Abstract: Objective To explore the difference of clinical effect between ultrasound-guided microwave ablation and traditional thyroid surgery in the treatment of thyroid benign tumor. Methods Eighty patients with thyroid benign tumor diagnosed by general surgery department of the Second People's Hospital of Jining City from January 2020 to January 2023 and conforming to the surgical indications were included as the analysis objects. Based on the difference of surgical treatment schemes,the patients were divided into the traditional group and the observation group, with 40 cases in each group.The traditional group patients were treated with traditional thyroid surgery,while the observation group patients were treated with ultrasound guided microwave ablation.The therapeutic effect was evaluated from the therapeutic effect,clinical indicators, complications and Thyroid hormones indicators of the two types of surgery. Results The effective rate of thyroid benign tumor treatment in the observation group was higher than that in the traditional group, with a statistically significant difference (P<0.05). In terms of surgical indicators, the observation group had shorter surgical time and hospital stay than the traditional group, and the intraoperative blood output was lower than the traditional group,with a statistically significant difference (P<0.05). The incidence of postoperative complications in the observation group was lower than that in the traditional group, and the difference was statistically significant (P<0.05). There was no statistically significant difference in the detection of serum free Triiodothyronine (FT3), serum free Tetraiodothyronine(FT4), and Thyroid-stimulating hormone (TSH) before operation between the two groups. The FT3 and FT4 indexes of patients in the observation group after operation were higher than those in the traditional group, and the TSH indexes were lower than those in the traditional group,with a statistically significant difference (P<0.05). Conclusion The efficacy and safety of ultrasound-guided microwave ablation for patients with thyroid Benign tumor can meet the clinical needs and reduce the possible adverse effects on patients.

Key words: ultrasound, microwave ablation, traditional surgery, thyroid gland, benign tumor