Abstract: Objective This study aimed to evaluate the efficacy of San Huang Si Wu Tang in treating chronic cervicitis. Methods A randomized number table method was employed to select 80 patients with chronic cervicitis treated at the Affiliated Hospital of Jiujiang University from January 2022 to December 2023. Patients were randomly allocated to either the conventional Western medicine treatment group (control group) or the San Huang Si Wu Tang treatment group (Observation group) to compare the impact of the two treatment regimens on clinical efficacy. The evaluation indicators included improvement of clinical symptoms, Traditional Chinese Medicine (TCM) syndrome score, repair of cervical erosion, changes in serum inflammatory factor levels, and the incidence of treatment-related adverse events. Results The overall effectiveness rate of the experimental group was significantly higher than that of the control group, with a statistically significant difference (P<0.05). The proportion of cervical erosion recovery to normal in the experimental group was also significantly higher than that in the control group (P<0.05). Moreover, compared to the control group, the experimental group showed more significant improvements in TCM syndrome scores and reductions in serum inflammatory factor levels (P<0.05), with a lower incidence of treatment-related adverse events (P<0.05). Conclusion San Huang Si Wu Tang demonstrated significant therapeutic effects in treating chronic cervicitis, effectively promoting the repair of cervical erosion, reducing serum inflammatory factor levels, and possessing high safety.

Key words: San Huang Si Wu decoction, chronic cervicitis, clinical study, efficacy, safety