ZHONGHUA YANGSHENG BAOJIAN ›› 2023, Vol. 41 ›› Issue (16): 1-4.

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Clinical Study on Yiyun Materia Medica Yin in Auxiliary Improving Ovarian Function

KOU Qiu-ai1, XIA Li-ying1, WANG Wen qian2,*, YANG Jia-xi2, SUN Wen-ting1, Zhang Ying3, YUAN Jing-quan3, YANG Yi-ting3   

  1. 1. Health Care Research Center of Traditional Chinese Medicine,Xiyuan Hospital, Chinese Academy of Chinese Medical Sciences, Beijing, 100091, China;
    2. Clinical School of Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China;
    3. Infinitus (China) Co., LTD, Guangzhou Guangdong, 510405, China
  • Online:2023-08-16 Published:2023-08-08

Abstract: Objective To evaluate the auxiliary effect of Yiyun Materia Medica Yin in improving the ovarian reserve, so as to provide a way for early treatment of DOR. Methods A total of 64 subjects with diminished ovarian reserve who were recruited were enrolled in this study from August 2020 to April 2021.They were assigned to two groups: the experimental group and the control group, according to the sequence, with 32 cases in each group. The trail continued twelve weeks. After the trail,the sex hormone levels, number of bilateral sinus follicles, sexual life indicators, menstrual indicators and symptom and sign scores of the two groups of subjects were compared between the two groups before and after treatment. Result Before the trail, there was no significant difference in all indicators between the two groups(P>0.05). After the trail, the FSH in the experimental group was lower than before, and the scores of AFC, AMH, sexual life indicators, symptoms and signs were improved compared with at the begining of the trail. The FSH, sexual life indicators, symptoms and signs were significantly different from those in the control group after the trail (P<0.05). Conclusion Yiyun Materia Medica Yin can effectively improve the decreased ovarian reserve, and the safety is good.

Key words: decreased ovarian reserve, Yiyun Materia Medica Yin, clinical research

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