Effect of Hyperbaric Oxygen Rehabilitation on Stress Response and Cognitive Function of Patients with Traumatic Brain Injury

Abstract

Abstract: Objective To observe the effect of hyperbaric oxygen rehabilitation technology on traumatic brain injury and its effect on patients' stress response and cognitive function. Methods 112 patients with traumatic brain injury admitted to Heze municipal hospital from August 2020 to January 2022 were selected and divided into the comparison group (56 cases) and the study group (56 cases) by drawing lots. The two groups of patients received routine treatment first. The study group was treated with hyperbaric oxygen rehabilitation technology. Functional independence scale (FIM) was used to evaluate their independent living ability, neurobehavioral cognitive scale (NCSE) was used to evaluate their cognitive function, and malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and other indicators were detected by enzyme immunoassay to evaluate their stress response. The clinical cure rates of the two groups were statistically analyzed and compared. Results Before intervention, there was no difference between the two groups in FIM score, NCSE score and oxidative stress response (P>0.05). After intervention, the FIM and NCSE scores of the study group were significantly higher than those of the control group (P<0.05). After intervention, the level of SOD and GSH-PX of the two groups were increased and the level of MDA of the two groups were decreased (P<0.05); the level of SOD, GSH-PX and MDA of the study group were higher than those of the control group (P<0.05). The clinical cure rate of the study group was higher than the control group (P<0.05). Conclusion Hyperbaric oxygen rehabilitation is effective in the treatment of traumatic brain injury, which can effectively reduce stress response and improve cognitive function of patients.

Key words: hyperbaric oxygen, craniocerebral trauma, oxidative stress response, cognitive function

CLC Number:

R651.1

GU Li-ming. Effect of Hyperbaric Oxygen Rehabilitation on Stress Response and Cognitive Function of Patients with Traumatic Brain Injury[J]. ZHONGHUA YANGSHENG BAOJIAN, 2023, 41(3): 19-22.

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