Abstract: Objective To explore the impact of 4R crisis management on the implementation of prevention and control measures for multidrug-resistant bacterial infections and the incidence of infections. Methods A total of 370 medical workers from Wujin Hospital affiliated to Jiangsu University from April 2020 to April 2023 were selected as the study subjects and divided into two groups according to different management plans. 180 control group received routine training on multidrug-resistant bacteria, and 190 study group received 4R crisis management on the basis of the control group. Before and after the intervention, the knowledge and implementation of the prevention and control measures of multi-drug-resistant bacteria, hand hygiene and multi-drug-resistant bacteria infection in different samples were compared between the two groups. Results There was no significant difference in the knowledge of prevention and control of multidrug-resistant bacteria in the two groups before intervention (P>0.05). After intervention, the knowledge of medical staff in the study group was higher than that in the control group (P<0.05). The hand hygiene compliance of medical staff in different positions in the study group was higher than that in the control group (P<0.05). There was no difference in the incidence of multidrug-resistant bacteria infection between the two groups before intervention (P>0.05). After intervention, the incidence of multidrug-resistant bacteria infection in the study group (3.60%) was lower than that in the control group (8.40%) (P<0.05). Conclusion The 4R crisis management model has positive value in improving the implementation of prevention and control measures for multidrug-resistant bacterial infections among medical workers. It can reduce the detection rate of multidrug-resistant bacteria in patient fluids. It has good promotion and application value.

Key words: 4R crisis management mode, infection with multidrug-resistant bacteria, prevention and control measures, hospital infection rate