ZHONGHUA YANGSHENG BAOJIAN ›› 2024, Vol. 42 ›› Issue (2): 81-84.

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Analyzing the Pathogenesis of Steroid-Induced Necrosis of the Femoral Head Based on the "Medicinal Toxins Theory"

ZHOU Chang-an1,2, HUANG Qiong1   

  1. 1. Medical Science Department, Hubei University for Nationalities, Enshi Hubei, 445000, China;
    2. Department of Orthopedics, Gaoqing County Hospital of Traditional Chinese Medicine, Zibo Shandong, 256399, China
  • Online:2024-01-16 Published:2024-01-17

Abstract: Medicine evil is the human physiological and biochemical dysfunction caused by the processing or improper use of drugs.Steroid-induced Necrosis of the Femoral Head " refers to the pathological process in which high doses of hormones lead to the death of the active components of the femoral head. Drawing upon the principles of the "Medicinal Toxins Theory" and acknowledging the detrimental effects of glucocorticoids on the femoral head, this study delves into the pathogenesis of steroid-induced necrosis of the femoral head through the lens of traditional Chinese medicine. Within this framework, hormones are viewed as medicinal toxins that play a significant role in influencing the development of steroid-induced necrosis. This influence is attributed to factors such as the stagnation of Qi and blood, the amalgamation of fluid imbalance, phlegm, and stasis, as well as internal organ impairment impacting the liver, spleen, and kidney, ultimately leading to bone malnutrition and necrosis over time.In terms of treatment, the focus lies on fundamental methods that involve promoting Qi circulation, dispelling blood stasis, resolving phlegm, and replenishing kidney function. The ultimate goal is to expel toxins and alleviate symptoms. This theory establishes a solid theoretical foundation for future experimental validation and clinical approaches.

Key words: traditional Chinese medicine, medicinal toxins, hormones, steroid-induced necrosis of the femoral head, pathogenesis.

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