Abstract: Objective To investigate the application value of transthoracic echocardiography and double-source spiral CT in preoperative diagnosis of congenital heart disease in children. Methods A total of 66 cases of suspected congenital heart disease who were hospitalized and treated in Lanzhou First People's Hospital from February 2019 to December 2022 were collected as the study subjects. Before these patients, transthoracic echocardiography and double-source spiral CT were performed, and the surgical. Results were taken as the gold standard, comparing the subjective scores of image quality between ultrasound and CT groups, radiation dose and noise and signal-to-noise ratio of preoperative dual source spiral CT, surgical diagnosis, and the diagnostic value of transthoracic echocardiography and dual source spiral CT in children with congenital heart disease. Results The subjective score of the image quality of the structure, the near coronary artery between the ultrasound and CT were>4 points, and the contrast showed no significant difference (P>0.05). At the CT test, the dose length product was (13.20±2.18) mGy, the effective dose was (0.27±0.03) mSv, the cardiac macro-vessel CNR value was (8.22±0.47). The surgical diagnosis was 38 cases of congenital heart disease, included 15 atrial septal defects, 9 single atrium, 6 ventricular septal defects, 3 valvular lesions, 2 triplicate hearts, 2 single ventricles and 1 endocardial pad defect. In ultrasound examination, 36 cases of congenital heart disease and 2 cases of atrial septal defect were missed, 38 cases of CT with no missed misdiagnosis. Transthoracic echocardiography with bisource spiral CT had 94.74% and 100.00% sensitivity and 100.00% and 100.00% for preoperative diagnosis, and the ROC curve showed that the area under the curve predicted by transthoracic echocardiography was 0.963 and 1.000, respectively. Conclusion The application of transthoracic echocardiography and double-source spiral CT in preoperative diagnosis of congenital heart disease in children has high sensitivity and specificity, and both can provide a certain basis for clinical diagnosis and treatment of congenital heart disease.

Key words: transthoracic echocardiography, dual-source spiral CT, congenital heart disease, children, sensitivity, specificity, radiation dosage