Abstract: Objective To study the clinical effect of severe pneumonia pneumonia in patients with respiratory distress syndrome (respiratory distress syndrome; respiratory-distress syndrome, ARDS). Methods The study case screening for December 2021 to December 2023 in 8 intensive pneumonia with ARDS of 80 cases, group way is random number table method, group includes observation group 40 cases and 40 cases, the two groups of patients with lung double treatment, the control group patients take supine position, the observation group patients accept prone position, compare the two groups of treatment effect. Results After treatment, compared with before treatment, the oxygen concentration fraction and positive end expiratory pressure ventilation levels in both groups decreased, and the observation group patients showed a decrease compared to the control group; The arterial oxygen partial pressure and oxygenation index were all elevated, and the observation group patients were compared with the control group, with significant differences in results between the groups (P<0.05).The mechanical ventilation time and ICU stay time of the observation group patients were shorter than those of the control group, and the mortality rate at 28 days was lower than that of the control group ( P<0.05); The incidence of adverse reactions in the observation group was only 2.50%, significantly lower than the 15.00% incidence of adverse reactions in the control group (χ²=3.913, P=0.047). Conclusion In the treatment of severe pneumonia and ARDS patients, it can further improve the treatment effect, significantly improve the oxygenation index of patients, reduce the occurrence of adverse reactions in the treatment process, and improve the disease control effect.

Key words: severe pneumonia, ARDS, prone lung reconstruction, effect study