Abstract: Objective To investigate the effect of Xiao'er Feire Kechuan Granules Combined with Budesonide on Children with Bronchial Pneumonia. Methods 86 cases of patients with bronchial pneumonia admitted to Xinjiang Changji Prefecture Hospital of TCM from January 2021 to December 2022 were selected, and were divided into two groups randomly. The control group was treated with budesonide alone, and the observation group was pediatric pulmonary hot cough and asthma particles combined with budesonide. Indices related to clinial manifestation, blood gas indices [SpO₂, PaO₂, FiO₂, PaCO₂], lung function indices [VPTEF/VE, RR, TPTEF/TE and VT] and serum indexes [pulmonary surfactant protein D (SP-D), soluble interleukin-2 receptor (sIL-2R), interferon- γ (INF- γ), insulin like growth factor (IGF-Ⅱ)] were detected and compared. Results The effective rate of the observation group was significantly higher than that of the control group (P<0.05). The disappearance time of cough, fever, wheezing and lung rale in the observation group were shorter (P<0.05). After treatment, the SpO₂, PaO₂, OI and PaCO₂ in the two groups were significantly improved (P<0.05), and the observation group were significantly better than those in the control group (P<0.05). After treatment, VPTEF/VE, RR, TPTEF/TE and VT in the two groups were significantly improved (P<0.05), and the observation group were significantly better than those in the control group (P<0.05). After treatment, serum SP-D, sIL-2R, INF-γAnd IGF-Ⅱ levels were significantly improved (P<0.05), and the control group were significantly higher than those in the control group (P<0.05). Conclusion Xiao'er Feire Kechuan Granules combined with budesonide has a significant effect on children with bronchopneumonia, which is worth promoting.

Key words: Xiao'er feire kechuan Granules, budesonide, bronchopneumonia