Abstract: Objective To observe the clinical efficacy of intra-arterial thrombolysis combined with intravascular stenting applied to patients with acute cerebral infarction. Methods Sixty-eight patients with acute cerebral infarction in Pingdu Hospital of Chinese Medicine from October 2018 to January 2021 were divided into control group and observation group equally. The patients in control group were treated with intra-arterial thrombolysis, whereas the patients in observation group were subject to intra-arterial thrombolysis combined with intravascular stenting. The incidence of postoperative side effects and the total response rate were compared between the two groups. The hemodynamic indexes, serum-related indexes and life quality of the two groups before and after treatment were compared. The neural function deficiency of the two groups at different stages during treatment was compared. Results The incidence of side effects in observation group was lower than control group, while the total response rate of observation group was higher than control group (P<0.05). Before treatment, there was no significant difference in hemodynamic indexes, serum-related indexes, life quality and neural function deficiency between the two groups (P>0.05). However, after treatment, the hemodynamic indexes, serum-related indexes and neural function deficiency scores in the observation group were lower than those in the control group, and the quality of life was better than that in the control group (P<0.05). Conclusion The application of intra-arterial thrombolysis combined with intravascular stenting to patients with acute cerebral infarction could significantly improve the hemodynamics and serum-related indexes of patients, attenuate neural function deficiency, possess high therapeutic safety and efficacy, and enhance the overall therapeutic effect and life quality of patients.

Key words: intra-arterial thrombolysis, intravascular stenting, acute cerebral infarction