Table of Content

16 April 2022, Volume 40 Issue 8

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The Application Value of the Concept of Enhanced Recovery after Surgery in the Perioperative Period of Acute Cholecystitis

ZHONG Bo, WANG Hai, RONG Wan-shui, ZHAO Xiao-li, ZHU Zhen-zhong

2022, 40(8):  1-4. 

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Objective To explore the clinical efficacy of the concept of enhanced recovery after surgery in the treatment of acute cholecystitis, and to analyze the effects of postoperative gastrointestinal function recovery, postoperative pain and the body's stress state. Methods A total of 100 patients with acute cholecystitis from June 2018 to June 2021 admitted to Peking University Shougang Hospital were selected for study, and were randomly divided into the observation group and the control group, with 50 cases in each group. The control group was given routine surgical management during the perioperative period, and the observation group was given enhanced recovery surgery concept management. The postoperative gastrointestinal function recovery and complications were compared. The pain visual analogue scale was used to evaluate the pain status of patients after 6 h, 12 h and 24 h operation, and levels of IL-1β and tumor necrosis factor were detected by enzyme-linked immunosorbent assay after 6 h and 24 h operation. Results The postoperative bowel sounds recovery time, defecation time, anal exhaust time, ground activity time and hospital stay in the observation group were significant shorter than those in the control group (P<; 0.05). The incidence of postoperative complications in the observation group was significant lower than that in the control group (P<; 0.05). With the prolongation of time, the pain visual analog scores in the two groups gradually decreased, and the pain visual analog scores in the observation group were lower than those in the control group after 6 h, 12 h and 24 h operation, respectively. The levels of interleukin-1β and tumor necrosis factor in the two groups after 24 h operation were lower than those after 6 h. There was no significant difference in the levels of interleukin-1β and tumor necrosis factor between the two groups after 6 h operation. Moreover, the levels of interleukin-1β and tumor necrosis factor in the observation group were lower than those in the control group after 24 h operation. Conclusion The concept of enhanced recovery after surgery could promote the earlier recovery of postoperative gastrointestinal function in patients with acute cholecystitis, and reduce the degree and duration of postoperative pain, the risk of complications and the degree of stress response of the body, which is worthy of clinical application.;

Analysis of the Therapeutic Effect of Levocetirizine, Montelukast combined with BCG on Chronic Urticaria

LIU Guo-fang, ZHANG Zhi-jie

2022, 40(8):  4-6. 

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Objective To study the the therapeutic effect of levocetirizine, montelukast combined with BCG Bacillus Calmette-Guerin on chronic urticaria patients. Methods A total of 78 patients with chronic urticaria admitted to Feicheng Hospital Affiliated to Shandong First Medical University from February 2019 to November 2020 were selected. They were included and randomly divided into the observation group and the control group. Among them, 39 patients in the observation group received the therapy proctocol of levocetirizine, montelukast combined with BCG, while 39 patients in the control group received Bacillus Calmette-Guerin combined with montelukast. Quality of life score, treatment efficacy and clinical symptom subsidence time were administated between two groups. Results After treatment, the clinical symptom subsidence time in the observation group was significantly shorter than that in the control group (P<0.05). After treatment, the total efficiency of the observation group was significantly higher than that of the control group (P<0.05). After treatment, the quality of life score of the observation group was significantly higher than that of the control group (P<0.05). Conclusion The therapy protocol of levocetirizine, montelukast combined with BCG in chronic urticaria could significatly improve the clinical symptom subsidence time, improve the therapeutic effect and increase the quality of life score.

The Role of Ultrasound-guided Fine Needle Aspiration Cytology (FNAC) in the Diagnosis of Thyroid Cancer

LU Jing

2022, 40(8):  7-10. 

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Objective To analyze the value of ultrasound-guided fine needle aspiration cytology (FNAC) in the diagnosis of thyroid cancer. Methods A total of 67 patients with thyroid nodules (75 nodules) received treatment in Rizhao Central Hospital from November 2019 to November 2021 were selected for ultrasound-guided FNAC diagnosis, and pathological tissue biopsy results were used as the gold standard to record the diagnosis results and related analysis. Results The success rate of nodule puncture in the study subjects was 100.00%. The ultrasound-guided FNAC diagnosis results showed that malignant, suspiciously malignant, uncertain and benign accounted for 28.36%, 34.33%, 22.39% and 14.92% respectively Under the diagnosis of ultrasound-guided FNAC, one case was false negative, the negative predictive value was 88.00%,3 cases were false positive, and the positive predictive value was 97.62%. The diagnostic accuracy, sensitivity and specificity were 94.03%, 93.18% and 95.65% respectively. Conclusion In the diagnosis of thyroid cancer, the use of ultrasound-guided FNAC diagnosis has the characteristics of high accuracy, high sensitivity, high specificity and can be applied.

The Effect of Minimally Invasive Neurosurgery Technology Combined with Neurophysiological Monitoring in the Treatment of Brainstem Cavernous Hemangioma

SU Ying, HUI Zhi-qiang, HUANG Jian, FU Tao, XU Peng

2022, 40(8):  10-13. 

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Objective To analyze the curative effect of minimally invasive neurosurgery technique combined with neurophysiological monitoring on brainstem cavernous hemangioma. Methods 30 patients with brainstem cavernous hemangioma admitted to Linyi Central Hospital from January 2018 to January 2021 were selected and divided into control group (traditional brain microsurgery) and experimental group (minimally invasive neurosurgery technique + neurosurgery Electrophysiological monitoring) according to the random number table method, 15 patients in each group. The clinical efficacy, operation time, hospitalization time, the activities of daily living and functional status, the functional status of body and the Glasgow Outcome Scale (GOS) of the two groups were compared. Results The total effective rate of treatment in the experimental group was significantly higher than that in the control group (P<0.05). The operation time and hospital stay in the experimental group were significantly shorter than those in the control group (P<0.05). The postoperative activities of daily living (ADL) in the experimental group were significantly shorter. The scores and functional status (KPS) scores were significantly higher than those in the control group (P<0.05). The postoperative GOS scores in the control group accounted for 40.00% of the scores from 1 to 3, 60.00% from 4 to 5, and 6.67% and 93.33% in the experimental group respectively, and there was a significant difference between the two groups (P<0.05). Conclusion Micro-invasive neurosurgery technology combined with nerve electrophysiology monitoring brainstem cavernous hemangioma has a significant curative effect, can effectively promote the recovery of the patient's body, improve the ability of daily activities and functional status, and has a significant effect on improving the quality of life and sleep quality,with high safety and significantly clinical reference.

A Comparative Study of Clinical Efficacy between Laparoscopic Rectal Cancer Surgery and Traditional Open Rectal Cancer Surgery

WANG Hai-bo

2022, 40(8):  13-16. 

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Objective To explore the clinical efficacy of laparoscopic rectal cancer surgery and traditional open rectal cancer surgery. Methods A total of 50 patients with rectal cancer admitted to Chifeng City Hospital from January 2019 to January 2020 were selected as the research objects, and randomly divided into a control group and a research group, with 25 cases in each group. The control group was underwent traditional open radical surgery, while the research group was underwent laparoscopic radical surgery. The surgical indicators, such as pain degree, quality of life, gastrointestinal function and incidence of adverse reactions were compared between the two groups. Results The surgical indicators in the research group, such as incision length, intraoperative blood loss, bowel sound recovery time, anal defecation time and hospitalization time, were significant lower than those in the control group （P<0.05）. The pain scores of the patients in the research group at 1 d, 3 d, and 5 d after operation were significant lower than those in the control group （P<0.05）. The scores of quality life for the patients in the research group were significant higher than those in the control group （P<0.05）. The improvement of gastric function indexes in the research group was significant better than that in the control group （P<0.05）. The incidence of adverse reactions in the research group was significant lower than that in the control group （P<0.05）. Conclusion sThe curative effect of laparoscopic radical resection for rectal cancer patients is outstanding, which is helpful for the rapid recovery of gastrointestinal function, reduces adverse reactions, and improves the quality of life of patients. Collectively, the operation is safe and worthy of clinical application.