. There was significant difference in Killip grade, old myocardial infarction, cTnT, and BNP levels between the survival group and the death group （P<0.05）; The above indexes with statistical difference in univariate analysis were assigned. The results of logistic regression analysis showed that cTnT and BNP were independent predictors of the prognosis of acute myocardial infarction complicated with heart failure （P<0.05）. Conclusion Cardiac troponin and brain natriuretic peptide have obvious relationship with the severity of acute myocardial infarction complicated with heart failure, and can predict the prognosis of patients with acute myocardial infarction complicated with heart failure by cTnT and BNP reaction levels. In order to further reduce the mortality of patients with acute myocardial infarction （AMI） complicated by heart failure （HF） with elevated cTnT and BNP, we can consider adjusting the treatment plan in time.