Abstract: Objective To analyze the efficacy of Huangqi Guizhi Wuwu Decoction in the treatment of peripheral neuritis after chemotherapy. Methods From January 2021 to May 2022, 60 patients with peripheral neuritis after chemotherapy who were treated in Heilongjiang Provincial Hospital were selected as the study subjects. They were randomly divided into two groups according to the digital grouping method: the external washing group with traditional Chinese medicine (30 cases) and the control group (30 cases). The control group patients were given routine treatment and vitamin treatment, and the external washing group patients were treated with Huangqi Guizhi Wuwu Decoction on the basis of the control group. Compare the overall efficacy, visual analog scale (VAS), and serum interleukin-1 of the two groups of patients before and after treatment β (IL-1β), Tumor necrosis factor-α(TNF-α) Level improvement. Results The total effective rate of patients in the external washing group was significantly higher than that in the control group (P<0.05). Before treatment, there was no significant difference in serum IL-1β, TNF-α levels and pain scores between the two groups (P>0.05). After intervention, serum IL-1β、 TNF-α and pain scores were significantly decreased (P<0.05), with a significant difference compared to before intervention (P<0.05), and the serum IL-1β, TNF-α of patients in the external washing group of traditional Chinese medicine was also significantly decreased (P<0.05). The decrease in pain scores was significantly greater in the control group than in the control group (P<0.05). Conclusion Huangqi Guizhi Wuwu Decoction has a good therapeutic effect on peripheral neuritis after chemotherapy, which can effectively improve the inflammatory status of the body, reduce the degree of pain, and improve the overall treatment effect of patients. It is a safe and efficient treatment method.

Key words: Huangqi Guizhi Wuwu Decoction, external washing, chemotherapy, peripheral neuritis, curative effect