Table of Content

16 May 2022, Volume 40 Issue 10

Previous Issue    Next Issue

Effects of Ingrown Toenail Correction Nursing Technique on Preventing Diabetic Foot

HE Shu-min, YI Cai-lan, LIANG Cai-yi, LUO Qin, ZHOU Xiao-zhou

2022, 40(10):  1-4. 

Asbtract ( 219 )   PDF (1997KB) ( 42 )  

References | Related Articles | Metrics

Objective To reveal the effects of ingrown toenail correction nursing technique on preventing diabetic foot in diabetic patients. Methods One hundred and four diabetic patients with ingrown toenail in The First Hospital Affiliated to Guangzhou Pharmaceutical University from January 2019 to January 2021 were investigated herein. These patients were randomly divided in to control group and observation group with 52 patients in each one. The control group was treated with routine trimming while the observation group was subject to ingrown toenail correction nursing technique. And patient recovery, pain and strain before or after trimming nails, total effective rate and incidence of diabetic foot were assessed. Results Incontrast to control group, wound drying time and wound healing time of the patients in observation group were obviously shortened (P<0.05). The times of dressing changed in observation group were fewer than control group (P<0.05). The grades of resting compression, walking compression, resting pain and walking pain for patients in observation group were lower than control group remarkably (P<0.05). The total effective rate of the observation group was significantly higher than that of the control group (P<0.05). The incidence of diabetic foot in the observation group was significantly lower than that in the control group (P<0.05). Conclusion Ingrown toenail correction nursing technique could take effective measures to attenuate diabetic patients with ingrown toenail against diabetic foot, accelerate the recovery of patients with ingrown toenail, ameliorate foot pain and compression of patients, and improve the prognosis of patients.

Application of Dexmedetomidine Combined with Ropivacaine in Colorectal Cancer Surgery

LI Shen-zhan

2022, 40(10):  4-7. 

Asbtract ( 122 )   PDF (1995KB) ( 26 )  

References | Related Articles | Metrics

Objective To investigate the value of dexmedetomidine combined with ropivacaine in transversus abdominis plane(TAP) block in patients undergoing colorectal cancer surgery. Methods A total of 72 patients with colorectal cancer undergoing general anesthesia in Jinxiang County People’s Hospital from January 2019 to December 2021 were selected as the research subjects, and were randomly divided into control group (36 cases) and observation group (36 cases). Both groups were treated with TAP block after anesthesia induction. The control group was treated with ropivacaine and the observation group was treated with dexmedetomidine combined with ropivacaine. The analgesic effect [visual analogue scale (VAS) score], postoperative recovery, stress response [serum cortisol (Cor), epinephrine (E)], inflammatory factor [tumor necrosis factor α (TNF-α), interleukin-6 (IL-6)] and adverse symptoms were compared between the two groups. Results The VAS scores of the observation group were lower than those of the control group at 6 h, 8 h, 12 h and 24 h after operation, and the anesthesia, exhaustion, defecation, out-of-bed activity and hospitalization time were shorter than those of the control group, the difference was statistically significant. (P<0.05); Before anesthesia, there was no statistically significant difference in Cor, E, TNF-α and IL-6 between the two groups (P>0.05); 24 hours after operation, Cor, E, TNF-α and IL-6 in the observation group were lower than those in the control group, the difference was statistically significant. (P<0.05); The adverse reactions of the two groups were similar, and there was no statistically significant difference (P>0.05). Conclusion Dexmedetomidine combined with ropivacaine for TAP block in patients with colorectal cancer surgery can obtain good analgesic effect, and alleviate the body stress reaction and inflammatory reaction, which may lay a good foundation for postoperative recovery, and high safety, worthy of clinical application.

Accuracy Analysis of CT and MRI Diagnosis of Common Adrenal Tumors

LI Zhong-min

2022, 40(10):  7-10. 

Asbtract ( 1271 )   PDF (1994KB) ( 45 )  

References | Related Articles | Metrics

Objective To study the diagnostic accuracy of CT and MRI in common adrenal tumors. Methods From January 2018 to December 2020, 60 patients suspected of adrenal tumors were studied in Dongming County Hospital of Traditional Chinese Medicine. CT and MRI were performed, and the diagnosis results of the two methods were compared with the results of surgical and pathological examination as the gold standard. Results A total of 58 patients were diagnosed as adrenal tumors, 45 as benign tumors and 13 as malignant tumors. The detection rate and coincidence rate of MRI were higher than that of CT, the difference was statistically significant (P<0.05). The accuracy of localization diagnosis of benign and malignant adrenal tumors by CT was higher than that by MRI, and the accuracy of qualitative diagnosis of benign adrenal tumors by MRI was higher than that by CT, the difference was statistically significant (P<0.05); The specificity and accuracy of MRI were higher than that of CT, the difference was statistically significant (P<0.05). Conclusion Compared with CT examination, MRI examination has a higher detection rate of pathological types of adrenal tumors. In the localization and qualitative diagnosis of benign and malignant adrenal tumors, CT examination and MRI examination have their own advantages and disadvantages. In clinical practice, we should choose the examination methods reasonably, or combine the two examination methods, and then make qualitative diagnosis by MRI after CT localization diagnosis, so as to improve the diagnostic accuracy.

Effect of Targeted Nursing Intervention on Patients with Diabetes Mellitus Complicated with Fundus Hemorrhage

XU Xia, WANG Ting-gang

2022, 40(10):  11-14. 

Asbtract ( 108 )   PDF (1996KB) ( 84 )  

References | Related Articles | Metrics

Objective To explore the effect of targeted nursing intervention on improving vision in diabetic patients with fundus hemorrhage. Methods From January 2020 to December 2020, 100 patients with diabetes and fundus hemorrhage treated in the Lanling County People’s Hospital were selected and divided into observation group and control group according to coin tossing results, 50 cases in each group. The control group implemented routine nursing intervention, and the observation group carried out targeted nursing intervention. The blood glucose index, macular thickness, visual acuity results and quality of life of the two groups were compared before and after nursing, and the nursing satisfaction of the two groups was compared. Results After nursing intervention, the blood glucose index of patients in the observation group was lower than that in the control group, and the difference was statistically significant (P<0.05). The macular thickness of patients in the observation group was lower than that in the control group, and the scores of visual acuity and quality of life in the observation group were higher than those in the control group, and the difference was statistically significant (P<0.05). Conclusion Diabetic patients with ocular fundus bleeding can effectively promote the recovery of vision through targeted nursing, which is worthy of clinical application.

Effect of Anesthesia Awakening Nursing on Improving Postoperative Quality of Life of Patients Undergoing Thoracoscopic Radical Lung Cancer Surgery

YUAN Ping

2022, 40(10):  14-17. 

Asbtract ( 132 )   PDF (1992KB) ( 38 )  

References | Related Articles | Metrics

Objective To explore the effect of anesthesia awakening nursing on improving the quality of life of patients undergoing thoracoscopic radical resection of lung cancer. Methods Eighty patients with lung cancer admitted to the Department of Anesthesia and Perioperative Medicine of Shandong Public Health Clinical Center from January 2019 to January 2020 were treated with thoracoscopic radical lung cancer surgery. They were divided into control group and observation group by touching the ball with 40 cases in each one.The control group was adopted routine video-assisted thoracoscopic nursing intervention mode, and the observation group was adopted the anesthesia awakening nursing intervention mode. The indexes of postoperative recovery (anal exhaust time, catheter indwelling time, thoracic tube indwelling time, consciousness recovery time, tracheal tube removal time, hospitalization time), pain visual analogue scale (VAS), complication rate, blood pressure and heart rate, quality of life, nursing satisfaction were compared between the two groups. Results The postoperative anal exhaust time, indwelling time of urinary catheter and indwelling time of thoracic tube in the observation group were less than those in the control group, and the difference was statistically significant (P<0.05); the pain scores of patients in the observation group at 6 h, 12 h, 24 h and 48 h after operation were lower than those in the control group, and the difference was statistically significant (P<0.05); the incidence of postoperative complications in the observation group was lower than that in the control group (P<0.05); the blood pressure and heart rate in the observation group were significantly lower than those in the control group (P<0.05); the scores of quality of life in the observation group were higher than those in the control group (P<0.05); the nursing satisfaction of the observation group was higher than that of the control group, and the difference was statistically significant (P<0.05). Conclusion Nursing intervention of anesthesia after thoracoscopic radical resection of lung cancer can speed up the postoperative recovery process, reduce the degree of pain and complication rate, and help stabilize vital signs and improve the quality of life.

The Study of Efficacy of Chemotherapy Combined with Targeted Drug Therapy in Patients with Advanced Non-small Cell Lung Cancer

XIN Hong-mei, BAO Yong-jian

2022, 40(10):  18-20. 

Asbtract ( 144 )   PDF (1980KB) ( 35 )  

References | Related Articles | Metrics

Objective To study the efficacy of chemotherapy combined with targeted drug therapy in patients with advanced non-small cell lung cancer （NSCLC）. Methods A total of 80 patients with NSCLC who were admitted and treated in Sinopharm North Hospital from October 2019 to October 2020 were selected. They were randomly divided into two groups, the observation group and the control group.The control group received chemotherapy, while the observation group received chemotherapy combined with targeted drug therapy. The the prognosis of NSCLC patients in the two groups were compared, including treatment effect and adverse reactions, quality of life and lung function. Results The European Organization for Research and Treatment of Cancer （EORTC QLQ-C30） score in the observation group was significantly higher than that in the control group （P<0.05）. The forced vital capacity （FVC） and forced expiratory volume in one second （FEV₁） of patients in the observation group were significantly higher than those in the control group （P<0.05）. The total effective rate in the observation group was significantly higher than that in the control group （P<0.05）; the incidences of adverse reactions such as nausea, vomiting, rash, diarrhea, and bone marrow suppression in the observation group were significantly less than those in the observation group were significantly lower than those in the control group （P<0.05）. Conclusion Chemotherapy combined with targeted drugscould improve the clinical efficacy and lung function of NSCLC patients, while improving the quality of life of patients, with high safety.

Application of Serum Glycoprotein Sugar Chain in Early Diagnosis of Lung Cancer

XIE Jun, LIU Dan, TAN Xiao-wu, LUO Chun, DENG Xiao-jie, YI Man, DAI Bei, LIU Zhen-xue, LUO Qian

2022, 40(10):  21-26. 

Asbtract ( 123 )   PDF (2740KB) ( 43 )  

References | Related Articles | Metrics

Objective Through lectin microarray, the differences of serum glycoprotein sugar chain spectrum between patients with stages I, II, III and IV lung cancer and healthy volunteers were analyzed, and the sugar chain structure markers related to the occurrence and development of lung cancer were found, so as to provide clinical basis for earlier discovery and identification of lung cancer. Methods Lectin microarray was performed to analyze the glycoprotein expression profiles of serum samples from 54 patients with different stages of lung cancer （9 patients at stages I and II, 24 patients at stage III and 21 patients at stage IV） and 48 healthy volunteers in the Second Hospital Affiliated to South China University from September 2017 to October 2018. Hierarchical cluster analysis （HCA） and ratio value analysis were used to analyze the glycoprotein glycochain profiles of serum from patients with lung cancer and healthy volunteers. The results of lectin microarray were verified by lectin imprinting technique reversely. The ROC curve was used to preliminarily evaluate the potential value to apply the screened sugar chain structure identified by the differential lectin in the early diagnosis of lung cancer. Results The relative abundance of β-Gal and Galβ-1, 4GlcNAc sugar chain structures identified by RCA120 in all lung cancer patients was significantly lower than that in healthy volunteers. ROC curve showed that RCA120 could distinguishpatients with early lung cancer from healthy volunteersat AUC = 0.802, P = 0.004, which indicated that in serum β-Gal and Galβ-1, 4GlcNAc sugar chain structuresrecognized the lectin RCA120 could effectively distinguish patients with early lung cancer from healthy volunteers.Conclusion β-Gal and Galβ-1, 4GlcNAc sugar chain structures recognized by lectin RCA120 may contribute to the early diagnosis of lung cancer.