Abstract: Objective To explore the combination of Shexiang Baoxin Pills β The application effect of receptor blockers on coronary heart disease with ventricular premature beats and its impact on electrocardiogram indicators. Methods A total of 80 patients with coronary heart disease complicated with ventricular premature beat admitted to Dingxi Hospital of traditional Chinese medicine in Gansu Province from May 2018 to April 2023 were selected for research and analysis. All patients were divided into observation group and control group by lottery, with 40 cases in each group. The control group received routine treatment β Metoprolol, a receptor blocker, was used in the treatment group, and Shexiang Baoxin Pill was added in the observation group on the basis of the control group. The clinical efficacy, cardiac function changes and 24-hour dynamic electrocardiogram monitoring results of the two groups were compared before and after treatment. Results The total effective rate of the observation group was significantly higher than that of the control group (P<0.05); After treatment, the left ventricular ejection fraction (LVEF) of the two groups increased, and the observation group was significantly higher than that of the control group, while the levels of left ventricular end systolic volume (LVESV) and left ventricular end diastolic volume (LVEDV) decreased, and the observation group was lower than that of the control group (P<0.05); After treatment, QT dispersion (QTd), ventricular depolarization to complete repolarization time (QT interval) and ventricular premature beat frequency in the two groups were decreased, and the observation group was lower than the control group, while atrioventricular conduction time (PR interval) and ventricular premature beat index were increased, and the observation group was higher than the control group (P<0.05). Conclusion Combination of Shexiang Baoxin Pill β The therapeutic effect of receptor blockers on coronary heart disease with ventricular premature beats is significant, which can improve the patient's heart function level, improve the patient's electrocardiogram diagnosis results, and improve the symptoms of ventricular premature beats.

Key words: Shexiang Baoxin Pill, β receptor blockers, coronary heart disease, ventricular premature beats, electrocardiogram, cardiac function