ZHONGHUA YANGSHENG BAOJIAN ›› 2022, Vol. 40 ›› Issue (8): 4-6.

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Analysis of the Therapeutic Effect of Levocetirizine, Montelukast combined with BCG on Chronic Urticaria

LIU Guo-fang1, ZHANG Zhi-jie2   

  1. 1. Department of Dermatology and Venereology, Feicheng Hospital Affiliated to Shandong First Medical University,Tai'an Shandong 271600, China;
    2. The Second Department of Surgery, Feicheng Hospital of Traditional Chinese Medicine, Tai'an Shandong 271600, China
  • Online:2022-04-16 Published:2022-05-16

Abstract: Objective To study the the therapeutic effect of levocetirizine, montelukast combined with BCG Bacillus Calmette-Guerin on chronic urticaria patients. Methods A total of 78 patients with chronic urticaria admitted to Feicheng Hospital Affiliated to Shandong First Medical University from February 2019 to November 2020 were selected. They were included and randomly divided into the observation group and the control group. Among them, 39 patients in the observation group received the therapy proctocol of levocetirizine, montelukast combined with BCG, while 39 patients in the control group received Bacillus Calmette-Guerin combined with montelukast. Quality of life score, treatment efficacy and clinical symptom subsidence time were administated between two groups. Results After treatment, the clinical symptom subsidence time in the observation group was significantly shorter than that in the control group (P<0.05). After treatment, the total efficiency of the observation group was significantly higher than that of the control group (P<0.05). After treatment, the quality of life score of the observation group was significantly higher than that of the control group (P<0.05). Conclusion The therapy protocol of levocetirizine, montelukast combined with BCG in chronic urticaria could significatly improve the clinical symptom subsidence time, improve the therapeutic effect and increase the quality of life score.

Key words: levocetirizine, montelukast, Bacillus Calmette-Guerin, chronic urticaria

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