Abstract: Objective To analyze the application value of zirconia all ceramic restoration in patients with tooth defects. Methods The medical records of 78 patients with tooth defects admitted to Lanshan District People's Hospital in Rizhao from April 2021 to April 2022 were analyzed retrospectively, and they were divided into two groups according to the different repair methods. Among them,40 patients with metal ceramic restorations were included in the control group, and 38 patients with zirconia all ceramic restorations were included in the observation group. Both groups were observed until 6 months after operation. The restorative effect, masticatory function, periodontal health related indicators, levels of inflammatory factors in gingival crevicular fluid and satisfaction were compared between the two groups. Results The proportion of color matching, marginal sealing, normal gingival and complete and stable prosthesis in the observation group were higher than those in the control group, with statistically significant difference (P<0.05);After operation, the masticatory efficiency and bite force of the observation group were higher than those of the control group, and the plaque index (PLI) score, gingival index (GI) score, depth of detection (PD), C-reactive protein (CRP),tumor necrosis factor (TNF-α(TNF-α)、 Interleukin-6 was significantly lower than that of the control group (P<0.05); The satisfaction of the observation group was higher than that of the control group, the difference was statistically significant (P<0.05). Conclusion Zirconia all ceramic restoration has a significant effect in the treatment of patients with tooth defects. It can effectively improve their masticatory function, reduce the level of inflammatory factors, improve periodontal health, and improve patient satisfaction. It has a high clinical application value.

Key words: tooth defect, zirconia all ceramic repair, masticatory function, periodontal health