Abstract: Objective To investigate the application value of personalized “shortening warm ischemia time” technique in laparoscopic nephrectomy for patients with T1 renal tumors. Methods A total of 126 patients with T1 stage renal tumor who were admitted to Yellow River Central Hospital from March 2019 to March 2021 were selected for retrospective analysis, and divided into conventional group (n=62) and individualized technique group (n=64), perioperative indicators, renal function levels, complications and recurrence were compared between the two groups. Results There was no significant difference in intraoperative blood loss, operation time, negative margins rate and hospital stay between the two groups (P>0.05); Because subgroups 1, 2, and 3 in the individualized technology group did not block the renal artery, there was no warm ischemia time, and the warm ischemia time in subgroups 4 and 5 was shorter than that in the conventional group (P<0.05); There was no statistical significance difference in the levels of blood creatinine (Scr) and glomerular filtration rate (eGFR) in the preoperative group (P>0.05). After treatment, the Scr and eGFR in the conventional group were decreased compared with those before treatment (P<0.05), and there was no statistically significant difference change in the personalized technology group (P>0.05), the levels of Scr and eGFR in the individualized technique group were higher than those in the conventional group (P<0.05); the complication rate in the individualized technique group was lower than the conventional group (P<0.05). Comparison of recurrence rates between the two groups, the difference was not statistically significant (P>0.05). Conclusion The improved laparoscopic nephrectomy based on the personalized “shortening warm ischemia time” technique is beneficial to the recovery of patients with T1 renal tumors, and maximizes the protection of renal function, with fewer complications and high safety.

Key words: renal neoplasms, laparoscopy, nephrectomy, individualization, warm ischemia time