Observation of Clinical Efficacy of Traditional Chinese Medicine Intervention under Thought of Acrid Dispersing and Bitter Descending on Subclinical Hypothyroidism of Hashimoto's Thyroiditis

Abstract

Abstract: Objective To clinically observe and evaluate the intervention efficacy of Chinese herbal medicine under thought of acrid dispersing and bitter descending on subclinical hypothyroidism of Hashimoto's thyroiditis. Methods From January 2023 to January 2024, 30 patients with subclinical hypothyroidism of Hashimoto's thyroiditis treated at Tongzhou Hospital, Dongzhimen Hospital, Beijing University of Chinese Medicine were randomly divided into control group and treatment group according to a random number table, with 15 cases in each group. The control group was given oral levothyroxine sodium tablets plus Chinese medicine placebo, and the treatment group was given Chinese herbal medicine treatment with Chinese medicine under thought of acrid dispersing and bitter descending on the basis of Western medicine treatment in the control group, with a course of 8 weeks. The changes in thyroid hormone levels and thyroid antibodies levels before and after intervention were compared between the two groups. Results Compared with before intervention, both the treatment group and the control group could effectively reduce the levels of thyroid stimulating hormone (TSH) after intervention(P<0.05), and the total effective rate of the treatment group was significantly higher than that of the control group(P<0.05). After the intervention, the TCM total symptom scores in both groups were significantly reduced compared to before the intervention, and the treatment group showed an improvement in the total symptom score after the intervention, which was significantly better than that of the control group(P<0.05). Conclusion Chinese herbal medicine under thought of acrid dispersing and bitter descending can improve the levels of TSH in subclinical hypothyroidism of Hashimoto's thyroiditis and enhance the clinical efficacy.

Key words: Thought of acrid dispersing and bitter descending, Chinese herbal medicine, Hashimoto's thyroiditis, subclinical hypothyroidism, clinical efficacy observation

CLC Number:

R259

ZHOU Jing-xin, MIAO Juan, JIN Jian, YANG Jie, LU Yi-zhen, GONG Yan-bin. Observation of Clinical Efficacy of Traditional Chinese Medicine Intervention under Thought of Acrid Dispersing and Bitter Descending on Subclinical Hypothyroidism of Hashimoto's Thyroiditis[J]. ZHONGHUA YANGSHENG BAOJIAN, 2024, 42(24): 1-4.

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