Abstract: Objective To analyze the diagnostic value of mammography combined with Doppler ultrasound in the screening of early breast cancer precancerous lesions. Methods From May 2020 to May 2023,120 patients of highly suspected breast cancer were selected. All the patients were diagnosed with Doppler ultrasound examination. This paper took pathological results as the gold standard, and the diagnostic accuracy, specificity and sensitivity were calculated according to different examination methods. Results 120 patients were diagnosed as 100 positive and 20 negative by pathological examination. Ultrasound examination was positive in 88 cases and negative in 32 cases. There were 95 cases with positive mammography and 25 cases with negative mammography. 98 cases were positive in the joint examination, and 22 cases were negative. The diagnostic accuracy of combined examination is 93.33%, sensitivity is 95.00%, and specificity is 85.00%; The diagnostic accuracy of ultrasound examination is 76.67%, the sensitivity is 80.00%, and the specificity is 60.00%; The diagnostic accuracy of breast molybdenum target examination is 87.50%, the sensitivity is 90.00%, and the specificity is 75.00%. The combined ultrasound examination has a significant advantage in the diagnostic results, and the difference in results is statistically significant (P<0.05). Conclusion The combination of mammography and Doppler ultrasound in the screening of early breast cancer precancerous lesions can effectively improve the accuracy of diagnosis.

Key words: screening of early breast cancer precancerous lesions, breast molybdenum target, doppler ultrasound