Abstract: Objective To investigating the relation between fundic glandular polyps and colorectal polyps. Methods One hundred patients who were identified with fundic gland polyps by both gastroscopy and pathology and who underwent colonoscopy at the same time (no more than six months between the two examinations) as a case group and 200 patients who underwent gastroscopy at the same time and did not have fundic gland polyps as a control group were randomly assigned to the study from May 2021 to December 2022 at the Hospital of Combined Traditional Chinese Medicine Affiliated to the Nanjing University of Traditional Chinese Medicine. The gender distribution, age distribution, total cholesterol, triglycerides, location, number and diameter of fundic gland polyps, and type, number, diameters and sites of colorectal polyps were analysed. Results The rate of colorectal polyp detected in the category of cases was higher than that in the control group, and the difference was statistically significant (P<0.05). The percentage of colorectal polyps detected was higher in patients with fundic gland polyps aged ≥45 years (P<0.05), and were more likely to be detected in patients with combined hyperlipidemia (P<0.05). Conclusion Patients with fundic gland polyps are more likely to develop colorectal polyps than those without fundic gland polyps. Age≥45 years and high blood lipids are risk factors for combined colorectal polyps in patients with fundic gland polyps.

Key words: fundic gland polyps, colorectal polyps, gastroenteroscopy