Abstract: Objective Explore the distribution of multidrug-resistant bacterial infections in a tertiary traditional Chinese medicine hospital in Gansu Province. Methods The clinical test results of multidrug-resistant bacteria from a tertiary traditional Chinese medicine hospital in Gansu Province from 2019 to 2022 were selected, used the "Hospital Infection and Infectious Disease Real Time Monitoring Platform" to retrospectively analyze the MDRO detection rate, key monitoring MDRO distribution composition, infection departments, and source distribution of infection samples. Results A total of 1 360 MDRO positive cases were collected after eliminating duplicate samples from 2019 to 2022. The distribution of MDRO under key monitoring was in the order of carbapenem resistant Acinetobacter baumannii (CR-AB), methicillin resistant Staphylococcus aureus (MRSA), carbapenem resistant Pseudomonas aeruginosa (CR-PA), carbapenem resistant Enterobacteriaceae (CRE), vancomycin resistant Enterococcus (VRE), the detection rate of CR-AB showed a decreasing trend; The key monitoring departments for MDRO infection were widely distributed, with infection rates mainly in the departments of Intensive Care Medicine, Osteomyelitis, Pulmonary Disease and Encephalopathy, accounted for 34.71%, 10.51%, 7.79% and 6.47%. The clinical test specimens were mainly composed of sputum and wound secretions, accounted for 45.00% and 26.62%. Conclusion The infection of multidrug-resistant bacteria in this hospital has been on the rise in recent years, and further strengthening of relevant infection prevention and control work is needed

Key words: traditional Chinese medicine medical institutions, multi drug resistant bacteria, hospital infection prevention and control