Abstract: Objective The role of anticardiolipin antibody level in residual abortion was explored, and its correlation with the level of anti-endometrial antibody (the endometrial antibodies, EMAb) was analyzed. Methods A total of 200 patients with missed abortion who received treatment in our hospital from October 2019 to August 2022 were selected as the study group, and 200 normal pregnant women who received physical examination in our hospital at the same time were selected as the control group. By comparing the differences in serum antiardiolipin antibody level and EMAb level between the two groups, the correlation between the antianticardiolipin antibody level and EMAb level was explored, and the diagnostic efficacy of the anticardiolipin antibody level and EMAb was calculated by drawing ROC (Receiver operating characteris) curve. Results The levels of anticardiolipin antibody IgG, anticardiolipin antibody IgA, anticardiolipin antibody IgM, and EMAb in the study group were significantly higher than those in the control group (P<0.05). The serum EMAb levels of patients in the study group were positively correlated with their levels of anticardiolipin IgG antibodies, IgA antibodies, and IgM antibodies (r=0.552, r=0.586, r=0.417, P<0.05). The area under curve (AUC) of serum anticardiolipin IgG antibodies, anticardiolipin IgA antibodies, anticardiolipin IgM antibodies, and EMAb for missed abortion were 0.930 (95%CI: 0.886~0.974, P<0.05), 0.972 (95%CI: 0.940~1.000, P<0.05), 0.990 (95%CI: 0.979~1.000, P<0.05), and 0.959 (95%CI: 0.927~0.990, P<0.05). Conclusion The level of anti-cardiolipin antibody and EMAb level in women with retained abortion were significantly increased, and the level of anti-cardiolipin antibody showed a positive correlation with EMAb, and the level of anti-cardiolipin antibody and EMAb had certain reference value for retained abortion.

Key words: anticardiolipin antibody level, missed miscarriage, anti endometrial antibodies, diagnostic effectiveness, correlation analysis