Abstract: Objective To explore the application effect of resistance training combined with aerobic training on ischemic stroke and its impact on neurological deficits. Methods Selected 100 patients with ischemic stroke admitted to our hospital as the research subjects from October 2021 to October 2022. They were randomly divided into an observation group and a control group using a lottery method, with 50 patients in each group. The control group patients received routine rehabilitation training, while the observation group received resistance training combined with aerobic training on the basis of routine rehabilitation training. The changes in neurological function, motor function, and quality of life before and after treatment were compared between the two groups of patients. Results After treatment, the levels of NSE, NGF, BDNF in the two groups decreased, and the levels of BDNF in the observation group was higher than that in the control group (P<0.05). After treatment, the Barthel index and Fugl Meyer score of the two groups of patients increased significantly, and the observation group was higher than the control group (P<0.05). The quality of life related scores of both groups of patients increased after treatment, and the observation group was higher than the control group (P<0.05). Conclusion The combination of resistance training and aerobic training can improve the neurological deficits of ischemic stroke patients, promote the recovery of motor function, and improve their quality of life, which is worthy of clinical application .

Key words: resistance training, aerobic training, ischemic stroke, neurological function, motor function, quality of life