Abstract: Objective To observe and investigate the clinical role of psychological nursing intervention in improving the emotions and enhancing the quality of life of patients with leukemia. Methods A total of 72 leukemia patients admitted to the Second People's Hospital of Lianyungang from June 2019 to May 2021 were observed. They were divided into the control group and the observation group using a random number table, with 36 cases in each group. The control group was given conventional care, and the observation group conventional care plus psychological nursing intervention. The emotional changes and quality of life of the patients in the observation group were compared to understand the clinical value of different nursing care approaches. Results The Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS) scores of patients in the observation group after nursing were lower than those before nursing, and significantly lower than those in the control group after nursing (P<0.05); the scores of material life, psychological function, physical function and social function of patients in the observation group after nursing were significantly higher than those before nursing and those in the control group after nursing (P<0.05). Conclusion Psychological nursing intervention has a significant effect on leukemia patients, which can improve their unhealthy emotions and enhance their quality of life, so it is worthy of widespread promotion in clinical settings.

Key words: leukemia, psychological nursing intervention, emotional status, quality of life