Abstract: Objective To study the therapeutic effect of Qushi Weiling decoction combined with mometasone furoate cream on patients with eczema. Methods Selected 82 cases of patients with eczema who were treated in our hospital from May 2020 to May 2022, divided into two groups randomly. The control group was treated with mometasone furoate cream, while the observation group was treated with dehumidifying Weiling decoction. Evaluate the symptom scores and quality of life of both groups, and detect serum interleukin-2 (IL-2), aromatic hydrocarbon receptor (AhR) γ Interferon (IFN-γ) And interleukin-4 (IL-4) levels. Results After treatment, the skin lesion morphology, itching degree, skin exudation degree, and skin lesion area score of the two groups were significantly reduced (P<0.05), and the observation group had lower skin lesion morphology, itching degree, skin exudation degree, and skin lesion area score (P<0.05). After treatment, the serum levels of AhR and IL-4 in both groups were significantly reduced (P<0.05), IL-2, IFN-γThe level significantly increased (P<0.05), and the serum AhR and IL-4 levels in the observation group were significantly lower(P<0.05), IL-2,IFN-γ level was significantly higher (P<0.05). After treatment, the scores of economic burden, clothing, exercise, psychology, work learning, physiology, sexual life, daily life, social entertainment, and family relations in both groups were significantly reduced (P<0.05), and the scores of economic burden, clothing, exercise, psychology, work learning, physiology, sexual life, daily life, social entertainment, and family relations in the observation group were lower (P<0.05). Conclusion The combination of Qushi Weiling Tang and mometasone furoate cream has a significant therapeutic effect on patients with eczema, which can significantly alleviate symptoms, improve cytokine levels, and improve quality of life.

Key words: Dehumidifying Weiling Tang, Momoxone furoate cream, eczema