Abstract: Objective To explore the clinical value of nutrition and energy intake guidance on blood sugar control and disease prevention in patients with Gestational diabetes. Methods 80 pregnant women who were diagnosed with Gestational diabetes in the Second People's Hospital of Datong County, Qinghai Province from March 2020 to April 2022 were selected as the study subjects, 40 pregnant women who did not receive nutritional guidance from March 2020 to February 2021 were set as the control group, and 40 pregnant women who received nutritional guidance from March 2021 to April 2022 were set as the study group. The differences in BMI index, weight gain, Glucose test Fasting blood sugar The difference of blood glucose level 2 h after meal and Glycated hemoglobin level before delivery, the difference of qualified rate of blood glucose control and positive rate of urinary ketone body between the two groups of pregnant women, the difference of pregnancy outcome between the two groups of pregnant women, and the difference of complications between the two groups of pregnant women. Results There was no statistically significant difference in BMI index between the two groups of pregnant women before intervention (P>0.05). After intervention, the BMI index of the study group was lower than that of the control group (P<0.05), and the weight gain of the study group was lower than that of the control group (P<0.05). There was no significant difference in fasting blood glucose, 2 h postprandial glycemic and hemoglobin 1 c levels in the two groups (P>0.05), while fasting blood glucose, 2 h postprandial glyca 1 c levels in the two groups after intervention (P<0.05), and pregnant women in the study group were lower than the control group (P<0.05). The qualified rate of blood glucose control in the study group was significantly higher than that in the control group (P<0.05), and there was no statistically significant difference in the positive rate of urinary ketone bodies between the study group and the control group (P>0.05). The incidence of macrosomia in the study group was lower than that in the control group (P<0.05), and there was no statistically significant difference in other pregnancy outcomes between the groups (P>0.05). The total incidence of complications in the study group was significantly lower than that in the control group (P<0.05). Conclusion Nutrient and energy intake guidance for pregnant women with Gestational diabetes can help to control the weight of pregnant women, improve the qualification rate of blood sugar control for pregnant women, and to a certain extent, reduce the incidence of perinatal complications of pregnant women, which has a certain value for application.

Key words: nutrients, energy intake, gestational diabetes, body weight, blood sugar qualification rate, perinatal complications