Abstract: Objective To understand the cognition and application of biological agents among dermatologists in Yunnan province. Methods From April to June, 2022, an electronic questionnaire was developed and distributed to dermatologists in Yunnan Province for anonymous investigation. Results 103 valid questionnaires were collected. The results showed that the doctor's awareness rate of biological agents was 99.03%, the utilization rate was 72.82%, and the remarkable efficiency rate of patients after use was 98.67%. Besides, the doctor's cognitive level and application ability were uneven, and it was easy to ignore the needs of patients' health, economy and care. The guarantee system of medical institutions and social policies needed to be improved, the concept of integrated traditional Chinese and western medicine treatment still needed to be strengthened, and large samples and multi-centers were needed in the future. Conclusion Yunnan dermatologists' cognition and application of biological agents have developed to some extent, but there are still some shortcomings. In the future, it is necessary to formulate comprehensive industry and regional standards, standardize the specialist training of dermatologists, and strive to make biological agents develop in the direction of precision medicine.

Key words: Yunnan, dermatologist, biological agents, questionnaire survey