Study and Application of Drug Balloon in Severe Coronary Stenosis

Abstract

Abstract: Objective To investigate and analyze the research and application values of drug balloon in severe coronary stenosis. Methods From January 2019 to April 2022, 153 cases of patients with severe coronary stenosis diagnosed and treated in our hospital were selected as the study subjects. Accorded to the 1∶1 random number table, the patients were divided into drug balloon group (77 cases) and drug stent group (76 cases). The drug stent group were treated with drug eluting stent therapy, and the drug balloon group were treated with drug balloon. The prognosis of the patients in the two groups were recorded and followed up. Results 1 month after treatment, the treatment success rate of drug balloon groupwas 98.70%, compared with 90.79% in the drug stent group, there was no statistical significance (P>0.05). 1 month after treatment, LVEF was significantly higher than before treatment (P<0.05), LV end-diastolic internal diameter was significantly lower than before in both groups (P<0.05), 1 month after treatment, LVEF in the drug balloon group was higher than that in the drug stent group (P<0.05), and LV end-diastolic internal diameter was lower than the stent group (P<0.05).The 6-min walk test results at 1 month after treatment were higher than before treatment (P<0.05), and the drug balloon group was significantly higher than the drug stents (P<0.05).The incidence rates of adverse cardiovascular events such as myocardial infarction, coronary stent restenosis, revascularization, and cardiac death at 6 months after treatment in the drug balloon group, which compared to the drug stent group were not significantly difference (P>0.05). Conclusion The application of drug balloon in severe coronary stenosis can improve the cardiac function of patients, increase the 6-minute walking test distance of patients, it also has good safety, especially in patients with bifurcation disease, small vessel disease, in stent restenosis and high bleeding score.

Key words: drug balloon, severe coronary stenosis, cardiac function, 6 min walking test, cardiovascular adverse events

CLC Number:

ZHANG Kai-ping, HUANG Ping, LIANG Hong-tao, CHAI Fang-yun, LI Pan. Study and Application of Drug Balloon in Severe Coronary Stenosis[J]. ZHONGHUA YANGSHENG BAOJIAN, 2023, 41(13): 12-15.

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