ZHONGHUA YANGSHENG BAOJIAN ›› 2024, Vol. 42 ›› Issue (6): 164-168.

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The Value of 3D-ASL Technology in Postoperative Recurrence of High-grade Glioma

MENG Fan-ran1, WANG Wei1,*, FENG Hui-yu1, MENG Shao-lin2, HE Chen-xi1, XU Wei1, GAO Fei1   

  1. 1. Department of Medical Imaging, Zhuozhou Hospital, Zhuozhou Hebei 072750, China;
    2. Department of Radiotherapy, Hebei Yizhou Cancer Hospital, Zhuozhou Heibei 072750, China
  • Online:2024-03-16 Published:2024-03-07

Abstract: Objective To explore the application value of three-dimensional arterial spin labeled perfusion imaging (3D-ASL) in postoperative tumor recurrence of high-grade gliomas (HHG). Methods Retrospective analysis of 31 patients with postoperative recurrence of advanced glioblastoma in our hospital from December 2019 to December 2021. All patients underwent magnetic resonance plain scan, enhanced scan, and 3D-ASL examination to measure the recurrence area of high-grade gliomas after surgery, as well as the cerebral blood flow (CBF) of contralateral normal brain tissue, for statistical analysis. Diagnosis was made by combining conventional magnetic resonance imaging and conventional magnetic resonance imaging with 3D-ASL imaging, and the diagnostic accuracy was analyzed for statistical comparison. Results The CBF in the postoperative recurrence group of high-grade gliomas was significantly higher than that in the normal group, with a significant statistical difference (P<0.05). The diagnostic accuracy of conventional magnetic resonance imaging combined with 3D-ASL film reading in diagnosing postoperative recurrence of high-grade gliomas was significantly improved compared to conventional magnetic resonance imaging, and there was a significant statistical difference between the two (P<0.05). Conclusion 3D-ASL technology has high diagnostic efficacy in postoperative recurrence of high-grade gliomas and has important clinical application value.

Key words: magnetic resonance imaging, arterial spin labeled perfusion imaging, high-grade gliomas, postoperative recurrence

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