Abstract: Objective To analyze the value of ultrasound-guided fine needle aspiration cytology (FNAC) in the diagnosis of thyroid cancer. Methods A total of 67 patients with thyroid nodules (75 nodules) received treatment in Rizhao Central Hospital from November 2019 to November 2021 were selected for ultrasound-guided FNAC diagnosis, and pathological tissue biopsy results were used as the gold standard to record the diagnosis results and related analysis. Results The success rate of nodule puncture in the study subjects was 100.00%. The ultrasound-guided FNAC diagnosis results showed that malignant, suspiciously malignant, uncertain and benign accounted for 28.36%, 34.33%, 22.39% and 14.92% respectively Under the diagnosis of ultrasound-guided FNAC, one case was false negative, the negative predictive value was 88.00%,3 cases were false positive, and the positive predictive value was 97.62%. The diagnostic accuracy, sensitivity and specificity were 94.03%, 93.18% and 95.65% respectively. Conclusion In the diagnosis of thyroid cancer, the use of ultrasound-guided FNAC diagnosis has the characteristics of high accuracy, high sensitivity, high specificity and can be applied.

Key words: thyroid cancer, ultrasound guidance, FNAC, diagnosis results