Clinical Evaluation of Different Recanalization Methods in Patients with Acute Cerebral Infarction

Abstract

Abstract: Objective To compare the clinical efficacy of intravenous thrombolysis, mechanical thrombectomy and bridging in the treatment of acute cerebral infarction. Methods From January 2016 to January 2019,78 patients with acute cerebral infarction were selected from the Department of Neurology, the Second Affiliated Hospital of Luohe Medical Higher Vocational School, Henan Province. They were divided into intravenous thrombolysis group (n=30) and mechanical thrombectomy group (n=25) according to different therapeutic methods, venous Thrombolysis Bridging Group (n=23) . The National Institutes of health stroke scale (NIHSS) scores before treatment, 24 hours after treatment, 14 days after treatment and Modified Rankin Scale(mRS) Scores at 90 days after treatment were compared in each group to evaluate the therapeutic effect. The patient's curative effect was compared with the analysis of NIHSS within 24 hours in the later period of treatment. Results Compared with before treatment, NIHSS scores of mechanical thrombectomy group and bridging treatment group were significantly lower 24 h and 14 d after treatment (P<0.05). NIHSS scores of mechanical thrombectomy group and bridging treatment group were lower than those of intravenous thrombolysis group (P<0.05), while NIHSS scores of mechanical thrombectomy group and bridging treatment group were similar at each time point after treatment, without statistical significance (P>0.05). After 90 days, mRS score of bridging group and mechanical thrombectomy group was significantly lower than that of intravenous thrombolysis group (P<0.05), but there was no significant difference between bridging group and mechanical thrombectomy group (P>0.05). Conclusion Intravenous thrombolysis, mechanical thrombectomy or bridging therapy can improve the neurological function of patients with acute cerebral infarction. Mechanical thrombectomy and bridging therapy can improve the neurological function earlier and have better long-term prognosis.

Key words: acute cerebral infarction, intravenous thrombolysis, mechanical thrombectomy, bridging therapy

CLC Number:

R743.33

ZHENG Jian-xin, ZHANG Shuai-jie, SUN Wei-li. Clinical Evaluation of Different Recanalization Methods in Patients with Acute Cerebral Infarction[J]. ZHONGHUA YANGSHENG BAOJIAN, 2023, 41(4): 4-7.

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