Abstract: Perimenopausal syndrome (PMS) is refered to a clinical syndrome in women with a lot of speculations that appear before, during and after the onset of menopause, caused by estrogen level fluctuations or lower a series of physical. Theory in traditional Chinese medicine for PMS believes that kidney deficiency is the basic pathogenesis of this disease, and can accumulate the heart, liver and spleen. Professor Fang Zhaohui, who has dealed with PMS for many years, believes that the deficiency of kidney Yin is the main pathogenesis of perimenopausal hyperhidrosis. The deficiency of kidney Yin causes blood deficiency to generate heat, which causes disease through internal disturbance. Therefore, clinical treatment should be based on nourishing Yin and lowering fire, taking nourishing the heart and calming the mind as therapeutic principles. The dialectical emphasis is on distinguishing Yin and Yang as well as deficiency and excess. The deficiency patients should be treated by invigorating Qi, nourishing Yin, replenishing blood and harmonizing Yingwei according to the different syndroms. Those who are real should clear the liver, diarrhoea and heat, dehumidify and camp; those who are mixed with virtual and real should distinguish the primary and secondary, and take appropriate attention to it. Use the medicine with the certificate, add astringent and astringent products as appropriate, enhance the antiperspirant effect, and achieve a good curative effect.

Key words: perimenopausal syndrome, excessive sweating, nourishing Yin and lowering fire, clinical experience