Abstract: Objective To investigate the clinical efficacy of laparoscopic radical resection for colorectal cancer. Methods 100 colorectal cancer patients in Jining First People's Hospital from March 2015 to June 2020 were selected as the study subjects. According to the operation plan, the patients were divided into two groups. The control group (n=50) carried out open colorectal cancer radical surgery, and the observation group (n=50) carried out laparoscopic colorectal cancer radical surgery. The perioperative indexes, stress indexes and complications of the two groups were observed and compared. Results The operation time of the observation group was longer than that of the control group, and the hospitalization time of the observation group was shorter than that of the control group, but there was no statistical difference (P>0.05). The time of exhaust and eating after the operation was shorter than that of the control group, and the amount of bleeding during the operation was less than that of the control group, with statistical significance (P<0.05). There was no significant difference in WBC between the two groups before operation (P>0.05), but the WBC in the observation group was lower than that in the control group 2 days after operation (P<0.05). The incidence of complications in the observation group was lower than that in the control group, but there was no statistical significance (P>0.05). Conclusion Laparoscopic radical resection of colorectal cancer is less traumatic, has a faster recovery, has less impact on patients' stress, and there was no increased risk of complications.

Key words: lolorectal cancer, laparoscope, radical prostatectomy, complications, survival rates