ZHONGHUA YANGSHENG BAOJIAN ›› 2023, Vol. 41 ›› Issue (11): 1-4.

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Ultrasound-guided Type Ⅱ Thoracic Nerve Block In Breast Cancer Breast-conserving Surgery and Sentinel Iymph Node Biopsy

DENG Cheng-qi1,2,3,4,5, WANG Kai-yuan1,2,3,4,5, YU Kai-li1,2,3,4,5, WANG Gui-yue1,2,3,4,5, YIN Yi-qing1,2,3,4,5,*, HUANG Sheng-chuan6, Silangwangmu6   

  1. 1. Department of Anesthesiology, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China;
    2. National Clinical Research Center for Cancer, Tianjin 300060, China;
    3. Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China;
    4. Key laboratory of Cancer Prevention and Therapy, Tianjin 300060, China;
    5. Key laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin 300060, China;
    6. Department of Anesthesiology, Changdu Tibetan Medical Hospital, Changdu Xizang 854085, China
  • Online:2023-06-01 Published:2023-05-25

Abstract: Objective To evaluate the analgesic effect of ultrasound-guided type Ⅱ thoracic nerve block (PECS-Ⅱ) in breast cancer breast-conserving and sentinel lymph node biopsy. Methods Sixty patients undergoing elective unilateral breast-conserving surgery and sentinel lymph node biopsy in Tianjin Medical University Cancer Hospital from June to November 2022 were selected and divided into control group and PECS-Ⅱ group, 30 patients in each group using randomized number table. Control group was under general anesthesia with conventional laryngeal mask, while group P underwent ultrasound-guided PECS-Ⅱ block before awakening after surgery. Numerical rating scale (NRS) was used to assess the pain intensity in the breast and axilla of patients at 1 h, 6 h, 12 h and 24 h postoperatively. The 15-item Quality of Recovery (QoR-15) and the recording of total opioid consumption and adverse effects were assessed at 24 h postoperatively. Results There was no statistical difference between the two groups in terms of basic patient information. Compared with control group, the NRS scores were significantly lower in PECS-Ⅱ group at 1 h and 6 h after mastectomy (P<0.05), and in the axilla at 1 h, 6 h, 12 h, and 24 h after surgery (P<0.05). The 24 h postoperative QoR-15 score was significantly higher in PECS-Ⅱ group than in control group (P<0.05). Total opioid consumption and side effects were significantly lower in PECS-Ⅱ group than in control group 24 h postoperatively (P<0.05). Conclusion Ultrasound-guided type Ⅱ thoracic nerve block significantly reduced the intensity of breast and axillary pain 24 hours after breast cancer conservation and sentinel lymph node biopsy and improved the quality of patients' early postoperative recovery.

Key words: type Ⅱ, thoracic nerve block, breast cancer, breast-conserving surgery, sentinel lymph node biopsy, postoperative analgesia, early recovery quality

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